메뉴 건너뛰기




Volumn 31, Issue 45, 2011, Pages 16410-16422

Phox2b-expressing neurons of the parafacial region regulate breathing rate, inspiration, and expiration in conscious rats

Author keywords

[No Author keywords available]

Indexed keywords

CHANNELRHODOPSIN; RHODOPSIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PHOX2B; UNCLASSIFIED DRUG;

EID: 80755127200     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3280-11.2011     Document Type: Article
Times cited : (106)

References (50)
  • 1
    • 65949119125 scopus 로고    scopus 로고
    • Photostimulation of retrotrapezoid nucleus Phox2b-expressing neurons in vivo produces long-lasting activation of breathing in rats
    • Abbott SB, Stornetta RL, Fortuna MG, Depuy SD, West GH, Harris TE, Guyenet PG (2009a) Photostimulation of retrotrapezoid nucleus Phox2b-expressing neurons in vivo produces long-lasting activation of breathing in rats. J Neurosci 29:5806-5819.
    • (2009) J Neurosci , vol.29 , pp. 5806-5819
    • Abbott, S.B.1    Stornetta, R.L.2    Fortuna, M.G.3    Depuy, S.D.4    West, G.H.5    Harris, T.E.6    Guyenet, P.G.7
  • 2
    • 71249140739 scopus 로고    scopus 로고
    • Photostimulation of channelrhodopsin-2 expressing ventrolateral medullary neurons increases sympathetic nerve activity and blood pressure in rats
    • Abbott SB, Stornetta RL, Socolovsky CS, West GH, Guyenet PG (2009b) Photostimulation of channelrhodopsin-2 expressing ventrolateral medullary neurons increases sympathetic nerve activity and blood pressure in rats. J Physiol 587:5613-5631.
    • (2009) J Physiol , vol.587 , pp. 5613-5631
    • Abbott, S.B.1    Stornetta, R.L.2    Socolovsky, C.S.3    West, G.H.4    Guyenet, P.G.5
  • 3
    • 67651114060 scopus 로고    scopus 로고
    • Abdominal expiratory activity in the rat brainstem-spinal cord in situ: Patterns, origins, and implications for respiratory rhythm generation
    • Abdala AP, Rybak IA, Smith JC, Paton JF (2009) Abdominal expiratory activity in the rat brainstem-spinal cord in situ: patterns, origins, and implications for respiratory rhythm generation. J Physiol 587:3539-3559.
    • (2009) J Physiol , vol.587 , pp. 3539-3559
    • Abdala, A.P.1    Rybak, I.A.2    Smith, J.C.3    Paton, J.F.4
  • 5
    • 67649535651 scopus 로고    scopus 로고
    • Opioids prolong and anoxia shortens delay between onset of preinspiratory (pFRG) and inspiratory (preBotC) network bursting in newborn rat brainstems
    • Ballanyi K, Ruangkittisakul A, Onimaru H (2009) Opioids prolong and anoxia shortens delay between onset of preinspiratory (pFRG) and inspiratory (preBotC) network bursting in newborn rat brainstems. Pflugers Arch 458:571-587.
    • (2009) Pflugers Arch , vol.458 , pp. 571-587
    • Ballanyi, K.1    Ruangkittisakul, A.2    Onimaru, H.3
  • 6
    • 84855966164 scopus 로고    scopus 로고
    • Pre- Bötzinger complex receives glutamatergic innervation from galaninergic and other retrotrapezoid nucleus neurons
    • Retrieved Sept 20, 2011, doi:10.1002/cne.22769
    • Bochorishvili G, Coates MB, Stornetta RL, Guyenet PG (2011) Pre- Bötzinger complex receives glutamatergic innervation from galaninergic and other retrotrapezoid nucleus neurons. J Comp Neurol. Advance online publication. Retrieved Sept 20, 2011. doi:10.1002/cne.22769.
    • (2011) J Comp Neurol. Advance Online Publication
    • Bochorishvili, G.1    Coates, M.B.2    Stornetta, R.L.3    Guyenet, P.G.4
  • 7
    • 2942603395 scopus 로고    scopus 로고
    • Respiratory chemoreflexes and effects of cortical activation state in urethane anesthetized rats 8
    • Boon JA, Garnett NB, Bentley JM, Milsom WK (2004) Respiratory chemoreflexes and effects of cortical activation state in urethane anesthetized rats 8. Respir Physiol Neurobiol 140:243-256.
    • (2004) Respir Physiol Neurobiol , vol.140 , pp. 243-256
    • Boon, J.A.1    Garnett, N.B.2    Bentley, J.M.3    Milsom, W.K.4
  • 9
    • 0023193686 scopus 로고
    • Afferent and efferent connections of the A5 noradrenergic cell group in the rat
    • Byrum CE, Guyenet PG (1987) Afferent and efferent connections of the A5 noradrenergic cell group in the rat. J Comp Neurol 261:529-542.
    • (1987) J Comp Neurol , vol.261 , pp. 529-542
    • Byrum, C.E.1    Guyenet, P.G.2
  • 10
    • 33750910876 scopus 로고    scopus 로고
    • Efferent projections of rat rostroventrolateral medulla C1 catecholamine neurons: Implications for the central control of cardiovascular regulation
    • Card JP, Sved JC, Craig B, Raizada M, Vazquez J, Sved AF (2006) Efferent projections of rat rostroventrolateral medulla C1 catecholamine neurons: Implications for the central control of cardiovascular regulation. J Comp Neurol 499:840-859.
    • (2006) J Comp Neurol , vol.499 , pp. 840-859
    • Card, J.P.1    Sved, J.C.2    Craig, B.3    Raizada, M.4    Vazquez, J.5    Sved, A.F.6
  • 11
    • 0002834878 scopus 로고
    • A barometric method for measuring ventilation in newborn infants 1
    • Drorbaugh JE, Fenn WO (1955) A barometric method for measuring ventilation in newborn infants 1. Pediatrics 16:81-87.
    • (1955) Pediatrics , vol.16 , pp. 81-87
    • Drorbaugh, J.E.1    Fenn, W.O.2
  • 12
    • 0019390486 scopus 로고
    • Input-output relationships of central neural circuits involved in respiration in cats
    • Eldridge FL, Gill-Kumar P, Millhorn DE (1981) Input-output relationships of central neural circuits involved in respiration in cats. J Physiol 311:81-95.
    • (1981) J Physiol , vol.311 , pp. 81-95
    • Eldridge, F.L.1    Gill-Kumar, P.2    Millhorn, D.E.3
  • 13
    • 79951604027 scopus 로고    scopus 로고
    • Chapter 14-looking forward to breathing 4
    • Feldman JL (2011) Chapter 14-looking forward to breathing 4. Prog Brain Res 188:213-218.
    • (2011) Prog Brain Res , vol.188 , pp. 213-218
    • Feldman, J.L.1
  • 14
    • 70450214121 scopus 로고    scopus 로고
    • Activation of the retrotrapezoid nucleus by posterior hypothalamic stimulation
    • Fortuna MG, Stornetta RL, West GH, Guyenet PG (2009) Activation of the retrotrapezoid nucleus by posterior hypothalamic stimulation. J Physiol 587:5121-5138.
    • (2009) J Physiol , vol.587 , pp. 5121-5138
    • Fortuna, M.G.1    Stornetta, R.L.2    West, G.H.3    Guyenet, P.G.4
  • 15
    • 77957048533 scopus 로고    scopus 로고
    • Central chemoreception: Lessons from mouse and human genetics
    • Goridis C, Brunet JF (2010) Central chemoreception: lessons from mouse and human genetics. Respir Physiol Neurobiol 173:312-321.
    • (2010) Respir Physiol Neurobiol , vol.173 , pp. 312-321
    • Goridis, C.1    Brunet, J.F.2
  • 17
    • 25644441731 scopus 로고    scopus 로고
    • Regulation of ventral surface chemoreceptors by the central respiratory pattern generator
    • Guyenet PG, Mulkey DK, Stornetta RL, Bayliss DA (2005) Regulation of ventral surface chemoreceptors by the central respiratory pattern generator. J Neurosci 25:8938-8947.
    • (2005) J Neurosci , vol.25 , pp. 8938-8947
    • Guyenet, P.G.1    Mulkey, D.K.2    Stornetta, R.L.3    Bayliss, D.A.4
  • 19
    • 64349123325 scopus 로고    scopus 로고
    • Control of breathing and volitional respiratory rhythm in humans
    • Haouzi P, Bell HJ (2009) Control of breathing and volitional respiratory rhythm in humans. J Appl Physiol 106:904-910.
    • (2009) J Appl Physiol , vol.106 , pp. 904-910
    • Haouzi, P.1    Bell, H.J.2
  • 20
    • 0034808550 scopus 로고    scopus 로고
    • A high-efficiency synthetic promoter that drives transgene expression selectively in noradrenergic neurons
    • Hwang DY, Carlezon WA Jr, Isacson O, Kim KS (2001) A high-efficiency synthetic promoter that drives transgene expression selectively in noradrenergic neurons. Hum Gene Ther 12:1731-1740.
    • (2001) Hum Gene Ther , vol.12 , pp. 1731-1740
    • Hwang, D.Y.1    Carlezon Jr., W.A.2    Isacson, O.3    Kim, K.S.4
  • 21
    • 0031698170 scopus 로고    scopus 로고
    • Control of abdominal muscles
    • Iscoe S (1998) Control of abdominal muscles. Prog Neurobiol 56:433-506.
    • (1998) Prog Neurobiol , vol.56 , pp. 433-506
    • Iscoe, S.1
  • 22
    • 33644559872 scopus 로고    scopus 로고
    • Distinct rhythm generators for inspiration and expiration in the juvenile rat
    • Janczewski WA, Feldman JL (2006) Distinct rhythm generators for inspiration and expiration in the juvenile rat. J Physiol 570:407-420.
    • (2006) J Physiol , vol.570 , pp. 407-420
    • Janczewski, W.A.1    Feldman, J.L.2
  • 23
    • 78349301247 scopus 로고    scopus 로고
    • Photostimulation of Phox2b medullary neurons activates cardiorespiratory function in conscious rats
    • Kanbar R, Stornetta RL, Cash DR, Lewis SJ, Guyenet PG (2010) Photostimulation of Phox2b medullary neurons activates cardiorespiratory function in conscious rats. Am J Respir Crit Care Med 182:1184-1194.
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 1184-1194
    • Kanbar, R.1    Stornetta, R.L.2    Cash, D.R.3    Lewis, S.J.4    Guyenet, P.G.5
  • 26
    • 0037163848 scopus 로고    scopus 로고
    • 2 dialysis in one chemoreceptor site, the RTN: Stimulus intensity and sensitivity in the awake rat
    • Li A, Nattie E (2002) CO2 dialysis in one chemoreceptor site, the RTN: stimulus intensity and sensitivity in the awake rat. Respir Physiol Neurobiol 133:11-22.
    • (2002) Respir Physiol Neurobiol , vol.133 , pp. 11-22
    • Li, A.1    Nattie, E.2
  • 27
    • 77956843436 scopus 로고    scopus 로고
    • Essential role of Phox2b-expressing ventrolateral brainstem neurons in the chemosensory control of inspiration and expiration
    • Marina N, Abdala AP, Trapp S, Li A, Nattie EE, Hewinson J, Smith JC, Paton JF, Gourine AV (2010) Essential role of Phox2b-expressing ventrolateral brainstem neurons in the chemosensory control of inspiration and expiration. J Neurosci 30:12466-12473.
    • (2010) J Neurosci , vol.30 , pp. 12466-12473
    • Marina, N.1    Abdala, A.P.2    Trapp, S.3    Li, A.4    Nattie, E.E.5    Hewinson, J.6    Smith, J.C.7    Paton, J.F.8    Gourine, A.V.9
  • 28
    • 0037422029 scopus 로고    scopus 로고
    • Opioidinduced quantal slowing reveals dual networks for respiratory rhythm generation
    • Mellen NM, Janczewski WA, Bocchiaro CM, Feldman JL (2003) Opioidinduced quantal slowing reveals dual networks for respiratory rhythm generation. Neuron 37:821-826.
    • (2003) Neuron , vol.37 , pp. 821-826
    • Mellen, N.M.1    Janczewski, W.A.2    Bocchiaro, C.M.3    Feldman, J.L.4
  • 30
    • 33947508131 scopus 로고    scopus 로고
    • Inhibitory input from slowly adapting lung stretch receptors to retrotrapezoid nucleus chemoreceptors
    • Moreira TS, Takakura AC, Colombari E, West GH, Guyenet PG (2007) Inhibitory input from slowly adapting lung stretch receptors to retrotrapezoid nucleus chemoreceptors. J Physiol 580:285-300.
    • (2007) J Physiol , vol.580 , pp. 285-300
    • Moreira, T.S.1    Takakura, A.C.2    Colombari, E.3    West, G.H.4    Guyenet, P.G.5
  • 32
    • 66149145268 scopus 로고    scopus 로고
    • Central chemoreception is a complex system function that involves multiple brain stem sites
    • Nattie E, Li A (2009) Central chemoreception is a complex system function that involves multiple brain stem sites. J Appl Physiol 106:1464-1466.
    • (2009) J Appl Physiol , vol.106 , pp. 1464-1466
    • Nattie, E.1    Li, A.2
  • 33
    • 36249012542 scopus 로고    scopus 로고
    • Postnatal developmental changes in activation profiles of the respiratory neuronal network in the rat ventral medulla
    • Oku Y, Masumiya H, Okada Y (2007) Postnatal developmental changes in activation profiles of the respiratory neuronal network in the rat ventral medulla. J Physiol 585:175-186.
    • (2007) J Physiol , vol.585 , pp. 175-186
    • Oku, Y.1    Masumiya, H.2    Okada, Y.3
  • 34
    • 0037442811 scopus 로고    scopus 로고
    • A novel functional neuron group for respiratory rhythm generation in the ventral medulla
    • Onimaru H, Homma I (2003) A novel functional neuron group for respiratory rhythm generation in the ventral medulla. J Neurosci 23:1478-1486.
    • (2003) J Neurosci , vol.23 , pp. 1478-1486
    • Onimaru, H.1    Homma, I.2
  • 35
    • 58149393861 scopus 로고    scopus 로고
    • 2-sensitive preinspiratory neurons of the parafacial respiratory group express Phox2b in the neonatal Rat
    • Onimaru H, Ikeda K, Kawakami K (2008) CO2-sensitive preinspiratory neurons of the parafacial respiratory group express Phox2b in the neonatal Rat. J Neurosci 28:12845-12850.
    • (2008) J Neurosci , vol.28 , pp. 12845-12850
    • Onimaru, H.1    Ikeda, K.2    Kawakami, K.3
  • 37
    • 0030731439 scopus 로고    scopus 로고
    • Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis
    • Pattyn A, Morin X, Cremer H, Goridis C, Brunet JF (1997) Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis. Development 124:4065-4075.
    • (1997) Development , vol.124 , pp. 4065-4075
    • Pattyn, A.1    Morin, X.2    Cremer, H.3    Goridis, C.4    Brunet, J.F.5
  • 39
    • 14244252661 scopus 로고    scopus 로고
    • Respiratory rhythm entrainment by somatic afferent stimulation
    • Potts JT, Rybak IA, Paton JF (2005) Respiratory rhythm entrainment by somatic afferent stimulation. J Neurosci 25:1965-1978.
    • (2005) J Neurosci , vol.25 , pp. 1965-1978
    • Potts, J.T.1    Rybak, I.A.2    Paton, J.F.3
  • 40
    • 33748879744 scopus 로고    scopus 로고
    • Afferent and efferent connections of the rat retrotrapezoid nucleus
    • Rosin DL, Chang DA, Guyenet PG (2006) Afferent and efferent connections of the rat retrotrapezoid nucleus. J Comp Neurol 499:64-89.
    • (2006) J Comp Neurol , vol.499 , pp. 64-89
    • Rosin, D.L.1    Chang, D.A.2    Guyenet, P.G.3
  • 42
    • 0024521176 scopus 로고
    • Brainstem projections to the major respiratory neuron populations in the medulla of the cat
    • Smith JC, Morrison DE, Ellenberger HH, Otto MR, Feldman JL (1989) Brainstem projections to the major respiratory neuron populations in the medulla of the cat. J Comp Neurol 281:69-96.
    • (1989) J Comp Neurol , vol.281 , pp. 69-96
    • Smith, J.C.1    Morrison, D.E.2    Ellenberger, H.H.3    Otto, M.R.4    Feldman, J.L.5
  • 43
    • 0037066060 scopus 로고    scopus 로고
    • Vesicular glutamate transporter DNPI/VGLUT2mRNAis present in C1 and several other groups of brainstem catecholaminergic neurons
    • Stornetta RL, Sevigny CP, Guyenet PG (2002) Vesicular glutamate transporter DNPI/VGLUT2mRNAis present in C1 and several other groups of brainstem catecholaminergic neurons. J Comp Neurol 444:191-206.
    • (2002) J Comp Neurol , vol.444 , pp. 191-206
    • Stornetta, R.L.1    Sevigny, C.P.2    Guyenet, P.G.3
  • 45
    • 80755182122 scopus 로고    scopus 로고
    • Photostimulation of channelrhodopsin2(ChR2)-transfected C1 neurons increases sympathetic nerve discharge (SND) and blood pressure (BP) in rats
    • Abstr 35:467.5
    • Stornetta RL, Abbott SBG, Kanbar R, Guyenet PG (2009) Photostimulation of channelrhodopsin2(ChR2)-transfected C1 neurons increases sympathetic nerve discharge (SND) and blood pressure (BP) in rats. Soc Neurosci Abstr 35:467.5.
    • (2009) Soc Neurosci
    • Stornetta, R.L.1    Abbott, S.B.G.2    Kanbar, R.3    Guyenet, P.G.4
  • 47
    • 45249119097 scopus 로고    scopus 로고
    • Selective lesion of retrotrapezoid Phox2b-expressing neurons raises the apnoeic threshold in rats
    • Takakura AC, Moreira TS, Stornetta RL, West GH, Gwilt JM, Guyenet PG (2008) Selective lesion of retrotrapezoid Phox2b-expressing neurons raises the apnoeic threshold in rats. J Physiol 586:2975-2991.
    • (2008) J Physiol , vol.586 , pp. 2975-2991
    • Takakura, A.C.1    Moreira, T.S.2    Stornetta, R.L.3    West, G.H.4    Gwilt, J.M.5    Guyenet, P.G.6
  • 48
    • 79551529524 scopus 로고    scopus 로고
    • Ventrolateral medulla mechanisms involved in cardiorespiratory responses to central chemoreceptor activation in rats
    • Takakura AC, Colombari E, Menani JV, Moreira TS (2011) Ventrolateral medulla mechanisms involved in cardiorespiratory responses to central chemoreceptor activation in rats. Am J Physiol Regul Integr Comp Physiol 300:R501-R510.
    • (2011) Am J Physiol Regul Integr Comp Physiol , vol.300
    • Takakura, A.C.1    Colombari, E.2    Menani, J.V.3    Moreira, T.S.4
  • 49
    • 68149100811 scopus 로고    scopus 로고
    • Genetic identification of an embryonic parafacial oscillator coupling to the preBotzinger complex
    • Thoby-Brisson M, Karlén M, Wu N, Charnay P, Champagnat J, Fortin G (2009) Genetic identification of an embryonic parafacial oscillator coupling to the preBotzinger complex. Nat Neurosci 12:1028-1035.
    • (2009) Nat Neurosci , vol.12 , pp. 1028-1035
    • Thoby-Brisson, M.1    Karlén, M.2    Wu, N.3    Charnay, P.4    Champagnat, J.5    Fortin, G.6
  • 50
    • 56649102271 scopus 로고    scopus 로고
    • Pacemakers handshake synchronization mechanism of mammalian respiratory rhythmogenesis
    • Wittmeier S, Song G, Duffin J, Poon CS (2008) Pacemakers handshake synchronization mechanism of mammalian respiratory rhythmogenesis. Proc Natl Acad Sci U S A 105:18000-18005.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 18000-18005
    • Wittmeier, S.1    Song, G.2    Duffin, J.3    Poon, C.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.