메뉴 건너뛰기




Volumn 44, Issue , 2015, Pages 187-194

Astrocytic TNFα regulates the behavioral response to antidepressants

Author keywords

Cytokine; Depression; Desipramine; Fluoxetine; FST; TNF ; TST

Indexed keywords

DESIPRAMINE; FLUOXETINE; MESSENGER RNA; SEROTONIN; TUMOR NECROSIS FACTOR ALPHA; ANTIDEPRESSANT AGENT;

EID: 84918551838     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2014.09.012     Document Type: Article
Times cited : (17)

References (63)
  • 1
    • 0033523473 scopus 로고    scopus 로고
    • Learning abilities, NGF and BDNF brain levels in two lines of TNF-alpha transgenic mice, one characterized by neurological disorders, the other phenotypically normal
    • Aloe L., Properzi F., Probert L., Akassoglou K., Kassiotis G., Micera A., Fiore M. Learning abilities, NGF and BDNF brain levels in two lines of TNF-alpha transgenic mice, one characterized by neurological disorders, the other phenotypically normal. Brain Res. 1999, 840:125-137.
    • (1999) Brain Res. , vol.840 , pp. 125-137
    • Aloe, L.1    Properzi, F.2    Probert, L.3    Akassoglou, K.4    Kassiotis, G.5    Micera, A.6    Fiore, M.7
  • 3
    • 0036293742 scopus 로고    scopus 로고
    • Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation
    • Bajenaru M.L., Zhu Y., Hedrick N.M., Donahoe J., Parada L.F., Gutmann D.H. Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation. Mol. Cell. Biol. 2002, 22:5100-5113.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5100-5113
    • Bajenaru, M.L.1    Zhu, Y.2    Hedrick, N.M.3    Donahoe, J.4    Parada, L.F.5    Gutmann, D.H.6
  • 7
    • 84880395212 scopus 로고    scopus 로고
    • Effects of long-term etanercept treatment on anxiety- and depression-like neurobehaviors in rats
    • Bayramgurler D., Karson A., Ozer C., Utkan T. Effects of long-term etanercept treatment on anxiety- and depression-like neurobehaviors in rats. Physiol. Behav. 2013, 119:145-148.
    • (2013) Physiol. Behav. , vol.119 , pp. 145-148
    • Bayramgurler, D.1    Karson, A.2    Ozer, C.3    Utkan, T.4
  • 9
    • 33646548627 scopus 로고    scopus 로고
    • A new chapter opens in anti-inflammatory treatments: the antidepressant bupropion lowers production of tumor necrosis factor-alpha and interferon-gamma in mice
    • Brustolim D., Ribeiro-dos-Santos R., Kast R.E., Altschuler E.L., Soares M.B. A new chapter opens in anti-inflammatory treatments: the antidepressant bupropion lowers production of tumor necrosis factor-alpha and interferon-gamma in mice. Int. Immunopharmacol. 2006, 6:903-907.
    • (2006) Int. Immunopharmacol. , vol.6 , pp. 903-907
    • Brustolim, D.1    Ribeiro-dos-Santos, R.2    Kast, R.E.3    Altschuler, E.L.4    Soares, M.B.5
  • 10
    • 43049177729 scopus 로고    scopus 로고
    • Peripheral inflammation is associated with altered substantia nigra activity and psychomotor slowing in humans
    • Bryclon L., Harrison N.A., Walker C., Steptoe A., Critchley H.D. Peripheral inflammation is associated with altered substantia nigra activity and psychomotor slowing in humans. Biol. Psychiatry 2008, 63:1022-1029.
    • (2008) Biol. Psychiatry , vol.63 , pp. 1022-1029
    • Bryclon, L.1    Harrison, N.A.2    Walker, C.3    Steptoe, A.4    Critchley, H.D.5
  • 15
    • 84866728940 scopus 로고    scopus 로고
    • Phenelzine (monoamine oxidase inhibitor) increases production of nitric oxide and proinflammatory cytokines via the NF-kappaB pathway in lipopolysaccharide-activated microglia cells
    • Chung H.S., Kim H., Bae H. Phenelzine (monoamine oxidase inhibitor) increases production of nitric oxide and proinflammatory cytokines via the NF-kappaB pathway in lipopolysaccharide-activated microglia cells. Neurochem. Res. 2012, 37:2117-2124.
    • (2012) Neurochem. Res. , vol.37 , pp. 2117-2124
    • Chung, H.S.1    Kim, H.2    Bae, H.3
  • 16
    • 19944380200 scopus 로고    scopus 로고
    • The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice
    • Cryan J.F., Mombereau C., Vassout A. The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. Neurosci. Biobehav. Rev. 2005, 29:571-625.
    • (2005) Neurosci. Biobehav. Rev. , vol.29 , pp. 571-625
    • Cryan, J.F.1    Mombereau, C.2    Vassout, A.3
  • 17
    • 84875235624 scopus 로고    scopus 로고
    • Antidepressants act directly on astrocytes: evidences and functional consequences
    • Czeh B., Di Benedetto B. Antidepressants act directly on astrocytes: evidences and functional consequences. Eur. Neuropsychopharmacol. 2013, 23:171-185.
    • (2013) Eur. Neuropsychopharmacol. , vol.23 , pp. 171-185
    • Czeh, B.1    Di Benedetto, B.2
  • 18
    • 37249094173 scopus 로고    scopus 로고
    • From inflammation to sickness and depression: when the immune system subjugates the brain
    • Dantzer R., O'Connor J.C., Freund G.G., Johnson R.W., Kelley K.W. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat. Rev. Neurosci. 2008, 9:46-57.
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 46-57
    • Dantzer, R.1    O'Connor, J.C.2    Freund, G.G.3    Johnson, R.W.4    Kelley, K.W.5
  • 19
    • 0029081299 scopus 로고
    • Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants
    • Detke M.J., Rickels M., Lucki I. Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants. Psychopharmacology 1995, 121:66-72.
    • (1995) Psychopharmacology , vol.121 , pp. 66-72
    • Detke, M.J.1    Rickels, M.2    Lucki, I.3
  • 20
    • 33748197753 scopus 로고    scopus 로고
    • Antidepressants suppress production of the Th1 cytokine interferon-gamma, independent of monoamine transporter blockade
    • Diamond M., Kelly J.P., Connor T.J. Antidepressants suppress production of the Th1 cytokine interferon-gamma, independent of monoamine transporter blockade. Eur. Neuropsychopharmacol. 2006, 16:481-490.
    • (2006) Eur. Neuropsychopharmacol. , vol.16 , pp. 481-490
    • Diamond, M.1    Kelly, J.P.2    Connor, T.J.3
  • 22
    • 77957231941 scopus 로고    scopus 로고
    • Antidepressant-like effects of an AMPA receptor potentiator under a chronic mild stress paradigm
    • Farley S., Apazoglou K., Witkin J.M., Giros B., Tzavara E.T. Antidepressant-like effects of an AMPA receptor potentiator under a chronic mild stress paradigm. Int. J. Neuropsychopharmacol. 2010, 13:1207-1218.
    • (2010) Int. J. Neuropsychopharmacol. , vol.13 , pp. 1207-1218
    • Farley, S.1    Apazoglou, K.2    Witkin, J.M.3    Giros, B.4    Tzavara, E.T.5
  • 23
    • 0030174305 scopus 로고    scopus 로고
    • Neurobehavioral alterations in developing transgenic mice expressing TNF-alpha in the brain
    • Fiore M., Probert L., Kollias G., Akassoglou K., Alleva E., Aloe L. Neurobehavioral alterations in developing transgenic mice expressing TNF-alpha in the brain. Brain Behav. Immun. 1996, 10:126-138.
    • (1996) Brain Behav. Immun. , vol.10 , pp. 126-138
    • Fiore, M.1    Probert, L.2    Kollias, G.3    Akassoglou, K.4    Alleva, E.5    Aloe, L.6
  • 24
    • 0346992335 scopus 로고    scopus 로고
    • Involvement of tumor necrosis factor alpha in hippocampal development and function
    • Golan H., Levav T., Mendelsohn A., Huleihel M. Involvement of tumor necrosis factor alpha in hippocampal development and function. Cereb. Cortex 2004, 14:97-105.
    • (2004) Cereb. Cortex , vol.14 , pp. 97-105
    • Golan, H.1    Levav, T.2    Mendelsohn, A.3    Huleihel, M.4
  • 25
    • 0041832184 scopus 로고    scopus 로고
    • Possible association between -G308A tumour necrosis factor-alpha gene polymorphism and major depressive disorder in the Korean population
    • Jun T.Y., Pae C.U., Hoon H., Chae J.H., Bahk W.M., Kim K.S., Serretti A. Possible association between -G308A tumour necrosis factor-alpha gene polymorphism and major depressive disorder in the Korean population. Psychiatr. Genet. 2003, 13:179-181.
    • (2003) Psychiatr. Genet. , vol.13 , pp. 179-181
    • Jun, T.Y.1    Pae, C.U.2    Hoon, H.3    Chae, J.H.4    Bahk, W.M.5    Kim, K.S.6    Serretti, A.7
  • 26
    • 84876443867 scopus 로고    scopus 로고
    • Chronic administration of infliximab (TNF-alpha inhibitor) decreases depression and anxiety-like behaviour in rat model of chronic mild stress
    • Karson A., Demirtas T., Bayramgurler D., Balci F., Utkan T. Chronic administration of infliximab (TNF-alpha inhibitor) decreases depression and anxiety-like behaviour in rat model of chronic mild stress. Basic Clin. Pharmacol. Toxicol. 2013, 112:335-340.
    • (2013) Basic Clin. Pharmacol. Toxicol. , vol.112 , pp. 335-340
    • Karson, A.1    Demirtas, T.2    Bayramgurler, D.3    Balci, F.4    Utkan, T.5
  • 30
    • 84875277496 scopus 로고    scopus 로고
    • Antidepressant effects of TNF-alpha blockade in an animal model of depression
    • Krugel U., Fischer J., Radicke S., Sack U., Himmerich H. Antidepressant effects of TNF-alpha blockade in an animal model of depression. J. Psychiatr. Res. 2013, 47:611-616.
    • (2013) J. Psychiatr. Res. , vol.47 , pp. 611-616
    • Krugel, U.1    Fischer, J.2    Radicke, S.3    Sack, U.4    Himmerich, H.5
  • 33
    • 0030819696 scopus 로고    scopus 로고
    • The forced swimming test as a model for core and component behavioral effects of antidepressant drugs
    • Lucki I. The forced swimming test as a model for core and component behavioral effects of antidepressant drugs. Behav. Pharmacol. 1997, 8:523-532.
    • (1997) Behav. Pharmacol. , vol.8 , pp. 523-532
    • Lucki, I.1
  • 34
    • 84876184806 scopus 로고    scopus 로고
    • The pro-inflammatory cytokine TNF-alpha regulates the activity and expression of the serotonin transporter (SERT) in astrocytes
    • Malynn S., Campos-Torres A., Moynagh P., Haase J. The pro-inflammatory cytokine TNF-alpha regulates the activity and expression of the serotonin transporter (SERT) in astrocytes. Neurochem. Res. 2013, 38:694-704.
    • (2013) Neurochem. Res. , vol.38 , pp. 694-704
    • Malynn, S.1    Campos-Torres, A.2    Moynagh, P.3    Haase, J.4
  • 35
    • 0033281948 scopus 로고    scopus 로고
    • Mood and cognitive disorders in cancer patients receiving cytokine therapy
    • Meyers C.A. Mood and cognitive disorders in cancer patients receiving cytokine therapy. Adv. Exp. Med. Biol. 1999, 461:75-81.
    • (1999) Adv. Exp. Med. Biol. , vol.461 , pp. 75-81
    • Meyers, C.A.1
  • 36
    • 63449122724 scopus 로고    scopus 로고
    • Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression
    • Miller A.H., Maletic V., Raison C.L. Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression. Biol. Psychiatry 2009, 65:732-741.
    • (2009) Biol. Psychiatry , vol.65 , pp. 732-741
    • Miller, A.H.1    Maletic, V.2    Raison, C.L.3
  • 37
    • 0028865803 scopus 로고
    • Tumor necrosis factor-alpha and basic fibroblast growth factor decrease glial fibrillary acidic protein and its encoding mRNA in astrocyte cultures and glioblastoma cells
    • Murphy G.M., Lee Y.L., Jia X.C., Yu A.C., Majewska A., Song Y., Schmidt K., Eng L.F. Tumor necrosis factor-alpha and basic fibroblast growth factor decrease glial fibrillary acidic protein and its encoding mRNA in astrocyte cultures and glioblastoma cells. J. Neurochem. 1995, 65:2716-2724.
    • (1995) J. Neurochem. , vol.65 , pp. 2716-2724
    • Murphy, G.M.1    Lee, Y.L.2    Jia, X.C.3    Yu, A.C.4    Majewska, A.5    Song, Y.6    Schmidt, K.7    Eng, L.F.8
  • 38
    • 33745247187 scopus 로고    scopus 로고
    • Plasma levels of adiponectin and tumor necrosis factor-alpha in patients with remitted major depression receiving long-term maintenance antidepressant therapy
    • Narita K., Murata T., Takahashi T., Kosaka H., Omata N., Wada Y. Plasma levels of adiponectin and tumor necrosis factor-alpha in patients with remitted major depression receiving long-term maintenance antidepressant therapy. Prog. Neuropsychopharmacol. Biol. Psychiatry 2006, 30:1159-1162.
    • (2006) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.30 , pp. 1159-1162
    • Narita, K.1    Murata, T.2    Takahashi, T.3    Kosaka, H.4    Omata, N.5    Wada, Y.6
  • 39
    • 33845213789 scopus 로고    scopus 로고
    • Plasma cytokine profiles in depressed patients who fail to respond to selective serotonin reuptake inhibitor therapy
    • O'Brien S.M., Scully P., Fitzgerald P., Scott L.V., Dinan T.G. Plasma cytokine profiles in depressed patients who fail to respond to selective serotonin reuptake inhibitor therapy. J. Psychiatr. Res. 2007, 41:326-331.
    • (2007) J. Psychiatr. Res. , vol.41 , pp. 326-331
    • O'Brien, S.M.1    Scully, P.2    Fitzgerald, P.3    Scott, L.V.4    Dinan, T.G.5
  • 40
    • 36549030795 scopus 로고    scopus 로고
    • Stress, depression, and neuroplasticity: a convergence of mechanisms
    • Pittenger C., Duman R.S. Stress, depression, and neuroplasticity: a convergence of mechanisms. Neuropsychopharmacology 2008, 33:88-109.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 88-109
    • Pittenger, C.1    Duman, R.S.2
  • 41
    • 0017651126 scopus 로고
    • Behavioral despair in mice: a primary screening test for antidepressants
    • Porsolt R.D., Bertin A., Jalfre M. Behavioral despair in mice: a primary screening test for antidepressants. Arch. Int. Pharmacodyn. Ther. 1977, 229:327-336.
    • (1977) Arch. Int. Pharmacodyn. Ther. , vol.229 , pp. 327-336
    • Porsolt, R.D.1    Bertin, A.2    Jalfre, M.3
  • 42
    • 84871986003 scopus 로고    scopus 로고
    • A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers
    • Raison C.L., Rutherford R.E., Woolwine B.J., Shuo C., Schettler P., Drake D.F., Haroon E., Miller A.H. A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers. JAMA Psychiatry 2013, 70:31-41.
    • (2013) JAMA Psychiatry , vol.70 , pp. 31-41
    • Raison, C.L.1    Rutherford, R.E.2    Woolwine, B.J.3    Shuo, C.4    Schettler, P.5    Drake, D.F.6    Haroon, E.7    Miller, A.H.8
  • 44
    • 4243130499 scopus 로고    scopus 로고
    • Brain-derived tumor necrosis factor-alpha and its involvement in noradrenergic neuron functioning involved in the mechanism of action of an antidepressant
    • Reynolds J.L., Ignatowski T.A., Sud R., Spengler R.N. Brain-derived tumor necrosis factor-alpha and its involvement in noradrenergic neuron functioning involved in the mechanism of action of an antidepressant. J. Pharmacol. Exp. Ther. 2004, 310:1216-1225.
    • (2004) J. Pharmacol. Exp. Ther. , vol.310 , pp. 1216-1225
    • Reynolds, J.L.1    Ignatowski, T.A.2    Sud, R.3    Spengler, R.N.4
  • 45
    • 19444365126 scopus 로고    scopus 로고
    • An antidepressant mechanism of desipramine is to decrease tumor necrosis factor-alpha production culminating in increases in noradrenergic neurotransmission
    • Reynolds J.L., Ignatowski T.A., Sud R., Spengler R.N. An antidepressant mechanism of desipramine is to decrease tumor necrosis factor-alpha production culminating in increases in noradrenergic neurotransmission. Neuroscience 2005, 133:519-531.
    • (2005) Neuroscience , vol.133 , pp. 519-531
    • Reynolds, J.L.1    Ignatowski, T.A.2    Sud, R.3    Spengler, R.N.4
  • 47
    • 84878379500 scopus 로고    scopus 로고
    • From pathophysiology to novel antidepressant drugs: glial contributions to the pathology and treatment of mood disorders
    • Sanacora G., Banasr M. From pathophysiology to novel antidepressant drugs: glial contributions to the pathology and treatment of mood disorders. Biol. Psychiatry 2013, 73:1172-1179.
    • (2013) Biol. Psychiatry , vol.73 , pp. 1172-1179
    • Sanacora, G.1    Banasr, M.2
  • 48
    • 0026353721 scopus 로고
    • Tumor necrosis factor-induced proliferation of astrocytes from mature brain is associated with down-regulation of glial fibrillary acidic protein mRNA
    • Selmaj K., Shafit-Zagardo B., Aquino D.A., Farooq M., Raine C.S., Norton W.T., Brosnan C.F. Tumor necrosis factor-induced proliferation of astrocytes from mature brain is associated with down-regulation of glial fibrillary acidic protein mRNA. J. Neurochem. 1991, 57:823-830.
    • (1991) J. Neurochem. , vol.57 , pp. 823-830
    • Selmaj, K.1    Shafit-Zagardo, B.2    Aquino, D.A.3    Farooq, M.4    Raine, C.S.5    Norton, W.T.6    Brosnan, C.F.7
  • 49
    • 33646101010 scopus 로고    scopus 로고
    • TNFalpha signaling in depression and anxiety: behavioral consequences of individual receptor targeting
    • Simen B.B., Duman C.H., Simen A.A., Duman R.S. TNFalpha signaling in depression and anxiety: behavioral consequences of individual receptor targeting. Biol. Psychiatry 2006, 59:775-785.
    • (2006) Biol. Psychiatry , vol.59 , pp. 775-785
    • Simen, B.B.1    Duman, C.H.2    Simen, A.A.3    Duman, R.S.4
  • 52
    • 33646199097 scopus 로고    scopus 로고
    • Synaptic scaling mediated by glial TNF-alpha
    • Stellwagen D., Malenka R.C. Synaptic scaling mediated by glial TNF-alpha. Nature 2006, 440:1054-1059.
    • (2006) Nature , vol.440 , pp. 1054-1059
    • Stellwagen, D.1    Malenka, R.C.2
  • 53
    • 0021990491 scopus 로고
    • The tail suspension test: a new method for screening antidepressants in mice
    • Steru L., Chermat R., Thierry B., Simon P. The tail suspension test: a new method for screening antidepressants in mice. Psychopharmacology 1985, 85:367-370.
    • (1985) Psychopharmacology , vol.85 , pp. 367-370
    • Steru, L.1    Chermat, R.2    Thierry, B.3    Simon, P.4
  • 54
    • 0347604853 scopus 로고    scopus 로고
    • Increased serum tumor necrosis factor-alpha levels and treatment response in major depressive disorder
    • Tuglu C., Kara S.H., Caliyurt O., Vardar E., Abay E. Increased serum tumor necrosis factor-alpha levels and treatment response in major depressive disorder. Psychopharmacology 2003, 170:429-433.
    • (2003) Psychopharmacology , vol.170 , pp. 429-433
    • Tuglu, C.1    Kara, S.H.2    Caliyurt, O.3    Vardar, E.4    Abay, E.5
  • 55
    • 84857192442 scopus 로고    scopus 로고
    • A comparative examination of the anti-inflammatory effects of SSRI and SNRI antidepressants on LPS stimulated microglia
    • Tynan R.J., Weidenhofer J., Hinwood M., Cairns M.J., Day T.A., Walker F.R. A comparative examination of the anti-inflammatory effects of SSRI and SNRI antidepressants on LPS stimulated microglia. Brain Behav. Immun. 2012, 26:469-479.
    • (2012) Brain Behav. Immun. , vol.26 , pp. 469-479
    • Tynan, R.J.1    Weidenhofer, J.2    Hinwood, M.3    Cairns, M.J.4    Day, T.A.5    Walker, F.R.6
  • 56
    • 29844440963 scopus 로고    scopus 로고
    • Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial
    • Tyring S., Gottlieb A., Papp K., Gordon K., Leonardi C., Wang A., Lalla D., Woolley M., Jahreis A., Zitnik R., et al. Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial. Lancet 2006, 367:29-35.
    • (2006) Lancet , vol.367 , pp. 29-35
    • Tyring, S.1    Gottlieb, A.2    Papp, K.3    Gordon, K.4    Leonardi, C.5    Wang, A.6    Lalla, D.7    Woolley, M.8    Jahreis, A.9    Zitnik, R.10
  • 58
    • 79959343388 scopus 로고    scopus 로고
    • Antidepressant effects of selective serotonin reuptake inhibitors (SSRIs) are attenuated by antiinflammatory drugs in mice and humans
    • Warner-Schmidt J.L., Vanover K.E., Chen E.Y., Marshall J.J., Greengard P. Antidepressant effects of selective serotonin reuptake inhibitors (SSRIs) are attenuated by antiinflammatory drugs in mice and humans. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:9262-9267.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 9262-9267
    • Warner-Schmidt, J.L.1    Vanover, K.E.2    Chen, E.Y.3    Marshall, J.J.4    Greengard, P.5
  • 59
    • 0030220185 scopus 로고    scopus 로고
    • Tricyclic antidepressants inhibit IL-6, IL-1 beta and TNF-alpha release in human blood monocytes and IL-2 and interferon-gamma in T cells
    • Xia Z., DePierre J.W., Nassberger L. Tricyclic antidepressants inhibit IL-6, IL-1 beta and TNF-alpha release in human blood monocytes and IL-2 and interferon-gamma in T cells. Immunopharmacology 1996, 34:27-37.
    • (1996) Immunopharmacology , vol.34 , pp. 27-37
    • Xia, Z.1    DePierre, J.W.2    Nassberger, L.3
  • 60
    • 0034333060 scopus 로고    scopus 로고
    • Neurobehavioral alterations in mice with a targeted deletion of the tumor necrosis factor-alpha gene: implications for emotional behavior
    • Yamada K., Iida R., Miyamoto Y., Saito K., Sekikawa K., Seishima M., Nabeshima T. Neurobehavioral alterations in mice with a targeted deletion of the tumor necrosis factor-alpha gene: implications for emotional behavior. J. Neuroimmunol. 2000, 111:131-138.
    • (2000) J. Neuroimmunol. , vol.111 , pp. 131-138
    • Yamada, K.1    Iida, R.2    Miyamoto, Y.3    Saito, K.4    Sekikawa, K.5    Seishima, M.6    Nabeshima, T.7
  • 62
    • 79960884919 scopus 로고    scopus 로고
    • Pro- and anti-inflammatory cytokines expression in rat's brain and spleen exposed to chronic mild stress: involvement in depression
    • You Z., Luo C., Zhang W., Chen Y., He J., Zhao Q., Zuo R., Wu Y. Pro- and anti-inflammatory cytokines expression in rat's brain and spleen exposed to chronic mild stress: involvement in depression. Behav. Brain Res. 2011, 225:135-141.
    • (2011) Behav. Brain Res. , vol.225 , pp. 135-141
    • You, Z.1    Luo, C.2    Zhang, W.3    Chen, Y.4    He, J.5    Zhao, Q.6    Zuo, R.7    Wu, Y.8
  • 63
    • 33748808678 scopus 로고    scopus 로고
    • The proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha activate serotonin transporters
    • Zhu C.B., Blakely R.D., Hewlett W.A. The proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha activate serotonin transporters. Neuropsychopharmacology 2006, 31:2121-2131.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2121-2131
    • Zhu, C.B.1    Blakely, R.D.2    Hewlett, W.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.