-
1
-
-
84861235692
-
Molecular pathways regulating macrophage polarization: Implications for atherosclerosis
-
Hoeksema MA, Stoger JL, de Winther MP. Molecular pathways regulating macrophage polarization: Implications for atherosclerosis. Curr Atheroscler Rep 2012; 14: 254-263.
-
(2012)
Curr Atheroscler Rep
, vol.14
, pp. 254-263
-
-
Hoeksema, M.A.1
Stoger, J.L.2
De Winther, M.P.3
-
2
-
-
84892921988
-
Reprogramming macrophages to an anti-inflammatory phenotype by helminth antigens reduces murine atherosclerosis
-
Wolfs IM, Stoger JL, Goossens P, et al. Reprogramming macrophages to an anti-inflammatory phenotype by helminth antigens reduces murine atherosclerosis. FASEB J 2014; 28: 288-299.
-
(2014)
FASEB J
, vol.28
, pp. 288-299
-
-
Wolfs, I.M.1
Stoger, J.L.2
Goossens, P.3
-
3
-
-
84879103109
-
Macrophage activation and polarization as an adaptive component of innate immunity
-
Locati M, Mantovani A, Sica A. Macrophage activation and polarization as an adaptive component of innate immunity. Adv Immunol 2013; 120: 163-184.
-
(2013)
Adv Immunol
, vol.120
, pp. 163-184
-
-
Locati, M.1
Mantovani, A.2
Sica, A.3
-
4
-
-
73949140039
-
Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes
-
Van den Bossche J, Bogaert P, van Hengel J, et al. Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes. Blood 2009; 114: 4664-4674.
-
(2009)
Blood
, vol.114
, pp. 4664-4674
-
-
Van Den Bossche, J.1
Bogaert, P.2
Van Hengel, J.3
-
5
-
-
84860896083
-
Pivotal advance: Arginase-1- independent polyamine production stimulates the expression of IL-4-induced alternatively activated macrophage markers while inhibiting LPS-induced expression of inflammatory genes
-
Van den Bossche J, LamersWH,Koehler ES, et al. Pivotal advance: Arginase-1- independent polyamine production stimulates the expression of IL-4-induced alternatively activated macrophage markers while inhibiting LPS-induced expression of inflammatory genes. J Leukoc Biol 2012; 91: 685-699.
-
(2012)
J Leukoc Biol
, vol.91
, pp. 685-699
-
-
Van Den Bossche, J.1
Lamers, W.H.2
Koehler, E.S.3
-
6
-
-
84875658660
-
Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: Similarities and differences
-
Martinez FO, Helming L, Milde R, et al. Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: Similarities and differences. Blood 2013; 121: E57-e69.
-
(2013)
Blood
, vol.121
, pp. e57-e69
-
-
Martinez, F.O.1
Helming, L.2
Milde, R.3
-
7
-
-
84885956378
-
Epigenomic control of the innate immune response
-
Stender JD, Glass CK. Epigenomic control of the innate immune response. Curr Opin Pharmacol 2013; 13: 582-587.
-
(2013)
Curr Opin Pharmacol
, vol.13
, pp. 582-587
-
-
Stender, J.D.1
Glass, C.K.2
-
8
-
-
84891439321
-
Deciphering cis-regulatory control in inflammatory cells
-
Ghisletti S, Natoli G. Deciphering cis-regulatory control in inflammatory cells. Philos Trans R Soc Lond B Biol Sci 2013; 368: 20120370.
-
(2013)
Philos Trans R Soc Lond B Biol Sci
, vol.368
, pp. 20120370
-
-
Ghisletti, S.1
Natoli, G.2
-
9
-
-
77949977555
-
Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages
-
Ghisletti S, Barozzi I, Mietton F, et al. Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. Immunity 2010; 32: 317-328.
-
(2010)
Immunity
, vol.32
, pp. 317-328
-
-
Ghisletti, S.1
Barozzi, I.2
Mietton, F.3
-
10
-
-
84859973805
-
Specialized chromatin patterns in the control of inflammatory gene expression
-
Natoli G. Specialized chromatin patterns in the control of inflammatory gene expression. Curr Top Microbiol Immunol 2011; 349: 61-72.
-
(2011)
Curr Top Microbiol Immunol
, vol.349
, pp. 61-72
-
-
Natoli, G.1
-
11
-
-
77952567987
-
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
-
Heinz S, Benner C, Spann N, et al. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell 2010; 38: 576-589.
-
(2010)
Mol Cell
, vol.38
, pp. 576-589
-
-
Heinz, S.1
Benner, C.2
Spann, N.3
-
12
-
-
84888641656
-
Effect of natural genetic variation on enhancer selection and function
-
Heinz S, Romanoski CE, Benner C, et al. Effect of natural genetic variation on enhancer selection and function. Nature 2013; 503: 487-492.
-
(2013)
Nature
, vol.503
, pp. 487-492
-
-
Heinz, S.1
Romanoski, C.E.2
Benner, C.3
-
13
-
-
84881526410
-
Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription
-
Kaikkonen MU, Spann NJ, Heinz S, et al. Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription. Mol Cell 2013; 51: 310-325.
-
(2013)
Mol Cell
, vol.51
, pp. 310-325
-
-
Kaikkonen, M.U.1
Spann, N.J.2
Heinz, S.3
-
14
-
-
84872522528
-
Latent enhancers activated by stimulation in differentiated cells
-
Ostuni R, Piccolo V, Barozzi I, et al. Latent enhancers activated by stimulation in differentiated cells. Cell 2013; 152: 157-171.
-
(2013)
Cell
, vol.152
, pp. 157-171
-
-
Ostuni, R.1
Piccolo, V.2
Barozzi, I.3
-
15
-
-
84888151312
-
Functional genomics of the inflammatory response: Where are we now?
-
Simonatto M, Natoli G. Functional genomics of the inflammatory response: Where are we now? Brief Funct Genomics 2013; 12: 483-488.
-
(2013)
Brief Funct Genomics
, vol.12
, pp. 483-488
-
-
Simonatto, M.1
Natoli, G.2
-
16
-
-
33847334699
-
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
-
Heintzman ND, Stuart RK, Hon G, et al. Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat Genet 2007; 39: 311-318.
-
(2007)
Nat Genet
, vol.39
, pp. 311-318
-
-
Heintzman, N.D.1
Stuart, R.K.2
Hon, G.3
-
17
-
-
65549104157
-
Histone modifications at human enhancers reflect global cell-type-specific gene expression
-
Heintzman ND, Hon GC, Hawkins RD, et al. Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature 2009; 459: 108-112.
-
(2009)
Nature
, vol.459
, pp. 108-112
-
-
Heintzman, N.D.1
Hon, G.C.2
Hawkins, R.D.3
-
18
-
-
78650758676
-
Histone H3K27ac separates active from poised enhancers and predicts developmental state
-
Creyghton MP, Cheng AW, Welstead GG, et al. Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proc Natl Acad Sci U S A 2010; 107: 21931-21936.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 21931-21936
-
-
Creyghton, M.P.1
Cheng, A.W.2
Welstead, G.G.3
-
19
-
-
79951516056
-
A unique chromatin signature uncovers early developmental enhancers in humans
-
Rada-Iglesias A, Bajpai R, Swigut T, et al. A unique chromatin signature uncovers early developmental enhancers in humans. Nature 2011; 470: 279-283.
-
(2011)
Nature
, vol.470
, pp. 279-283
-
-
Rada-Iglesias, A.1
Bajpai, R.2
Swigut, T.3
-
20
-
-
46249112085
-
Combinatorial patterns of histone acetylations and methylations in the human genome
-
Wang Z, Zang C, Rosenfeld JA, et al. Combinatorial patterns of histone acetylations and methylations in the human genome. Nat Genet 2008; 40: 897-903.
-
(2008)
Nat Genet
, vol.40
, pp. 897-903
-
-
Wang, Z.1
Zang, C.2
Rosenfeld, J.A.3
-
21
-
-
84886897279
-
Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage phenotypes
-
Kittan NA, Allen RM, Dhaliwal A, et al. Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage phenotypes. PLoS One 2013; 8: E78045.
-
(2013)
PLoS One
, vol.8
, pp. e78045
-
-
Kittan, N.A.1
Allen, R.M.2
Dhaliwal, A.3
-
22
-
-
84867397456
-
Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20
-
Stender JD, Pascual G, Liu W, et al. Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20. Mol Cell 2012; 48: 28-38.
-
(2012)
Mol Cell
, vol.48
, pp. 28-38
-
-
Stender, J.D.1
Pascual, G.2
Liu, W.3
-
23
-
-
34548644772
-
The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing
-
De Santa F, Totaro MG, Prosperini E, et al. The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing. Cell 2007; 130: 1083-1094.
-
(2007)
Cell
, vol.130
, pp. 1083-1094
-
-
De Santa, F.1
Totaro, M.G.2
Prosperini, E.3
-
24
-
-
70350754328
-
Jmjd3 contributes to the control of gene expression in LPS-activated macrophages
-
De Santa F, Narang V, Yap ZH, et al. Jmjd3 contributes to the control of gene expression in LPS-activated macrophages. EMBO J 2009; 28: 3341-3352.
-
(2009)
EMBO J
, vol.28
, pp. 3341-3352
-
-
De Santa, F.1
Narang, V.2
Yap, Z.H.3
-
25
-
-
84901775237
-
Jmjd3-mediated epigenetic regulation of inflammatory cytokine gene expression in serum amyloid A-stimulated macrophages
-
Yan Q, Sun L, Zhu Z, et al. Jmjd3-mediated epigenetic regulation of inflammatory cytokine gene expression in serum amyloid A-stimulated macrophages. Cell Signal 2014; 26: 1783-1791.
-
(2014)
Cell Signal
, vol.26
, pp. 1783-1791
-
-
Yan, Q.1
Sun, L.2
Zhu, Z.3
-
26
-
-
84865120905
-
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
-
Kruidenier L, Chung CW, Cheng Z, et al. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature 2012; 488: 404-408.
-
(2012)
Nature
, vol.488
, pp. 404-408
-
-
Kruidenier, L.1
Chung, C.W.2
Cheng, Z.3
-
27
-
-
70350435962
-
Epigenetic regulation of the alternatively activated macrophage phenotype
-
Ishii M, Wen H, Corsa CA, et al. Epigenetic regulation of the alternatively activated macrophage phenotype. Blood 2009; 114: 3244-3254.
-
(2009)
Blood
, vol.114
, pp. 3244-3254
-
-
Ishii, M.1
Wen, H.2
Corsa, C.A.3
-
28
-
-
77956954197
-
The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
-
Satoh T, Takeuchi O, Vandenbon A, et al. The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection. Nat Immunol 2010; 11: 936-944.
-
(2010)
Nat Immunol
, vol.11
, pp. 936-944
-
-
Satoh, T.1
Takeuchi, O.2
Vandenbon, A.3
-
29
-
-
80055018787
-
Epigenetic regulation of osteoclast differentiation: Possible involvement of Jmjd3 in the histone demethylation of Nfatc1
-
Yasui T, Hirose J, Tsutsumi S, et al. Epigenetic regulation of osteoclast differentiation: Possible involvement of Jmjd3 in the histone demethylation of Nfatc1. J Bone Miner Res 2011; 26: 2665-2671.
-
(2011)
J Bone Miner Res
, vol.26
, pp. 2665-2671
-
-
Yasui, T.1
Hirose, J.2
Tsutsumi, S.3
-
30
-
-
84862622207
-
The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation
-
Chen S, Ma J, Wu F, et al. The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation. Genes Dev 2012; 26: 1364-1375.
-
(2012)
Genes Dev
, vol.26
, pp. 1364-1375
-
-
Chen, S.1
Ma, J.2
Wu, F.3
-
31
-
-
82955247088
-
Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation
-
Mullican SE, Gaddis CA, Alenghat T, et al. Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation. Genes Dev 2011; 25: 2480-2488.
-
(2011)
Genes Dev
, vol.25
, pp. 2480-2488
-
-
Mullican, S.E.1
Gaddis, C.A.2
Alenghat, T.3
-
32
-
-
84867652835
-
Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages
-
Chen X, Barozzi I, Termanini A, et al. Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages. Proc Natl Acad Sci U S A 2012; 109: E2865-E2874.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. E2865-E2874
-
-
Chen, X.1
Barozzi, I.2
Termanini, A.3
-
33
-
-
79251554670
-
Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection
-
Roger T, Lugrin J, Le RD, et al. Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection. Blood 2011; 117: 1205-1217.
-
(2011)
Blood
, vol.117
, pp. 1205-1217
-
-
Roger, T.1
Lugrin J Le, R.D.2
-
34
-
-
84891050049
-
The response of secondary genes to lipopolysaccharides in macrophages depends on histone deacetylase and phosphorylation of CCAAT(cytosine-cytosine-adenosine-adenosinethymidine)/ enhancer binding protein beta
-
Serrat N, Sebastian C, Pereira-Lopes S, et al. The response of secondary genes to lipopolysaccharides in macrophages depends on histone deacetylase and phosphorylation of CCAAT(cytosine-cytosine-adenosine-adenosinethymidine)/ enhancer binding protein beta. J Immunol 2014; 192: 418-426.
-
(2014)
J Immunol
, vol.192
, pp. 418-426
-
-
Serrat, N.1
Sebastian, C.2
Pereira-Lopes, S.3
-
35
-
-
79959804516
-
Histone deacetylases as regulators of inflammation and immunity
-
ShakespearMR, Halili MA, Irvine KM, et al. Histone deacetylases as regulators of inflammation and immunity. Trends Immunol 2011; 32: 335-343.
-
(2011)
Trends Immunol
, vol.32
, pp. 335-343
-
-
Shakespear, M.R.1
Halili, M.A.2
Irvine, K.M.3
-
36
-
-
84899856633
-
Histone deacetylase isoforms regulate innate immune responses by deacetylating mitogen-activated protein kinase phosphatase- 1
-
Jeong Y, Du R, Zhu X, et al. Histone deacetylase isoforms regulate innate immune responses by deacetylating mitogen-activated protein kinase phosphatase- 1. J Leukoc Biol 2014; 95: 651-659.
-
(2014)
J Leukoc Biol
, vol.95
, pp. 651-659
-
-
Jeong, Y.1
Du, R.2
Zhu, X.3
-
37
-
-
84880616633
-
The class III histone deacetylase sirtuin 1 in immune suppression and its therapeutic potential in rheumatoid arthritis
-
Kong S, Yeung P, Fang D. The class III histone deacetylase sirtuin 1 in immune suppression and its therapeutic potential in rheumatoid arthritis. J Genet Genomics 2013; 40: 347-354.
-
(2013)
J Genet Genomics
, vol.40
, pp. 347-354
-
-
Kong, S.1
Yeung, P.2
Fang, D.3
-
38
-
-
79951881254
-
Protective roles of SIRT1 in atherosclerosis
-
Stein S, Matter CM. Protective roles of SIRT1 in atherosclerosis. Cell Cycle 2011; 10: 640-647.
-
(2011)
Cell Cycle
, vol.10
, pp. 640-647
-
-
Stein, S.1
Matter, C.M.2
-
39
-
-
84873256270
-
BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses
-
Belkina AC, Nikolajczyk BS, Denis GV. BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses. J Immunol 2013; 190: 3670-3678.
-
(2013)
J Immunol
, vol.190
, pp. 3670-3678
-
-
Belkina, A.C.1
Nikolajczyk, B.S.2
Denis, G.V.3
-
40
-
-
78650806593
-
Suppression of inflammation by a synthetic histone mimic
-
Nicodeme E, Jeffrey KL, Schaefer U, et al. Suppression of inflammation by a synthetic histone mimic. Nature 2010; 468: 1119-1123.
-
(2010)
Nature
, vol.468
, pp. 1119-1123
-
-
Nicodeme, E.1
Jeffrey, K.L.2
Schaefer, U.3
-
41
-
-
84885573359
-
Circadian gene Bmal1 regulates diurnal oscillations of Ly6C(hi) inflammatory monocytes
-
Nguyen KD, Fentress SJ, Qiu Y, et al. Circadian gene Bmal1 regulates diurnal oscillations of Ly6C(hi) inflammatory monocytes. Science 2013; 341: 1483-1488.
-
(2013)
Science
, vol.341
, pp. 1483-1488
-
-
Nguyen, K.D.1
Fentress, S.J.2
Qiu, Y.3
-
42
-
-
84887549060
-
The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells
-
Tumes DJ, Onodera A, Suzuki A, et al. The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells. Immunity 2013; 39: 819-832.
-
(2013)
Immunity
, vol.39
, pp. 819-832
-
-
Tumes, D.J.1
Onodera, A.2
Suzuki, A.3
-
43
-
-
82955247088
-
Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation
-
Mullican SE, Gaddis CA, Alenghat T, et al. Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation. Genes Dev 2011; 25: 2480-2488.
-
(2011)
Genes Dev
, vol.25
, pp. 2480-2488
-
-
Mullican, S.E.1
Gaddis, C.A.2
Alenghat, T.3
-
44
-
-
84875755814
-
Influence of metabolism on epigenetics and disease
-
Kaelin WG Jr, McKnight SL. Influence of metabolism on epigenetics and disease. Cell 2013; 153: 56-69.
-
(2013)
Cell
, vol.153
, pp. 56-69
-
-
Kaelin, W.G.1
McKnight, S.L.2
-
45
-
-
84876758617
-
Metabolic pathways in immune cell activation and quiescence
-
Pearce EL, Pearce EJ. Metabolic pathways in immune cell activation and quiescence. Immunity 2013; 38: 633-643.
-
(2013)
Immunity
, vol.38
, pp. 633-643
-
-
Pearce, E.L.1
Pearce, E.J.2
-
46
-
-
84876285741
-
Succinate is an inflammatory signal that induces IL-1beta through HIF-1alpha
-
Tannahill GM, Curtis AM, Adamik J, et al. Succinate is an inflammatory signal that induces IL-1beta through HIF-1alpha. Nature 2013; 496: 238-242.
-
(2013)
Nature
, vol.496
, pp. 238-242
-
-
Tannahill, G.M.1
Curtis, A.M.2
Adamik, J.3
-
47
-
-
33745428666
-
Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation
-
Vats D,Mukundan L, Odegaard JI, et al. Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation. Cell Metab 2006; 4: 13-24.
-
(2006)
Cell Metab
, vol.4
, pp. 13-24
-
-
Vats, D.1
Mukundan, L.2
Odegaard, J.I.3
-
48
-
-
84872576236
-
Metabolism of inflammation limited by AMPK and pseudo-starvation
-
O'Neill LA, Hardie DG. Metabolism of inflammation limited by AMPK and pseudo-starvation. Nature 2013; 493: 346-355.
-
(2013)
Nature
, vol.493
, pp. 346-355
-
-
O'Neill, L.A.1
Hardie, D.G.2
-
49
-
-
84881356321
-
AMPKalpha1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration
-
Mounier R, Theret M, Arnold L, et al. AMPKalpha1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration. Cell Metab 2013; 18: 251-264.
-
(2013)
Cell Metab
, vol.18
, pp. 251-264
-
-
Mounier, R.1
Theret, M.2
Arnold, L.3
-
50
-
-
84862777909
-
Suppression of the antiviral response by an influenza histone mimic
-
Marazzi I, Ho JS, Kim J, et al. Suppression of the antiviral response by an influenza histone mimic. Nature 2012; 483: 428-433.
-
(2012)
Nature
, vol.483
, pp. 428-433
-
-
Marazzi, I.1
Ho, J.S.2
Kim, J.3
-
51
-
-
84879604583
-
Global chromatin state analysis reveals lineage-specific enhancers during the initiation of human T helper 1 and T helper 2 cell polarization
-
Hawkins RD, Larjo A, Tripathi SK, et al. Global chromatin state analysis reveals lineage-specific enhancers during the initiation of human T helper 1 and T helper 2 cell polarization. Immunity 2013; 38: 1271-1284.
-
(2013)
Immunity
, vol.38
, pp. 1271-1284
-
-
Hawkins, R.D.1
Larjo, A.2
Tripathi, S.K.3
|