메뉴 건너뛰기




Volumn 190, Issue 11, 2014, Pages 1301-1310

Optogenetic stimulation of adrenergic C1 neurons causes sleep state-dependent cardiorespiratory stimulation and arousal with sighs in rats

Author keywords

EEG; Hypoxia; Medulla oblongata; Respiration; Rostral ventrolateral medulla

Indexed keywords

ADRENERGIC NERVE CELL; ANIMAL; ANOXIA; AROUSAL; BLOOD PRESSURE; BREATHING; CHEMORECEPTOR CELL; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; FEMALE; MALE; MEDULLA OBLONGATA; OPTOGENETICS; PHYSIOLOGY; PROCEDURES; RAT; SLEEP; TACHYPNEA;

EID: 84916197420     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201407-1262OC     Document Type: Article
Times cited : (76)

References (59)
  • 4
    • 84870410255 scopus 로고    scopus 로고
    • Role of central/peripheral chemoreceptors and their interdependence in the pathophysiology of sleep apnea
    • Dempsey JA, Smith CA, Blain GM, Xie A, Gong Y, Teodorescu M. Role of central/peripheral chemoreceptors and their interdependence in the pathophysiology of sleep apnea. Adv Exp Med Biol 2012;758:343-349.
    • (2012) Adv Exp Med Biol , vol.758 , pp. 343-349
    • Dempsey, J.A.1    Smith, C.A.2    Blain, G.M.3    Xie, A.4    Gong, Y.5    Teodorescu, M.6
  • 6
    • 0025282912 scopus 로고
    • The influence of increasing ventilatory effort on arousal from sleep
    • Gleeson K, Zwillich CW, White DP. The influence of increasing ventilatory effort on arousal from sleep. Am Rev Respir Dis 1990;142:295-300.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 295-300
    • Gleeson, K.1    Zwillich, C.W.2    White, D.P.3
  • 12
    • 0028158507 scopus 로고
    • Hypoxia selectively excites vasomotor neurons of rostral ventrolateral medulla in rats
    • Sun MK, Reis DJ. Hypoxia selectively excites vasomotor neurons of rostral ventrolateral medulla in rats. Am J Physiol 1994;266:R245-R256.
    • (1994) Am J Physiol , vol.266 , pp. R245-R256
    • Sun, M.K.1    Reis, D.J.2
  • 13
    • 0030457307 scopus 로고    scopus 로고
    • Pharmacology of reticulospinal vasomotor neurons in cardiovascular regulation
    • Sun MK. Pharmacology of reticulospinal vasomotor neurons in cardiovascular regulation. Pharmacol Rev 1996;48:465-494.
    • (1996) Pharmacol Rev , vol.48 , pp. 465-494
    • Sun, M.K.1
  • 14
    • 0027992053 scopus 로고
    • Hypoxia and electrical stimulation of the carotid sinus nerve induce Fos-like immunoreactivity within catecholaminergic and serotoninergic neurons of the rat brainstem
    • Erickson JT, Millhorn DE. Hypoxia and electrical stimulation of the carotid sinus nerve induce Fos-like immunoreactivity within catecholaminergic and serotoninergic neurons of the rat brainstem. J Comp Neurol 1994;348:161-182.
    • (1994) J Comp Neurol , vol.348 , pp. 161-182
    • Erickson, J.T.1    Millhorn, D.E.2
  • 15
    • 84875211204 scopus 로고    scopus 로고
    • Optogenetic stimulation of c1 and retrotrapezoid nucleus neurons causes sleep state-dependent cardiorespiratory stimulation and arousal in rats
    • Abbott SBG, Coates MB, Stornetta RL, Guyenet PG. Optogenetic stimulation of c1 and retrotrapezoid nucleus neurons causes sleep state-dependent cardiorespiratory stimulation and arousal in rats. Hypertension 2013;61:835-841.
    • (2013) Hypertension , vol.61 , pp. 835-841
    • Abbott, S.B.G.1    Coates, M.B.2    Stornetta, R.L.3    Guyenet, P.G.4
  • 16
    • 65949119125 scopus 로고    scopus 로고
    • Photostimulation of retrotrapezoid nucleus phox2b-expressing neurons in vivo produces long-lasting activation of breathing in rats
    • Abbott SBG, Stornetta RL, Fortuna MG, Depuy SD, West GH, Harris TE, Guyenet PG. Photostimulation of retrotrapezoid nucleus phox2b-expressing neurons in vivo produces long-lasting activation of breathing in rats. J Neurosci 2009;29:5806-5819.
    • (2009) J Neurosci , vol.29 , pp. 5806-5819
    • Abbott, S.B.G.1    Stornetta, R.L.2    Fortuna, M.G.3    Depuy, S.D.4    West, G.H.5    Harris, T.E.6    Guyenet, P.G.7
  • 17
    • 0034808550 scopus 로고    scopus 로고
    • A high-efficiency synthetic promoter that drives transgene expression selectively in noradrenergic neurons
    • Hwang DY, Carlezon WA Jr, Isacson O, Kim KS. A high-efficiency synthetic promoter that drives transgene expression selectively in noradrenergic neurons. Hum Gene Ther 2001;12:1731-1740.
    • (2001) Hum Gene Ther , vol.12 , pp. 1731-1740
    • Hwang, D.Y.1    Carlezon, W.A.2    Isacson, O.3    Kim, K.S.4
  • 21
    • 0024789611 scopus 로고
    • The C1 area of the rostral ventrolateral medulla oblongata. A critical brainstem region for control of resting and reflex integration of arterial pressure
    • Reis DJ, Ruggiero DA, Morrison SF. The C1 area of the rostral ventrolateral medulla oblongata. A critical brainstem region for control of resting and reflex integration of arterial pressure. Am J Hypertens 1989;2:363S-374S.
    • (1989) Am J Hypertens , vol.2 , pp. 363S-374S
    • Reis, D.J.1    Ruggiero, D.A.2    Morrison, S.F.3
  • 22
    • 79251526911 scopus 로고    scopus 로고
    • Comroe, Jr., distinguished lecture: Central chemoreception: Then... And now
    • Nattie E. Julius H. Comroe, Jr., distinguished lecture: central chemoreception: then ... and now. J Appl Physiol (1985) 2011;110:1-8.
    • (2011) J Appl Physiol (1985) , vol.110 , pp. 1-8
    • Nattie, E.1    Julius, H.2
  • 23
    • 84873654803 scopus 로고    scopus 로고
    • Selective optogenetic activation of rostral ventrolateral medullary catecholaminergic neurons produces cardiorespiratory stimulation in conscious mice
    • Abbott SB, DePuy SD, Nguyen T, Coates MB, Stornetta RL, Guyenet PG. Selective optogenetic activation of rostral ventrolateral medullary catecholaminergic neurons produces cardiorespiratory stimulation in conscious mice. J Neurosci 2013;33:3164-3177.
    • (2013) J Neurosci , vol.33 , pp. 3164-3177
    • Abbott, S.B.1    DePuy, S.D.2    Nguyen, T.3    Coates, M.B.4    Stornetta, R.L.5    Guyenet, P.G.6
  • 24
    • 84888231118 scopus 로고    scopus 로고
    • Monosynaptic glutamatergic activation of locus coeruleus and other lower brainstem noradrenergic neurons by the C1 cells in mice
    • Holloway BB, Stornetta RL, Bochorishvili G, Erisir A, Viar KE, Guyenet PG. Monosynaptic glutamatergic activation of locus coeruleus and other lower brainstem noradrenergic neurons by the C1 cells in mice. J Neurosci 2013;33:18792-18805.
    • (2013) J Neurosci , vol.33 , pp. 18792-18805
    • Holloway, B.B.1    Stornetta, R.L.2    Bochorishvili, G.3    Erisir, A.4    Viar, K.E.5    Guyenet, P.G.6
  • 25
    • 84862521066 scopus 로고    scopus 로고
    • C1 neurons excite locus coeruleus and A5 noradrenergic neurons along with sympathetic out flow in rats
    • Abbott SB, Kanbar R, Bochorishvili G, Coates MB, Stornetta RL, Guyenet PG. C1 neurons excite locus coeruleus and A5 noradrenergic neurons along with sympathetic out flow in rats. J Physiol 2012;590:2897-2915.
    • (2012) J Physiol , vol.590 , pp. 2897-2915
    • Abbott, S.B.1    Kanbar, R.2    Bochorishvili, G.3    Coates, M.B.4    Stornetta, R.L.5    Guyenet, P.G.6
  • 27
    • 84872732253 scopus 로고    scopus 로고
    • Glutamatergic neurotransmission between the C1 neurons and the parasympathetic preganglionic neurons of the dorsal motor nucleus of the vagus
    • DePuy SD, Stornetta RL, Bochorishvili G, Deisseroth K, Witten I, Coates M, Guyenet PG. Glutamatergic neurotransmission between the C1 neurons and the parasympathetic preganglionic neurons of the dorsal motor nucleus of the vagus. J Neurosci 2013;33:1486-1497.
    • (2013) J Neurosci , vol.33 , pp. 1486-1497
    • DePuy, S.D.1    Stornetta, R.L.2    Bochorishvili, G.3    Deisseroth, K.4    Witten, I.5    Coates, M.6    Guyenet, P.G.7
  • 28
    • 0030671530 scopus 로고    scopus 로고
    • Identification of C1 presympathetic neurons in rat rostral ventrolateral medulla by juxtacellular labeling in vivo
    • Schreihofer AM, Guyenet PG. Identification of C1 presympathetic neurons in rat rostral ventrolateral medulla by juxtacellular labeling in vivo. J Comp Neurol 1997;387:524-536.
    • (1997) J Comp Neurol , vol.387 , pp. 524-536
    • Schreihofer, A.M.1    Guyenet, P.G.2
  • 29
    • 84891630663 scopus 로고    scopus 로고
    • Vesicular glutamate transporter 2 is required for the respiratory and parasympathetic activation produced by optogenetic stimulation of catecholaminergic neurons in the rostral ventrolateral medulla of mice in vivo
    • Abbott SB, Holloway BB, Viar KE, Guyenet PG. Vesicular glutamate transporter 2 is required for the respiratory and parasympathetic activation produced by optogenetic stimulation of catecholaminergic neurons in the rostral ventrolateral medulla of mice in vivo. Eur J Neurosci 2014;39:98-106.
    • (2014) Eur J Neurosci , vol.39 , pp. 98-106
    • Abbott, S.B.1    Holloway, B.B.2    Viar, K.E.3    Guyenet, P.G.4
  • 30
    • 25644441731 scopus 로고    scopus 로고
    • Regulation of ventral surface chemoreceptors by the central respiratory pattern generator
    • Guyenet PG, Mulkey DK, Stornetta RL, Bayliss DA. Regulation of ventral surface chemoreceptors by the central respiratory pattern generator. J Neurosci 2005;25:8938-8947.
    • (2005) J Neurosci , vol.25 , pp. 8938-8947
    • Guyenet, P.G.1    Mulkey, D.K.2    Stornetta, R.L.3    Bayliss, D.A.4
  • 31
    • 0023940945 scopus 로고
    • The C1 area of the brainstem in tonic and reflex control of blood pressure. State of the art lecture
    • Reis DJ, Morrison S, Ruggiero DA. The C1 area of the brainstem in tonic and reflex control of blood pressure. State of the art lecture. Hypertension 1988;11:I8-I13.
    • (1988) Hypertension , vol.11 , pp. I8-I13
    • Reis, D.J.1    Morrison, S.2    Ruggiero, D.A.3
  • 32
    • 78049406156 scopus 로고    scopus 로고
    • The effects of baroreceptor stimulation on central respiratory drive: A review
    • McMullan S, Pilowsky PM. The effects of baroreceptor stimulation on central respiratory drive: a review. Respir Physiol Neurobiol 2010;174:37-42.
    • (2010) Respir Physiol Neurobiol , vol.174 , pp. 37-42
    • McMullan, S.1    Pilowsky, P.M.2
  • 35
    • 0021135776 scopus 로고
    • Rostral ventrolateral medulla: Selective projections to the thoracic autonomic cell column from the region containing C1 adrenaline neurons
    • Ross CA, Ruggiero DA, Joh TH, Park DH, Reis DJ. Rostral ventrolateral medulla: selective projections to the thoracic autonomic cell column from the region containing C1 adrenaline neurons. J Comp Neurol 1984;228:168-185.
    • (1984) J Comp Neurol , vol.228 , pp. 168-185
    • Ross, C.A.1    Ruggiero, D.A.2    Joh, T.H.3    Park, D.H.4    Reis, D.J.5
  • 36
    • 0015964358 scopus 로고
    • Immunohistochemical evidence for the existence of adrenaline neurons in the rat brain
    • Hokfelt T, Fuxe K, Goldstein M, Johansson O. Immunohistochemical evidence for the existence of adrenaline neurons in the rat brain. Brain Res 1974;66:235-251.
    • (1974) Brain Res , vol.66 , pp. 235-251
    • Hokfelt, T.1    Fuxe, K.2    Goldstein, M.3    Johansson, O.4
  • 37
    • 0023222034 scopus 로고
    • Organization of central adrenergic pathways: I. Relationships of ventrolateral medullary projections to the hypothalamus and spinal cord
    • Tucker DC, Saper CB, Ruggiero DA, Reis DJ. Organization of central adrenergic pathways: I. Relationships of ventrolateral medullary projections to the hypothalamus and spinal cord. J Comp Neurol 1987;259:591-603.
    • (1987) J Comp Neurol , vol.259 , pp. 591-603
    • Tucker, D.C.1    Saper, C.B.2    Ruggiero, D.A.3    Reis, D.J.4
  • 38
    • 0025228576 scopus 로고
    • Ascending collaterals of medullary barosensitive neurons and C1 cells in rats
    • Haselton JR, Guyenet PG. Ascending collaterals of medullary barosensitive neurons and C1 cells in rats. Am J Physiol 1990;258:R1051-R1063.
    • (1990) Am J Physiol , vol.258 , pp. R1051-R1063
    • Haselton, J.R.1    Guyenet, P.G.2
  • 39
    • 0022356467 scopus 로고
    • GABA-mediated baroreceptor inhibition of reticulospinal neurons
    • Sun MK, Guyenet PG. GABA-mediated baroreceptor inhibition of reticulospinal neurons. Am J Physiol 1985;249:R672-R680.
    • (1985) Am J Physiol , vol.249 , pp. R672-R680
    • Sun, M.K.1    Guyenet, P.G.2
  • 40
    • 33749020262 scopus 로고    scopus 로고
    • Channelrhodopsin-2 and optical control of excitable cells
    • Zhang F, Wang LP, Boyden ES, Deisseroth K. Channelrhodopsin-2 and optical control of excitable cells. Nat Methods 2006;3:785-792.
    • (2006) Nat Methods , vol.3 , pp. 785-792
    • Zhang, F.1    Wang, L.P.2    Boyden, E.S.3    Deisseroth, K.4
  • 41
    • 78349301247 scopus 로고    scopus 로고
    • Photostimulation of Phox2b medullary neurons activates cardiorespiratory function in conscious rats
    • Kanbar R, Stornetta RL, Cash DR, Lewis SJ, Guyenet PG. Photostimulation of Phox2b medullary neurons activates cardiorespiratory function in conscious rats. Am J Respir Crit Care Med 2010;182:1184-1194.
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 1184-1194
    • Kanbar, R.1    Stornetta, R.L.2    Cash, D.R.3    Lewis, S.J.4    Guyenet, P.G.5
  • 42
    • 80051988889 scopus 로고    scopus 로고
    • Control of sympathetic vasomotor tone by catecholaminergic C1 neurones of the rostral ventrolateral medulla oblongata
    • Marina N, Abdala AP, Korsak A, Simms AE, Allen AM, Paton JF, Gourine AV. Control of sympathetic vasomotor tone by catecholaminergic C1 neurones of the rostral ventrolateral medulla oblongata. Cardiovasc Res 2011;91:703-710.
    • (2011) Cardiovasc Res , vol.91 , pp. 703-710
    • Marina, N.1    Abdala, A.P.2    Korsak, A.3    Simms, A.E.4    Allen, A.M.5    Paton, J.F.6    Gourine, A.V.7
  • 43
    • 0029972736 scopus 로고    scopus 로고
    • Medullary vasomotor activity and hypoxic sympathoexcitation in pentobarbital-anesthetized rats
    • Sun MK, Reis DJ. Medullary vasomotor activity and hypoxic sympathoexcitation in pentobarbital-anesthetized rats. Am J Physiol 1996;270:R348-R355.
    • (1996) Am J Physiol , vol.270 , pp. R348-R355
    • Sun, M.K.1    Reis, D.J.2
  • 44
    • 80755127200 scopus 로고    scopus 로고
    • Phox2b-expressing neurons of the parafacial region regulate breathing rate, inspiration, and expiration in conscious rats
    • Abbott SB, Stornetta RL, Coates MB, Guyenet PG. Phox2b-expressing neurons of the parafacial region regulate breathing rate, inspiration, and expiration in conscious rats. J Neurosci 2011;31:16410-16422.
    • (2011) J Neurosci , vol.31 , pp. 16410-16422
    • Abbott, S.B.1    Stornetta, R.L.2    Coates, M.B.3    Guyenet, P.G.4
  • 45
    • 77956843436 scopus 로고    scopus 로고
    • Essential role of Phox2b-expressing ventrolateral brainstem neurons in the chemosensory control of inspiration and expiration
    • Marina N, Abdala AP, Trapp S, Li A, Nattie EE, Hewinson J, Smith JC, Paton JF, Gourine AV. Essential role of Phox2b-expressing ventrolateral brainstem neurons in the chemosensory control of inspiration and expiration. J Neurosci 2010;30:12466-12473.
    • (2010) J Neurosci , vol.30 , pp. 12466-12473
    • Marina, N.1    Abdala, A.P.2    Trapp, S.3    Li, A.4    Nattie, E.E.5    Hewinson, J.6    Smith, J.C.7    Paton, J.F.8    Gourine, A.V.9
  • 46
    • 33750910876 scopus 로고    scopus 로고
    • Efferent projections of rat rostroventrolateral medulla C1 catecholamine neurons: Implications for the central control of cardiovascular regulation
    • Card JP, Sved JC, Craig B, Raizada M, Vazquez J, Sved AF. Efferent projections of rat rostroventrolateral medulla C1 catecholamine neurons: Implications for the central control of cardiovascular regulation. J Comp Neurol 2006;499:840-859.
    • (2006) J Comp Neurol , vol.499 , pp. 840-859
    • Card, J.P.1    Sved, J.C.2    Craig, B.3    Raizada, M.4    Vazquez, J.5    Sved, A.F.6
  • 47
    • 78049402675 scopus 로고    scopus 로고
    • Orexin neurons as arousal-associated modulators of central cardiorespiratory regulation
    • Kuwaki T, Zhang W. Orexin neurons as arousal-associated modulators of central cardiorespiratory regulation. Respir Physiol Neurobiol 2010;174:43-54.
    • (2010) Respir Physiol Neurobiol , vol.174 , pp. 43-54
    • Kuwaki, T.1    Zhang, W.2
  • 48
    • 7044253641 scopus 로고    scopus 로고
    • Functional organization of the parabrachial complex and intertrigeminal region in the control of breathing
    • Chamberlin NL. Functional organization of the parabrachial complex and intertrigeminal region in the control of breathing. Respir Physiol Neurobiol 2004;143:115-125.
    • (2004) Respir Physiol Neurobiol , vol.143 , pp. 115-125
    • Chamberlin, N.L.1
  • 49
    • 0038613025 scopus 로고    scopus 로고
    • Defining ventral medullary respiratory compartments with a glutamate receptor agonist in the rat
    • Monnier A, Alheid GF, McCrimmon DR. Defining ventral medullary respiratory compartments with a glutamate receptor agonist in the rat. J Physiol 2003;548:859-874.
    • (2003) J Physiol , vol.548 , pp. 859-874
    • Monnier, A.1    Alheid, G.F.2    McCrimmon, D.R.3
  • 52
    • 84888170870 scopus 로고    scopus 로고
    • β-Noradrenergic receptor activation specifically modulates the generation of sighs in vivo and in vitro
    • Viemari JC, Garcia AJ III, Doi A, Elsen G, Ramirez JM. β-Noradrenergic receptor activation specifically modulates the generation of sighs in vivo and in vitro . Front Neural Circuits 2013;7:179.
    • (2013) Front Neural Circuits , vol.7 , pp. 179
    • Viemari, J.C.1    Garcia, A.J.2    Doi, A.3    Elsen, G.4    Ramirez, J.M.5
  • 53
  • 54
    • 0019855733 scopus 로고
    • Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle
    • Aston-Jones G, Bloom FE. Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle. J Neurosci 1981;1:876-886.
    • (1981) J Neurosci , vol.1 , pp. 876-886
    • Aston-Jones, G.1    Bloom, F.E.2
  • 55
    • 22244443005 scopus 로고    scopus 로고
    • Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle
    • Lee MG, Hassani OK, Jones BE. Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle. J Neurosci 2005;25:6716-6720.
    • (2005) J Neurosci , vol.25 , pp. 6716-6720
    • Lee, M.G.1    Hassani, O.K.2    Jones, B.E.3
  • 56
    • 0032844030 scopus 로고    scopus 로고
    • Activity of serotonergic neurons in behaving animals
    • Jacobs BL, Fornal CA. Activity of serotonergic neurons in behaving animals. Neuropsychopharmacology 1999; 21(2, Suppl)9S-15S.
    • (1999) Neuropsychopharmacology , vol.21 , Issue.2 , pp. 9S-15S
    • Jacobs, B.L.1    Fornal, C.A.2
  • 57
    • 84876453392 scopus 로고    scopus 로고
    • Evidence that adrenergic ventrolateral medullary cells are activated whereas precerebellar lateral reticular nucleus neurons are suppressed during REM sleep
    • Stettner GM, Lei Y, Benincasa Herr K, Kubin L. Evidence that adrenergic ventrolateral medullary cells are activated whereas precerebellar lateral reticular nucleus neurons are suppressed during REM sleep. PLoS ONE 2013;8:e62410.
    • (2013) PLoS ONE , vol.8 , pp. e62410
    • Stettner, G.M.1    Lei, Y.2    Benincasa Herr, K.3    Kubin, L.4
  • 58
    • 0031936544 scopus 로고    scopus 로고
    • Depletion of catecholaminergic neurons of the rostral ventrolateral medulla in multiple systems atrophy with autonomic failure
    • Benarroch EE, Smithson IL, Low PA, Parisi JE. Depletion of catecholaminergic neurons of the rostral ventrolateral medulla in multiple systems atrophy with autonomic failure. Ann Neurol 1998;43:156-163.
    • (1998) Ann Neurol , vol.43 , pp. 156-163
    • Benarroch, E.E.1    Smithson, I.L.2    Low, P.A.3    Parisi, J.E.4
  • 59
    • 79952057204 scopus 로고    scopus 로고
    • PHOX2B immunolocalization of the candidate human retrotrapezoid nucleus
    • Rudzinski E, Kapur RP. PHOX2B immunolocalization of the candidate human retrotrapezoid nucleus. Pediatr Dev Pathol 2010;13:291-299.
    • (2010) Pediatr Dev Pathol , vol.13 , pp. 291-299
    • Rudzinski, E.1    Kapur, R.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.