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Volumn 4, Issue 3, 2009, Pages 393-399

1,3-Dioxolane-based ligands as rigid analogues of naftopidil: Structure-affinity/activity relationships at α1 and 5-HT 1A receptors

(10) Sorbi, Claudia a Franchini, Silvia a Tait, Annalisa a Prandi, Adolfo a Gallesi, Rossella a Angeli, Piero b Marucci, Gabriella b Pirona, Lorenza c Poggesi, Elena c Brasili, Livio a

a UNIVERSITY OF MODENA AND REGGIO EMILIA (Italy)

b UNIVERSITY OF CAMERINO (Italy)

c Recordati SpA (Italy)

Author keywords

1 adrenoceptors; 1,3 dioxolane; 5 HT1A receptors; Biological activity; Structure activity relationships

Indexed keywords

1,3 DIOXOLANE DERIVATIVE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; ALPHA 1 ADRENERGIC RECEPTOR; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; NAFTOPIDIL; NAFTOPIDIL DERIVATIVE; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; HUMAN; HUMAN CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; DIOXOLANES; HELA CELLS; HUMANS; LIGANDS; MALE; NAPHTHALENES; PIPERAZINES; PROTEIN BINDING; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTORS, ADRENERGIC, ALPHA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 62749161482 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.200800277 Document Type: Article

Times cited : (36)

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