Inhibition of NADPH oxidase-1 preserves beta cell function

Diabetologia

Volumn 58, Issue 1, 2015, Pages 113-121

  Weaver, Jessica R ^a   Grzesik, Wojciech ^a   Taylor Fishwick, David A ^a  

^a EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Beta cells; Cytokines; Diabetes; Inflammation; ML171; NADPH oxidase 1

Indexed keywords

CASPASE 3; CYTOKINE; GAMMA INTERFERON; GLUCOSE; INSULIN; INTERLEUKIN 1BETA; ML 171; OXIDOREDUCTASE INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 2-ACETYLPHENOTHIAZINE; ENZYME INHIBITOR; OXIDOREDUCTASE; PHENOTHIAZINE DERIVATIVE; TNF PROTEIN, HUMAN; TUMOR NECROSIS FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL TYPE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ENZYME INHIBITION; FEEDBACK SYSTEM; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; HUMAN; HUMAN CELL; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PROTEIN FUNCTION; PROTEIN INDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; CELL PROTECTION; DRUG EFFECTS; INFLAMMATION; MALE; MOUSE; PHYSIOLOGY; RAT;

ANIMALS; CELLS, CULTURED; CYTOPROTECTION; ENZYME INHIBITORS; HUMANS; INFLAMMATION; INSULIN-SECRETING CELLS; INTERFERON-GAMMA; INTERLEUKIN-1BETA; MALE; MICE; MICE, INBRED C57BL; NADH, NADPH OXIDOREDUCTASES; PHENOTHIAZINES; RATS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84916634541     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-014-3398-2     Document Type: Article

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