Dual functional molecular imaging probe targeting CD20 with PET and optical imaging

Oncology Reports

Volumn 22, Issue 1, 2009, Pages 115-119

  Paudyal, Pramila ^a   Paudyal, Bishnuhari ^a   Iida, Yasuhiko ^a   Oriuchi, Noboru ^a   Hanaoka, Hirofumi ^a   Tominaga, Hideyuki ^a   Ishikita, Tomohiro ^a   Yoshioka, Hiroki ^a   Higuchi, Tetsuya ^a   Endo, Keigo ^a  

^a GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

64Cu; CD20; Lymphoma; Monoclonal antibody; Near infrared fluorescence; PET

Indexed keywords

CD20 ANTIGEN; COPPER 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID MONOCLONAL ANTIBODY NUB2 ALEXA FLUOR 750 CU 64; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; EX VIVO STUDY; FEASIBILITY STUDY; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; INSTRUMENT VALIDATION; LYMPHOMA; MOLECULAR IMAGING; MOLECULAR PROBE; MOUSE; NEAR INFRARED SPECTROSCOPY; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOACTIVITY; RADIOCHEMISTRY; RADIOLOGICAL PARAMETERS;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD20; CELL LINE, TUMOR; CHELATING AGENTS; COPPER RADIOISOTOPES; FEASIBILITY STUDIES; FEMALE; FLUORESCENT DYES; HETEROCYCLIC COMPOUNDS, 1-RING; HUMANS; LYMPHOMA; MICE; MICE, INBRED BALB C; MICE, NUDE; MOLECULAR PROBE TECHNIQUES; POSITRON-EMISSION TOMOGRAPHY; REPRODUCIBILITY OF RESULTS; SPECTROSCOPY, NEAR-INFRARED; SUCCINIMIDES; TIME FACTORS;

EID: 68249135760     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000413     Document Type: Article

References (17)

1. Gurfinkel M, Ke S, Wen X, Li C and Sevick-Muraca EM: Near-infrared fluorescence optical imaging and tomography. Dis Markers 19: 107-121, 2003-2004.
2. Mahmood U, Tung CH, Bogdanov A Jr and Weissleder R: Near-infrared optical imaging of protease activity for tumor detection. Radiology 213: 866-870, 1999.
3. Ke S, Wen X, Gurfinkel M, Charnsangavej C, Wallace S, Sevick-Muraca EM and Li C: Near-infrared optical imaging of epidermal growth factor receptor in breast cancer xenografts. Cancer Res 63: 7870-7875, 2003.
4. 64Cu-TETA-octreotide as a PET imaging agent for patients with neuroendocrine tumors. J Nucl Med 42: 213-221, 2001.
5. Culver J, Akers W and Achilefu S: Multimodality molecular imaging with combined optical and SPECT/PET modalities. J Nucl Med 49: 169-172, 2008.
6. Li C, Wang W, Wu Q, Ke S, Houston J, Sevick-Muraca E, Dong L, Chow D, Charnsangavej C and Gelovani JG: Dual optical and nuclear imaging in human melanoma xenografts using a single targeted imaging probe. Nucl Med Biol 33: 349-358, 2006.
7. Wang W, Ke S, Kwon S, Yallampalli S, Cameron AG, Adams KE, Mawad ME and Sevick-Muraca EM: A new optical and nuclear dual-labeled imaging agent targeting interleukin 11 receptor alpha-chain. Bioconjug Chem 18: 397-402, 2007.
8. Cai W, Chen K, Li ZB, Gambhir SS and Chen X: Dual-function probe for PET and near-infrared fluorescence imaging of tumor vasculature. J Nucl Med 48: 1862-1870, 2007.
9. Chen K, Li ZB, Wang H, Cai W and Chen X: Dual-modality optical and positron emission tomography imaging of vascular endothelial growth factor receptor on tumor vasculature using quantum dots. Eur J Nucl Med Mol Imaging 35: 2235-2244, 2008.
10. Sampath L, Kwon S, Ke S, Wang W, Schiff R, Mawad ME and Sevick-Muraca EM: Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer. J Nucl Med 48: 1501-1510, 2007.
11. 64Cu for tumor imaging and therapy. J Nucl Med 44: 1284-1292, 2003.
12. Oriuchi N, Higuchi T, Hanaoka H, Iida Y and Endo K: Current status of cancer therapy with radiolabeled monoclonal antibody. Ann Nucl Med 19: 355-365, 2005.
13. Cai W and Chen X: Multimodality molecular imaging of tumor angiogenesis. J Nucl Med 49: S113-S128, 2008.
14. Schipper ML, Cheng Z, Lee SW, Bentolila LA, Iyer G, Rao J, Chen X, Wu AM, Weiss S and Gambhir SS: microPET-based biodistribution of quantum dots in living mice. J Nucl Med 48: 1511-1518, 2007.
15. Anderson CJ, Connett JM, Schwarz SW, Rocque PA, Guo LW, Philpott GW, Zinn KR, Meares CF and Welch MJ: Copper-64-labeled antibodies for PET imaging. J Nucl Med 33: 1685-1691, 1992.
16. Bass LA, Wang M, Welch MJ and Anderson CJ: In vivo transchelation of copper-64 from TETA-octreotide to superoxide dismutase in rat liver. Bioconjug Chem 11: 527-532, 2000.
17. Knoess C, Siegel S, Smith A, Newport D, Richerzhagen N, Winkeler A, Jacobs A, Goble RN, Graf R, Wienhard K and Heiss WD: Performance evaluation of the microPET R4 PET scanner for rodents. Eur J Nucl Med Mol Imaging 30: 737-747, 2003.