Ghrelin augments murine T-cell proliferation by activation of the phosphatidylinositol-3-kinase, extracellular signal-regulated kinase and protein kinase C signaling pathways

FEBS Letters

Volumn 588, Issue 24, 2014, Pages 4708-4719

  Lee, Jun Ho ^a,b   Patel, Kalpesh ^a   Tae, Hyun Jin ^a   Lustig, Ana ^a   Kim, Jie Wan ^a   Mattson, Mark P ^a   Taub, Dennis D ^a,c  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b Korea University College of Medicine   (South Korea)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Ghrelin; Glucocorticoid; Proliferation; Signaling; Stress; T cell; Thymus

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN E; GHRELIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; RETINOBLASTOMA PROTEIN; DEXAMETHASONE; GHRELIN RECEPTOR; GHSR1A PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN KINASE B;

ANIMAL CELL; ARTICLE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; GENETIC TRANSFECTION; HORMONE ACTION; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; THYMOCYTE; ANIMAL; CELL CYCLE; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; RAT;

MURINAE; MUS;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL CYCLE; CELL PROLIFERATION; DEXAMETHASONE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; GHRELIN; LYMPHOCYTE ACTIVATION; MALE; MAP KINASE SIGNALING SYSTEM; MICE; PHOSPHATIDYLINOSITOL 3-KINASE; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, GHRELIN; THYMOCYTES;

EID: 84915820696     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.10.044     Document Type: Article

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