Distinct roles for hematopoietic and extra-hematopoietic sphingosine kinase-1 in inflammatory bowel disease

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Snider, Ashley J ^a,b,c   Ali, Wahida H ^b   Sticca, Jonathan A ^d   Coant, Nicolas ^b   Ghaleb, Amr M ^b,c   Kawamori, Toshihiko ^e,f   Yang, Vincent W ^b,c   Hannun, Yusuf A ^b,c   Obeid, Lina M ^a,b,c  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c Stony Brook Medicine   (United States)

^d UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF HAWAII CANCER CENTER   (United States)

^f Ichinomiya Nishi Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; DEXTRAN SULFATE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE KINASE 1; STAT3 PROTEIN; LYSOPHOSPHOLIPID; PHOSPHOTRANSFERASE; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE 1-PHOSPHATE; SPHINGOSINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COMPONENT; COLITIS; COLON MUCOSA; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INDUCTION; ENZYME LOCALIZATION; EXTRAHEMATOPOIETIC COMPARTMENT; FEMALE; HEMATOPOIETIC COMPARTMENT; IMMUNE RESPONSE; INFLAMMATORY BOWEL DISEASE; LIPID BLOOD LEVEL; MALE; MOUSE; NEUTROPHILIA; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; GENETICS; HEMATOPOIETIC SYSTEM; INFLAMMATION; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ANIMALS; COLITIS; HEMATOPOIETIC SYSTEM; INFLAMMATION; INFLAMMATORY BOWEL DISEASES; LYSOPHOSPHOLIPIDS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RECEPTORS, LYSOSPHINGOLIPID; SPHINGOSINE;

EID: 84914669591     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0113998     Document Type: Article

References (39)

1. Mullen TD, Jenkins RW, Clarke CJ, Bielawski J, Hannun YA, et al. (2011) Ceramide synthasedependent ceramide generation and programmed cell death: involvement of salvage pathway in regulating postmitochondrial events. J Biol Chem 286: 15929-15942.
2. Teichgraber V, Ulrich M, Endlich N, Riethmuller J, Wilker B, et al. (2008) Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. Nat Med 14: 382-391.
3. Obeid LM, Linardic CM, Karolak LA, Hannun YA (1993) Programmed cell death induced by ceramide. Science 259: 1769-1771.
4. Heffernan-Stroud LA, Helke KL, Jenkins RW, De Costa AM, Hannun YA, et al. (2012) Defining a role for sphingosine kinase 1 in p53-dependent tumors. Oncogene 31: 1166-1175.
5. Venable ME, Lee JY, Smyth MJ, Bielawska A, Obeid LM (1995) Role of ceramide in cellular senescence. J Biol Chem 270: 30701-30708.
6. Pyne S, Pyne N (2000) Sphingosine 1-phosphate signalling via the endothelial differentiation gene family of G-protein-coupled receptors. Pharmacol Ther 88: 115-131.
7. Orr Gandy KA, Adada M, Canals D, Carroll B, Roddy P, et al. (2013) Epidermal growth factor-induced cellular invasion requires sphingosine-1-phosphate/sphingosine-1-phosphate 2 receptor-mediated ezrin activation. FASEB J.
8. Sarkar S, Maceyka M, Hait NC, Paugh SW, Sankala H, et al. (2005) Sphingosine kinase 1 is required for migration, proliferation and survival of MCF-7 human breast cancer cells. FEBS Lett 579: 5313-5317.
9. Chiba K (2005) FTY720, a new class of immunomodulator, inhibits lymphocyte egress from secondary lymphoid tissues and thymus by agonistic activity at sphingosine 1-phosphate receptors. Pharmacol Ther 108: 308-319.
10. Melendez AJ, Ibrahim FB (2004) Antisense knockdown of sphingosine kinase 1 in human macrophages inhibits C5a receptor-dependent signal transduction, Ca2+ signals, enzyme release, cytokine production, and chemotaxis. J Immunol 173: 1596-1603.
11. Ibrahim FB, Pang SJ, Melendez AJ (2004) Anaphylatoxin signaling in human neutrophils. A key role for sphingosine kinase. J Biol Chem 279: 44802-44811.
12. Jolly PS, Bektas M, Olivera A, Gonzalez-Espinosa C, Proia RL, et al. (2004) Transactivation of sphingosine-1-phosphate receptors by FcepsilonRI triggering is required for normal mast cell degranulation and chemotaxis. J Exp Med 199: 959-970.
13. Pushparaj PN, Manikandan J, Tay HK, H'Ng S C, Kumar SD, et al. (2009) Sphingosine kinase 1 is pivotal for Fc epsilon RI-mediated mast cell signaling and functional responses in vitro and in vivo. J Immunol 183: 221-227.
14. Pettus BJ, Bielawski J, Porcelli AM, Reames DL, Johnson KR, et al. (2003) The sphingosine kinase 1/sphingosine-1-phosphate pathway mediates COX-2 induction and PGE2 production in response to TNF-alpha. Faseb J 17: 1411-1421.
15. Billich A, Bornancin F, Mechtcheriakova D, Natt F, Huesken D, et al. (2005) Basal and induced sphingosine kinase 1 activity in A549 carcinoma cells: function in cell survival and IL-1beta and TNFalpha induced production of inflammatory mediators. Cell Signal 17: 1203-1217.
16. Snider AJ, Kawamori T, Bradshaw SG, Orr KA, Gilkeson GS, et al. (2009) A role for sphingosine kinase 1 in dextran sulfate sodium-induced colitis. Faseb J 23: 143-152.
17. Baker DA, Barth J, Chang R, Obeid LM, Gilkeson GS (2010) Genetic sphingosine kinase 1 deficiency significantly decreases synovial inflammation and joint erosions in murine TNF-alpha-induced arthritis. J Immunol 185: 2570-2579.
18. Liang J, Nagahashi M, Kim EY, Harikumar KB, Yamada A, et al. (2013) Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer. Cancer Cell 23: 107-120.
19. Baker DA, Eudaly J, Smith CD, Obeid LM, Gilkeson GS (2012) Impact of sphingosine kinase 2 deficiency on the development of TNF-alpha-induced inflammatory arthritis. Rheumatol Int.
20. Maines LW, Fitzpatrick LR, French KJ, Zhuang Y, Xia Z, et al. (2008) Suppression of ulcerative colitis in mice by orally available inhibitors of sphingosine kinase. Dig Dis Sci 53: 997-1012.
21. Bielawski J, Szulc ZM, Hannun YA, Bielawska A (2006) Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry. Methods 39: 82-91.
22. Muller PY, Janovjak H, Miserez AR, Dobbie Z (2002) Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechniques 32: 1372-1374, 1376, 1378-1379.
23. Chiba K, Matsuyuki H, Maeda Y, Sugahara K (2006) Role of sphingosine 1-phosphate receptor type 1 in lymphocyte egress from secondary lymphoid tissues and thymus. Cell Mol Immunol 3: 11-19.
24. Snider AJ, Wu BX, Jenkins RW, Sticca JA, Kawamori T, et al. (2012) Loss of neutral ceramidase increases inflammation in a mouse model of inflammatory bowel disease. Prostaglandins Other Lipid Mediat 99: 124-130.
25. Celikbilek M, Dogan S, Ozbakir O, Zararsiz G, Kucuk H, et al. (2013) Neutrophil-lymphocyte ratio as a predictor of disease severity in ulcerative colitis. J Clin Lab Anal 27: 72-76.
26. Torun S, Tunc BD, Suvak B, Yildiz H, Tas A, et al. (2012) Assessment of neutrophil-lymphocyte ratio in ulcerative colitis: a promising marker in predicting disease severity. Clin Res Hepatol Gastroenterol 36: 491-497.
27. Pappu R, Schwab SR, Cornelissen I, Pereira JP, Regard JB, et al. (2007) Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate. Science 316: 295-298.
28. Vogel P, Donoviel MS, Read R, Hansen GM, Hazlewood J, et al. (2009) Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and nonlymphoid lesions. PLoS One 4: e4112.
29. Allende ML, Sasaki T, Kawai H, Olivera A, Mi Y, et al. (2004) Mice deficient in sphingosine kinase 1 are rendered lymphopenic by FTY720. J Biol Chem 279: 52487-52492.
30. Michaud J, Kohno M, Proia RL, Hla T (2006) Normal acute and chronic inflammatory responses in sphingosine kinase 1 knockout mice. FEBS Lett 580: 4607-4612.
31. Zemann B, Urtz N, Reuschel R, Mechtcheriakova D, Bornancin F, et al. (2007) Normal neutrophil functions in sphingosine kinase type 1 and 2 knockout mice. Immunol Lett 109: 56-63.
32. Lee C, Xu DZ, Feketeova E, Kannan KB, Yun JK, et al. (2004) Attenuation of shock-induced acute lung injury by sphingosine kinase inhibition. J Trauma 57: 955-960.
33. Allende ML, Bektas M, Lee BG, Bonifacino E, Kang J, et al. (2011) Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking. J Biol Chem 286: 7348-7358.
34. Adada MM, Orr-Gandy KA, Snider AJ, Canals D, Hannun YA, et al. (2013) Sphingosine Kinase 1 (SK1) regulates Tumor Necrosis Factor (TNF)-mediated RANTES Induction Through p38 MAPK but Independently of NF-kappaB Activation. J Biol Chem.
35. Paugh BS, Bryan L, Paugh SW, Wilczynska KM, Alvarez SM, et al. (2009) Interleukin-1 regulates the expression of sphingosine kinase 1 in glioblastoma cells. J Biol Chem 284: 3408-3417.
36. Ross JS, Hu W, Rosen B, Snider AJ, Obeid LM, et al. (2013) Sphingosine Kinase 1 Is Regulated by Peroxisome Proliferator-activated Receptor alpha in Response to Free Fatty Acids and Is Essential for Skeletal Muscle Interleukin-6 Production and Signaling in Diet-induced Obesity. J Biol Chem 288: 22193-22206.
37. Rosillo MA, Sanchez-Hidalgo M, Cardeno A, Aparicio-Soto M, Sanchez-Fidalgo S, et al. (2012) Dietary supplementation of an ellagic acid-enriched pomegranate extract attenuates chronic colonic inflammation in rats. Pharmacol Res 66: 235-242.
38. Sanchez-Fidalgo S, Cardeno A, Villegas I, Talero E, de la Lastra CA (2010) Dietary supplementation of resveratrol attenuates chronic colonic inflammation in mice. Eur J Pharmacol 633: 78-84.
39. Kawamori T, Kaneshiro T, Okumura M, Maalouf S, Uflacker A, et al. (2009) Role for sphingosine kinase 1 in colon carcinogenesis. Faseb J 23: 405-414.