Further insights into the pharmacology of the human trace amine-associated receptors: Discovery of novel Ligands for taar1 by a virtual screening approach

Chemical Biology and Drug Design

Volumn 84, Issue 6, 2014, Pages 712-720

  Cichero, Elena ^a   Espinoza, Stefano ^b   Franchini, Silvia ^c   Guariento, Sara ^a   Brasili, Livio ^c   Gainetdinov, Raul R ^b,d,e   Fossa, Paola ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^c UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^d SKOLKOVO INSTITUTE OF SCIENCE AND TECHNOLOGY   (Russian Federation)

^e ST PETERSBURG STATE UNIVERSITY   (Russian Federation)

Author keywords

G protein coupled receptor; TAAR 1 receptor; Virtual screening approach

Indexed keywords

1,3 DIOXOLANE DERIVATIVE; 1,3 DITHIOLANE DERIVATIVE; 1,3 OXATHIOLANE DERIVATIVE; 1,4 DIOXANE DERIVATIVE; 3 IODOTHYRONAMINE; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; CYCLOPENTANOL; CYCLOPENTANONE DERIVATIVE; G PROTEIN COUPLED RECEPTOR; PENTANOL; RO 5166017; SPIRODIOXOLANE; TETRAHYDROFURAN DERIVATIVE; THYROID HORMONE DERIVATIVE; TRACE AMINE ASSOCIATED RECEPTOR 1; UNCLASSIFIED DRUG; LIGAND; OXAZOLE DERIVATIVE; PHENETHYLAMINE DERIVATIVE; PROTEIN BINDING; RO5166017; TRACE AMINE-ASSOCIATED RECEPTOR 1;

ARTICLE; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; DRUG SCREENING; DRUG STRUCTURE; HUMAN; HYDROGEN BOND; IN VITRO STUDY; PROTEIN TARGETING; RECEPTOR BINDING; AGONISTS; ANTAGONISTS AND INHIBITORS; BINDING SITE; CHEMICAL DATABASE; CHEMISTRY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEK293 CELL LINE; METABOLISM; MOLECULAR DOCKING; PROTEIN TERTIARY STRUCTURE;

BINDING SITES; DATABASES, CHEMICAL; DRUG EVALUATION, PRECLINICAL; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEK293 CELLS; HUMANS; LIGANDS; MOLECULAR DOCKING SIMULATION; OXAZOLES; PHENETHYLAMINES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84915779395     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/cbdd.12367     Document Type: Article

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