Global epigenomic analysis indicates protocadherin-7 activates osteoclastogenesis by promoting cell-cell fusion

Biochemical and Biophysical Research Communications

Volumn 455, Issue 3-4, 2014, Pages 305-311

  Nakamura, Haruhiko ^a,b   Nakashima, Tomoki ^b,c   Hayashi, Mikihito ^b,c   Izawa, Naohiro ^a   Yasui, Tetsuro ^a   Aburatani, Hiroyuki ^d   Tanaka, Sakae ^a   Takayanagi, Hiroshi ^a,c  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

Cell cell fusion; Epigenetics; Osteoclast; Protocadherin 7 (Pcdh7); RANKL

Indexed keywords

CYCLOSPORIN A; GLYCOPROTEIN; HISTONE H3; HISTONE H3 LYSINE 27; HISTONE H3 LYSINE 4; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; OSTEOCLAST DIFFERENTIATION FACTOR; PROTOCADHERIN 7; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; ATP6V0D2 PROTEIN, HUMAN; CADHERIN; DCSTAMP PROTEIN, HUMAN; HISTONE; MEMBRANE PROTEIN; OC-STAMP PROTEIN, HUMAN; PCDH7 PROTEIN, HUMAN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ARTICLE; BONE METABOLISM; CELL ADHESION; CELL FUSION; CELL POPULATION; CHROMATIN IMMUNOPRECIPITATION; EPIGENETICS; FLUORESCENCE MICROSCOPY; GENE SEQUENCE; HISTONE MODIFICATION; IN VITRO STUDY; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PROTEIN EXPRESSION; REGULATOR GENE; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION SITE; CELL COMMUNICATION; CYTOLOGY; FLOW CYTOMETRY; GENETIC EPIGENESIS; HUMAN; MACROPHAGE; METABOLISM; MONOCYTE; SEQUENCE ANALYSIS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BONE RESORPTION; CADHERINS; CELL COMMUNICATION; CHROMATIN IMMUNOPRECIPITATION; EPIGENESIS, GENETIC; EPIGENOMICS; FLOW CYTOMETRY; HISTONES; HUMANS; MACROPHAGES; MEMBRANE PROTEINS; MONOCYTES; OSTEOCLASTS; RANK LIGAND; SEQUENCE ANALYSIS, RNA; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 84914154744     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.11.009     Document Type: Article

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