메뉴 건너뛰기




Volumn 150, Issue 9, 2009, Pages 4163-4169

Thymocyte-synthesized glucocorticoids play a role in thymocyte homeostasis and are down-regulated by adrenocorticotropic hormone

Author keywords

[No Author keywords available]

Indexed keywords

8 BROMO CYCLIC AMP; CORTICOSTERONE; CORTICOTROPIN; CORTICOTROPIN RECEPTOR; CYCLIC AMP; CYP11B1; GLUCOCORTICOID; INTERLEUKIN 18; INTERLEUKIN 1BETA; MESSENGER RNA; METYRAPONE; OXYGENASE; UNCLASSIFIED DRUG;

EID: 69249150559     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2009-0195     Document Type: Article
Times cited : (38)

References (34)
  • 1
    • 4444319484 scopus 로고    scopus 로고
    • Immunomodulatory activities of glucocorticoids: Insights from transgenesis and gene targeting
    • Reichardt HM 2004 Immunomodulatory activities of glucocorticoids: insights from transgenesis and gene targeting. Curr Pharm Des 10:2797-2805
    • (2004) Curr Pharm Des , vol.10 , pp. 2797-2805
    • Reichardt, H.M.1
  • 2
    • 5644233890 scopus 로고    scopus 로고
    • Different roles for glucocorticoids in thymocyte homeostasis?
    • Jondal M, Pazirandeh A, Okret S 2004 Different roles for glucocorticoids in thymocyte homeostasis? Trends Immunol 25:595-600
    • (2004) Trends Immunol , vol.25 , pp. 595-600
    • Jondal, M.1    Pazirandeh, A.2    Okret, S.3
  • 4
    • 1342330548 scopus 로고    scopus 로고
    • Neurosteroid biosynthesis in the human brain and its clinical implications
    • Stoffel-Wagner B 2003 Neurosteroid biosynthesis in the human brain and its clinical implications. Ann NY Acad Sci 1007:64-78
    • (2003) Ann NY Acad Sci , vol.1007 , pp. 64-78
    • Stoffel-Wagner, B.1
  • 5
    • 0028233225 scopus 로고
    • Steroid production in the thymus: Implications for thymocyte selection
    • Vacchio MS, Papadopoulos V, Ashwell JD 1994 Steroid production in the thymus: Implications for thymocyte selection. J Exp Med 179:1835-1846
    • (1994) J Exp Med , vol.179 , pp. 1835-1846
    • Vacchio, M.S.1    Papadopoulos, V.2    Ashwell, J.D.3
  • 6
    • 0032896835 scopus 로고    scopus 로고
    • Paracrine glucocorticoid activity produced by mouse thymic epithelial cells
    • Pazirandeh A, Xue Y, Rafter I, Sjövall J, Jondal M, Okret S 1999 Paracrine glucocorticoid activity produced by mouse thymic epithelial cells. FASEB J 13:893-901
    • (1999) FASEB J , vol.13 , pp. 893-901
    • Pazirandeh, A.1    Xue, Y.2    Rafter, I.3    Sjövall, J.4    Jondal, M.5    Okret, S.6
  • 8
    • 51649089799 scopus 로고    scopus 로고
    • Age-related synthesis of glucocorticoids in thymocytes
    • Qiao S, Chen L, Okret S, Jondal M 2008 Age-related synthesis of glucocorticoids in thymocytes. Exp Cell Res 314:3027-3035
    • (2008) Exp Cell Res , vol.314 , pp. 3027-3035
    • Qiao, S.1    Chen, L.2    Okret, S.3    Jondal, M.4
  • 9
    • 0033179257 scopus 로고    scopus 로고
    • Thymus-derived glucocorticoids set the thresholds for thymocyte selection by inhibiting TCR-mediated thymocyte activation
    • Vacchio MS, Lee JY, Ashwell JD 1999 Thymus-derived glucocorticoids set the thresholds for thymocyte selection by inhibiting TCR-mediated thymocyte activation. J Immunol 163:1327-1333
    • (1999) J Immunol , vol.163 , pp. 1327-1333
    • Vacchio, M.S.1    Lee, J.Y.2    Ashwell, J.D.3
  • 10
    • 18844421375 scopus 로고    scopus 로고
    • Conditional expression of a glucocorticoid receptor transgene in thymocytes reveals a role for thymic-derived glucocorticoids in thymopoiesis in vivo
    • Pazirandeh A, Jondal M, Okret S 2005 Conditional expression of a glucocorticoid receptor transgene in thymocytes reveals a role for thymic-derived glucocorticoids in thymopoiesis in vivo. Endocrinology 146:2501-2507
    • (2005) Endocrinology , vol.146 , pp. 2501-2507
    • Pazirandeh, A.1    Jondal, M.2    Okret, S.3
  • 11
    • 58249110646 scopus 로고    scopus 로고
    • Regulation of glucocorticoid sensitivity in thymocytes from burn-injured mice
    • D'Elia M, Patenaude J, Bernier J 2009 Regulation of glucocorticoid sensitivity in thymocytes from burn-injured mice. Am J Physiol Endocrinol Metab 296:E97-E104
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • D'Elia, M.1    Patenaude, J.2    Bernier, J.3
  • 13
    • 0032905515 scopus 로고    scopus 로고
    • Regulation of the hypothalamic- pituitary-adrenal axis by cytokines: Actions and mechanisms of action
    • Turnbull AV, Rivier CL 1999 Regulation of the hypothalamic- pituitary-adrenal axis by cytokines: actions and mechanisms of action. Physiol Rev 1:1-71
    • (1999) Physiol Rev , vol.1 , pp. 1-71
    • Turnbull, A.V.1    Rivier, C.L.2
  • 14
    • 0033330663 scopus 로고    scopus 로고
    • Clinical review 104: Adrenocorticotropin (ACTH)- and non-ACTH-mediated regulation of the adrenal cortex: neural and immune inputs
    • Bornstein SR, Chrousos GP 1999 Clinical review 104: adrenocorticotropin (ACTH)- and non-ACTH-mediated regulation of the adrenal cortex: neural and immune inputs. J Clin Endocrinol Metab 84:1729-1717
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 1729-1717
    • Bornstein, S.R.1    Chrousos, G.P.2
  • 16
    • 0033528445 scopus 로고    scopus 로고
    • Activation of the hypothalamic-pituitary axis in adrenalectomised rats: Potentiation by chronic stress
    • Martí O, Harbuz MS, Andrés R, Lightman SL, Armario A 1999 Activation of the hypothalamic-pituitary axis in adrenalectomised rats: potentiation by chronic stress. Brain Res 1:1-7
    • (1999) Brain Res , vol.1 , pp. 1-7
    • Martí, O.1    Harbuz, M.S.2    Andrés, R.3    Lightman, S.L.4    Armario, A.5
  • 17
    • 0032482168 scopus 로고    scopus 로고
    • Production of mice deficient in genes for interleukin (IL)-1α, IL-1β, IL-1α/β, and IL-1 receptor antagonist shows that IL-1β is crucial in turpentine-induced fever development and glucocorticoid secretion
    • Horai R, Asano M, Sudo K, Kanuka H, Suzuki M, Nishihara M, Takahashi M, Iwakura Y 1998 Production of mice deficient in genes for interleukin (IL)-1α, IL-1β, IL-1α/β, and IL-1 receptor antagonist shows that IL-1β is crucial in turpentine-induced fever development and glucocorticoid secretion. J Exp Med 187:1463-1475
    • (1998) J Exp Med , vol.187 , pp. 1463-1475
    • Horai, R.1    Asano, M.2    Sudo, K.3    Kanuka, H.4    Suzuki, M.5    Nishihara, M.6    Takahashi, M.7    Iwakura, Y.8
  • 18
    • 0141450546 scopus 로고    scopus 로고
    • The role of endogenous interleukin-1 in stress-induced adrenal activation and adrenalectomy-induced adrenocorticotropic hormone hypersecretion
    • Goshen I, Yirmiya R, Iverfeldt K, Weidenfeld J 2003 The role of endogenous interleukin-1 in stress-induced adrenal activation and adrenalectomy-induced adrenocorticotropic hormone hypersecretion. Endocrinology 144:4453-4458
    • (2003) Endocrinology , vol.144 , pp. 4453-4458
    • Goshen, I.1    Yirmiya, R.2    Iverfeldt, K.3    Weidenfeld, J.4
  • 19
    • 85025395076 scopus 로고    scopus 로고
    • Jaffe HL 1924 The influence of the supraadrenal gland on the thymus. I. Regeneration of the thymus following double supraadrenalectomy in the rat. J Exp Med 40:325-342
    • Jaffe HL 1924 The influence of the supraadrenal gland on the thymus. I. Regeneration of the thymus following double supraadrenalectomy in the rat. J Exp Med 40:325-342
  • 20
    • 0033952755 scopus 로고    scopus 로고
    • Effect of adrenalectomy on ethanol-associated changes in lymphocyte cell numbers and subpopulations in thymus, spleen, and gut-associated lymphoid tissues
    • Padgett EL, Sibley DA, Jerrells TR 2000 Effect of adrenalectomy on ethanol-associated changes in lymphocyte cell numbers and subpopulations in thymus, spleen, and gut-associated lymphoid tissues. Int J Immunopharmacol 22:285-298
    • (2000) Int J Immunopharmacol , vol.22 , pp. 285-298
    • Padgett, E.L.1    Sibley, D.A.2    Jerrells, T.R.3
  • 21
    • 0022355275 scopus 로고
    • The effects of stress in normal and adrenalectomized mice
    • Rocha B 1985 The effects of stress in normal and adrenalectomized mice. Eur J Immunol 15:1131-1135
    • (1985) Eur J Immunol , vol.15 , pp. 1131-1135
    • Rocha, B.1
  • 22
    • 0029818581 scopus 로고    scopus 로고
    • Thymocyte and splenocyte subpopulations in normal and leukemia-bearing mice after adrenalectomy
    • Kawiak J, Hoser G, Malendowicz LK, Miks B, Skurzak H 1996 Thymocyte and splenocyte subpopulations in normal and leukemia-bearing mice after adrenalectomy. Folia Histochem Cytobiol 34:75-78
    • (1996) Folia Histochem Cytobiol , vol.34 , pp. 75-78
    • Kawiak, J.1    Hoser, G.2    Malendowicz, L.K.3    Miks, B.4    Skurzak, H.5
  • 23
    • 34548681634 scopus 로고    scopus 로고
    • Role of calcium messenger systems in ACTH-induced cortisol production in bovine adrenal fasciculo-reticularis cells
    • Omura M, Suematsu S, Nishikawa T 2007 Role of calcium messenger systems in ACTH-induced cortisol production in bovine adrenal fasciculo-reticularis cells. Endocr J 54:585-592
    • (2007) Endocr J , vol.54 , pp. 585-592
    • Omura, M.1    Suematsu, S.2    Nishikawa, T.3
  • 24
    • 0036291386 scopus 로고    scopus 로고
    • Cyclic AMP-dependent signaling aberrations in macronodular adrenal disease
    • Bourdeau I, Stratakis CA 2002 Cyclic AMP-dependent signaling aberrations in macronodular adrenal disease. Ann NY Acad Sci 968:240-255
    • (2002) Ann NY Acad Sci , vol.968 , pp. 240-255
    • Bourdeau, I.1    Stratakis, C.A.2
  • 25
    • 0034893279 scopus 로고    scopus 로고
    • ACTH receptor distribution and modulation among murine mononuclear leukocyte populations
    • Johnson EW, Hughes Jr TK, Smith EM 2001 ACTH receptor distribution and modulation among murine mononuclear leukocyte populations. J Biol Regul Homeost Agents 15:156-162
    • (2001) J Biol Regul Homeost Agents , vol.15 , pp. 156-162
    • Johnson, E.W.1    Hughes Jr, T.K.2    Smith, E.M.3
  • 26
    • 33847042331 scopus 로고    scopus 로고
    • Differential regulation of glucocorticoid synthesis in murine intestinal epithelial versus adrenocortical cell lines
    • Mueller M, Atanasov A, Cima I, Corazza N, Schoonjans K, Brunner T 2007 Differential regulation of glucocorticoid synthesis in murine intestinal epithelial versus adrenocortical cell lines. Endocrinology 148:1445-1453
    • (2007) Endocrinology , vol.148 , pp. 1445-1453
    • Mueller, M.1    Atanasov, A.2    Cima, I.3    Corazza, N.4    Schoonjans, K.5    Brunner, T.6
  • 27
    • 33746583965 scopus 로고    scopus 로고
    • Caspase-1-mediated activation of interleukin-1β (IL-1β) and IL-18 contributes to innate immune defenses against Salmonella enterica serovar Typhimurium infection
    • Raupach B, Peuschel SK, Monack DM, Zychlinsky A 2006 Caspase-1-mediated activation of interleukin-1β (IL-1β) and IL-18 contributes to innate immune defenses against Salmonella enterica serovar Typhimurium infection. Infect Immun 74:4922-4926
    • (2006) Infect Immun , vol.74 , pp. 4922-4926
    • Raupach, B.1    Peuschel, S.K.2    Monack, D.M.3    Zychlinsky, A.4
  • 28
    • 33750580090 scopus 로고    scopus 로고
    • Caspase-1 regulates Escherichia coli sepsis and splenic B cell apoptosis independently of interleukin-1β and interleukin-18
    • Sarkar A, Hall MW, Exline M, Hart J, Knatz N, Gatson NT, Wewers MD 2006 Caspase-1 regulates Escherichia coli sepsis and splenic B cell apoptosis independently of interleukin-1β and interleukin-18. Am J Respir Crit Care Med 174:1003-1010
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 1003-1010
    • Sarkar, A.1    Hall, M.W.2    Exline, M.3    Hart, J.4    Knatz, N.5    Gatson, N.T.6    Wewers, M.D.7
  • 29
    • 0036668577 scopus 로고    scopus 로고
    • cAMP-dependent transcription of steroidogenic genes in the human adrenal cortex requires a dual-specificity phosphatase in addition to protein kinase Am
    • Sewer MB, Waterman MR 2002 cAMP-dependent transcription of steroidogenic genes in the human adrenal cortex requires a dual-specificity phosphatase in addition to protein kinase Am J Mol Endocrinol 29:163-174
    • (2002) J Mol Endocrinol , vol.29 , pp. 163-174
    • Sewer, M.B.1    Waterman, M.R.2
  • 30
    • 45549096896 scopus 로고    scopus 로고
    • Interleukin-18 and stress
    • Sugama S, Conti B 2008 Interleukin-18 and stress. Brain Res Rev 58:85-95
    • (2008) Brain Res Rev , vol.58 , pp. 85-95
    • Sugama, S.1    Conti, B.2
  • 31
    • 0034694892 scopus 로고    scopus 로고
    • Glucocorticoid-induced apoptosis in lymphocytes
    • Planey SL, Litwack G 2000 Glucocorticoid-induced apoptosis in lymphocytes. Biochem Biophys Res Commun 279:307-312
    • (2000) Biochem Biophys Res Commun , vol.279 , pp. 307-312
    • Planey, S.L.1    Litwack, G.2
  • 32
    • 0036120669 scopus 로고    scopus 로고
    • Immunoregulatory functions of interleukin 18 and its role in defense against bacterial pathogens
    • Biet F, Locht C, Kremer L 2002 Immunoregulatory functions of interleukin 18 and its role in defense against bacterial pathogens. J Mol Med 80:147-162
    • (2002) J Mol Med , vol.80 , pp. 147-162
    • Biet, F.1    Locht, C.2    Kremer, L.3
  • 33
    • 0032006752 scopus 로고    scopus 로고
    • Restraint stress-induced thymic involution and cell apoptosis are dependent on endogenous glucocorticoids
    • Tarcic N, Ovadia H, Weiss DW, Weidenfeld J 1998 Restraint stress-induced thymic involution and cell apoptosis are dependent on endogenous glucocorticoids. J Neuroimmunol 82:40-46
    • (1998) J Neuroimmunol , vol.82 , pp. 40-46
    • Tarcic, N.1    Ovadia, H.2    Weiss, D.W.3    Weidenfeld, J.4
  • 34
    • 38649132889 scopus 로고    scopus 로고
    • Assessment of in vitro effects of metyrapone on Leydig cell steroidogenesis
    • Parthasarathy C, Balasubramanian K 2008 Assessment of in vitro effects of metyrapone on Leydig cell steroidogenesis. Steroids 73:328-338
    • (2008) Steroids , vol.73 , pp. 328-338
    • Parthasarathy, C.1    Balasubramanian, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.