Lithium, but not fluoxetine or the corticotropin-releasing factor receptor 1 receptor antagonist R121919, increases cell proliferation in the adult dentate gyrus

Journal of Pharmacology and Experimental Therapeutics

Volumn 337, Issue 1, 2011, Pages 180-186

  Hanson, Nicola D ^a   Nemeroff, Charles B ^b   Owens, Michael J ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (6 DIMETHYLAMINO 4 METHYL 3 PYRIDINYL) 7 DIPROPYLAMINO 2,5 DIMETHYLPYRAZOLO[1,5 A]PYRIMIDINE; BRAIN DERIVED NEUROTROPHIC FACTOR; FLUOXETINE; LITHIUM CARBONATE; MESSENGER RNA; PALIPERIDONE;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL PROLIFERATION; CELL SURVIVAL; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DENTATE GYRUS; DRUG BLOOD LEVEL; DRUG COMPETITION; DRUG EFFECT; LONG TERM CARE; MALE; MONOTHERAPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

AGE FACTORS; ANIMALS; CELL PROLIFERATION; DENTATE GYRUS; FLUOXETINE; LITHIUM; MALE; PILOT PROJECTS; PYRIMIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE;

EID: 79953016389     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.175372     Document Type: Article

References (42)

1. Alonso R, Griebel G, Pavone G, Stemmelin J, Le Fur G, and Soubrie P (2004) Blockade of CRF(1) or V(1b) receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression. Mol Psychiatry 9:278-286, 224. (Pubitemid 38496711)
2. Bessa JM, Ferreira D, Melo I, Marques F, Cerqueira JJ, Palha JA, Almeida OF, and Sousa N (2009) The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling. Mol Psychiatry 14:764-773, 739.
3. Bowden CL (2005) Atypical antipsychotic augmentation of mood stabilizer therapy in bipolar disorder. J Clin Psychiatry 66 (Suppl 3):12-19. Review.
4. Chen G, Rajkowska G, Du F, Seraji-Bozorgzad N, and Manji HK (2000) Enhancement of hippocampal neurogenesis by lithium. J Neurochem 75:1729-1734.
5. Cowen DS, Takase LF, Fornal CA, and Jacobs BL (2008) Age-dependent decline in hippocampal neurogenesis is not altered by chronic treatment with fluoxetine. Brain Res 1228:14-19.
6. David DJ, Samuels BA, Rainer Q, Wang JW, Marsteller D, Mendez I, Drew M, Craig DA, Guiard BP, Guilloux JP, et al. (2009) Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. Neuron 62:479-493.
7. Dayer AG, Ford AA, Cleaver KM, Yassaee M, and Cameron HA (2003) Short-term and long-term survival of new neurons in the rat dentate gyrus. J Comp Neurol 460:563-572. (Pubitemid 36528662)
8. Dremencov E, El Mansari M, Blier P (2007a) Distinct electrophysiological effects of paliperidone and risperidone on the firing activity of rat serotonin and norepinephrine neurons. Psychopharmacology (Berl) 194:63-72. (Pubitemid 47282734)
9. Dremencov E, El Mansari M, and Blier P (2007b) Noradrenergic augmentation of escitalopram response by risperidone: electrophysiologic studies in the rat brain. Biol Psychiatry 61:671-678. (Pubitemid 46328857)
10. Ghaemi SN and Goodwin FK (1999) Use of atypical antipsychotic agents in bipolar and schizoaffective disorders: review of the empirical literature. J Clin Psychopharmacol 19:354-361. (Pubitemid 29344850)
11. Green W, Patil P, Marsden CA, Bennett GW, and Wigmore PM (2006) Treatment with olanzapine increases cell proliferation in the subventricular zone and prefrontal cortex. Brain Res 1070:242-245. (Pubitemid 43247763)
12. Gutman DA, Owens MJ, Skelton KH, Thrivikraman KV, and Nemeroff CB (2003) The corticotropin-releasing factor1 receptor antagonist R121919 attenuates the behavioral and endocrine responses to stress. J Pharmacol Exp Ther 304:874-880. (Pubitemid 36152368)
13. Halim ND, Weickert CS, McClintock BW, Weinberger DR, and Lipska BK (2004) Effects of chronic haloperidol and clozapine treatment on neurogenesis in the adult rat hippocampus. Neuropsychopharmacology 29:1063-1069. (Pubitemid 38670044)
14. Holsboer F and Ising M (2008) Central CRH system in depression and anxiety- evidence from clinical studies with CRH1 receptor antagonists. Eur J Pharmacol 583:350-357.
15. Huang GJ and Herbert J (2006) Stimulation of neurogenesis in the hippocampus of the adult rat by fluoxetine requires rhythmic change in corticosterone. Biol Psychiatry 59:619-624.
16. Jaako-Movits K, Zharkovsky T, Pedersen M, and Zharkovsky A (2006) Decreased hippocampal neurogenesis following olfactory bulbectomy is reversed by repeated citalopram administration. Cell Mol Neurobiol 26:1559-1570. (Pubitemid 44924066)
17. Jayatissa MN, Bisgaard C, Tingström A, Papp M, and Wiborg O (2006) Hippocampal cytogenesis correlates to escitalopram-mediated recovery in a chronic mild stress rat model of depression. Neuropsychopharmacology 31:2395-2404. (Pubitemid 44607057)
18. Keilhoff G, Becker A, Grecksch G, Bernstein HG, and Wolf G (2006) Cell proliferation is influenced by bulbectomy and normalized by imipramine treatment in a region-specific manner. Neuropsychopharmacology 31:1165-1176. (Pubitemid 43971834)
19. Keitner GI, Garlow SJ, Ryan CE, Ninan PT, Solomon DA, Nemeroff CB, and Keller MB (2009) A randomized, placebo-controlled trial of risperidone augmentation for patients with difficult-to-treat unipolar, non-psychotic major depression. J Psychiatr Res 43:205-214.
20. Kodama M, Fujioka T, and Duman RS (2004) Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat. Biol Psychiatry 56:570-580. (Pubitemid 39336404)
21. Kwon YS, Jeong SW, Kim DW, Choi ES, and Son BK (2008) Effects of the ketogenic diet on neurogenesis after kainic acid-induced seizures in mice. Epilepsy Res 78:186-194.
22. Luo C, Xu H, and Li XM (2005) Quetiapine reverses the suppression of hippocampal neurogenesis caused by repeated restraint stress. Brain Res 1063:32-39. (Pubitemid 41628205)
23. Malberg JE, Eisch AJ, Nestler EJ, and Duman RS (2000) Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 20:9104-9110. (Pubitemid 32042912)
24. Mannens G, Huang ML, Meuldermans W, Hendrickx J, Woestenborghs R, and Heykants J (1993) Absorption, metabolism, and excretion of risperidone in humans. Drug Metab Dispos 21:1134-1141. (Pubitemid 23348354)
25. Marcussen AB, Flagstad P, Kristjansen PE, Johansen FF, and Englund U (2008) Increase in neurogenesis and behavioural benefit after chronic fluoxetine treatment in Wistar rats. Acta Neurol Scand 117:94-100.
26. Mirescu C, Peters JD, and Gould E (2004) Early life experience alters response of adult neurogenesis to stress. Nat Neurosci 7:841-846. (Pubitemid 38989507)
27. Mouton P (2002) Principles and Practices of Unbiased Stereology: An Introduction for Bioscientists. Johns Hopkins, Baltimore, MD.
28. Navailles S, Hof PR, and Schmauss C (2008) Antidepressant drug-induced stimulation of mouse hippocampal neurogenesis is age-dependent and altered by early life stress. J Comp Neurol 509:372-381.
29. Nazirizadeh Y, Vogel F, Bader W, Haen E, Pfuhlmann B, Gründer G, Paulzen M, Schwarz M, Zernig G, and Hiemke C (2010) Serum concentrations of paliperidone versus risperidone and clinical effects. Eur J Clin Pharmacol 66:797-803.
30. Nelson JC and Papakostas GI (2009) Atypical antipsychotic augmentation in major depressive disorder: a meta-analysis of placebo-controlled randomized trials. Am J Psychiatry 166:980-991.
31. Owens MJ, Morgan WN, Plott SJ, and Nemeroff CB (1997) Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther 283:1305-1322. (Pubitemid 28016506)
32. Rapaport MH, Gharabawi GM, Canuso CM, Mahmoud RA, Keller MB, Bossie CA, Turkoz I, Lasser RA, Loescher A, Bouhours P, et al. (2006) Effects of risperidone augmentation in patients with treatment-resistant depression: Results of open-label treatment followed by double-blind continuation. Neuropsychopharmacology 31:2505-2513. (Pubitemid 44607069)
33. Rivier CL, Grigoriadis DE, and Rivier JE (2003) Role of corticotropin-releasing factor receptors type 1 and 2 in modulating the rat adrenocorticotropin response to stressors. Endocrinology 144:2396-2403. (Pubitemid 36629890)
34. Rothschild AJ (2003) Challenges in the treatment of depression with psychotic features. Biol Psychiatry 53:680-690.
35. Schmidt HD and Duman RS (2007) The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive- like behavior. Behav Pharmacol 18:391-418. (Pubitemid 47356367)
36. Seager MA, Barth VN, Phebus LA, and Rasmussen K (2005) Chronic coadministration of olanzapine and fluoxetine activates locus coeruleus neurons in rats: implications for bipolar disorder. Psychopharmacology (Berl) 181:126-133.
37. Silva R, Mesquita AR, Bessa J, Sousa JC, Sotiropoulos I, Leão P, Almeida OF, and Sousa N (2008) Lithium blocks stress-induced changes in depressive-like behavior and hippocampal cell fate: the role of glycogen-synthase-kinase-3beta. Neuroscience 152:656-669.
38. Simon JS and Nemeroff CB (2005) Aripiprazole augmentation of antidepressants for the treatment of partially responding and nonresponding patients with major depressive disorder. J Clin Psychiatry 66:1216-1220. (Pubitemid 41546499)
39. Son H, Yu IT, Hwang SJ, Kim JS, Lee SH, Lee YS, Kaang BK, and Lee SH (2003) Lithium enhances long-term potentiation independently of hippocampal neurogenesis in the rat dentate gyrus. J Neurochem 85:872-881. (Pubitemid 36578619)
40. Surget A, Saxe M, Leman S, Ibarguen-Vargas Y, Chalon S, Griebel G, Hen R, and Belzung C (2008) Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal. Biol Psychiatry 64:293-301.
41. Wakade CG, Mahadik SP, Waller JL, and Chiu FC (2002) Atypical neuroleptics stimulate neurogenesis in adult rat brain. J Neurosci Res 69:72-79. (Pubitemid 34734166)
42. Xu H, Chen Z, He J, Haimanot S, Li X, Dyck L, and Li XM (2006) Synergetic effects of quetiapine and venlafaxine in preventing the chronic restraint stress-induced decrease in cell proliferation and BDNF expression in rat hippocampus. Hippocampus 16:551-559. (Pubitemid 43942103)