Increased serum tumor necrosis factor-alpha levels and treatment response in major depressive disorder

Psychopharmacology

Volumn 170, Issue 4, 2003, Pages 429-433

  Tuglu, Cengiz ^a   Kara, S Hakan ^a   Caliyurt, Okan ^a   Vardar, Erdal ^a   Abay, Ercan ^a  

^a TRAKYA UNIVERSITY   (Turkey)

Author keywords

Cytokine; Major depression; SSRI; Treatment response; Tumor necrosis factor

Indexed keywords

ANTIDEPRESSANT AGENT; BENZODIAZEPINE; C REACTIVE PROTEIN; CITALOPRAM; CYTOKINE; FLUOXETINE; FLUVOXAMINE; PAROXETINE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CHEMOLUMINESCENCE; CLINICAL ARTICLE; CONTROLLED STUDY; DEPRESSION; ENZYME IMMUNOASSAY; FEMALE; HUMAN; IMMUNE RESPONSE; IMMUNE SYSTEM; LEUKOCYTE COUNT; MAJOR DEPRESSION; MALE; MENTAL DISEASE; PRIORITY JOURNAL; PSYCHOPHARMACOTHERAPY; TREATMENT OUTCOME;

ADULT; BLOOD SEDIMENTATION; C-REACTIVE PROTEIN; CASE-CONTROL STUDIES; DEPRESSIVE DISORDER; FEMALE; HUMANS; LEUKOCYTE COUNT; MALE; SEROTONIN UPTAKE INHIBITORS; SEVERITY OF ILLNESS INDEX; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0347604853     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-003-1566-z     Document Type: Article

References (41)

1. Ader R, Cohen N, Felten D (1995) Psychoneuroimmunology: interactions between the nervous system and the immune system. Lancet 345:99-103
2. Anisman H, Ravindran AV, Griffiths J, Merali Z (1999) Interleukin-1 beta production in dysthymia before and after pharmacotherapy. Biol Psychiatry 46:1649-1655
3. Beck A (1961) An inventory for measuring depression. Arch Gen Psychiatry 4:561-571
4. Berk M, Wadee AA, Kuschke RH, O'Neill-Kerr A (1997) Acute phase proteins in major depression. J Psychosom Res 43:529-534
5. Brambilla F, Maggioni M (1998) Blood levels of cytokines in elderly patients with major depressive disorder. Acta Psychiatr Scand 97:309-313
6. Capuron L, Dantzer R (2003) Cytokines and depression: the need for a new paradigm. Brain Behav Immun 17:119-124
7. beta in the rat. Psychopharmacology 154:50-60
8. Connor TJ, Leonard BE (1998) Depression, stress and immunological activation: the role of cytokines in depressive disorders. Life Sci 62:583-606
9. Dantzer R (2001) Cytokine-induced sickness behavior: where do we stand? Brain Behav Immun 15:7-24
10. Dantzer R, Wollman E, Vitkovic L, Yirmiya R (1999) Cytokines and depression: fortuitous or causative association? Mol Psychiatry 4:328-332
11. Frommberger UH, Bauer J, Haselbauer P, Fraulin A, Riemann D, Berger M (1997) Interleukin-6 (IL-6) plasma levels in depression and schizophrenia: comparison between the acute state and after remission. Eur Arch Psychiatry Clin Neurosci 247:228-233
12. Haack M, Hinze-Selch D, Fenzel T, Kraus T, Kuhn M, Schuld A, Pollmacher T (1999) Plasma levels of cytokines and soluble cytokine receptors in psychiatric patients upon hospital admission: effects of confounding factors and diagnosis. J Psychiatr Res 33:407-418
13. Hamilton M (1960) A rating scale for depression. J Neurol Neurosurg Psychiat 23:56-62
14. Kelley KW, Bluthe RM, Dantzer R, Zhou JH, Shen WH, Johnson RW, Broussard SR (2003) Cytokine-induced sickness behavior. Brain Behav Immun 17:S112-S118
15. Konsman JP, Parnet P, Dantzer R (2002) Cytokine-induced sickness behaviour: mechanisms and implications. Trends Neurosci 25:154-159
16. Kronfol Z, Remick DG (2000) Cytokines and the brain: implications for clinical psychiatry. Am J Psychiatry 157:683-694
17. Landmann R, Schaub B, Link S, Wacker HR (1997) Unaltered monocyte function in patients with major depression before and after three months of antidepressive therapy. Biol Psychiatry 41:675-681
18. Lanquillon S, Krieg JC, Bening-Abu-Shach U, Vedder H (2000) Cytokine production and treatment response in major depressive disorder. Neuropsychopharmacology 22:370-379
19. Leonard BE (2001) The immune system, depression and the action of antidepressants. Prog Neuropsychopharmacol Biol Psychiatry 25:767-780
20. Maes M, Scharpe S, Van Grootel L, Uyttenbroeck W, Cooreman W, Cosyns P, Suy E (1992) Higher alpha 1-antitrypsin, haptoglobin, ceruloplasmin and lower retinol binding protein plasma levels during depression: further evidence for the existence of an inflammatory response during that illness. J Affect Disord 24:183-192
21. Maes M, Meltzer HY, Bosmans E, Bergmans R, Vandoolaeghe E, Ranjan R, Desnyder R (1995) Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression. J Affect Disord 34:301-309
22. Maes M, Song C, Lin AH, Bonaccorso S, Kenis G, De Jongh R, Bosmans E, Scharpe S (1999) Negative immunoregulatory effects of antidepressants: inhibition of interferon-gamma and stimulation of interleukin-10 secretion. Neuropsychopharmacology 20:370-379
23. Maier SF, Watkins LR (1998) Cytokines for psychologists: implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition. Psychol Rev 105:83-107
24. Mikova O, Yakimova R, Bosmans E, Kenis G, Maes M (2001) Increased serum tumor necrosis factor alpha concentrations in major depression and multiple sclerosis. Eur Neuropsychopharmacol 11:203-208
25. beta in major and postviral depression. Acta Psychiatr Scand 103:226-228
26. Papanicolaou DA, Wilder RL, Manolagas SC, Chrousos GP (1998) The pathophysiologic roles of interleukin-6 in human disease. Ann Int Med 128:127-137
27. Rothermundt M, Arolt V, Peters M, Gutbrodt H, Fenker J, Kersting A, Kirchner H (2001) Inflammatory markers in major depression and melancholia. J Affect Disord 63:93-102
28. Seidel A, Arolt V, Hunstiger M, Rink L, Behnisch A, Kirchner H (1996a) Increased CD56+ natural killer cells and related cytokines in major depression. Clin Immunol Immunopathol 78:83-85
29. Seidel A, Arolt V, Hunstiger M, Rink L, Behnisch A, Kirchner H (1996b) Major depressive disorder is associated with elevated monocyte counts. Acta Psychiatr Scand 94:198-204
30. Shen Y, Connor TJ, Nolan Y, Kelly JP, Leonard BE (1999) Differential effect of chronic antidepressant treatments on lipopolysaccharide-induced depressive-like behavioural symptoms in the rat. Life Sci 65:1773-1786
31. Sluzewska A, Rybakowski J, Bosmans E, Sobieska M, Berghmans R, Maes M, Wiktorowicz K (1996a) Indicators of immune activation in major depression. Psychiatry Res 64:161-167
32. Sluzewska A, Rybakowski JK, Sobieska M, Wiktorowicz K (1996b) Concentration and microheterogeneity glycophorms of alpha-1-acid glycoprotein in major depressive disorder. J Affect Disord 39:149-155
33. Smith RS (1991) The macrophage theory of depression. Med Hypoth 35:298-306
34. Song C, Leonard BE (2000) Fundamentals of psychoneuroimmunology. Wiley, Chichester
35. Song C, Dinan T, Leonard BE (1994) Changes in immunoglobulin, complement and acute phase protein levels in the depressed patients and normal controls. J Affect Disord 30:283-288
36. Song C, Lin A, Bonaccorso S, Heide C, Verkerk R, Kenis G, Bosmans E, Scharpe S, Whelan A, Cosyns P, De Jongh R, Maes M (1998) The inflammatory response system and the availability of plasma tryptophan in patients with primary sleep disorders and major depression. J Affect Disord 49:211-219
37. Sorias S, Saygili R, Elbi H, et al (1988) DSM-III-R Yapilandirilmis Klinik Görüsmesi Türkce Versiyonu SCID-I ve SCID-II. Ege Universitesi Matbaasi, Bornova
38. Watkins LR, Maier SF, Goehler LE (1995) Cytokine-to-brain communication: a review and analysis of alternative mechanisms. Life Sci 57:1011-1026
39. Xia Z, DePierre JW, Nassberger L (1996) Tricyclic antidepressants inhibit IL-6, IL-1 beta and TNF-alpha release in human blood monocytes and IL-2 and interferon-gamma in T cells. Immunopharmacology 34:27-37
40. Yirmiya R (1996) Endotoxin produces a depressive-like episode in rats. Brain Res 711:163-174
41. Yirmiya R, Weidenfeld J, Barak O, Avitsur R, Pollak Y, Gallily R, Wohlman A, Ovadia H, Ben Hur T (1999) The role of brain cytokines in mediating the behavioral and neuroendocrine effects of intracerebral mycoplasma fermentans. Brain Res 829:28-38