Induction of angiotensin-converting enzyme after miR-143/145 deletion is critical for impaired smooth muscle contractility

American Journal of Physiology - Cell Physiology

Volumn 307, Issue 12, 2014, Pages C1093-C1101

  Dahan, Diana ^a   Ekman, Mari ^b   Larsson Callerfelt, Anna Karin ^a   Turczyńska, Karolina ^a   Boettger, Thomas ^c   Braun, Thomas ^c   Swärd, Karl ^a   Albinsson, Sebastian ^a  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

Author keywords

Airway; Angiotensin II; Contractile protein; Detrusor; MicroRNA; MiR 145; Myocardin; Smooth muscle; Urinary bladder; Vascular biology

Indexed keywords

ANGIOTENSIN II; CALCIUM CHANNEL L TYPE; CALYCULIN A; CARBACHOL; CIRAZOLINE; DESMIN; DIPEPTIDYL CARBOXYPEPTIDASE; KRUPPEL LIKE FACTOR 4; KRUPPEL LIKE FACTOR 5; LIM KINASE; MESSENGER RNA; MICRORNA 143; MICRORNA 145; MYOCARDIN; PHOSPHATASE; RHO KINASE; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; MICRORNA; MIRN143 MICRORNA, MOUSE; MIRN145 MICRORNA, MOUSE; VASOCONSTRICTOR AGENT;

ACTIN POLYMERIZATION; AIRWAY; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; BLADDER; CELL MEMBRANE DEPOLARIZATION; COMPARATIVE STUDY; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; FEMALE; GENE DELETION; LONG TERM CARE; MALE; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SMOOTH MUSCLE; SMOOTH MUSCLE CONTRACTILITY; TISSUES; UPREGULATION; VASCULAR SMOOTH MUSCLE; ANIMAL; BIOSYNTHESIS; DOSE RESPONSE; DRUG EFFECTS; ENZYME INDUCTION; ENZYMOLOGY; GENETICS; GENOTYPE; KNOCKOUT MOUSE; METABOLISM; MUSCLE CONTRACTION; ORGAN CULTURE TECHNIQUE; PATHOPHYSIOLOGY; RESPIRATORY SYSTEM; SIGNAL TRANSDUCTION; VASOCONSTRICTION;

MUS;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; AORTA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; GENE DELETION; GENOTYPE; MICE, KNOCKOUT; MICRORNAS; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; ORGAN CULTURE TECHNIQUES; PEPTIDYL-DIPEPTIDASE A; PHENOTYPE; RESPIRATORY SYSTEM; SIGNAL TRANSDUCTION; URINARY BLADDER; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS;

EID: 84918778428     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00250.2014     Document Type: Article

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