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Volumn 36, Issue 1, 2015, Pages 7-17

The transcription factor Nrf2 is decreased after spontaneous term labour in human fetal membranes where it exerts anti-inflammatory properties

Author keywords

Fetal membranes; Human labour; Inflammation; Nrf2

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; NUCLEAR PROTEIN; POLYINOSINIC POLYCYTIDYLIC ACID; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 5; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; NFE2L2 PROTEIN, HUMAN; SMALL INTERFERING RNA;

EID: 84916894758     PISSN: 01434004     EISSN: 15323102     Source Type: Journal    
DOI: 10.1016/j.placenta.2014.11.004     Document Type: Article
Times cited : (25)

References (62)
  • 1
    • 77953002425 scopus 로고    scopus 로고
    • Global, regional, and national causes of child mortality in 2008: A systematic analysis
    • R.E. Black, S. Cousens, H.L. Johnson, J.E. Lawn, I. Rudan, and D.G. Bassani Global, regional, and national causes of child mortality in 2008: a systematic analysis Lancet 375 9730 2010 1969 1987
    • (2010) Lancet , vol.375 , Issue.9730 , pp. 1969-1987
    • Black, R.E.1    Cousens, S.2    Johnson, H.L.3    Lawn, J.E.4    Rudan, I.5    Bassani, D.G.6
  • 2
    • 14744298742 scopus 로고    scopus 로고
    • 4 million neonatal deaths: When? Where? Why?
    • Lawn JE, Cousens S and Zupan J. 4 million neonatal deaths: when? Where? Why? Lancet 365(9462):891-900.
    • Lancet , vol.365 , Issue.9462 , pp. 891-900
    • Lawn, J.E.1    Cousens, S.2    Zupan, J.3
  • 3
    • 38149116341 scopus 로고    scopus 로고
    • An overview of mortality and sequelae of preterm birth from infancy to adulthood
    • S. Saigal, and L.W. Doyle An overview of mortality and sequelae of preterm birth from infancy to adulthood Lancet 371 9608 2008 261 269
    • (2008) Lancet , vol.371 , Issue.9608 , pp. 261-269
    • Saigal, S.1    Doyle, L.W.2
  • 4
    • 79953029070 scopus 로고    scopus 로고
    • Impact of histological chorioamnionitis, funisitis and clinical chorioamnionitis on neurodevelopmental outcome of preterm infants
    • N. Rovira, A. Alarcon, M. Iriondo, M. Ibanez, P. Poo, and V. Cusi Impact of histological chorioamnionitis, funisitis and clinical chorioamnionitis on neurodevelopmental outcome of preterm infants Early Hum Dev 87 4 2011 253 257
    • (2011) Early Hum Dev , vol.87 , Issue.4 , pp. 253-257
    • Rovira, N.1    Alarcon, A.2    Iriondo, M.3    Ibanez, M.4    Poo, P.5    Cusi, V.6
  • 5
    • 14644400434 scopus 로고    scopus 로고
    • The economic consequences of preterm birth during the first 10 years of life
    • S. Petrou The economic consequences of preterm birth during the first 10 years of life Bjog Int J Obstet Gynecol 112 2005 10 15
    • (2005) Bjog Int J Obstet Gynecol , vol.112 , pp. 10-15
    • Petrou, S.1
  • 6
    • 84907191224 scopus 로고    scopus 로고
    • Measuring economic consequences of preterm birth - Methodological recommendations for the evaluation of personal burden on children and their caregivers
    • J.M. Hodek, T. Mittendorf, and M.G. Von der Schulenburg Measuring economic consequences of preterm birth - methodological recommendations for the evaluation of personal burden on children and their caregivers Acta Paediatr 99 2010 98
    • (2010) Acta Paediatr , vol.99 , pp. 98
    • Hodek, J.M.1    Mittendorf, T.2    Von Der Schulenburg, M.G.3
  • 7
    • 0032485450 scopus 로고    scopus 로고
    • Mechanisms of disease - Premature rupture of the fetal membranes
    • S. Parry, and J.F. Strauss Mechanisms of disease - premature rupture of the fetal membranes N Engl J Med 338 10 1998 663 670
    • (1998) N Engl J Med , vol.338 , Issue.10 , pp. 663-670
    • Parry, S.1    Strauss, J.F.2
  • 8
    • 33748741185 scopus 로고    scopus 로고
    • The physiology of fetal membrane rupture: Insight gained from the determination of physical properties
    • R.M. Moore, J.M. Mansour, R.W. Redline, B.M. Mercer, and J.J. Moore The physiology of fetal membrane rupture: insight gained from the determination of physical properties Placenta 27 11-12 2006 1037 1051
    • (2006) Placenta , vol.27 , Issue.1112 , pp. 1037-1051
    • Moore, R.M.1    Mansour, J.M.2    Redline, R.W.3    Mercer, B.M.4    Moore, J.J.5
  • 9
    • 0036549899 scopus 로고    scopus 로고
    • Cytokines of the placenta and extra-placental membranes: Roles and regulation during human pregnancy and parturition
    • J.M. Bowen, L. Chamley, J.A. Keelan, and M.D. Mitchell Cytokines of the placenta and extra-placental membranes: roles and regulation during human pregnancy and parturition Placenta 23 4 2002 257 273
    • (2002) Placenta , vol.23 , Issue.4 , pp. 257-273
    • Bowen, J.M.1    Chamley, L.2    Keelan, J.A.3    Mitchell, M.D.4
  • 10
    • 0031727198 scopus 로고    scopus 로고
    • A role for matrix metalloproteinase-9 in spontaneous rupture of the fetal membranes
    • N. Athayde, S.S. Edwin, R. Romero, R. Gomez, E. Maymon, and P. Pacora A role for matrix metalloproteinase-9 in spontaneous rupture of the fetal membranes Am J Obstet Gynecol 179 5 1998 1248 1253
    • (1998) Am J Obstet Gynecol , vol.179 , Issue.5 , pp. 1248-1253
    • Athayde, N.1    Edwin, S.S.2    Romero, R.3    Gomez, R.4    Maymon, E.5    Pacora, P.6
  • 12
    • 11444261268 scopus 로고    scopus 로고
    • Gene expression profiling of NRF2-mediated protection against oxidative injury
    • H.Y. Cho, S.P. Reddy, A. Debiase, M. Yamamoto, and S.R. Kleeberger Gene expression profiling of NRF2-mediated protection against oxidative injury Free Radic Biol Med 38 3 2005 325 343
    • (2005) Free Radic Biol Med , vol.38 , Issue.3 , pp. 325-343
    • Cho, H.Y.1    Reddy, S.P.2    Debiase, A.3    Yamamoto, M.4    Kleeberger, S.R.5
  • 13
    • 0037106099 scopus 로고    scopus 로고
    • Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray
    • R.K. Thimmulappa, K.H. Mai, S. Srisuma, T.W. Kensler, M. Yamamoto, and S. Biswal Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray Cancer Res 62 18 2002 5196 5203
    • (2002) Cancer Res , vol.62 , Issue.18 , pp. 5196-5203
    • Thimmulappa, R.K.1    Mai, K.H.2    Srisuma, S.3    Kensler, T.W.4    Yamamoto, M.5    Biswal, S.6
  • 14
    • 54449093079 scopus 로고    scopus 로고
    • Dysfunction of Nrf-2 in CF epithelia leads to excess intracellular H2O2 and inflammatory cytokine production
    • J. Chen, M. Kinter, S. Shank, C. Cotton, T.J. Kelley, and A.G. Ziady Dysfunction of Nrf-2 in CF epithelia leads to excess intracellular H2O2 and inflammatory cytokine production PloS One 3 10 2008 e3367
    • (2008) PloS One , vol.3 , Issue.10 , pp. 3367
    • Chen, J.1    Kinter, M.2    Shank, S.3    Cotton, C.4    Kelley, T.J.5    Ziady, A.G.6
  • 15
    • 84867299016 scopus 로고    scopus 로고
    • Gene expression profiling following NRF2 and KEAP1 siRNA knockdown in human lung fibroblasts identifies CCL11/eotaxin-1 as a novel NRF2 regulated gene
    • J. Fourtounis, I.M. Wang, M.C. Mathieu, D. Claveau, T. Loo, and A.L. Jackson Gene expression profiling following NRF2 and KEAP1 siRNA knockdown in human lung fibroblasts identifies CCL11/eotaxin-1 as a novel NRF2 regulated gene Respir Res 13 2012 92
    • (2012) Respir Res , vol.13 , pp. 92
    • Fourtounis, J.1    Wang, I.M.2    Mathieu, M.C.3    Claveau, D.4    Loo, T.5    Jackson, A.L.6
  • 16
    • 70449723401 scopus 로고    scopus 로고
    • Innate immunity against bacterial infection following hyperoxia exposure is impaired in NRF2-deficient mice
    • N.M. Reddy, V. Suryanarayana, D.V. Kalvakolanu, M. Yamamoto, T.W. Kensler, and P.M. Hassoun Innate immunity against bacterial infection following hyperoxia exposure is impaired in NRF2-deficient mice J Immunol 183 7 2009 4601 4608
    • (2009) J Immunol , vol.183 , Issue.7 , pp. 4601-4608
    • Reddy, N.M.1    Suryanarayana, V.2    Kalvakolanu, D.V.3    Yamamoto, M.4    Kensler, T.W.5    Hassoun, P.M.6
  • 17
    • 79960549767 scopus 로고    scopus 로고
    • TNF mediates the sustained activation of Nrf2 in human monocytes
    • S.A. Rushworth, S. Shah, and D.J. MacEwan TNF mediates the sustained activation of Nrf2 in human monocytes J Immunol 187 2 2011 702 707
    • (2011) J Immunol , vol.187 , Issue.2 , pp. 702-707
    • Rushworth, S.A.1    Shah, S.2    Macewan, D.J.3
  • 18
    • 84888162122 scopus 로고    scopus 로고
    • MafK positively regulates NF-kappaB activity by enhancing CBP-mediated p65 acetylation
    • Y.J. Hwang, E.W. Lee, J. Song, H.R. Kim, Y.C. Jun, and K.A. Hwang MafK positively regulates NF-kappaB activity by enhancing CBP-mediated p65 acetylation Sci Rep 3 2013 3242
    • (2013) Sci Rep , vol.3 , pp. 3242
    • Hwang, Y.J.1    Lee, E.W.2    Song, J.3    Kim, H.R.4    Jun, Y.C.5    Hwang, K.A.6
  • 19
    • 82355183968 scopus 로고    scopus 로고
    • A defect in Nrf2 signaling constitutes a mechanism for cellular stress hypersensitivity in a genetic rat model of type 2 diabetes
    • M.S. Bitar, and F. Al-Mulla A defect in Nrf2 signaling constitutes a mechanism for cellular stress hypersensitivity in a genetic rat model of type 2 diabetes Am J Physiol Endocrinol Metab 301 6 2011 E1119 E1129
    • (2011) Am J Physiol Endocrinol Metab , vol.301 , Issue.6 , pp. 1119-E1129
    • Bitar, M.S.1    Al-Mulla, F.2
  • 20
    • 84875364553 scopus 로고    scopus 로고
    • Redox-sensitive transcription factor Nrf2 regulates vascular smooth muscle cell migration and neointimal hyperplasia
    • T. Ashino, M. Yamamoto, T. Yoshida, and S. Numazawa Redox-sensitive transcription factor Nrf2 regulates vascular smooth muscle cell migration and neointimal hyperplasia Arterioscler Thromb Vasc Biol 33 4 2013 760 768
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , Issue.4 , pp. 760-768
    • Ashino, T.1    Yamamoto, M.2    Yoshida, T.3    Numazawa, S.4
  • 21
    • 84867280729 scopus 로고    scopus 로고
    • Decreased lectin-like oxidized LDL receptor 1 (LOX-1) and low Nrf2 activation in placenta are involved in preeclampsia
    • Y. Chigusa, K. Tatsumi, E. Kondoh, K. Fujita, F. Nishimura, and H. Mogami Decreased lectin-like oxidized LDL receptor 1 (LOX-1) and low Nrf2 activation in placenta are involved in preeclampsia J Clin Endocrinol Metab 97 10 2012 E1862 E1870
    • (2012) J Clin Endocrinol Metab , vol.97 , Issue.10 , pp. 1862-E1870
    • Chigusa, Y.1    Tatsumi, K.2    Kondoh, E.3    Fujita, K.4    Nishimura, F.5    Mogami, H.6
  • 22
    • 84891820074 scopus 로고    scopus 로고
    • Gestational diabetes mellitus impairs Nrf2-mediated adaptive antioxidant defenses and redox signaling in fetal endothelial cells in utero
    • X. Cheng, S.J. Chapple, B. Patel, W. Puszyk, D. Sugden, and X. Yin Gestational diabetes mellitus impairs Nrf2-mediated adaptive antioxidant defenses and redox signaling in fetal endothelial cells in utero Diabetes 62 12 2013 4088 4097
    • (2013) Diabetes , vol.62 , Issue.12 , pp. 4088-4097
    • Cheng, X.1    Chapple, S.J.2    Patel, B.3    Puszyk, W.4    Sugden, D.5    Yin, X.6
  • 24
    • 67649213186 scopus 로고    scopus 로고
    • Increased expression of ac-FoxO1 protein in prelabor fetal membranes overlying the cervix: Possible role in human fetal membrane rupture
    • M. Lappas, C. Riley, G.E. Rice, and M. Permezel Increased expression of ac-FoxO1 protein in prelabor fetal membranes overlying the cervix: possible role in human fetal membrane rupture Reprod Sci 16 7 2009 635 641
    • (2009) Reprod Sci , vol.16 , Issue.7 , pp. 635-641
    • Lappas, M.1    Riley, C.2    Rice, G.E.3    Permezel, M.4
  • 26
    • 84924543243 scopus 로고    scopus 로고
    • Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are increased after labour in foetal membranes and myometrium and are essential for TNF-alpha-induced expression of pro-labour mediators
    • M. Lappas Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are increased after labour in foetal membranes and myometrium and are essential for TNF-alpha-induced expression of pro-labour mediators Am J Reprod Immunol 2014 Jul 21 10.1111/aji.12295 PMID:25046208
    • (2014) Am J Reprod Immunol
    • Lappas, M.1
  • 27
    • 84655167217 scopus 로고    scopus 로고
    • Human labour is associated with decreased cytoplasmic FoxO4
    • R. Lim, C. Riley, G. Barker, G.E. Rice, and M. Lappas Human labour is associated with decreased cytoplasmic FoxO4 Placenta 33 1 2012 52 59
    • (2012) Placenta , vol.33 , Issue.1 , pp. 52-59
    • Lim, R.1    Riley, C.2    Barker, G.3    Rice, G.E.4    Lappas, M.5
  • 28
    • 84877066538 scopus 로고    scopus 로고
    • SIRT6 is decreased with preterm labor and regulates key terminal effector pathways of human labor in fetal membranes
    • R. Lim, G. Barker, and M. Lappas SIRT6 is decreased with preterm labor and regulates key terminal effector pathways of human labor in fetal membranes Biol Reprod 88 1 2013 17
    • (2013) Biol Reprod , vol.88 , Issue.1 , pp. 17
    • Lim, R.1    Barker, G.2    Lappas, M.3
  • 29
    • 84889048698 scopus 로고    scopus 로고
    • NOD1 and NOD2 regulate proinflammatory and prolabor mediators in human fetal membranes and myometrium via nuclear factor-kappa B
    • M. Lappas NOD1 and NOD2 regulate proinflammatory and prolabor mediators in human fetal membranes and myometrium via nuclear factor-kappa B Biol Reprod 89 1 2013 14
    • (2013) Biol Reprod , vol.89 , Issue.1 , pp. 14
    • Lappas, M.1
  • 30
    • 68949206603 scopus 로고    scopus 로고
    • Preterm and infection-driven preterm labor: The role of peroxisome proliferator-activated receptors and retinoid X receptor
    • S.J. Holdsworth-Carson, M. Permezel, G.E. Rice, and M. Lappas Preterm and infection-driven preterm labor: the role of peroxisome proliferator-activated receptors and retinoid X receptor Reproduction 137 6 2009 1007 1015
    • (2009) Reproduction , vol.137 , Issue.6 , pp. 1007-1015
    • Holdsworth-Carson, S.J.1    Permezel, M.2    Rice, G.E.3    Lappas, M.4
  • 31
    • 58049182737 scopus 로고    scopus 로고
    • Term labor is associated with a core inflammatory response in human fetal membranes, myometrium, and cervix
    • e1-11
    • S. Bollapragada, R. Youssef, F. Jordan, I. Greer, J. Norman, and S. Nelson Term labor is associated with a core inflammatory response in human fetal membranes, myometrium, and cervix Am J Obstet Gynecol 200 1 2009 104 e1 11
    • (2009) Am J Obstet Gynecol , vol.200 , Issue.1 , pp. 104
    • Bollapragada, S.1    Youssef, R.2    Jordan, F.3    Greer, I.4    Norman, J.5    Nelson, S.6
  • 32
    • 0037215931 scopus 로고    scopus 로고
    • Leukocyte density and pro-inflammatory cytokine expression in human fetal membranes, decidua, cervix and myometrium before and during labour at term
    • I. Osman, A. Young, M.A. Ledingham, A.J. Thomson, F. Jordan, and I.A. Greer Leukocyte density and pro-inflammatory cytokine expression in human fetal membranes, decidua, cervix and myometrium before and during labour at term Mol Hum Reprod 9 1 2003 41 45
    • (2003) Mol Hum Reprod , vol.9 , Issue.1 , pp. 41-45
    • Osman, I.1    Young, A.2    Ledingham, M.A.3    Thomson, A.J.4    Jordan, F.5    Greer, I.A.6
  • 35
    • 56549119526 scopus 로고    scopus 로고
    • Pre-labour fetal membranes overlying the cervix display alterations in inflammation and NF-kappaB signalling pathways
    • M. Lappas, T.L. Odumetse, C. Riley, N.G. Reti, S.J. Holdsworth-Carson, and G.E. Rice Pre-labour fetal membranes overlying the cervix display alterations in inflammation and NF-kappaB signalling pathways Placenta 29 12 2008 995 1002
    • (2008) Placenta , vol.29 , Issue.12 , pp. 995-1002
    • Lappas, M.1    Odumetse, T.L.2    Riley, C.3    Reti, N.G.4    Holdsworth-Carson, S.J.5    Rice, G.E.6
  • 36
    • 34247205826 scopus 로고    scopus 로고
    • Why do membranes rupture at term? Evidence of increased cellular apoptosis in the supracervical fetal membranes
    • e1-10
    • N.G. Reti, M. Lappas, C. Riley, M.E. Wlodek, M. Permezel, and S. Walker Why do membranes rupture at term? Evidence of increased cellular apoptosis in the supracervical fetal membranes Am J Obstet Gynecol 196 5 2007 484 e1 10
    • (2007) Am J Obstet Gynecol , vol.196 , Issue.5 , pp. 484
    • Reti, N.G.1    Lappas, M.2    Riley, C.3    Wlodek, M.E.4    Permezel, M.5    Walker, S.6
  • 37
    • 30344435023 scopus 로고    scopus 로고
    • Proinflammatory cytokines found in amniotic fluid induce collagen remodeling, apoptosis, and biophysical weakening of cultured human fetal membranes
    • D. Kumar, W. Fung, R.M. Moore, V. Pandey, J. Fox, and B. Stetzer Proinflammatory cytokines found in amniotic fluid induce collagen remodeling, apoptosis, and biophysical weakening of cultured human fetal membranes Biol Reprod 74 1 2006 29 34
    • (2006) Biol Reprod , vol.74 , Issue.1 , pp. 29-34
    • Kumar, D.1    Fung, W.2    Moore, R.M.3    Pandey, V.4    Fox, J.5    Stetzer, B.6
  • 38
    • 27844554853 scopus 로고    scopus 로고
    • The role of nuclear factor kappa B in human labour
    • T.M. Lindstrom, and P.R. Bennett The role of nuclear factor kappa B in human labour Reproduction 130 5 2005 569 581
    • (2005) Reproduction , vol.130 , Issue.5 , pp. 569-581
    • Lindstrom, T.M.1    Bennett, P.R.2
  • 40
    • 0032738714 scopus 로고    scopus 로고
    • The tumor necrosis factor alpha and its soluble receptor profile in term and preterm parturition
    • E. Maymon, F. Ghezzi, S.S. Edwin, M. Mazor, B.H. Yoon, and R. Gomez The tumor necrosis factor alpha and its soluble receptor profile in term and preterm parturition Am J Obstet Gynecol 181 5 Pt 1 1999 1142 1148
    • (1999) Am J Obstet Gynecol , vol.181 , Issue.5 PART 1 , pp. 1142-1148
    • Maymon, E.1    Ghezzi, F.2    Edwin, S.S.3    Mazor, M.4    Yoon, B.H.5    Gomez, R.6
  • 41
    • 0034682251 scopus 로고    scopus 로고
    • Intrauterine infection and preterm delivery
    • R.L. Goldenberg, J.C. Hauth, and W.W. Andrews Intrauterine infection and preterm delivery N Engl J Med 342 20 2000 1500 1507
    • (2000) N Engl J Med , vol.342 , Issue.20 , pp. 1500-1507
    • Goldenberg, R.L.1    Hauth, J.C.2    Andrews, W.W.3
  • 42
    • 0024564252 scopus 로고
    • Cachectin/tumor necrosis factor-alpha formation in human decidua. Potential role of cytokines in infection-induced preterm labor
    • M.L. Casey, S.M. Cox, B. Beutler, L. Milewich, and P.C. MacDonald Cachectin/tumor necrosis factor-alpha formation in human decidua. Potential role of cytokines in infection-induced preterm labor J Clin Investig 83 2 1989 430 436
    • (1989) J Clin Investig , vol.83 , Issue.2 , pp. 430-436
    • Casey, M.L.1    Cox, S.M.2    Beutler, B.3    Milewich, L.4    Macdonald, P.C.5
  • 43
    • 0038325598 scopus 로고    scopus 로고
    • Infection in the prediction and antibiotics in the prevention of spontaneous preterm labour and preterm birth
    • R.F. Lamont Infection in the prediction and antibiotics in the prevention of spontaneous preterm labour and preterm birth BJOG Int J Obstet Gynaecol 110 Suppl. 20 2003 71 75
    • (2003) BJOG Int J Obstet Gynaecol , vol.110 , pp. 71-75
    • Lamont, R.F.1
  • 44
    • 58349086149 scopus 로고    scopus 로고
    • Maternal versus fetal inflammation and respiratory distress syndrome: A 10-year hospital cohort study
    • M.M. Lahra, P.J. Beeby, and H.E. Jeffery Maternal versus fetal inflammation and respiratory distress syndrome: a 10-year hospital cohort study Arch Dis Child Fetal Neonatal Ed 94 1 2009 F13 F16
    • (2009) Arch Dis Child Fetal Neonatal Ed , vol.94 , Issue.1 , pp. 13-F16
    • Lahra, M.M.1    Beeby, P.J.2    Jeffery, H.E.3
  • 45
    • 0742269643 scopus 로고    scopus 로고
    • A fetal response to chorioamnionitis is associated with early survival after preterm birth
    • M.M. Lahra, and H.E. Jeffery A fetal response to chorioamnionitis is associated with early survival after preterm birth Am J Obstet Gynecol 190 1 2004 147 151
    • (2004) Am J Obstet Gynecol , vol.190 , Issue.1 , pp. 147-151
    • Lahra, M.M.1    Jeffery, H.E.2
  • 46
    • 0142244180 scopus 로고    scopus 로고
    • A new model for inflammation-induced preterm birth: The role of platelet-activating factor and Toll-like receptor-4
    • M.A. Elovitz, Z. Wang, E.K. Chien, D.F. Rychlik, and M. Phillippe A new model for inflammation-induced preterm birth: the role of platelet-activating factor and Toll-like receptor-4 Am J Pathol 163 5 2003 2103 2111
    • (2003) Am J Pathol , vol.163 , Issue.5 , pp. 2103-2111
    • Elovitz, M.A.1    Wang, Z.2    Chien, E.K.3    Rychlik, D.F.4    Phillippe, M.5
  • 48
    • 84898812077 scopus 로고    scopus 로고
    • The TLR2 ligand FSL-1 and the TLR5 ligand flagellin mediate pro-inflammatory and pro-labour response via MyD88/TRAF6/NF-kappaB-dependent signalling
    • R. Lim, G. Barker, and M. Lappas The TLR2 ligand FSL-1 and the TLR5 ligand flagellin mediate pro-inflammatory and pro-labour response via MyD88/TRAF6/NF-kappaB-dependent signalling Am J Reprod Immunol N Y 1989 71 5 2014 401 417
    • (2014) Am J Reprod Immunol N y 1989 , vol.71 , Issue.5 , pp. 401-417
    • Lim, R.1    Barker, G.2    Lappas, M.3
  • 49
    • 80052677599 scopus 로고    scopus 로고
    • Functional screening of TLRs in human amniotic epithelial cells
    • C. Gillaux, C. Mehats, D. Vaiman, D. Cabrol, and M. Breuiller-Fouche Functional screening of TLRs in human amniotic epithelial cells J Immunol 187 5 2011 2766 2774
    • (2011) J Immunol , vol.187 , Issue.5 , pp. 2766-2774
    • Gillaux, C.1    Mehats, C.2    Vaiman, D.3    Cabrol, D.4    Breuiller-Fouche, M.5
  • 50
    • 33645530745 scopus 로고    scopus 로고
    • Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis
    • R.K. Thimmulappa, H. Lee, T. Rangasamy, S.P. Reddy, M. Yamamoto, and T.W. Kensler Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis J Clin Investig 116 4 2006 984 995
    • (2006) J Clin Investig , vol.116 , Issue.4 , pp. 984-995
    • Thimmulappa, R.K.1    Lee, H.2    Rangasamy, T.3    Reddy, S.P.4    Yamamoto, M.5    Kensler, T.W.6
  • 51
    • 52949139019 scopus 로고    scopus 로고
    • Sulforaphane suppressed LPS-induced inflammation in mouse peritoneal macrophages through Nrf2 dependent pathway
    • W. Lin, R.T. Wu, T. Wu, T.O. Khor, H. Wang, and A.N. Kong Sulforaphane suppressed LPS-induced inflammation in mouse peritoneal macrophages through Nrf2 dependent pathway Biochem Pharmacol 76 8 2008 967 973
    • (2008) Biochem Pharmacol , vol.76 , Issue.8 , pp. 967-973
    • Lin, W.1    Wu, R.T.2    Wu, T.3    Khor, T.O.4    Wang, H.5    Kong, A.N.6
  • 52
    • 40749121296 scopus 로고    scopus 로고
    • Placental infection with human papillomavirus is associated with spontaneous preterm delivery
    • L.M. Gomez, Y. Ma, C. Ho, C.M. McGrath, D.B. Nelson, and S. Parry Placental infection with human papillomavirus is associated with spontaneous preterm delivery Hum Reprod 23 3 2008 709 715
    • (2008) Hum Reprod , vol.23 , Issue.3 , pp. 709-715
    • Gomez, L.M.1    Ma, Y.2    Ho, C.3    McGrath, C.M.4    Nelson, D.B.5    Parry, S.6
  • 53
  • 54
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
    • L. Alexopoulou, A.C. Holt, R. Medzhitov, and R.A. Flavell Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3 Nature 413 6857 2001 732 738
    • (2001) Nature , vol.413 , Issue.6857 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 55
    • 84903763588 scopus 로고    scopus 로고
    • Single- and double-stranded viral RNA generate distinct cytokine and antiviral responses in human fetal membranes
    • S.L. Bakaysa, J.A. Potter, M. Hoang, C.S. Han, S. Guller, and E.R. Norwitz Single- and double-stranded viral RNA generate distinct cytokine and antiviral responses in human fetal membranes Mol Hum Reprod 20 7 2014 701 708
    • (2014) Mol Hum Reprod , vol.20 , Issue.7 , pp. 701-708
    • Bakaysa, S.L.1    Potter, J.A.2    Hoang, M.3    Han, C.S.4    Guller, S.5    Norwitz, E.R.6
  • 57
    • 79955371606 scopus 로고    scopus 로고
    • Role of Nrf2 in host defense against influenza virus in cigarette smoke-exposed mice
    • Y. Yageta, Y. Ishii, Y. Morishima, H. Masuko, S. Ano, and T. Yamadori Role of Nrf2 in host defense against influenza virus in cigarette smoke-exposed mice J Virol 85 10 2011 4679 4690
    • (2011) J Virol , vol.85 , Issue.10 , pp. 4679-4690
    • Yageta, Y.1    Ishii, Y.2    Morishima, Y.3    Masuko, H.4    Ano, S.5    Yamadori, T.6
  • 58
    • 0028023597 scopus 로고
    • Antioxidant response element
    • A.K. Jaiswal Antioxidant response element Biochem Pharmacol 48 3 1994 439 444
    • (1994) Biochem Pharmacol , vol.48 , Issue.3 , pp. 439-444
    • Jaiswal, A.K.1
  • 59
    • 77953290236 scopus 로고    scopus 로고
    • Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver
    • N.R. Kitteringham, A. Abdullah, J. Walsh, L. Randle, R.E. Jenkins, and R. Sison Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver J Proteomics 73 8 2010 1612 1631
    • (2010) J Proteomics , vol.73 , Issue.8 , pp. 1612-1631
    • Kitteringham, N.R.1    Abdullah, A.2    Walsh, J.3    Randle, L.4    Jenkins, R.E.5    Sison, R.6
  • 60
    • 84874051303 scopus 로고    scopus 로고
    • Therapeutic effect of MG-132 on diabetic cardiomyopathy is associated with its suppression of proteasomal activities: Roles of Nrf2 and NF-kappaB
    • Y. Wang, W. Sun, B. Du, X. Miao, Y. Bai, and Y. Xin Therapeutic effect of MG-132 on diabetic cardiomyopathy is associated with its suppression of proteasomal activities: roles of Nrf2 and NF-kappaB Am J Physiol Heart Circ Physiol 304 4 2013 H567 H578
    • (2013) Am J Physiol Heart Circ Physiol , vol.304 , Issue.4 , pp. 567-H578
    • Wang, Y.1    Sun, W.2    Du, B.3    Miao, X.4    Bai, Y.5    Xin, Y.6
  • 62
    • 84890441806 scopus 로고    scopus 로고
    • Nrf2 knockout enhances intestinal tumorigenesis in Apc(min/+) mice due to attenuation of anti-oxidative stress pathway while potentiates inflammation
    • K.L. Cheung, J.H. Lee, T.O. Khor, T.Y. Wu, G.X. Li, and J. Chan Nrf2 knockout enhances intestinal tumorigenesis in Apc(min/+) mice due to attenuation of anti-oxidative stress pathway while potentiates inflammation Mol Carcinog 53 1 2014 77 84
    • (2014) Mol Carcinog , vol.53 , Issue.1 , pp. 77-84
    • Cheung, K.L.1    Lee, J.H.2    Khor, T.O.3    Wu, T.Y.4    Li, G.X.5    Chan, J.6


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