A reversibly antigen-responsive hydrogen

Nature

Volumn 399, Issue 6738, 1999, Pages 766-768

  Miyata, Takashi ^a   Asami, Nokiro ^a   Uragani, Tadashi ^a  

^a KANSAI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; CHEMICAL BONDS; COMPOSITION EFFECTS; CROSSLINKING; GRAFT COPOLYMERS; GRAFTING (CHEMICAL); INTELLIGENT MATERIALS; MECHANICAL PERMEABILITY; SHAPE MEMORY EFFECT;

REVERSIBLY ANTIGEN-RESPONSIVE HYDROGEL;

HYDROGELS;

ACRYLAMIDE; ANTIBODY; ANTIGEN; IMMUNOGLOBULIN G; N,N' METHYLENEBISACRYLAMIDE; POLYMER; SOLVENT; VINYL DERIVATIVE;

ARTICLE; CROSS LINKING; HYDROGEL; POLYMERIZATION; PRIORITY JOURNAL;

ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; ANTIGENS; BIOPOLYMERS; CHEMISTRY, PHYSICAL; CROSS-LINKING REAGENTS; GOATS; HYDROGELS; IMMUNOGLOBULIN G; RABBITS;

EID: 0033600290     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/21619     Document Type: Article

References (26)

1. Tanaka, T. Collapse of gels and the critical endpoint. Phys. Rev. Lett. 40, 820-823 (1978).
2. Tanaka, T. et al. Phase transitions in ionic gels. Phys. Rev. Lett. 45, 1636-1639 (1980).
3. Siegel, R. A. & Firestone, B. A. pH-dependent equilibrium swelling properties of Hydrophobic polyelectrolyte copolymer gels. Macromoleculcs 21, 3254-3259 (1988).
4. Hirokawa, Y. & Tanaka, T. Volume phase transition in a nonionic gel. J. Chem. Phys. 81, 6379-6380 (1984).
5. Hoffman, A. S. Applications of thermally reversible polymers and hydrogels in therapeutics and diagnostics. J. Controlled Release 6, 297-305 (1987).
6. Bae, Y. H., Okano, T., Hsu, R. & Kim, S. W. Thermo-sensitive polymers as on-off switches for drug release. Makromol. Chem. Rapid Commun. 8, 481-485 (1987).
7. Bae, Y. H., Okano, T. & Kim, S. W. A new thermo-sensitive hydrogel: interpenetrating polymer networks from N-acryloylpyrrolidine and poly(oxyethylene). Makromol. Chem. Rapid Commun. 9, 185-189 (1988).
8. Chen, G. & Hoffman, A. S. Graft copolymers that exhibit temperature-induced phase transitions over a wide range of pH. Natare 373, 49-52 (1995).
9. Yoshida, R. et al. Comb-type grafted hydrogels with rapid de-swelling response to temperature changes. Nature 374, 240-242 (1995).
10. Miyata, T., Nakamae, K., Hoffman, A. S. & Kanzaki, Y. Stimuli-sensitivities of hydrogels containing phosphate groups. Macromol. Chem. Phys. 195, 1111-1120 (1994).
11. Aoki, T. et al. Temperature-responsive interpenetrating polymer networks constructed with poly(acrylic acid) and poly(N,N-dimethylacrylamide). Macromolecules 27, 947-952 (1994).
12. Stayton, P. S. et al. Control of protein-ligand recognition using a stimuli-responsive polymer. Nature 378, 472-474 (1995).
13. Feil, H., Bae, Y. H., Feijen, J. & Kim, S. W. Molecular separation by thermosensitive hydrogel membranes. J. Membrane Sci. 64, 283-294 (1991).
14. Tanaka, T., Nishio, I., Sun, S.-T. & Ueno-Nishio, S. Collapse of gels in an electric field. Science 218, 467-469 (1982).
15. Kwon, I. C., Bae, Y. H. & Kim, S. W. Electrically erodible polymer gel for controlled release of drugs. Nature 354, 291-293 (1991).
16. Osada, Y., Okuzaki, H. & Hori, H. A polymer gel with electrically driven motility. Nature 355, 242-244 (1992).
17. Kokufuta, E., Zhang, Y.-Q. & Tanaka, T. Saccharide-sensitive phase transition of a lectin-loaded gel Nature 351, 302-304 (1991).
18. Miyata, T., Jikihara, A., Nakamae, K. & Hoffman, A. S. Preparation of poly(glucosyloxyethyl methacrylate)-concanavalin A complex hydrogel and its glucose-sensitivity. Macromol. Chem. Phys. 197, 1135-1146 (1996).
19. Lee, S. J. & Park, K. Synthesis and characterization of sol-gel phase-rever̀sible hydrogels sensitive to glucose. J. Mol. Recogn. 9, 549-557 (1996).
20. Obidat, A. A. & Park, K. Characterization of glucose dependent gel-sol phase transition of polymeric glucose-concanavalin A hydrogel system. Pharm. Res. 13, 929-995 (1996).
21. Obidat, A. A. & Park, K. Characterization of protein release through glucose-sensitive hydrogel membranes. Biomaterials 18, 801-806 (1997).
22. Kataoka, K. et al. Totally synthetic polymer gels responding to external glucose concentration: their preparation and application to on-off regulation of insulin release. J. Am. Chem. Soc. 120, 12694-12695 (1998).
23. Shoemaker, S. G., Hoffman, A. S. & Priest, J. H. Synthesis and properties of vinyl monomer/enzyme conjugates. Appl. Biochem. Biotech. 15, 11-24 (1987).
24. Natsume, T. et al. Interactions between collagen-binding stress protein HSP47 and collagen. J. Biol. Chem. 269, 31224-31228 (1994).
25. Murai, N., Taguchi, H. & Yoshida, M. Kinetic analysis of interactions between GroEL and reduced α-lactalbumin. J. Biol. Chem. 270, 19957-19963 (1995).
26. Flory, P. J. Principle of Polymer Chemistry (Cornell Univ. Press, New York, 1953).