The interplay of chemokines and dendritic cells in the pathogenesis of lupus nephritis

Annals of the New York Academy of Sciences

Volumn 1051, Issue , 2005, Pages 421-432

  Tucci, Marco ^a   Calvani, Nicola ^a   Richards, Hanno B ^b   Quatraro, Cosima ^a   Silvestris, Franco ^a  

^a UNIVERSITY OF BARI   (Italy)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Dendritic cells; Interleukin 18; Lupus nephritis; SLE

Indexed keywords

AUTOANTIBODY; CHEMOKINE; CHEMOKINE RECEPTOR; INTERLEUKIN 18; INTERLEUKIN 18 RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1;

BONE MARROW CELL; CONFERENCE PAPER; CYTOKINE PRODUCTION; DENDRITIC CELL; GLOMERULONEPHRITIS; GLOMERULUS; HEMOSTASIS; HUMAN; IMMUNE COMPLEX DEPOSITION; INFLAMMATION; KIDNEY DISEASE; LUPUS ERYTHEMATOSUS NEPHRITIS; MACROPHAGE; NONHUMAN; PATHOGENESIS; PLASMA CELL; SYSTEMIC LUPUS ERYTHEMATOSUS;

EID: 25444504487     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1361.084     Document Type: Conference Paper

References (40)

1. KELLEY, V.R. & R.P. WUTHRICH. 1999. Cytokines in the pathogenesis of systemic lupus erythematosus. Semin. Nephrol. 19: 57-66.
2. HANDWERGER, B.S., V. RUS, L. DA SILVA & C.S. VIA. 1994. The role of cytokines in the immunopathogenesis of lupus. Springer Semin. Immunopathol. 16: 153-180.
3. PEREZ DE LEMA, G., H. MAIER, E. NIETO, et al. 2001. Chemokine expression precedes inflammatory cell infiltration and chemokine receptor and cytokine expression during the initiation of murine lupus nephritis. J. Am. Soc. Nephrol. 12: 1369-1382.
4. WADA, T., K. FURUICHI, C. SEGAWA-TAKAEDA, et al. 1999. MIP-1alpha and MCP-1 contribute to crescents and interstitial lesions in human crescentic glomerulonephritis. Kidney Int. 56: 995-1003.
5. TESCH, G.H., S. MAIFERT, A. SCHWARTING, et al. 1999. Monocyte chemoattractant protein 1-dependent leukocytic infiltrates are responsible for autoimmune disease in MRL-Fas(1pr) mice. J. Exp. Med. 190: 1813-1824.
6. WADA, T., H. YOKOYAMA, S.B. SU, et al. 1996. Monitoring urinary levels of monocyte chemotactic and activating factor reflects disease activity of lupus nephritis. Kidney Int. 49: 761-767.
7. KLUTH, D.C., L.P. ERWIG & A.J. REES. 2004. Multiple facets of macrophages in renal injury. Kidney Int. 66: 542-557.
8. BALABANIAN, K., J. COUDERC, L. BOUCHET-DELBOS, et al. 2003. Role of the chemokine stromal cell-derived factor 1 in autoantibody production and nephritis in murine lupus. J. Immunol. 170: 3392-3400.
9. SCHEINECKER, C., B. ZWOLFER, M. KOLLER, et al. 2001. Alterations of dendritic cells in systemic: lupus erythematosus: phenotypic and functional deficiencies. Arthritis Rheum. 44: 856-865.
10. PENNA, G., M. VULCANO, S. SOZZANI & L. ADORINI. 2002. Differential migration behavior and chemokine production by myeloid and plasmacytoid dendritic cells. Hum. Immunol. 63: 1164-1171.
11. PENNA, G., S. SOZZANI & L. ADORINI. 2001. Cutting edge: selective usage of chemokine receptors by plasmacytoid dendritic cells. J. Immunol. 167: 1862-1866.
12. KASER, A., S. KASER, N.C. KANEIDER, et al. 2004. Interleukin-18 attracts plasmacytoid dendritic cells (DC2s) and promotes Th1 induction by DC2s through IL-18 receptor expression. Blood 103: 648-655.
13. LLOYD, C.M., A.W. MINTO, M.E. DORF, et al. 1997. RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis. J. Exp. Med. 185: 1371-1380.
14. YOSHIMURA, T., E.A. ROBINSON, S. TANAKA, et al. 1989. Purification and amino acid analysis of two human monocyte chemoattractants produced by phytohemagglutinin-stimulated human blood mononuclear leukocytes. J. Immunol. 142: 1956-1962.
15. HORA, K., J.A. SATRIANO, A. SANTIAGO, et al. 1992. Receptors for IgG complexes activate synthesis of monocyte chemoattractant peptide 1 and colony-stimulating factor 1. Proc. Natl. Acad. Sci. USA 89: 1745-1749.
16. NORIS, M., S. BERNASCONI, F. CASIRAGHI, et al. 1995. Monocyte chemoattractant protein-1 is excreted in excessive amounts in the urine of patients with lupus nephritis. Lab. Invest. 73: 804-809.
17. BISWAS, P., F. DELFANTI, S. BERNASCONI, et al. 1998. Interleukin-6 induces monocyte chemotactic protein-1 in peripheral blood mononuclear cells and in the U937 cell line. Blood 91: 258-265.
18. LU, B., B.J. RUTLEDGE & L. GU, et al. 1998. Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice. J. Exp. Med. 187: 601-608.
19. TANG, W.W., M. QI & J.S. WARREN. 1996. Monocyte chemoattractant protein 1 mediates glomerular macrophage infiltration in anti-GBM Ab GN. Kidney Int. 50: 665-671.
20. HASEGAWA, H., M. KOHNO, M. SASAKI, et al. 2003. Antagonist of monocyte chemoattractant protein 1 ameliorates the initiation and progression of lupus nephritis and renal vasculitis in MRL/1pr mice. Arthritis Rheum. 48: 2555-2566.
21. TESCH, G.H., A. SCHWARTING, K. KINOSHITA, et al. 1999. Monocyte chemoattractant protein-1 promotes macrophage-mediated tubular injury, but not glomerular injury, in nephrotoxic serum nephritis. J. Clin. Invest. 103: 73-80.
22. TUCCI, M., E.V. BARNES, E.S. SOBEL, et al. 2004. Strong association of a functional polymorphism in the monocyte chemoattractant protein 1 promoter gene with lupus nephritis. Arthritis Rheum 50: 1842-1849.
23. DAUGHERTY, B.L. & M.S. SPRINGER. 1997. The beta-chemokine receptor genes CCR1 (CMKBR1), CCR2 (CMKBR2), and CCR3 (CMKBR3) cluster within 285 kb on human chromosome 3p21. Genomics 41: 294-295.
24. WONG, L.M., S.J. MYERS, C.L. TSOU, et al. 1997. Organization and differential expression of the human monocyte chemoattractant protein 1 receptor gene: evidence for the role of the carboxyl-terminal tail in receptor trafficking. J. Biol. Chem. 272: 1038-1045.
25. PETERS, W., M. DUPUIS & I.F. CHARO. 2000. A mechanism for the impaired IFN-gamma production in C-C chemokine receptor 2 (CCR2) knockout mice: role of CCR2 in linking the innate and adaptive immune responses. J. Immunol. 165: 7072-7077.
26. PETERS, W., H.M. SCOTT, H.F. CHAMBERS, et al. 2001. Chemokine receptor 2 serves an early and essential role in resistance to Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. USA 98: 7958-7963.
27. BORING, L., J. GOSLING, M. CLEARY & L.F. CHARO. 1998. Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature 394: 894-897.
28. SMITH, M.W., M. DEAN, M. CARRINGTON, et al. 1997. Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC), ALIVE Study. Science 277: 959-965.
29. SEGERER S., K.M. MAC, H. REGELE H., et al. 1999. Expression of the C-C chemokine receptor 5 in human kidney diseases. Kidney Int. 56: 52-64.
30. NATORI, Y., M. SEKIGUCHI & Z. OU. 1997. Gene expression of CC chemokines in experimental crescentic glomerulonephritis (CGN). Clin. Exp. Immunol. 109: 143-148.
31. BLOMBERG, S., M.L. ELORANTA, M. MAGNUSSON, et al. 2003. Expression of the markers BDCA-2 and BDCA-4 and production of interferon-alpha by plasmacytoid dendritic cells in systemic lupus erythematosus. Arthritis Rheum. 48: 2524-2532.
32. PENNA, G., M. VULCANO, A. RONCARI, et al. 2002. Cutting edge: differential chemokine production by myeloid and plasmacytoid dendritic cells. J. Immunol. 169: 6673-6676.
33. FARKAS, L., K. BEISKE, F. LUND-JOHANSEN, et al. 2001. Plasmacytoid dendritic cells (natural interferon- alpha/beta-producing cells) accumulate in cutaneous lupus erythematosus lesions. Am. J. Pathol. 159: 237-243.
34. PAGE, G., G. CHEVREL & P. MIOSSEC. 2004. Anatomic localization of immature and mature dendritic cell subsets in dermatomyositis and polymyositis: interaction with chemokines and Th1 cytokine-producing cells. Arthritis Rheum. 50: 199-208.
35. CALVANI N., SATOH M., CROKER B. P., et al. 2003. Nephritogenic autoantibodies but absence of nephritis in Il-12p35-deficient mice with pristane-induced lupus. Kidney Int. 64: 897-905.
36. RICHARDS, H.B., M. SATOH, J.C. JENNETTE, et al. 2001. Interferon-gamma is required for lupus nephritis in mice treated with the hydrocarbon oil pristane. Kidney Int. 60: 2173-2180.
37. AKAHOSHI, M., H. NAKASHIMA, Y. TANAKA Y, et al. 1999. Th1/Th2 balance of peripheral T helper cells in systemic lupus erythematosus. Arthritis Rheum. 42: 1644-1648.
38. CALVANI, N., H.B. RICHARDS, M. TUCCI, et al. 2004. Up-regulation of IL-18 and predominance of a Th1 immune response is a hallmark of lupus nephritis. Clin. Exp. Immunol. 138: 1711-1718.
39. DE JONG, B.C., P.L. VIEIRA, P. KALINSKI, et al. 2002. Microbial compounds selectively induce Th1 cell-promoting or Th2 cell-promoting dendritic cells in vitro with diverse th cell-polarizing signals. J. Immunol. 168: 1704-1709.
40. DZIONEK, A., Y. SOHMA, J. NAGAFUNE, et al. 2001. BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen capture and is a potent inhibitor of interferon alpha/beta induction. J. Exp. Med. 194: 1823-1834.