Human plasmacytoid dendritic cells regulate IFN-α production through activation-induced splicing of IL-18Rα

Journal of Leukocyte Biology

Volumn 96, Issue 6, 2014, Pages 1037-1046

  Chao, Yinxia ^a   Kaliaperumal, Nivashini ^a,b   Chretien, Anne Sophie ^a   Tang, Suisheng ^a   Lee, Bernett ^a   Poidinger, Michael ^a   Fairhurst, Anna Marie ^a,c   Connolly, John E ^a,b,d  

^a AGENCY FOR SCIENCE   (Singapore)

^b INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d BAYLOR UNIVERSITY   (United States)

Author keywords

Anti viral response; Inflammation; Innate immunity

Indexed keywords

ALPHA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 18 RECEPTOR ALPHA; INTERLEUKIN 18 RECEPTOR ALPHA 1; INTERLEUKIN 18 RECEPTOR ALPHA 2; UNCLASSIFIED DRUG; CXCL10 PROTEIN, HUMAN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 18; INTERLEUKIN 18 RECEPTOR; ISOPROTEIN;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INFLUENZA; INTRACELLULAR SIGNALING; NATURAL KILLER CELL; PLASMACYTOID DENDRITIC CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; ANTAGONISTS AND INHIBITORS; BINDING COMPETITION; BIOSYNTHESIS; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; DENDRITIC CELL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; INFLUENZA VIRUS A H1N1; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN TERTIARY STRUCTURE; RNA SPLICING; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

BASE SEQUENCE; BINDING, COMPETITIVE; CELL DIFFERENTIATION; CELLS, CULTURED; CHEMOKINE CXCL10; DENDRITIC CELLS; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INTERFERON-ALPHA; INTERFERON-GAMMA; INTERLEUKIN-12; INTERLEUKIN-18; KILLER CELLS, NATURAL; MOLECULAR SEQUENCE DATA; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, INTERLEUKIN-18; RNA SPLICING; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID; SIGNAL TRANSDUCTION;

EID: 84914179783     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.2A0813-465RR     Document Type: Article

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