Cloning and expression of porcine β1,4 N-acetylgalactosaminyl transferase encoding a new xenoreactive antigen

Xenotransplantation

Volumn 21, Issue 6, 2014, Pages 543-554

  Byrne, Guerard W ^a,b   Du, Zeji ^a   Stalboerger, Paul ^a   Kogelberg, Heide ^b   McGregor, Christopher G A ^a,b  

^a MAYO CLINIC   (United States)

^b Institute of Cardiovascular Medicine and Science (ICMS)   (United Kingdom)

Author keywords

antigen; B4GALNT2; cardiac xenotransplantation; immune response; porcine

Indexed keywords

ANTIGEN; BETA 1,4 N ACETYLGALACTOSAMINYL TRANSFERASE; COMPLEMENTARY DNA; DECAY ACCELERATING FACTOR; GLYCAN; N ACETYLGALACTOSAMINYLTRANSFERASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ANTIBODY; BETA-1,4-N-ACETYL-GALACTOSAMINYL TRANSFERASE 2;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN BINDING; ARTICLE; B4GALNT2 GENE; BACTERIAL ARTIFICIAL CHROMOSOME; COMPLEMENT MEDIATED LYSIS; CONTROLLED STUDY; CYTOLYSIS; DOLICHOS; DOLICHOS BIFLORUS; ENDOTHELIUM CELL; ENZYME ACTIVITY; EXON; FLOW CYTOMETRY; GENE EXPRESSION; GENE LOCUS; GENE PRODUCT; GENE SEQUENCE; GENETIC TRANSFECTION; GRAFT RECIPIENT; HEART TRANSPLANTATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INTRON; MOLECULAR CLONING; MOLECULAR LIBRARY; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; POLYMERASE CHAIN REACTION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SWINE; ANIMAL; BABOON; CELL CULTURE; CELL LINE; CLONING; GENETICS; GRAFT REJECTION; IMMUNOLOGY; PIG; PROCEDURES; TRANSGENIC ANIMAL; XENOGRAFT;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIBODIES; CELL LINE; CELLS, CULTURED; CLONING, ORGANISM; GRAFT REJECTION; HUMANS; N-ACETYLGALACTOSAMINYLTRANSFERASES; PAPIO; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 84916630880     PISSN: 0908665X     EISSN: 13993089     Source Type: Journal    
DOI: 10.1111/xen.12124     Document Type: Article

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