A mutation in the mitochondrial protein UQCRB promotes angiogenesis through the generation of mitochondrial reactive oxygen species

Biochemical and Biophysical Research Communications

Volumn 455, Issue 3-4, 2014, Pages 290-297

  Chang, Junghwa ^a   Jung, Hye Jin ^b   Jeong, Seung Hun ^d   Kim, Hyoung Kyu ^d   Han, Jin ^d   Kwon, Ho Jeong ^a,c  

^a Yonsei University   (South Korea)

^b SunMoon University   (South Korea)

^c Yonsei University College of Medicine   (South Korea)

^d Inje University College of Medicine   (South Korea)

Author keywords

Angiogenesis; Complex III; Mitochondria; Mitochondrial reactive oxygen species; UQCRB

Indexed keywords

BINDING PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MUTANT PROTEIN; OXIDOREDUCTASE INHIBITOR; REACTIVE OXYGEN METABOLITE; UBIQUINOL CYTOCHROME C REDUCTASE; UBIQUINOL CYTOCHROME C REDUCTASE BINDING PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN; ADENOSINE TRIPHOSPHATE; BICYCLO COMPOUND; CARRIER PROTEIN; LACTIC ACID; MITOCHONDRIAL PROTEIN; TERPESTACIN; UBIQUINONE-BINDING PROTEINS; VASCULOTROPIN A;

ANGIOGENESIS; ANGIOGENESIS ASSAY; ARTICLE; CELL GROWTH; CELL PROLIFERATION; COLONY FORMATION; COLORIMETRY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE CONSTRUCT; GENE MUTATION; GENETIC TRANSFECTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRION; MTT ASSAY; OXYGEN SENSING; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SWELLING; WESTERN BLOTTING; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MUTATION; NEOVASCULARIZATION (PATHOLOGY); NUCLEOTIDE SEQUENCE; OXYGEN CONSUMPTION; SEQUENCE HOMOLOGY; TRANSMISSION ELECTRON MICROSCOPY; UMBILICAL VEIN ENDOTHELIAL CELL;

ADENOSINE TRIPHOSPHATE; BASE SEQUENCE; BICYCLO COMPOUNDS; CARRIER PROTEINS; CELL PROLIFERATION; CLONING, MOLECULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEK293 CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LACTIC ACID; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; NEOVASCULARIZATION, PATHOLOGIC; OXYGEN CONSUMPTION; REACTIVE OXYGEN SPECIES; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84914142971     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.11.005     Document Type: Article

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