An Endoplasmic reticulum stress-initiated sphingolipid metabolite, ceramide-1-phosphate, regulates epithelial innate immunity by stimulating ß-defensin production

Molecular and Cellular Biology

Volumn 34, Issue 24, 2014, Pages 4368-4378

  Kim, Young Il ^a,b,c   Park, Kyungho ^a,b,c   Kim, Jong Youl ^b,c   Seo, Ho Seong ^d   Shin, Kyong Oh ^e   Lee, Yong Moon ^e   Holleran, Walter M ^a,b,c   Elias, Peter M ^a,b,c   Uchida, Yoshikazu ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c NORTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION   (United States)

^d Korea Atomic Energy Research Institute   (South Korea)

^e Chungbuk National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE PHOSPHATE; BETA DEFENSIN; CERAMIDE 1 PHOSPHATE; CYCLIC AMP; MESSENGER RNA; SMALL INTERFERING RNA; SPHINGOLIPID; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOSINE 1 PHOSPHATE; STAT3 PROTEIN; THAPSIGARGIN; BETA-DEFENSIN 3, HUMAN; CATHELICIDIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE; CERAMIDE; CERAMIDE 1-PHOSPHATE; CULTURE MEDIUM; DEFB4A PROTEIN, HUMAN; LYSOPHOSPHOLIPID; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INNATE IMMUNITY; KERATINOCYTE; PROMOTER REGION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; STAPHYLOCOCCUS AUREUS; UPREGULATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; CULTURE MEDIUM; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HELA CELL LINE; IMMUNOLOGY; METABOLISM; PHARMACOLOGY; SIGNAL TRANSDUCTION;

STAPHYLOCOCCUS AUREUS;

BETA-DEFENSINS; CATHELICIDINS; CELLS, CULTURED; CERAMIDES; CULTURE MEDIA, CONDITIONED; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; IMMUNITY, INNATE; KERATINOCYTES; LYSOPHOSPHOLIPIDS; SIGNAL TRANSDUCTION; SPHINGOSINE; STAPHYLOCOCCUS AUREUS; THAPSIGARGIN;

EID: 84918770803     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00599-14     Document Type: Article

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