High-throughput screening for integrative biomaterials design: Exploring advances and new trends

Trends in Biotechnology

Volumn 32, Issue 12, 2014, Pages 627-636

  Oliveira, Mariana B ^a   Mano, João F ^a  

^a UNIVERSITY OF MINHO   (Portugal)

Author keywords

Arrays; Biomaterials; Combinatorial; High throughput; Lab on chip testing

Indexed keywords

BIOLOGY; BIOMATERIALS; CELL ENGINEERING; COST ENGINEERING; DATA ACQUISITION; DATA HANDLING; TISSUE;

ARRAYS; BIOLOGICAL ENVIRONMENTS; BIOMATERIALS PROCESSING; COMBINATORIAL; HIGH THROUGHPUT; HIGH THROUGHPUT SCREENING; HIGH-THROUGHPUT APPROACHES; LAB-ON-CHIP TESTING;

TISSUE ENGINEERING;

BIOMATERIAL;

CELL ENCAPSULATION; EVOLUTION; HIGH THROUGHPUT SCREENING; IN VITRO STUDY; IN VIVO STUDY; MICROARRAY ANALYSIS; PRODUCT DEVELOPMENT; REVIEW; TISSUE ENGINEERING; TISSUE REGENERATION; BIOTECHNOLOGY; ISOLATION AND PURIFICATION; PHARMACEUTICS; PROCEDURES; TRENDS;

BIOCOMPATIBLE MATERIALS; BIOTECHNOLOGY; HIGH-THROUGHPUT SCREENING ASSAYS; TECHNOLOGY, PHARMACEUTICAL;

EID: 84918557334     PISSN: 01677799     EISSN: 18793096     Source Type: Journal    
DOI: 10.1016/j.tibtech.2014.09.009     Document Type: Review

References (99)

1. Simon C.G., et al. Combinatorial and high-throughput screening of biomaterials. Adv. Mater. 2011, 23:369-387.
2. Cranford S.W., et al. Materiomics: an -omics approach to biomaterials research. Adv. Mater. 2013, 25:802-824.
3. Schurgers E., et al. Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis. Arthritis Res. Ther. 2010, 12. 10.1186/ar2939.
4. Unadkat H.V., et al. An algorithm-based topographical biomaterials library to instruct cell fate. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:16565-16570.
5. Sala A., et al. Engineering 3D cell instructive microenvironments by rational assembly of artificial extracellular matrices and cell patterning. Integr. Biol. (Camb.) 2011, 3:1102-1111.
6. Gobaa S., et al. Artificial niche microarrays for probing single stem cell fate in high throughput. Nat. Methods 2011, 8:949-955.
7. Ueda E., et al. Emerging applications of superhydrophilic-superhydrophobic micropatterns. Adv. Mater. 2013, 25:1234-1247.
8. Geyer F.L., et al. Superhydrophobic-superhydrophilic micropatterning: towards genome-on-a-chip cell microarrays. Angew. Chem. Int. Ed. Engl. 2011, 50:8424-8427.
9. Ueda E., et al. DropletMicroarray: facile formation of arrays of microdroplets and hydrogel micropads for cell screening applications. Lab Chip 2012, 12:5218-5224.
10. Oliveira M.B., et al. In vivo high-content evaluation of three-dimensional scaffolds biocompatibility. Tissue Eng. Part C: Methods 2014, 10.1089/ten.TEC.2013.0738.
11. Brouzes E., et al. Droplet microfluidic technology for single-cell high-throughput screening. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:14195-14200.
12. Schena M., et al. Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 1995, 270:467-470.
13. Anderson D.G., et al. Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells. Nat. Biotechnol. 2004, 22:863-866.
14. Santos E., et al. Novel advances in the design of three-dimensional bio-scaffolds to control cell fate: translation from 2D to 3D. Trends Biotechnol. 2012, 30:331-341.
15. Discher D.E., et al. Tissue cells feel and respond to the stiffness of their substrate. Science 2005, 310:1139-1143.
16. Kim K.M., et al. Shear stress induced by an interstitial level of slow flow increases the osteogenic differentiation of mesenchymal stem cells through TAZ activation. PLoS ONE 2014, 9. 10.1371/journal.pone.0092427.
17. Stewart M.P., et al. Hydrostatic pressure and the actomyosin cortex drive mitotic cell rounding. Nature 2011, 469:226-230.
18. Wei J., et al. The importance of three-dimensional scaffold structure on stemness maintenance of mouse embryonic stem cells. Biomaterials 2014, 35:7724-7733.
19. Hull R., et al. Microcontact printing: new mastering and transfer techniques for high throughput, resolution and depth of focus. Mater. Sci. Eng. C 2002, 19:383-392.
20. Khan F., et al. Strategies for cell manipulation and skeletal tissue engineering using high-throughput polymer blend formulation and microarray techniques. Biomaterials 2010, 31:2216-2228.
21. Mei Y., et al. Mapping the interactions among biomaterials, adsorbed proteins, and human embryonic stem cells. Adv. Mater. 2009, 21:2781-2786.
22. Tweedie C.A., et al. Combinatorial material mechanics: high-throughput polymer synthesis and nanomechanical screening. Adv. Mater. 2005, 17:2599-2604.
23. Hook A.L., et al. Combinatorial discovery of polymers resistant to bacterial attachment. Nat. Biotechnol. 2012, 30:868-875.
24. Dolatshahi-Pirouz A., et al. A combinatorial cell-laden gel microarray for inducing osteogenic differentiation of human mesenchymal stem cells. Sci. Rep. 2014, 4. 10.1038/srep03896.
25. Akagi T., et al. Inkjet printing of layer-by-layer assembled poly(lactide) stereocomplex with encapsulated proteins. Langmuir 2014, 30:1669-1676.
26. Moon S., et al. Layer by layer three-dimensional tissue epitaxy by cell-laden hydrogel droplets. Tissue Eng. Part C: Methods 2010, 16:157-166.
27. Zhang R., et al. Microarrays of over 2000 hydrogels - identification of substrates for cellular trapping and thermally triggered release. Biomaterials 2009, 30:6193-6201.
28. Suntivich R., et al. Inkjet printing of silk nest arrays for cell hosting. Biomacromolecules 2014, 15:1428-1435.
29. Cui X., et al. Thermal inkjet printing in tissue engineering and regenerative medicine. Recent Pat. Drug Deliv. Formul. 2012, 6:149-155.
30. Guillemot F., et al. High-throughput laser printing of cells and biomaterials for tissue engineering. Acta Biomater. 2010, 6:2494-2500.
31. Ringeisen B.R., et al. Laser printing of pluripotent embryonal carcinoma cells. Tissue Eng. 2004, 10:483-491.
32. Koch L., et al. Laser printing of skin cells and human stem cells. Tissue Eng. Part C: Methods 2010, 16:847-854.
33. Okano K., et al. In situ laser micropatterning of proteins for dynamically arranging living cells. Lab Chip 2013, 13:4078-4086.
34. Ankam S., et al. High throughput screening to investigate the interaction of stem cells with their extracellular microenvironment. Organogenesis 2013, 9:128-142.
35. Yuan B., et al. A general approach for patterning multiple types of cells using holey PDMS membranes and microfluidic channels. Adv. Funct. Mater. 2010, 20:3715-3720.
36. Kang L.F., et al. Cell confinement in patterned nanoliter droplets in a microwell array by wiping. J. Biomed. Mater. Res. A 2010, 93:547-557.
37. Charnley M., et al. Integration column: microwell arrays for mammalian cell culture. Integr. Biol. (Camb.) 2009, 1:625-634.
38. Moraes C., et al. A microfabricated platform for high-throughput unconfined compression of micropatterned biomaterial arrays. Biomaterials 2010, 31:577-584.
39. Yao X., et al. Applications of bio-inspired special wettable surfaces. Adv. Mater. 2011, 23:719-734.
40. Lima A.C., Mano J.F. Micro/nano structured superhydrophobic surfaces in the biomedical field. Part 2: applications overview. Nanomedicine 2015, 10.2217/NNM.14.175.
41. Neto A.I., et al. High-throughput evaluation of interactions between biomaterials, proteins and cells using patterned superhydrophobic substrates. Soft Matter 2011, 7:4147-4151.
42. Oliveira S.M., et al. Chemical modification of bioinspired superhydrophobic polystyrene surfaces to control cell attachment/proliferation. Soft Matter 2011, 7:8932-8941.
43. Ballester-Beltran J., et al. Role of superhydrophobicity in the biological activity of fibronectin at the cell-material interface. Soft Matter 2011, 7:10803-10811.
44. Lourenco B.N., et al. Wettability influences cell behavior on superhydrophobic surfaces with different topographies. Biointerphases 2012, 7. 10.1007/s13758-012-0046-6.
45. Salgado C.L., et al. Combinatorial cell-3D biomaterials cytocompatibility screening for tissue engineering using bioinspired superhydrophobic substrates. Integr. Biol. (Camb.) 2012, 4:318-327.
46. Oliveira M.B., et al. Combinatorial on-chip study of miniaturized 3D porous scaffolds using a patterned superhydrophobic platform. Small 2013, 9:768-778.
47. Oliveira M.B., et al. A combinatorial study of nanocomposite hydrogels: on-chip mechanical/viscoelastic and pre-osteoblast interaction characterization. J. Mater. Chem. B 2014, 2:5627-5638.
48. Lu C.H., et al. Recent progresses in gene delivery-based bone tissue engineering. Biotechnol. Adv. 2013, 31:1695-1706.
49. Lima A.C., et al. Biomimetic methodology to produce polymeric multilayered particles for biotechnological and biomedical applications. Small 2013, 9:2487-2492.
50. Oliveira M.B., et al. On-chip assessment of the protein-release profile from 3D hydrogel arrays. Anal. Chem. 2013, 85:2391-2396.
51. Ranga A., et al. 3D niche microarrays for systems-level analyses of cell fate. Nat. Commun. 2014, 5:4324.
52. Chatterjee K., et al. The effect of 3D hydrogel scaffold modulus on osteoblast differentiation and mineralization revealed by combinatorial screening. Biomaterials 2010, 31:5051-5062.
53. Zonca M.R., et al. High-throughput screening of substrate chemistry for embryonic stem cell attachment, expansion, and maintaining pluripotency. Macromol. Biosci. 2013, 13:177-190.
54. Yang J., et al. A high-throughput assay of cell-surface interactions using topographical and chemical gradients. Adv. Mater. 2009, 21:300-304.
55. He J.K., et al. Microfluidic synthesis of composite cross-gradient materials for investigating cell-biomaterial interactions. Biotechnol. Bioeng. 2011, 108:175-185.
56. Hancock M.J., et al. Surface-tension-driven gradient generation in a fluid stripe for bench-top and microwell applications. Small 2011, 7:892-901.
57. Allazetta S., et al. Programmable microfluidic patterning of protein gradients on hydrogels. Chem. Commun. (Camb.) 2011, 47:191-193.
58. Smith Callahan L.A., et al. Influence of discrete and continuous culture conditions on human mesenchymal stem cell lineage choice in RGD concentration gradient hydrogels. Biomacromolecules 2013, 14:3047-3054.
59. Chatterjee K., et al. Fabricating gradient hydrogel scaffolds for 3D cell culture. Comb. Chem. High Throughput Screen. 2011, 14:227-236.
60. He J., et al. Rapid generation of biologically relevant hydrogels containing long-range chemical gradients. Adv. Funct. Mater. 2010, 20:131-137.
61. Selimovic S., et al. Generating nonlinear concentration gradients in microfluidic devices for cell studies. Anal. Chem. 2011, 83:2020-2028.
62. Almodovar J., et al. Spatial patterning of BMP-2 and BMP-7 on biopolymeric films and the guidance of muscle cell fate. Biomaterials 2014, 35:3975-3985.
63. Castleberry S.A., et al. Capillary flow layer-by-layer: a microfluidic platform for the high-throughput assembly and screening of nanolayered film libraries. ACS Nano 2014, 8:6580-6589.
64. Andreas K., et al. Toward in situ tissue engineering: chemokine-guided stem cell recruitment. Trends Biotechnol. 2014, 32:483-492.
65. Ino K., et al. Cell culture arrays using magnetic force-based cell patterning for dynamic single cell analysis. Lab Chip 2008, 8:134-142.
66. Chung S.E., et al. One-step pipetting and assembly of encoded chemical-laden microparticles for high-throughput multiplexed bioassays. Nat. Commun. 2014, 5. 10.1038/ncomms4468.
67. Leferink A.M., et al. Increased cell seeding efficiency in bioplotted three-dimensional PEOT/PBT scaffolds. J. Tissue Eng. Regen. Med. 2013, 9:1864-1875.
68. Sobral J.M., et al. Three-dimensional plotted scaffolds with controlled pore size gradients: effect of scaffold geometry on mechanical performance and cell seeding efficiency. Acta Biomater. 2011, 7:1009-1018.
69. Zhao S., et al. Off-the-shelf microsponge arrays for facile and efficient construction of miniaturized 3D cellular microenvironments for versatile cell-based assays. Lab Chip 2013, 13:2350-2358.
70. Bettinger C.J., et al. Engineering substrate topography at the micro- and nanoscale to control cell function. Angew. Chem. Int. Ed. Engl. 2009, 48:5406-5415.
71. Nandakumar A., et al. A fast process for imprinting micro and nano patterns on electrospun fiber meshes at physiological temperatures. Small 2013, 9:3405-3409.
72. Levorson E.J., et al. Direct and indirect co-culture of chondrocytes and mesenchymal stem cells for the generation of polymer/extracellular matrix hybrid constructs. Acta Biomater. 2014, 10:1824-1835.
73. Unadkat H.V., et al. A modular versatile chip carrier for high-throughput screening of cell-biomaterial interactions. J. R. Soc. Interface 2013, 10. 10.1098/rsif.2012.0753.
74. Spiller K.L., et al. The role of macrophage phenotype in vascularization of tissue engineering scaffolds. Biomaterials 2014, 35:4477-4488.
75. Lagus T.P., et al. A review of the theory, methods and recent applications of high-throughput single-cell droplet microfluidics. J. Phys. D: Appl. Phys. 2013, 46. 10.1088/0022-3727/46/11/114005.
76. Mazutis L., et al. Single-cell analysis and sorting using droplet-based microfluidics. Nat. Protoc. 2013, 8:870-891.
77. Dendukuri D., et al. Continuous-flow lithography for high-throughput microparticle synthesis. Nat. Mater. 2006, 5:365-369.
78. Lutolf M.P., et al. Designing materials to direct stem-cell fate. Nature 2009, 462:433-441.
79. Tumarkin E., et al. High-throughput combinatorial cell co-culture using microfluidics. Integr. Biol. (Camb.) 2011, 3:653-662.
80. Velasco D., et al. Microfluidic encapsulation of cells in polymer microgels. Small 2012, 8:1633-1642.
81. Gorocs Z., et al. On-chip biomedical imaging. IEEE Rev. Biomed. Eng. 2013, 6:29-46.
82. Neto A.I., et al. Biomimetic miniaturized platform able to sustain arrays of liquid droplets for high-throughput combinatorial tests. Adv. Funct. Mater. 2014, 24:5096-5103.
83. Schonbrun E., et al. High-throughput fluorescence detection using an integrated zone-plate array. Lab Chip 2010, 10:852-856.
84. Zhou J., et al. High-content single-cell analysis on-chip using a laser microarray scanner. Lab Chip 2012, 12:5025-5033.
85. Su T.W., et al. High-throughput lensfree 3D tracking of human sperms reveals rare statistics of helical trajectories. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:16018-16022.
86. Coskun A.F., et al. Lensfree fluorescent on-chip imaging of transgenic Caenorhabditis elegans over an ultra-wide field-of-view. PLoS ONE 2011, 6. 10.1371/journal.pone.0015955.
87. Wei Q.S., et al. On-chip cytometry using plasmonic nanoparticle enhanced lensfree holography. Sci. Rep. 2013, 3. 10.1038/srep01699.
88. Yu H.Y., et al. Functional morphometric analysis in cellular behaviors: shape and size matter. Adv. Healthc. Mater. 2013, 2:1188-1197.
89. Unadkat H.V., et al. High content imaging in the screening of biomaterial-induced MSC behavior. Biomaterials 2013, 34:1498-1505.
90. Smith J.R., et al. Predicting fibrinogen adsorption to polymeric surfaces in silico: a combined method approach. Polymer 2005, 46:4296-4306.
91. Hook A.L., et al. High throughput methods applied in biomaterial development and discovery. Biomaterials 2010, 31:187-198.
92. Oliveira N.M., et al. Two-dimensional open microfluidic devices by tuning the wettability on patterned superhydrophobic polymeric surface. Appl. Phys. Expr. 2010, 3. 10.1143/APEX.3.085205.
93. Song W.L., et al. Bioinspired methodology for preparing magnetic responsive chitosan beads to be integrated in a tubular bioreactor for biomedical applications. Biomed. Mater. 2013, 8. 10.1088/1748-6041/8/4/045008.
94. Kyritsis N., et al. Acute inflammation initiates the regenerative response in the adult zebrafish brain. Science 2012, 338:1353-1356.
95. Ruder W.C., et al. Three-dimensional microfiber devices that mimic physiological environments to probe cell mechanics and signaling. Lab Chip 2012, 12:1775-1779.
96. Khetan S., et al. Patterning hydrogels in three dimensions towards controlling cellular interactions. Soft Matter 2011, 7:830-838.
97. Walther A., et al. Janus particles: synthesis, self-assembly, physical properties, and applications. Chem. Rev. 2013, 113:5194-5261.
98. Lima A.C., et al. Novel methodology based on biomimetic superhydrophobic substrates to immobilize cells and proteins in hydrogel spheres for applications in bone regeneration. Tissue Eng. Part A 2013, 19:1175-1187.
99. Oliveira M.B., et al. Superhydrophobic chips for cell spheroids high-throughput generation and drug screening. ACS Appl. Mater. Interfaces 2014, 6:9488-9495.