Identification of human liver microsomal proteins adducted by a reactive metabolite using shotgun proteomics

Chemical Research in Toxicology

Volumn 27, Issue 9, 2014, Pages 1537-1546

  Yang, Yanou ^a   Xiao, Qing ^a   Humphreys, W Griffith ^a   Dongre, Ashok ^a   Shu, Yue Zhong ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; LIVER PROTEIN; REACTIVE OXYGEN METABOLITE; BENZOTHIAZOLE; BENZOTHIAZOLE DERIVATIVE; PEPTIDE; PROTEIN;

ARTICLE; COVALENT BOND; HUMAN; LIVER MICROSOME; PROTEIN ANALYSIS; PROTEIN MODIFICATION; PROTEIN STRUCTURE; PROTEOMICS; SOLUBILIZATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; TANDEM MASS SPECTROMETRY;

BENZOTHIAZOLES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; MICROSOMES, LIVER; PEPTIDES; PROTEINS; PROTEOMICS; TANDEM MASS SPECTROMETRY;

EID: 84918496814     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx500181p     Document Type: Article

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