Assessment of the safety, targeting, and distribution characteristics of a novel pH-sensitive hydrogel

Colloids and Surfaces B: Biointerfaces

Volumn 123, Issue , 2014, Pages 965-973

  Dong, Kai ^a   Dong, Yalin ^a   You, Cuiyu ^a   Xu, Wei ^a   Huang, Xiaoyan ^a   Yan, Yan ^a   Zhang, Lu ^a   Wang, Ke ^a   Xing, Jianfeng ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Acute toxicity; Cytotoxicity; PH sensitive hydrogel; Pharmacokinetics study

Indexed keywords

BLOOD; COPOLYMERS; CYTOTOXICITY; DIGESTIVE SYSTEM; DRUG DELIVERY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PH SENSORS; PHARMACOKINETICS; RATS; TISSUE; TOXICITY;

ACUTE TOXICITY; CELL VIABILITY ASSAYS; DEXAMETHASONES; DISTRIBUTION CHARACTERISTICS; PH-SENSITIVE HYDROGEL; SERUM CHEMISTRY; TARGETED DRUG DELIVERY; TISSUE DISTRIBUTIONS;

HYDROGELS;

COPOLYMER; DEXAMETHASONE; GLYCIDYL METHACRYLATE; METHACRYLIC ACID; POLOXAMER; POLYCAPROLACTONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CELL VIABILITY ASSAY; COLON; CONTROLLED STUDY; CYTOTOXICITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG MECHANISM; FEMALE; HEK293 CELL LINE; HUMAN; HUMAN CELL; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; MALE; MOUSE; NONHUMAN; PH; RAT; TISSUE DISTRIBUTION; TOXICITY TESTING;

EID: 84915818552     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2014.10.049     Document Type: Article

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