Gene expression patterns distinguish breast carcinomas from normal breast tissues: The Malaysian context

Pathology Research and Practice

Volumn 206, Issue 4, 2010, Pages 223-228

  Pau Ni, Ivyna Bong ^a   Zakaria, Zubaidah ^a   Muhammad, Rohaizak ^b   Abdullah, Norlia ^b   Ibrahim, Naqiyah ^b   Aina Emran, Nor ^c   Hisham Abdullah, Nor ^d   Syed Hussain, Sharifah Noor Akmal ^b  

^a INSTITUTE FOR MEDICAL RESEARCH   (Malaysia)

^b DEPARTMENT OF PHARMACOLOGY   (Malaysia)

^c HOSPITAL KUALA LUMPUR   (Malaysia)

^d PUTRAJAYA HOSPITAL   (Malaysia)

Author keywords

Breast carcinomas; Differentially expressed genes; Gene expression

Indexed keywords

BETA GLOBIN; CD24 ANTIGEN; CD36 ANTIGEN; CD9 ANTIGEN; EPITHELIAL CELL ADHESION MOLECULE; GENE PRODUCT; LEPTIN; LIPOPROTEIN LIPASE; PROTEIN AKR1C1; PROTEIN AKR1C2; PROTEIN AKR1C3; TRANSCRIPTOME; TUMOR ASSOCIATED CALCIUM SIGNAL TRANSDUCER 2; TUMOR MARKER; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BREAST CARCINOGENESIS; BREAST CARCINOMA; BREAST EPITHELIUM; CANCER GENETICS; CANCER GROWTH; CHINESE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; HUMAN; HUMAN TISSUE; INDIAN; MALAYSIA;

BREAST; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALAYSIA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 77950867279     PISSN: 03440338     EISSN: 16180631     Source Type: Journal    
DOI: 10.1016/j.prp.2009.11.006     Document Type: Article

References (27)

1. Charpentier A., Aldaz C.M. The molecular basis of breast carcinogenesis. The Molecular Basis of Human Cancer 2002, 347-363. Human Press, Totowa, NJ. W.B. Coleman, G.J. Tsongalis (Eds.).
2. Kaipparettu B.A., Malik S., Konduri S.D., Liu W., Rokavec M., van der Kuip H., Hoppe R, Hammerich-Hille S., Fritz P., Schroth W., Abele I., Das G.M., Oesterreich S., Brauch H. Estrogen-mediated downregulation of CD24 in breast cancer cells. Cancer Cell Biol. 2008, 123(1):66-72.
3. Heintel D., Kienle D., Shehata M., Kröber A., Kroemer E., Schwarzinger I., Mitteregger D., Le T., Gleiß A., Mannhalter C., Chott A., Schwarzmeier J., Fonatsch C., Gaiger A., Döhner H., Stilgenbauer S., Jäger U. Chronic lymphocytic leukemia and normal B cells. High expression of lipoprotein lipase in poor risk B-cell chronic lymphocytic leukemia. Leukemia 2005, 19:1216-1223.
4. Roy D., Calaf G., Hei T.K. Allelic imbalance at 11p15.5-15.4 correlated with c-Ha-ras mutation during radiation-induced neoplastic transformation of human breast epithelial cells. Int. J. Cancer 2003, 103:730-737.
5. Sagiv E., Arber N. The novel oncogene CD24 and its arising role in the carcinogenesis of the GI tract: from research to therapy. Expert Rev. Gastroenterol. Hepatol. 2008, 2(1):125-133.
6. Kristiansen G., Winzer K-J., Mayordomo E., Bellach J., Schluns K., Denkert C., Dahl E., Pilarsky C., Altevogt P., Guski H., Dietel M. CD24 expression is a new prognostic marker in breast cancer. Clin. Cancer Res. 2003, 9:4906-4913.
7. Spizzo G., Gastl G., Wolf D., Gunsilius E., Steurer M., Fong D., Amberger A., Margreiter R., Obrist P. Correlation of COX-2 and Ep-CAM overexpression in human invasive breast cancer and its impact on survival. Br. J. Cancer 2003, 88(4):574-578.
8. Cancer incidence in Peninsular Malaysia, 2003-2005 2008, National Cancer Registry, Malaysia. G.C.C. Lim, S. Rampal, H. Yahaya (Eds.).
9. Uray I.P., Liang Y., Hyder S.M. Estradiol down-regulates CD36 expression in human breast cancer cells. Cancer Lett. 2004, 207(1):101-107.
10. Kim J.W., Cheng Y., Liu W., Li T., Yegnasubramanian S., Zheng S.L., Xu J., Isaacs W.B., Chang B-L. Genetic and epigenetic inactivation of LPL gene in human prostate cancer. Int. J. Cancer 2008, 124(3):734-738.
11. Snoussi K., Strosberg A.D., Bouaouina N., Ben Ahmed S., Helal A.N., Chouchane L. Leptin and leptin receptor polymorphisms are associated with increased risk and poor prognosis of breast carcinoma. BMC Cancer 2006, 6:38.
12. Yee K.O., Connolly C.M., Duquette M., Kazerounian S., Washington R., Lawler J. The effect of thrombospondin-1 on breast cancer metastasis. Breast Cancer Res. Treatment 2009, 114(1):85-96.
13. Münz M., Kieu C., Mack B., Schmitt B., Zeidler R., Gires O. The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation. Oncogene 2004, 23(34):5748-5758.
14. Münz M., Zeidler R., Gires O. The tumour-associated antigen EpCAM upregulates the fatty acid binding protein E-FABP. Cancer Lett. 2005, 225(1):151-157.
15. Onda M., Akaishi J., Asaka S., Okamoto J., Miyamoto S., Mizutani K., Yoshida A., Ito K., Emi M. Decreased expression of haemoglobin beta (HBB) gene in anaplastic thyroid cancer and recovery of its expression inhibits cell growth. Br. J. Cancer 2005, 92:2216-2224.
16. Schiebe M., Ohneseit P., Hoffmann W., Meyermann R., Rodemann H.P., Bamberg M. Loss of heterozygosity at 11p15 and p53 alterations in malignant gliomas. J. Cancer Res. Clin. Oncol. 2001, 127:325-328.
17. Thomassen M., Tan Q., Kruse T.A. Gene expression meta-analysis identifies chromosomal regions and candidate genes involved in breast cancer metastasis. Breast Cancer Res. Treatment 2009, 113(2):239-249.
18. Lewis M.J., Wiebe J.P., Heathcote J.G. Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma. BMC Cancer 2004, 4:27.
19. Namba R., Maglione J.E., Young L.J.T., Borowsky A.D., Cardiff R.D., MacLeod C.L., Gregg J.P. Molecular characterization of the transition to malignancy in a genetically engineered mouse-based model of ductal carcinoma In situ. Mol. Cancer Res. 2004, 2:453-463.
20. Sørlie T., Perou C.M., Tibshirani R., Aas T., Geisler S., Johnsen H., Hastie T., Eisen M.B., van de Rijn M., Jeffrey S.S., Thorsen T., Quist H., Matese J.C., Brown P.O., Botstein D., Eystein Lønning P., Børresen-Dale A.L. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. PNAS 2001, 98(19):10869-10874.
21. Sørlie T., Tibshirani R., Parker J., Hastie T., Marron J.S., Nobel A., Deng S., Johnsen H., Pesich R., Geisler S., Demeter J., Perou C.M., Lønning P.E., Brown P.O., Børresen-Dale A.L., Botstein D. Repeated observation of breast tumor subtypes in independent gene expression data sets. PNAS 2003, 100:8418-8423.
22. Launonen V., Mannermaa A., Stenback F., Kosma V.M., Puistola U., Huusko P., Anttila M., Bloigu R., Saarikoski S., Kauppila A., Winqvist R. Loss of heterozygosity at chromosomes 3, 6, 8, 11, 16, and 17 in ovarian cancer: correlation to clinicopathological variables. Cancer Genet. Cytogenet. 2000, 122:49-54.
23. Shi W., Fan H., Shum L., Derynck R. The Tetraspanin Cd9 Associates with transmembrane TGF-α and regulates TGF-α-induced Egf receptor activation and cell proliferation. J. Cell Biol. 2000, 148(3):591-602.
24. Osta W.A., Chen Y., Mikhitarian K., Mitas M., Salem M., Hannun Y.A., Cole D.J., Gillanders W.E. EpCAM is overexpressed in breast cancer and is a potential target for breast cancer gene therapy. Cancer Res. 2004, 64(16):5818-5824.
25. Hsiao W-C., Young K-C., Lin S-L., Lin P-W. Estrogen receptor-α polymorphism in a Taiwanese clinical breast cancer population: a case-control study. Breast Cancer Res. 2004, 6(3):R180-R186.
26. Hu X., Juneja S.C., Maihle N.J., Cleary M.P. Leptin - a growth factor in normal and malignant breast cells and for normal mammary gland development. J. Natl. Cancer I 2002, 94(22):1704-1711.
27. Xu X.L., Wu L.C., Du F., Davis A., Peyton M., Tomizawa Y., Maitra A., Tomlinson G., Gazdar A.F., Weissman B.E., Bowcock A.M., Baer R., Minna J.D. Inactivation of human SRBC, located within the 11p15.5-p15.4 tumor suppressor region, in breast and lung cancers. Cancer Res. 2001, 61:7943-7949.