Chemoenzymatic strategy for the synthesis of site-specifically labeled immunoconjugates for multimodal PET and optical imaging

Bioconjugate Chemistry

Volumn 25, Issue 12, 2014, Pages 2123-2128

  Zeglis, Brian M ^a   Davis, Charles B ^a   Abdel Atti, Dalya ^a   Carlin, Sean D ^a   Chen, Aimei ^b   Aggeler, Robert ^b   Agnew, Brian J ^b   Lewis, Jason S ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Thermo Fisher Scientific   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; CHAINS; CHELATION; DISEASES; FLUORESCENCE IMAGING; INFRARED DEVICES; OPTICAL IMAGE STORAGE; POLYSACCHARIDES; POSITRONS;

ALEXA FLUOR; BIO-CONJUGATION; GLYCANS; HEAVY CHAIN; HIGH AFFINITY; HIGH SELECTIVITY; IMMUNOCONJUGATE; IMMUNOREACTIVITIES; MULTI-MODAL; SURGICAL TREATMENT;

POSITRON EMISSION TOMOGRAPHY;

ALEXA FLUOR 680; ANTIBODY CONJUGATE; AZIDE; CANCER ANTIBODY; DEFEROXAMINE; FLUORESCENT DYE; GALACTOSE; GALACTOSIDASE; GLYCAN; HUA33 ANTIBODY; SUGAR; UNCLASSIFIED DRUG; ZIRCONIUM; ZIRCONIUM 89; POLYSACCHARIDE; RADIOISOTOPE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER MODEL; CANCER SCINTISCANNING; COLORECTAL CANCER; CONTROLLED STUDY; DRUG SYNTHESIS; FLUORESCENCE IMAGING; IMMUNOREACTIVITY; IN VIVO STUDY; ISOTOPE LABELING; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; POSITRON EMISSION TOMOGRAPHY; ANIMAL; CHEMISTRY; COLORECTAL NEOPLASMS; DRUG SCREENING; HUMAN; IMMUNOLOGY; MULTIMODAL IMAGING; NEOPLASMS, EXPERIMENTAL; PROCEDURES; TISSUE DISTRIBUTION;

ALEXA; MUS MUSCULUS;

ANIMALS; COLORECTAL NEOPLASMS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLUORESCENT DYES; GALACTOSE; HUMANS; IMMUNOCONJUGATES; MICE; MULTIMODAL IMAGING; NEOPLASMS, EXPERIMENTAL; OPTICAL IMAGING; POLYSACCHARIDES; POSITRON-EMISSION TOMOGRAPHY; RADIOISOTOPES; TISSUE DISTRIBUTION; XENOGRAFT MODEL ANTITUMOR ASSAYS; ZIRCONIUM;

EID: 84918536144     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc500499h     Document Type: Article

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