A novel dysregulated pathway-identification analysis based on global influence of within-pathway effects and crosstalk between pathways

Journal of the Royal Society Interface

Volumn 12, Issue 102, 2015, Pages

  Han, Junwei ^a   Li, Chunquan ^a   Yang, Haixiu ^a   Xu, Yanjun ^a   Zhang, Chunlong ^a   Ma, Jiquan ^a   Shi, Xinrui ^a   Liu, Wei ^a,b   Shang, Desi ^a   Yao, Qianlan ^a   Zhang, Yunpeng ^a   Su, Fei ^a   Feng, Li ^a   Li, Xia ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b HEILONGJIANG INSTITUTE OF TECHNOLOGY   (China)

Author keywords

Dysregulated pathway identification; Global influence; Pathway crosstalk; Random walk

Indexed keywords

CROSSTALK; DISEASES; DISTRIBUTION FUNCTIONS; RANDOM PROCESSES; SOCIAL NETWORKING (ONLINE);

CUMULATIVE DISTRIBUTION FUNCTION; DIFFERENTIAL EXPRESSIONS; GENE SET ENRICHMENT ANALYSIS; GLOBAL INFLUENCE; IDENTIFICATION METHOD; PATHWAY IDENTIFICATION; RANDOM WALK; RANDOM WALK WITH RESTART;

GENE EXPRESSION;

MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; RETINOID X RECEPTOR; INSULIN;

ALGORITHM; ANALYTIC METHOD; APOPTOSIS; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER GROWTH; CONTROLLED STUDY; DATA BASE; EXTRACELLULAR MATRIX; FATTY ACID METABOLISM; FEMALE; FOCAL ADHESION; GENE EXPRESSION; GENE INTERACTION; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; INFORMATION PROCESSING; LUNG CANCER; METASTASIS POTENTIAL; PATHWAY ANALYSIS BASED ON GLOBAL INFLUENCE; PROSTATE CANCER; SIGNAL TRANSDUCTION; THYROID CANCER; TRYPTOPHAN METABOLISM; WNT SIGNALING PATHWAY; BIOLOGICAL MODEL; BIOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETIC DATABASE; GENETICS; INTERNET; METABOLISM; NEOPLASM; PROCEDURES;

ALGORITHMS; COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; HUMANS; INSULIN; INTERNET; MODELS, BIOLOGICAL; NEOPLASMS; SIGNAL TRANSDUCTION;

EID: 84915750639     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2014.0937     Document Type: Article

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