SCOPUS 정보 검색 플랫폼

Volumn 20, Issue 45, 2014, Pages 14698-14704

Design and synthesis of new hybrid molecules that activate the transcription factor Nrf2 and simultaneously release carbon monoxide

(11) Wilson, Jayne Louise a Kobeissi, Sarah Fayad a Oudir, Souhila b Haas, Benjamin a Michel, Brian c Randé, Jean Luc Dubois d Ollivier, Anthony b Martens, Thierry b Rivard, Michael b Motterlini, Roberto a Foresti, Roberta a

a FACULTÉ DE MÉDECINE (France)

b CNRS Université Paris Est Créteil Val de Marne (France)

c UNIVERSITY OF CALIFORNIA (United States)

d HENRI MONDOR HOSPITAL (France)

Author keywords

Biological activity; Drug design; Enzymes; Fluorescent probes; Heme proteins

Indexed keywords

BIOACTIVITY; CARBON; CARBON MONOXIDE; ENZYMES; FLUORESCENCE; MOLECULES; PORPHYRINS; PROBES; TRANSCRIPTION; TRANSCRIPTION FACTORS;

DOWNSTREAM TARGET; DRUG DESIGN; ENZYMATIC ACTIVITIES; FLUORESCENT PROBES; HEME PROTEINS; HYBRID COMPOUNDS; NUCLEAR ACCUMULATION; PROTECTIVE SYSTEMS;

SYNTHESIS (CHEMICAL);

ALKYNE; CARBON MONOXIDE; COBALT; COORDINATION COMPOUND; ESTER; HEME OXYGENASE 1; PHARMACOLOGY; TRANSCRIPTION FACTOR NRF2;

ANIMAL; CHEMISTRY; DRUG DESIGN; DRUG EFFECTS; MACROPHAGE; METABOLISM; MOUSE; OXIDATIVE STRESS; SYNTHESIS;

ALKYNES; ANIMALS; CARBON MONOXIDE; CHEMICAL SYNTHESIS; CHEMISTRY; COBALT; COORDINATION COMPLEXES; DRUG DESIGN; DRUG EFFECTS; ESTERS; HEME OXYGENASE-1; MACROPHAGES; METABOLISM; MICE; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PHARMACOLOGY;

EID: 84915819052 PISSN: 09476539 EISSN: 15213765 Source Type: Journal
DOI: 10.1002/chem.201403901 Document Type: Article

Times cited : (50)

References (46)

1
- 0034717329
- T. Ishii, K. Itoh, S. Takahashi, H. Sato, T. Yanagawa, Y. Katoh, S. Bannai, M. Yamamoto, J. Biol. Chem. 2000, 275, 16023-16029.
- (2000) J. Biol. Chem. , vol.275 , pp. 16023-16029
- Ishii, T.¹ Itoh, K.² Takahashi, S.³ Sato, H.⁴ Yanagawa, T.⁵ Katoh, Y.⁶ Bannai, S.⁷ Yamamoto, M.⁸

2
- 0037569694
- E. Balogun, M. Hoque, P. Gong, E. Killeen, C. J. Green, R. Foresti, J. Alam, R. Motterlini, Biochem. J. 2003, 371, 887-895.
- (2003) Biochem. J. , vol.371 , pp. 887-895
- Balogun, E.¹ Hoque, M.² Gong, P.³ Killeen, E.⁴ Green, C.J.⁵ Foresti, R.⁶ Alam, J.⁷ Motterlini, R.⁸

3
- 33645945014
- S. W. Ryter, J. Alam, A. M. Choi, Physiol. Rev. Phys. 2006, 86, 583-650.
- (2006) Physiol. Rev. Phys. , vol.86 , pp. 583-650
- Ryter, S.W.¹ Alam, J.² Choi, A.M.³

4
- 0344284580
- L. E. Otterbein, B. S. Zuckerbraun, M. Haga, F. Liu, R. Song, A. Usheva, C. Stachulak, N. Bodyak, R. N. Smith, E. Csizmadia, S. Tyagi, Y. Akamatsu, R. J. Flavell, T. R. Billiar, E. Tzeng, F. H. Bach, A. M. Choi, M. P. Soares, Nature Med. 2003, 9, 183-190.
- (2003) Nature Med. , vol.9 , pp. 183-190
- Otterbein, L.E.¹ Zuckerbraun, B.S.² Haga, M.³ Liu, F.⁴ Song, R.⁵ Usheva, A.⁶ Stachulak, C.⁷ Bodyak, N.⁸ Smith, R.N.⁹ Csizmadia, E.¹⁰ Tyagi, S.¹¹ Akamatsu, Y.¹² Flavell, R.J.¹³ Billiar, T.R.¹⁴ Tzeng, E.¹⁵ Bach, F.H.¹⁶ Choi, A.M.¹⁷ Soares, M.P.¹⁸

5
- 4644251110
- J. K. Sarady, B. S. Zuckerbraun, M. Bilban, O. Wagner, A. Usheva, F. Liu, E. Ifedigbo, R. Zamora, A. M. Choi, L. E. Otterbein, FASEB J. 2004, 18, 854-856.
- (2004) FASEB J. , vol.18 , pp. 854-856
- Sarady, J.K.¹ Zuckerbraun, B.S.² Bilban, M.³ Wagner, O.⁴ Usheva, A.⁵ Liu, F.⁶ Ifedigbo, E.⁷ Zamora, R.⁸ Choi, A.M.⁹ Otterbein, L.E.¹⁰

6
- 29144489192
- R. A. Hegazi, K. N. Rao, A. Mayle, A. R. Sepulveda, L. E. Otterbein, S. E. Plevy, J. Exp. Med. 2005, 202, 1703-1713.
- (2005) J. Exp. Med. , vol.202 , pp. 1703-1713
- Hegazi, R.A.¹ Rao, K.N.² Mayle, A.³ Sepulveda, A.R.⁴ Otterbein, L.E.⁵ Plevy, S.E.⁶

7
- 0037622140
- R. Motterlini, J. E. Clark, R. Foresti, P. Sarathchandra, B. E. Mann, C. J. Green, Circ. Res. 2002, 90, e17-e24.
- (2002) Circ. Res. , vol.90 , pp. e17-e24
- Motterlini, R.¹ Clark, J.E.² Foresti, R.³ Sarathchandra, P.⁴ Mann, B.E.⁵ Green, C.J.⁶

8
- 0041733077
- J. E. Clark, P. Naughton, S. Shurey, C. J. Green, T. R. Johnson, B. E. Mann, R. Foresti, R. Motterlini, Circ. Res. 2003, 93, e2-e8.
- (2003) Circ. Res. , vol.93 , pp. e2-e8
- Clark, J.E.¹ Naughton, P.² Shurey, S.³ Green, C.J.⁴ Johnson, T.R.⁵ Mann, B.E.⁶ Foresti, R.⁷ Motterlini, R.⁸

9
- 77956323967
- R. Motterlini, L. E. Otterbein, Nat. Rev. Drug Discovery 2010, 9, 728-743.
- (2010) Nat. Rev. Drug Discovery , vol.9 , pp. 728-743
- Motterlini, R.¹ Otterbein, L.E.²

10
- 84856145785
- A. Yabluchanskiy, P. Sawle, S. Homer-Vanniasinkam, C. J. Green, R. Foresti, R. Motterlini, Crit Care Med. 2012, 40, 544-552.
- (2012) Crit Care Med. , vol.40 , pp. 544-552
- Yabluchanskiy, A.¹ Sawle, P.² Homer-Vanniasinkam, S.³ Green, C.J.⁴ Foresti, R.⁵ Motterlini, R.⁶

11
- 81755178436
- M. Desmard, R. Foresti, D. Morin, M. Dagoussat, A. Berdeaux, E. Denamur, S. H. Crook, B. E. Mann, D. Scapens, P. Montravers, J. Boczkowski, R. Motterlini, Antioxid. Redox Signaling 2012, 16, 153-163.
- (2012) Antioxid. Redox Signaling , vol.16 , pp. 153-163
- Desmard, M.¹ Foresti, R.² Morin, D.³ Dagoussat, M.⁴ Berdeaux, A.⁵ Denamur, E.⁶ Crook, S.H.⁷ Mann, B.E.⁸ Scapens, D.⁹ Montravers, P.¹⁰ Boczkowski, J.¹¹ Motterlini, R.¹²

12
- 84865519011
- K. Kramkowski, A. Leszczynska, A. Mogielnicki, S. Chlopicki, A. Fedorowicz, E. Grochal, B. Mann, T. Brzoska, T. Urano, R. Motterlini, W. Buczko, Arterioscler. Thromb. Vasc. Biol. 2012, 32, 2149-2157.
- (2012) Arterioscler. Thromb. Vasc. Biol. , vol.32 , pp. 2149-2157
- Kramkowski, K.¹ Leszczynska, A.² Mogielnicki, A.³ Chlopicki, S.⁴ Fedorowicz, A.⁵ Grochal, E.⁶ Mann, B.⁷ Brzoska, T.⁸ Urano, T.⁹ Motterlini, R.¹⁰ Buczko, W.¹¹

13
- 13244291654
- R. Motterlini, P. Sawle, S. Bains, J. Hammad, R. Alberto, R. Foresti, C. J. Green, FASEB J. 2005, 19, 284-286.
- (2005) FASEB J. , vol.19 , pp. 284-286
- Motterlini, R.¹ Sawle, P.² Bains, S.³ Hammad, J.⁴ Alberto, R.⁵ Foresti, R.⁶ Green, C.J.⁷

14
- 84872329373
- R. Motterlini, P. Sawle, J. Hammad, B. E. Mann, T. R. Johnson, C. J. Green, R. Foresti, Pharmacol. Res. 2013, 68, 108-117.
- (2013) Pharmacol. Res. , vol.68 , pp. 108-117
- Motterlini, R.¹ Sawle, P.² Hammad, J.³ Mann, B.E.⁴ Johnson, T.R.⁵ Green, C.J.⁶ Foresti, R.⁷

15
- 79953737777
- S. H. Crook, B. E. Mann, J. A. H. M. Meijer, H. Adams, P. Sawle, D. Scapens, R. Motterlini, Dalton Trans. 2011, 40, 4230-4235.
- (2011) Dalton Trans. , vol.40 , pp. 4230-4235
- Crook, S.H.¹ Mann, B.E.² Meijer, J.A.H.M.³ Adams, H.⁴ Sawle, P.⁵ Scapens, D.⁶ Motterlini, R.⁷

16
- 67249154377
- A. J. Atkin, S. Williams, P. Sawle, R. Motterlini, J. M. Lynam, I. J. Fairlamb, Dalton Trans. 2009, 19, 3653-3656.
- (2009) Dalton Trans. , vol.19 , pp. 3653-3656
- Atkin, A.J.¹ Williams, S.² Sawle, P.³ Motterlini, R.⁴ Lynam, J.M.⁵ Fairlamb, I.J.⁶

17
- 36749076990
- L. S. Nobre, J. D. Seixas, C. C. Romao, L. M. Saraiva, Antimicrob. Agents Chemother. 2007, 51, 4303-4307.
- (2007) Antimicrob. Agents Chemother. , vol.51 , pp. 4303-4307
- Nobre, L.S.¹ Seixas, J.D.² Romao, C.C.³ Saraiva, L.M.⁴

18
- 84875151539
- R. Foresti, R. Motterlini, Future Med. Chem. 2013, 5, 367-369.
- (2013) Future Med. Chem. , vol.5 , pp. 367-369
- Foresti, R.¹ Motterlini, R.²

19
- 0034655773
- R. Motterlini, R. Foresti, R. Bassi, C. J. Green, Free Radical Biol. Med. 2000, 28, 1303-1312.
- (2000) Free Radical Biol. Med. , vol.28 , pp. 1303-1312
- Motterlini, R.¹ Foresti, R.² Bassi, R.³ Green, C.J.⁴

20
- 0036176259
- G. Scapagnini, R. Foresti, V. Calabrese, A. M. Giuffrida Stella, C. J. Green, R. Motterlini, Mol. Pharmacol. 2002, 61, 554-561.
- (2002) Mol. Pharmacol. , vol.61 , pp. 554-561
- Scapagnini, G.¹ Foresti, R.² Calabrese, V.³ Giuffrida Stella, A.M.⁴ Green, C.J.⁵ Motterlini, R.⁶

21
- 79952136166
- R. A. Linker, D. H. Lee, S. Ryan, A. M. van Dam, R. Conrad, P. Bista, W. Zeng, X. Hronowsky, A. Buko, S. Chollate, G. Ellrichmann, W. Bruck, K. Dawson, S. Goelz, S. Wiese, R. H. Scannevin, M. Lukashev, R. Gold, Brain 2011, 134, 678-692.
- (2011) Brain , vol.134 , pp. 678-692
- Linker, R.A.¹ Lee, D.H.² Ryan, S.³ Van Dam, A.M.⁴ Conrad, R.⁵ Bista, P.⁶ Zeng, W.⁷ Hronowsky, X.⁸ Buko, A.⁹ Chollate, S.¹⁰ Ellrichmann, G.¹¹ Bruck, W.¹² Dawson, K.¹³ Goelz, S.¹⁴ Wiese, S.¹⁵ Scannevin, R.H.¹⁶ Lukashev, M.¹⁷ Gold, R.¹⁸

22
- 84863244462
- H. Ashrafian, G. Czibik, M. Bellahcene, D. Aksentijevic, A. C. Smith, S. J. Mitchell, M. S. Dodd, J. Kirwan, J. J. Byrne, C. Ludwig, H. Isackson, A. Yavari, N. B. Stottrup, H. Contractor, T. J. Cahill, N. Sahgal, D. R. Ball, R. I. Birkler, I. Hargreaves, D. A. Tennant, J. Land, C. A. Lygate, M. Johannsen, R. K. Kharbanda, S. Neubauer, C. Redwood, R. de Cabo, I. Ahmet, M. Talan, U. L. Gunther, A. J. Robinson, M. R. Viant, P. J. Pollard, D. J. Tyler, H. Watkins, Cell Metab. 2012, 15, 361-371.
- (2012) Cell Metab. , vol.15 , pp. 361-371
- Ashrafian, H.¹ Czibik, G.² Bellahcene, M.³ Aksentijevic, D.⁴ Smith, A.C.⁵ Mitchell, S.J.⁶ Dodd, M.S.⁷ Kirwan, J.⁸ Byrne, J.J.⁹ Ludwig, C.¹⁰ Isackson, H.¹¹ Yavari, A.¹² Stottrup, N.B.¹³ Contractor, H.¹⁴ Cahill, T.J.¹⁵ Sahgal, N.¹⁶ Ball, D.R.¹⁷ Birkler, R.I.¹⁸ Hargreaves, I.¹⁹ Tennant, D.A.²⁰ more..

23
- 84883412049
- R. Foresti, S. K. Bains, T. S. Pitchumony, L. E. de Castro Bras, F. Drago, J. L. Dubois-Rande, C. Bucolo, R. Motterlini, Pharmacol. Res. 2013, 76, 132-148.
- (2013) Pharmacol. Res. , vol.76 , pp. 132-148
- Foresti, R.¹ Bains, S.K.² Pitchumony, T.S.³ De Castro Bras, L.E.⁴ Drago, F.⁵ Dubois-Rande, J.L.⁶ Bucolo, C.⁷ Motterlini, R.⁸

24
- 84898831795
- C. B. Burness, E. D. Deeks, CNS Drugs 2014, 28, 373-387.
- (2014) CNS Drugs , vol.28 , pp. 373-387
- Burness, C.B.¹ Deeks, E.D.²

25
- 84915819052
- Chem. Eur. J. 2014, 20, 14698-14704
- (2014) Chem. Eur. J. , vol.20 , pp. 14698-14704

26
- 49049110697
- P. Sawle, B. E. Moulton, M. Jarzykowska, C. J. Green, R. Foresti, I. J. Fairlamb, R. Motterlini, Chem. Res. Toxicol. 2008, 21, 1484-1494.
- (2008) Chem. Res. Toxicol. , vol.21 , pp. 1484-1494
- Sawle, P.¹ Moulton, B.E.² Jarzykowska, M.³ Green, C.J.⁴ Foresti, R.⁵ Fairlamb, I.J.⁶ Motterlini, R.⁷

27
- 33947462628
- H. Greenfield, H. W. Sternberg, R. A. Friedel, J. H. Wotiz, R. Markby, I. Wender, J. Am. Chem. Soc. 1956, 78, 120-124.
- (1956) J. Am. Chem. Soc. , vol.78 , pp. 120-124
- Greenfield, H.¹ Sternberg, H.W.² Friedel, R.A.³ Wotiz, J.H.⁴ Markby, R.⁵ Wender, I.⁶

28
- 42549112220
- I. Ott, B. Kircher, R. Dembiski, R. Gust, Expert Opin. Ther. Pat. 2008, 18, 327-337.
- (2008) Expert Opin. Ther. Pat. , vol.18 , pp. 327-337
- Ott, I.¹ Kircher, B.² Dembiski, R.³ Gust, R.⁴

29
- 54949104365
- G.-Y. Shi, C.-Y. Pan, Macromol. Rapid Commun. 2008, 29, 1672-1678.
- (2008) Macromol. Rapid Commun. , vol.29 , pp. 1672-1678
- Shi, G.-Y.¹ Pan, C.-Y.²

30
- 84866666959
- B. W. Michel, A. R. Lippert, C. J. Chang, J. Am. Chem. Soc. 2012, 134, 15668-15671.
- (2012) J. Am. Chem. Soc. , vol.134 , pp. 15668-15671
- Michel, B.W.¹ Lippert, A.R.² Chang, C.J.³

31
- 79957491717
- A. J. Atkin, J. M. Lynam, B. E. Moulton, P. Sawle, R. Motterlini, N. M. Boyle, M. T. Pryce, I. J. Fairlamb, Dalton Trans. 2011, 40, 5755-5761.
- (2011) Dalton Trans. , vol.40 , pp. 5755-5761
- Atkin, A.J.¹ Lynam, J.M.² Moulton, B.E.³ Sawle, P.⁴ Motterlini, R.⁵ Boyle, N.M.⁶ Pryce, M.T.⁷ Fairlamb, I.J.⁸

32
- 0035966451
- M. L. Marcos, M. J. Macazaga, R. M. Medina, C. Moreno, J. A. Castro, J. L. Gomez, S. Delgado, J. Gonzalez-Velasco, Inorg. Chim. Acta 2001, 312, 249-255.
- (2001) Inorg. Chim. Acta , vol.312 , pp. 249-255
- Marcos, M.L.¹ Macazaga, M.J.² Medina, R.M.³ Moreno, C.⁴ Castro, J.A.⁵ Gomez, J.L.⁶ Delgado, S.⁷ Gonzalez-Velasco, J.⁸

33
- 84881223660
- A. M. Gomez-Marin, J. P. Hernandez-Ortiz, J. Phys. Chem. 2014, 117, 15716-15727.
- (2014) J. Phys. Chem. , vol.117 , pp. 15716-15727
- Gomez-Marin, A.M.¹ Hernandez-Ortiz, J.P.²

34
- 81855164828
- S. Balasubramanian, B. Lakshmanan, C. E. Hetzke, V. A. Sethuraman, J. W. Weidner, Electrochim. Acta 2011, 58, 723-728.
- (2011) Electrochim. Acta , vol.58 , pp. 723-728
- Balasubramanian, S.¹ Lakshmanan, B.² Hetzke, C.E.³ Sethuraman, V.A.⁴ Weidner, J.W.⁵

35
- 10044224161
- D. Osella, L. Milone, C. Nervi, M. Ravera, J. Organomet. Chem. 1995, 488, 1-7.
- (1995) J. Organomet. Chem. , vol.488 , pp. 1-7
- Osella, D.¹ Milone, L.² Nervi, C.³ Ravera, M.⁴

36
- 77951938927
- A. Thiessen, M. M. Schmidt, R. Dringen, Neurosci. Lett. 2010, 475, 56-60.
- (2010) Neurosci. Lett. , vol.475 , pp. 56-60
- Thiessen, A.¹ Schmidt, M.M.² Dringen, R.³

37
- 84893104809
- Y. Tayem, C. J. Green, R. Motterlini, R. Foresti, Pharmacol. Res. 2014, 81, 1-9.
- (2014) Pharmacol. Res. , vol.81 , pp. 1-9
- Tayem, Y.¹ Green, C.J.² Motterlini, R.³ Foresti, R.⁴

38
- 54149116366
- L. Kappos, R. Gold, D. H. Miller, D. G. Macmanus, E. Havrdova, V. Limmroth, C. H. Polman, K. Schmierer, T. A. Yousry, M. Yang, M. Eraksoy, E. Meluzinova, I. Rektor, K. T. Dawson, A. W. Sandrock, G. N. O'Neill, Lancet 2008, 372, 1463-1472.
- (2008) Lancet , vol.372 , pp. 1463-1472
- Kappos, L.¹ Gold, R.² Miller, D.H.³ Macmanus, D.G.⁴ Havrdova, E.⁵ Limmroth, V.⁶ Polman, C.H.⁷ Schmierer, K.⁸ Yousry, T.A.⁹ Yang, M.¹⁰ Eraksoy, M.¹¹ Meluzinova, E.¹² Rektor, I.¹³ Dawson, K.T.¹⁴ Sandrock, A.W.¹⁵ O'Neill, G.N.¹⁶

39
- 80053951690
- S. Romanski, B. Kraus, U. Schatzschneider, J. M. Neudorfl, S. Amslinger, H. G. Schmalz, Angew. Chem. 2011, 123, 2440-2444;
- (2011) Angew. Chem. , vol.123 , pp. 2440-2444
- Romanski, S.¹ Kraus, B.² Schatzschneider, U.³ Neudorfl, J.M.⁴ Amslinger, S.⁵ Schmalz, H.G.⁶

40
- 79952053626
- Angew. Chem. Int. Ed. 2011, 50, 2392-2396.
- (2011) Angew. Chem. Int. Ed. , vol.50 , pp. 2392-2396

41
- 83455236753
- F. Zobi, O. Blacque, R. A. Jacobs, M. C. Schaub, A. Y. Bogdanova, Dalton Trans. 2012, 41, 370-378.
- (2012) Dalton Trans. , vol.41 , pp. 370-378
- Zobi, F.¹ Blacque, O.² Jacobs, R.A.³ Schaub, M.C.⁴ Bogdanova, A.Y.⁵

42
- 79551692596
- T. Santos-Silva, A. Mukhopadhyay, J. D. Seixas, G. J. Bernardes, C. C. Romao, M. J. Romao, J. Am. Chem. Soc. 2011, 133, 1192-1195.
- (2011) J. Am. Chem. Soc. , vol.133 , pp. 1192-1195
- Santos-Silva, T.¹ Mukhopadhyay, A.² Seixas, J.D.³ Bernardes, G.J.⁴ Romao, C.C.⁵ Romao, M.J.⁶

43
- 33747609353
- M. G. Bani-Hani, D. Greenstein, B. E. Mann, C. J. Green, R. Motterlini, J. Pharmacol. Exp. Ther. 2006, 318, 1315-1322.
- (2006) J. Pharmacol. Exp. Ther. , vol.318 , pp. 1315-1322
- Bani-Hani, M.G.¹ Greenstein, D.² Mann, B.E.³ Green, C.J.⁴ Motterlini, R.⁵

44
- 0035200007
- R. Foresti, H. Goatly, C. J. Green, R. Motterlini, Am. J. Physiol Heart Circ. Physiol. 2001, 281, H1976-H1984.
- (2001) Am. J. Physiol Heart Circ. Physiol. , vol.281 , pp. H1976-H1984
- Foresti, R.¹ Goatly, H.² Green, C.J.³ Motterlini, R.⁴

45
- 0031722008
- M. J. J. Vesely, D. J. Exon, J. E. Clark, R. Foresti, C. J. Green, R. Motterlini, Am. J. Physiol. 1998, 275, C1087-C1094.
- (1998) Am. J. Physiol. , vol.275 , pp. C1087-C1094
- Vesely, M.J.J.¹ Exon, D.J.² Clark, J.E.³ Foresti, R.⁴ Green, C.J.⁵ Motterlini, R.⁶

46
- 23044459608
- P. Sawle, R. Foresti, B. E. Mann, T. R. Johnson, C. J. Green, R. Motterlini, Br. J. Pharmacol. 2005, 145, 800-810.
- (2005) Br. J. Pharmacol. , vol.145 , pp. 800-810
- Sawle, P.¹ Foresti, R.² Mann, B.E.³ Johnson, T.R.⁴ Green, C.J.⁵ Motterlini, R.⁶

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