Anti-angiogenic effect of tanshinone IIA involves inhibition of the VEGF/VEGFR2 pathway in vascular endothelial cells

Oncology Reports

Volumn 33, Issue 1, 2015, Pages 163-170

  Xing, Yingying ^a   Tu, Jiajie ^a   Zheng, Lufeng ^a   Guo, Le ^a   Xi, Tao ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Angiogenesis; Human umbilical vascular endothelial cells; Kinase insert domain receptor; Tanshinone IIA

Indexed keywords

CD14 ANTIGEN; GELATINASE A; GELATINASE B; TANSHINONE IIA; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; ABIETANE DERIVATIVE; ANGIOGENESIS INHIBITOR; CD146 ANTIGEN; MCAM PROTEIN, HUMAN; MMP2 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN; TANSHINONE; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2, HUMAN; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; CHORIOALLANTOIS; CONTROLLED STUDY; DOWN REGULATION; EX VIVO STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR RING; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; AORTA; CELL SURVIVAL; CHICK EMBRYO; DRUG EFFECTS; GENE EXPRESSION; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TISSUE CULTURE TECHNIQUE; VASCULARIZATION;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTIGENS, CD146; AORTA; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CHICK EMBRYO; CHORIOALLANTOIC MEMBRANE; DITERPENES, ABIETANE; GENE EXPRESSION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TISSUE CULTURE TECHNIQUES; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84916222799     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2014.3592     Document Type: Article

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