IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival

Oncotarget

Volumn 5, Issue 22, 2014, Pages 11064-11080

  Lunardi, Serena ^a   Jamieson, Nigel B ^b   Lim, Su Yin ^a   Griffiths, Kristin L ^c   Carvalho Gaspar, Manuela ^a   Al Assar, Osama ^a   Yameen, Sabira ^a   Carter, Ross C ^b   McKay, Colin J ^b   Spoletini, Gabriele ^d   D'Ugo, Stefano ^d   Silva, Michael A ^d   Sansom, Owen J ^e   Janssen, Klaus Peter ^f   Muschel, Ruth J ^a   Brunner, Thomas B ^a,g  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b GLASGOW ROYAL INFIRMARY   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d CHURCHILL HOSPITAL   (United Kingdom)

^e BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^f TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^g UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Cxcl10; IP 10; Pancreatic cancer; Pancreatic stellate cells; Tumor stroma

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CXCR; CXCL1 CHEMOKINE; EOTAXIN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 15; INTERLEUKIN 6; INTERLEUKIN 8; LEUKEMIA INHIBITORY FACTOR; STROMAL CELL DERIVED FACTOR 1ALPHA; CXCL10 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CANCER SURVIVAL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ISOLATION; CELL MIGRATION; CELL VIABILITY; CHEMOTAXIS; CLINICAL ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATIONAL STUDY; CYTOKINE RELEASE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSE; LYMPHOCYTE; OVERALL SURVIVAL; PANCREAS ADENOCARCINOMA; PANCREATIC CANCER CELL LINE; PANCREATIC STELLATE CELL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; STROMA; TUMOR GROWTH; UPREGULATION; BIOSYNTHESIS; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; METABOLISM; PANCREAS CARCINOMA; PANCREAS TUMOR; PATHOLOGY; STROMA CELL; SURVIVAL; TUMOR CELL LINE;

CARCINOMA, PANCREATIC DUCTAL; CELL LINE, TUMOR; CHEMOKINE CXCL10; HEK293 CELLS; HUMANS; PANCREATIC NEOPLASMS; PANCREATIC STELLATE CELLS; STROMAL CELLS; SURVIVAL ANALYSIS; T-LYMPHOCYTES, REGULATORY;

EID: 84917690504     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2519     Document Type: Article

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