Very long chain ceramides interfere with C16-ceramide-induced channel formation: A plausible mechanism for regulating the initiation of intrinsic apoptosis

Biochimica et Biophysica Acta - Biomembranes

Volumn 1848, Issue 2, 2015, Pages 561-567

  Stiban, Johnny ^a   Perera, Meenu ^b,c  

^a BIRZEIT UNIVERSITY   (Palestine)

^b University of Maryland   (United States)

^c Intralytix Inc   (United States)

Author keywords

Ceramide channel; Cytochrome c release; Mitochondrial apoptosis; Sphingolipid; Very long chain fatty acid

Indexed keywords

CERAMIDE; CERAMIDE CHANNEL; CERAMIDE SYNTHASE; CYTOCHROME C; ION CHANNEL; SYNTHETASE; UNCLASSIFIED DRUG; VERY LONG CHAIN CERAMIDE; VERY LONG CHAIN FATTY ACID; ADENYLATE KINASE; CERS2 PROTEIN, HUMAN; CERS5 PROTEIN, HUMAN; DIHYDROCERAMIDE DESATURASE; LIPOSOME; MEMBRANE PROTEIN; OXIDOREDUCTASE; RECOMBINANT PROTEIN; SPHINGOSINE ACYLTRANSFERASE; TUMOR SUPPRESSOR PROTEIN;

APOPTOSIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INTERCALATION COMPLEX; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL PERMEABILITY; NONHUMAN; RAT; ANIMAL; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION; GENETICS; HEK293 CELL LINE; METABOLISM; MITOCHONDRION; PLASMID; SPRAGUE DAWLEY RAT; STRUCTURE ACTIVITY RELATION;

ADENYLATE KINASE; ANIMALS; APOPTOSIS; CELL SURVIVAL; CERAMIDES; GENE EXPRESSION; HEK293 CELLS; HUMANS; LIPOSOMES; MALE; MEMBRANE PROTEINS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; OXIDOREDUCTASES; PLASMIDS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SPHINGOSINE N-ACYLTRANSFERASE; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR SUPPRESSOR PROTEINS;

EID: 84914694906     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2014.11.018     Document Type: Article

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