Neuropathologically defined subtypes of Alzheimer's disease differ significantly from neurofibrillary tangle-predominant dementia

Acta Neuropathologica

Volumn 124, Issue 5, 2012, Pages 681-692

  Janocko, Nicholas J ^a   Brodersen, Kevin A ^a   Soto Ortolaza, Alexandra I ^a   Ross, Owen A ^a   Liesinger, Amanda M ^a   Duara, Ranjan ^b   Graff Radford, Neill R ^c   Dickson, Dennis W ^a   Murray, Melissa E ^a  

^a MAYO GRADUATE SCHOOL   (United States)

^b MOUNT SINAI MEDICAL CENTER   (United States)

^c MAYO CLINIC   (United States)

Author keywords

Alzheimer disease; Amyloid plaques; APOE; Basal ganglia; Digital microscopy; MAPT; Neurofibrillary tangle predominant dementia; Neurofibrillary tangles

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; APOLIPOPROTEIN E EPSILON 4; DIRECT YELLOW 7; TAU PROTEIN; THIOFLAVINE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; BASAL GANGLION; CLASSIFICATION ALGORITHM; COGNITIVE DEFECT; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DEMENTIA; DIGITAL MICROSCOPY; DISEASE CLASSIFICATION; DISEASE DURATION; FASCIA DENTATA; FEMALE; FLUORESCENCE MICROSCOPY; GENE FREQUENCY; HIPPOCAMPAL SPARING ALZHEIMER DISEASE; HIPPOCAMPUS; HUMAN; IMMUNOREACTIVITY; LEWY BODY; LIMBIC PREDOMINANT ALZHEIMER DISEASE; LOCUS CERULEUS; MAJOR CLINICAL STUDY; MALE; MESENCEPHALON; MICROSCOPY; MIDDLE FRONTAL GYRUS; NEUROFIBRILLARY TANGLE; NEUROFIBRILLARY TANGLE PREDOMINANT DEMENTIA; NEUROPATHOLOGY; ONSET AGE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAPHE NUCLEUS; SENILE PLAQUE; SEX; STAGING; TYPICAL ALZHEIMER DISEASE;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; APOLIPOPROTEINS E; BRAIN; DEMENTIA; FEMALE; HUMANS; MALE; MIDDLE AGED; NEUROFIBRILLARY TANGLES; PEPTIDE FRAGMENTS; PLAQUE, AMYLOID; SEVERITY OF ILLNESS INDEX; TAU PROTEINS;

EID: 84870975209     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-012-1044-y     Document Type: Article

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