miR-185-3p regulates nasopharyngeal carcinoma radioresistance by targeting WNT2B in vitro

Cancer Science

Volumn 105, Issue 12, 2014, Pages 1560-1568

  Li, Guo ^a,b   Wang, Yunyun ^a,b   Liu, Yong ^a,b   Su, Zhongwu ^a,b   Liu, Chao ^a,b   Ren, Shuling ^a,b   Deng, Tengbo ^a,b   Huang, Donghai ^a,b   Tian, Yongquan ^a,b   Qiu, Yuanzheng ^a,b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b Otolaryngology Major Disease Research Key Laboratory of Hunan Province   (China)

Author keywords

Epithelial mesenchymal transition; MiR 185 3p; Nasopharyngeal carcinoma; Radioresistance; WNT2B

Indexed keywords

GLYCOPROTEIN; MICRORNA; MIRN185 MICRORNA, HUMAN; WNT PROTEIN; WNT2B PROTEIN, HUMAN;

EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IN VITRO STUDY; METABOLISM; NASOPHARYNGEAL NEOPLASMS; RADIATION DOSE; RADIATION RESPONSE; TUMOR CELL LINE;

CELL LINE, TUMOR; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOPROTEINS; HUMANS; IN VITRO TECHNIQUES; MICRORNAS; NASOPHARYNGEAL NEOPLASMS; RADIATION TOLERANCE; WNT PROTEINS;

EID: 84917743492     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/cas.12555     Document Type: Article

References (43)

1. Wei WI, Sham JS. Nasopharyngeal carcinoma. Lancet 2005; 365: 2041-54.
2. Chang JT, Ko JY, Hong RL. Recent advances in the treatment of nasopharyngeal carcinoma. J Formos Med Assoc 2004; 103: 496-510.
3. Mostafa E, Nasar MN, Rabie NA, Ibrahim SA, Barakat HM, Rabie AN. Induction chemotherapy with paclitaxel and cisplatin, followed by concomitant cisplatin and radiotherapy for the treatment of locally advanced nasopharyngeal carcinoma. J Egypt Natl Canc Inst 2006; 18: 348-56.
4. Gupta AK, McKenna WG, Weber CN et al. Local recurrence in head and neck cancer: relationship to radiation resistance and signal transduction. Clin Cancer Res 2002; 8: 885-92.
5. Gu W, Wang X, Zhai C, Zhou T, Xie X. Biological basis of miRNA action when their targets are located in human protein coding region. PLoS ONE 2013; 8: e63403.
6. Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ. miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res 2006; 34: 140-4.
7. Li T, Lu YY, Zhao XD et al. MicroRNA-296-5p increases proliferation in gastric cancer through repression of Caudal-related homeobox 1. Oncogene 2014; 33: 783-93.
8. Bockhorn J, Yee K, Chang YF et al. MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasion. Breast Cancer Res Treat 2013; 137: 373-82.
9. Bouyssou JM, Manier S, Huynh D, Issa S, Roccaro AM, Ghobrial IM. Regulation of microRNAs in cancer metastasis. Biochim Biophys Acta 2014; 1845: 255-65.
10. Kong W, He L, Richards EJ et al. Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer. Oncogene 2014; 33: 679-89.
11. Tekiner TA, Basaga H. Role of microRNA deregulation in breast cancer cell chemoresistance and stemness. Curr Med Chem 2013; 20: 3358-69.
12. Liu ZL, Wang H, Liu J, Wang ZX. MicroRNA-21 (miR-21) expression promotes growth, metastasis, and chemo- or radioresistance in non-small cell lung cancer cells by targeting PTEN. Mol Cell Biochem 2013; 372: 35-45.
13. Grosso S, Doyen J, Parks SK et al. MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines. Cell Death Dis 2013; 4: e544.
14. Lee KM, Choi EJ, Kim IA. microRNA-7 increases radiosensitivity of human cancer cells with activated EGFR-associated signaling. Radiother Oncol 2011; 101: 171-6.
15. Qu C, Liang Z, Huang J et al. MiR-205 determines the radioresistance of human nasopharyngeal carcinoma by directly targeting PTEN. Cell Cycle 2012; 11: 785-96.
16. Li G, Liu Y, Su Z et al. MicroRNA-324-3p regulates nasopharyngeal carcinoma radioresistance by directly targeting WNT2B. Eur J Cancer 2013; 49: 2596-607.
17. Li G, Qiu Y, Su Z et al. Genome-wide analyses of radioresistance-associated miRNA expression profile in nasopharyngeal carcinoma using next generation deep sequencing. PLoS ONE 2013; 8: e84486.
18. Agrawal R, Tran U, Wessely O. The miR-30 miRNA family regulates Xenopus pronephros development and targets the transcription factor Xlim1/Lhx1. Development 2009; 136: 3927-36.
19. Allen E, Xie Z, Gustafson AM, Carrington JC. microRNA-directed phasing during trans-acting siRNA biogenesis in plants. Cell 2005; 121: 207-21.
20. Schwab R, Palatnik JF, Riester M, Schommer C, Schmid M, Weigel D. Specific effects of microRNAs on the plant transcriptome. Dev Cell 2005; 8: 517-27.
21. Li G, Liu Y, Su ZW et al. Irradiation induced epithelial-mesenchymal transition in nasopharyngeal carcinoma in vitro. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2013; 48: 662-7.
22. Feng XP, Yi H, Li MY et al. Identification of biomarkers for predicting nasopharyngeal carcinoma response to radiotherapy by proteomics. Cancer Res 2010; 70: 3450-62.
23. Liao JM, Lu H. Autoregulatory suppression of c-Myc by miR-185-3p. J Biol Chem 2011; 286: 33901-9.
24. Maussion G, Yang J, Yerko V et al. Regulation of a truncated form of tropomyosin-related kinase B (TrkB) by Hsa-miR-185* in frontal cortex of suicide completers. PLoS ONE 2012; 7: e39301.
25. Zhi Q, Zhu J, Guo X et al. Metastasis-related miR-185 is a potential prognostic biomarker for hepatocellular carcinoma in early stage. Biomed Pharmacother 2013; 67: 393-8.
26. Xiang Y, Ma N, Wang D et al. MiR-152 and miR-185 co-contribute to ovarian cancer cells cisplatin sensitivity by targeting DNMT1 directly: a novel epigenetic therapy independent of decitabine. Oncogene 2014; 33: 378-86.
27. Serafini G, Pompili M, Hansen KF et al. The involvement of microRNAs in major depression, suicidal behavior, and related disorders: a focus on miR-185 and miR-491-3p. Cell Mol Neurobiol 2014; 34: 17-30.
28. Wang J, He J, Su F et al. Repression of ATR pathway by miR-185 enhances radiation-induced apoptosis and proliferation inhibition. Cell Death Dis 2013; 4: e699.
29. Liu D, Kadota K, Ueno M, Nakashima N, Yokomise H, Huang CL. Adenoviral vector expressing short hairpin RNA targeting Wnt2B has an effective antitumour activity against Wnt2B2-overexpressing tumours. Eur J Cancer 2012; 48: 1208-18.
30. Watanabe O, Imamura H, Shimizu T et al. Expression of twist and wnt in human breast cancer. Anticancer Res 2004; 24: 3851-6.
31. Katoh M. Frequent up-regulation of WNT2 in primary gastric cancer and colorectal cancer. Int J Oncol 2001; 19: 1003-7.
32. Wang H, Fan L, Xia X et al. Silencing Wnt2B by siRNA interference inhibits metastasis and enhances chemotherapy sensitivity in ovarian cancer. Int J Gynecol Cancer 2012; 22: 755-61.
33. Kobayashi M, Huang CL, Sonobe M et al. Intratumoral Wnt2B expression affects tumor proliferation and survival in malignant pleural mesothelioma patients. Exp Ther Med 2012; 3: 952-8.
34. Ma G, Yasunaga J, Fan J, Yanagawa S, Matsuoka M. HTLV-1 bZIP factor dysregulates the Wnt pathways to support proliferation and migration of adult T-cell leukemia cells. Oncogene 2013; 32: 4222-30.
35. Teichman J. Hedgehog Signalling and Tumour-Initiating Cells as Radioresistance Factors in Esophageal Adenocarcinoma. University of Toronto, 2012.
36. Singh A, Settleman J. EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene 2010; 29: 4741-51.
37. Chang L, Graham PH, Hao J et al. Acquisition of epithelial-mesenchymal transition and cancer stem cell phenotypes is associated with activation of the PI3K/Akt/mTOR pathway in prostate cancer radioresistance. Cell Death Dis 2013; 4: e875.
38. Zhang JX, Mai SJ, Huang XX et al. MiR-29c mediates epithelial-to-mesenchymal transition in human colorectal carcinoma metastasis via PTP4A and GNA13 regulation of beta-catenin signaling. Ann Oncol 2014; doi:10.1093/annonc/mdu439.
39. Steinway SN, Gomez TZJ, Ding W et al. Network modeling of TGFbeta signaling in hepatocellular carcinoma epithelial-to-mesenchymal transition reveals joint Sonic hedgehog and Wnt pathway activation. Cancer Res 2014. doi:10.1158/0008-5472.CAN-14-0225.
40. Warrier S, Bhuvanalakshmi G, Arfuso F, Rajan G, Millward M, Dharmarajan A. Cancer stem-like cells from head and neck cancers are chemosensitized by the Wnt antagonist, sFRP4, by inducing apoptosis, decreasing stemness, drug resistance and epithelial to mesenchymal transition. Cancer Gene Ther 2014; 21: 381-8.
41. Llave C, Xie Z, Kasschau KD, Carrington JC. Cleavage of Scarecrow-like mRNA targets directed by a class of Arabidopsis miRNA. Science 2002; 297: 2053-6.
42. Lai EC. Predicting and validating microRNA targets. Genome Biol 2004; 5: 115.
43. Duursma AM, Kedde M, Schrier M, le Sage C, Agami R. miR-148 targets human DNMT3b protein coding region. RNA 2008; 14: 872-7.