메뉴 건너뛰기




Volumn 368, Issue 1620, 2013, Pages

Deciphering cis-regulatory control in inflammatory cells

Author keywords

Chromatin; Enhancers; Epigenome; Inflammation; Macrophages; Pu.1

Indexed keywords

CELL ORGANELLE; GENE EXPRESSION; GENOME; IMMUNE SYSTEM; MITOCHONDRIAL DNA; PROTEIN; SIGNAL;

EID: 84891439321     PISSN: 09628436     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rstb.2012.0370     Document Type: Article
Times cited : (14)

References (60)
  • 1
    • 77954928774 scopus 로고    scopus 로고
    • Maintaining cell identity through global control of genomic organization
    • (doi:10.1016/j.immuni.2010. 07.006)
    • Natoli G. 2010 Maintaining cell identity through global control of genomic organization. Immunity 33, 12-24. (doi:10.1016/j.immuni.2010. 07.006)
    • (2010) Immunity , vol.33 , pp. 12-24
    • Natoli, G.1
  • 2
    • 80053501181 scopus 로고    scopus 로고
    • Regulation of nucleosome landscape and transcription factor targeting at tissue-specific enhancers by BRG1
    • (doi:10.1101/gr.121145.111)
    • Hu G et al. 2011 Regulation of nucleosome landscape and transcription factor targeting at tissue-specific enhancers by BRG1. Genome Res. 21, 1650-1658. (doi:10.1101/gr.121145.111)
    • (2011) Genome Res , vol.21 , pp. 1650-1658
    • Hu, G.1
  • 3
    • 77950262538 scopus 로고    scopus 로고
    • Nucleosome dynamics define transcriptional enhancers
    • (doi:10.1038/ ng.545)
    • He HH et al. 2010 Nucleosome dynamics define transcriptional enhancers. Nat. Genet. 42, 343-347. (doi:10.1038/ ng.545)
    • (2010) Nat. Genet , vol.42 , pp. 343-347
    • He, H.H.1
  • 4
    • 39749145198 scopus 로고    scopus 로고
    • Dynamic regulation of nucleosome positioning in the human genome
    • (doi:10.1016/j.cell.2008.02.022)
    • Schones DE, Cui K, Cuddapah S, Roh TY, Barski A, Wang Z, Wei G, Zhao K. 2008 Dynamic regulation of nucleosome positioning in the human genome. Cell 132, 887-898. (doi:10.1016/j.cell.2008.02.022)
    • (2008) Cell , vol.132 , pp. 887-898
    • Schones, D.E.1    Cui, K.2    Cuddapah, S.3    Roh, T.Y.4    Barski, A.5    Wang, Z.6    Wei, G.7    Zhao, K.8
  • 5
    • 80053539409 scopus 로고    scopus 로고
    • Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity
    • (doi:10.1101/gr.121541.111)
    • Song L et al. 2011 Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity. Genome Res. 21, 1757-1767. (doi:10.1101/gr.121541.111)
    • (2011) Genome Res , vol.21 , pp. 1757-1767
    • Song, L.1
  • 6
    • 33847334699 scopus 로고    scopus 로고
    • Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
    • (doi:10.1038/ng1966)
    • Heintzman ND et al. 2007 Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat. Genet. 39, 311-318. (doi:10.1038/ng1966)
    • (2007) Nat. Genet , vol.39 , pp. 311-318
    • Heintzman, N.D.1
  • 7
    • 34249026300 scopus 로고    scopus 로고
    • Highresolution profiling of histone methylations in the human genome
    • (doi:10.1016/j. cell.2007.05.009)
    • Barski A, Cuddapah S, Cui K, Roh TY, Schones DE, Wang Z, Wei G, Chepelev I, Zhao K. 2007 Highresolution profiling of histone methylations in the human genome. Cell 129, 823-837. (doi:10.1016/j. cell.2007.05.009)
    • (2007) Cell , vol.129 , pp. 823-837
    • Barski, A.1    Cuddapah, S.2    Cui, K.3    Roh, T.Y.4    Schones, D.E.5    Wang, Z.6    Wei, G.7    Chepelev, I.8    Zhao, K.9
  • 8
    • 70249088327 scopus 로고    scopus 로고
    • Genomic views of distant-acting enhancers
    • (doi:10.1038/nature08451)
    • Visel A, Rubin EM, Pennacchio LA. 2009 Genomic views of distant-acting enhancers. Nature 461, 199-205. (doi:10.1038/nature08451)
    • (2009) Nature , vol.461 , pp. 199-205
    • Visel, A.1    Rubin, E.M.2    Pennacchio, L.A.3
  • 9
    • 78650304236 scopus 로고    scopus 로고
    • Charting histone modifications and the functional organization of mammalian genomes
    • (doi:10.1038/nrg2905)
    • Zhou VW, Goren A, Bernstein BE. 2011 Charting histone modifications and the functional organization of mammalian genomes. Nat. Rev. Genet. 12, 7-18. (doi:10.1038/nrg2905)
    • (2011) Nat. Rev. Genet , vol.12 , pp. 7-18
    • Zhou, V.W.1    Goren, A.2    Bernstein, B.E.3
  • 10
    • 77949977555 scopus 로고    scopus 로고
    • Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages
    • (doi:10. 1016/j.immuni.2010.02.008)
    • Ghisletti S et al. 2010 Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. Immunity 32, 317-328. (doi:10. 1016/j.immuni.2010.02.008)
    • (2010) Immunity , vol.32 , pp. 317-328
    • Ghisletti, S.1
  • 11
    • 60149091656 scopus 로고    scopus 로고
    • ChIP-seq accurately predicts tissue-specific activity of enhancers
    • (doi:10.1038/nature07730)
    • Visel A et al. 2009 ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature 457, 854-858. (doi:10.1038/nature07730)
    • (2009) Nature , vol.457 , pp. 854-858
    • Visel, A.1
  • 12
    • 65549104157 scopus 로고    scopus 로고
    • Histone modifications at human enhancers reflect global cell-type-specific gene expression
    • (doi:10. 1038/nature07829)
    • Heintzman ND et al. 2009 Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature 459, 108-112. (doi:10. 1038/nature07829)
    • (2009) Nature , vol.459 , pp. 108-112
    • Heintzman, N.D.1
  • 13
    • 46249112085 scopus 로고    scopus 로고
    • Combinatorial patterns of histone acetylations and methylations in the human genome
    • (doi:10.1038/ng.154)
    • Wang Z et al. 2008 Combinatorial patterns of histone acetylations and methylations in the human genome. Nat. Genet. 40, 897-903. (doi:10.1038/ng.154)
    • (2008) Nat. Genet , vol.40 , pp. 897-903
    • Wang, Z.1
  • 14
    • 79955583542 scopus 로고    scopus 로고
    • Mapping and analysis of chromatin state dynamics in nine human cell types
    • (doi:10.1038/nature09906)
    • Ernst J et al. 2011 Mapping and analysis of chromatin state dynamics in nine human cell types. Nature 473, 43-49. (doi:10.1038/nature09906)
    • (2011) Nature , vol.473 , pp. 43-49
    • Ernst, J.1
  • 15
    • 84655164920 scopus 로고    scopus 로고
    • Large-scale discovery of enhancers from human heart tissue
    • (doi:10.1038/ng.1006)
    • May D et al. 2011 Large-scale discovery of enhancers from human heart tissue. Nat. Genet. 44, 89-93. (doi:10.1038/ng.1006)
    • (2011) Nat Genet , vol.44 , pp. 89-93
    • May, D.1
  • 16
    • 33846876333 scopus 로고    scopus 로고
    • Predicting tissue-specific enhancers in the human genome
    • (doi:10.1101/gr.5972507)
    • Pennacchio LA, Loots GG, Nobrega MA, Ovcharenko I. 2007 Predicting tissue-specific enhancers in the human genome. Genome Res. 17, 201-211. (doi:10.1101/gr.5972507)
    • (2007) Genome Res , vol.17 , pp. 201-211
    • Pennacchio, L.A.1    Loots, G.G.2    Nobrega, M.A.3    Ovcharenko, I.4
  • 17
    • 77956641239 scopus 로고    scopus 로고
    • ChIP-Seq identification of weakly conserved heart enhancers
    • (doi:10.1038/ng.650)
    • Blow MJ et al. 2010 ChIP-Seq identification of weakly conserved heart enhancers. Nat. Genet. 42, 806-810. (doi:10.1038/ng.650)
    • (2010) Nat. Genet , vol.42 , pp. 806-810
    • Blow, M.J.1
  • 18
    • 84455200582 scopus 로고    scopus 로고
    • Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells
    • (doi:10.1016/j.cell.2011.09.057)
    • Ram O et al. 2011 Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells. Cell 147, 1628-1639. (doi:10.1016/j.cell.2011.09.057)
    • (2011) Cell , vol.147 , pp. 1628-1639
    • Ram, O.1
  • 19
    • 79955027617 scopus 로고    scopus 로고
    • Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart
    • (doi:10.1073/pnas. 1016959108)
    • He A, Kong SW, Ma Q, Pu WT. 2011 Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart. Proc. Natl Acad. Sci. USA 108, 5632-5637. (doi:10.1073/pnas. 1016959108)
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 5632-5637
    • He, A.1    Kong, S.W.2    Ma, Q.3    Pu, W.T.4
  • 20
    • 79955883317 scopus 로고    scopus 로고
    • Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators
    • (doi:10.1016/j. devcel.2011.04.008)
    • Tijssen MR et al. 2011 Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators. Dev. Cell 20, 597-609. (doi:10.1016/j. devcel.2011.04.008)
    • (2011) Dev Cell , vol.20 , pp. 597-609
    • Tijssen, M.R.1
  • 21
    • 84856704764 scopus 로고    scopus 로고
    • A transcription factor collective defines cardiac cell fate and reflects lineage history
    • (doi:10.1016/j.cell.2012.01.030)
    • Junion G, Spivakov M, Girardot C, Braun M, Gustafson EH, Birney E, Furlong EE. 2012 A transcription factor collective defines cardiac cell fate and reflects lineage history. Cell 148, 473-486. (doi:10.1016/j.cell.2012.01.030)
    • (2012) Cell , vol.148 , pp. 473-486
    • Junion, G.1    Spivakov, M.2    Girardot, C.3    Braun, M.4    Gustafson, E.H.5    Birney, E.6    Furlong, E.E.7
  • 22
    • 79551655285 scopus 로고    scopus 로고
    • Functional and mechanistic diversity of distal transcription enhancers
    • (doi:10.1016/j.cell. 2011.01.024)
    • Bulger M, Groudine M. 2011 Functional and mechanistic diversity of distal transcription enhancers. Cell 144, 327-339. (doi:10.1016/j.cell. 2011.01.024)
    • (2011) Cell , vol.144 , pp. 327-339
    • Bulger, M.1    Groudine, M.2
  • 23
    • 0025769412 scopus 로고
    • Primary response genes induced by growth factors and tumor promoters
    • (doi:10.1146/ annurev.bi.60.070191.001433)
    • Herschman HR. 1991 Primary response genes induced by growth factors and tumor promoters. Annu. Rev. Biochem. 60, 281-319. (doi:10.1146/ annurev.bi.60.070191.001433)
    • (1991) Annu. Rev. Biochem , vol.60 , pp. 281-319
    • Herschman, H.R.1
  • 25
    • 79959557189 scopus 로고    scopus 로고
    • Determinants of nucleosome organization in primary human cells
    • (doi:10.1038/nature10002)
    • Valouev A, Johnson SM, Boyd SD, Smith CL, Fire AZ, Sidow A. 2011 Determinants of nucleosome organization in primary human cells. Nature 474, 516-520. (doi:10.1038/nature10002)
    • (2011) Nature , vol.474 , pp. 516-520
    • Valouev, A.1    Johnson, S.M.2    Boyd, S.D.3    Smith, C.L.4    Fire, A.Z.5    Sidow, A.6
  • 26
    • 67649669255 scopus 로고    scopus 로고
    • A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling
    • (doi:10.1016/j.cell.2009. 04.020)
    • Ramirez-Carrozzi VR et al. 2009 A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling. Cell 138, 114-128. (doi:10.1016/j.cell.2009. 04.020)
    • (2009) Cell , vol.138 , pp. 114-128
    • Ramirez-Carrozzi, V.R.1
  • 27
    • 67649648237 scopus 로고    scopus 로고
    • Control of inducible gene expression by signal-dependent transcriptional elongation
    • (doi:10.1016/j.cell.2009.05.047)
    • Hargreaves DC, Horng T, Medzhitov R. 2009 Control of inducible gene expression by signal-dependent transcriptional elongation. Cell 138, 129-145. (doi:10.1016/j.cell.2009.05.047)
    • (2009) Cell , vol.138 , pp. 129-145
    • Hargreaves, D.C.1    Horng, T.2    Medzhitov, R.3
  • 28
    • 77954954652 scopus 로고    scopus 로고
    • Genome-wide analysis of ETSfamily DNA-binding in vitro and in vivo
    • (doi:10.1038/emboj.2010.106)
    • Wei GH et al. 2010 Genome-wide analysis of ETSfamily DNA-binding in vitro and in vivo. EMBO J. 29, 2147-2160. (doi:10.1038/emboj.2010.106)
    • (2010) EMBO J , vol.29 , pp. 2147-2160
    • Wei, G.H.1
  • 29
    • 0032146794 scopus 로고    scopus 로고
    • PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors
    • (doi:10. 1101/gad.12.15.2403)
    • Nerlov C, Graf T. 1998 PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors. Genes Dev. 12, 2403-2412. (doi:10. 1101/gad.12.15.2403)
    • (1998) Genes Dev , vol.12 , pp. 2403-2412
    • Nerlov, C.1    Graf, T.2
  • 30
    • 77952567987 scopus 로고    scopus 로고
    • Simple combinations of lineagedetermining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
    • (doi:10.1016/j.molcel.2010.05.004)
    • Heinz S et al. 2010 Simple combinations of lineagedetermining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 38, 576-589. (doi:10.1016/j.molcel.2010.05.004)
    • (2010) Mol Cell , vol.38 , pp. 576-589
    • Heinz, S.1
  • 32
    • 84855286273 scopus 로고    scopus 로고
    • Mechanisms establishing TLR4-responsive activation states of inflammatory response genes
    • (doi:10.1371/journal.pgen.1002401)
    • Escoubet-Lozach L et al. 2011 Mechanisms establishing TLR4-responsive activation states of inflammatory response genes. PLoS Genet. 7, e1002401. (doi:10.1371/journal.pgen.1002401)
    • (2011) PLoS Genet , vol.7
    • Escoubet-Lozach, L.1
  • 33
    • 80455144479 scopus 로고    scopus 로고
    • Pioneer transcription factors: Establishing competence for gene expression
    • (doi:10. 1101/gad.176826.111)
    • Zaret KS, Carroll JS. 2011 Pioneer transcription factors: establishing competence for gene expression. Genes Dev. 25, 2227-2241. (doi:10. 1101/gad.176826.111)
    • (2011) Genes Dev , vol.25 , pp. 2227-2241
    • Zaret, K.S.1    Carroll, J.S.2
  • 35
    • 84859582058 scopus 로고    scopus 로고
    • Genome-wide protein-DNA binding dynamics suggest a molecular clutch for transcription factor function
    • (doi:10.1038/nature10985)
    • Lickwar CR, Mueller F, Hanlon SE, McNally JG, Lieb JD. 2012 Genome-wide protein-DNA binding dynamics suggest a molecular clutch for transcription factor function. Nature 484, 251-255. (doi:10.1038/nature10985)
    • (2012) Nature , vol.484 , pp. 251-255
    • Lickwar, C.R.1    Mueller, F.2    Hanlon, S.E.3    McNally, J.G.4    Lieb, J.D.5
  • 36
    • 84866303839 scopus 로고    scopus 로고
    • A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals
    • (doi:10.1016/j.molcel.2012.07.030)
    • Garber M et al. 2012 A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals. Mol. Cell 47, 810-822. (doi:10.1016/j.molcel.2012.07.030)
    • (2012) Mol. Cell , vol.47 , pp. 810-822
    • Garber, M.1
  • 37
    • 79959198166 scopus 로고    scopus 로고
    • Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA
    • (doi:10.1038/ nature10006)
    • Wang D et al. 2011 Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA. Nature 474, 390-394. (doi:10.1038/ nature10006)
    • (2011) Nature , vol.474 , pp. 390-394
    • Wang, D.1
  • 38
    • 78651250284 scopus 로고    scopus 로고
    • FOXA1 is a key determinant of estrogen receptor function and endocrine response
    • (doi:10.1038/ng.730)
    • Hurtado A, Holmes KA, Ross-Innes CS, Schmidt D, Carroll JS. 2011 FOXA1 is a key determinant of estrogen receptor function and endocrine response. Nat. Genet. 43, 27-33. (doi:10.1038/ng.730)
    • (2011) Nat. Genet , vol.43 , pp. 27-33
    • Hurtado, A.1    Holmes, K.A.2    Ross-Innes, C.S.3    Schmidt, D.4    Carroll, J.S.5
  • 39
    • 79960072084 scopus 로고    scopus 로고
    • AP-2g regulates oestrogen receptor-mediated long-range chromatin interaction and gene transcription
    • (doi:10.1038/emboj.2011.151)
    • Tan SK, Lin ZH, Chang CW, Varang V, Chng KR, Pan YF, Yong EL, Sung WK, Cheung E. 2011 AP-2g regulates oestrogen receptor-mediated long-range chromatin interaction and gene transcription. Embo J. 30, 2569-2581. (doi:10.1038/emboj.2011.151)
    • (2011) Embo J , vol.30 , pp. 2569-2581
    • Tan, S.K.1    Lin, Z.H.2    Chang, C.W.3    Varang, V.4    Chng, K.R.5    Pan, Y.F.6    Yong, E.L.7    Sung, W.K.8    Cheung, E.9
  • 41
    • 79959911826 scopus 로고    scopus 로고
    • Transcription factor AP1 potentiates chromatin accessibility and glucocorticoid receptor binding
    • (doi:10.1016/j.molcel.2011.06.016)
    • Biddie SC et al. 2011 Transcription factor AP1 potentiates chromatin accessibility and glucocorticoid receptor binding. Mol. Cell 43, 145-155. (doi:10.1016/j.molcel.2011.06.016)
    • (2011) Mol. Cell , vol.43 , pp. 145-155
    • Biddie, S.C.1
  • 42
    • 80155137594 scopus 로고    scopus 로고
    • Master transcription factors determine cell-type-specific responses to TGF-b signaling
    • (doi:10.1016/j.cell. 2011.08.050)
    • Mullen AC et al. 2011 Master transcription factors determine cell-type-specific responses to TGF-b signaling. Cell 147, 565-576. (doi:10.1016/j.cell. 2011.08.050)
    • (2011) Cell , vol.147 , pp. 565-576
    • Mullen, A.C.1
  • 43
    • 78650758676 scopus 로고    scopus 로고
    • Histone H3K27ac separates active from poised enhancers and predicts developmental state
    • (doi:10.1073/pnas.1016071107)
    • Creyghton MP et al. 2010 Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proc. Natl Acad. Sci. USA 107, 21931-21936. (doi:10.1073/pnas.1016071107)
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 21931-21936
    • Creyghton, M.P.1
  • 44
    • 79951516056 scopus 로고    scopus 로고
    • A unique chromatin signature uncovers early developmental enhancers in humans
    • (doi:10.1038/ nature09692)
    • Rada-Iglesias A, Bajpai R, Swigut T, Brugmann SA, Flynn RA, Wysocka J. 2011 A unique chromatin signature uncovers early developmental enhancers in humans. Nature 470, 279-283. (doi:10.1038/ nature09692)
    • (2011) Nature , vol.470 , pp. 279-283
    • Rada-Iglesias, A.1    Bajpai, R.2    Swigut, T.3    Brugmann, S.A.4    Flynn, R.A.5    Wysocka, J.6
  • 45
    • 58049191558 scopus 로고    scopus 로고
    • Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation
    • (doi:10. 1016/j.stem.2008.11.011)
    • Cui K, Zang C, Roh TY, Schones DE, Childs RW, Peng W, Zhao K. 2009 Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation. Cell Stem Cell 4, 80-93. (doi:10. 1016/j.stem.2008.11.011)
    • (2009) Cell Stem Cell , vol.4 , pp. 80-93
    • Cui, K.1    Zang, C.2    Roh, T.Y.3    Schones, D.E.4    Childs, R.W.5    Peng, W.6    Zhao, K.7
  • 46
    • 80051564877 scopus 로고    scopus 로고
    • Epigenetic signatures distinguish multiple classes of enhancers with distinct cellular functions
    • (doi:10.1101/gr.122382.111)
    • Zentner GE, Tesar PJ, Scacheri PC. 2011 Epigenetic signatures distinguish multiple classes of enhancers with distinct cellular functions. Genome Res. 21, 1273-1283. (doi:10.1101/gr.122382.111)
    • (2011) Genome Res , vol.21 , pp. 1273-1283
    • Zentner, G.E.1    Tesar, P.J.2    Scacheri, P.C.3
  • 47
    • 80053131310 scopus 로고    scopus 로고
    • Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic progenitors
    • (doi:10.1016/j. immuni.2011.06.013)
    • Mercer EM et al. 2011 Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic progenitors. Immunity 35, 413-425. (doi:10.1016/j. immuni.2011.06.013)
    • (2011) Immunity , vol.35 , pp. 413-425
    • Mercer, E.M.1
  • 48
    • 84867652835 scopus 로고    scopus 로고
    • Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages
    • (doi:10.1073/ pnas.1121131109)
    • Chen X et al. 2012 Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages. Proc. Natl Acad. Sci. USA 109, E2865-E2874. (doi:10.1073/ pnas.1121131109)
    • (2012) Proc. Natl Acad. Sci. USA , vol.109
    • Chen, X.1
  • 49
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • Project Consortium et al, (doi:10. 1038/nature11247)
    • Project Consortium et al. 2012 An integrated encyclopedia of DNA elements in the human genome. ENCODE. Nature 489, 57-74. (doi:10. 1038/nature11247)
    • (2012) ENCODE. Nature , vol.489 , pp. 57-74
  • 50
    • 84865755978 scopus 로고    scopus 로고
    • The accessible chromatin landscape of the human genome
    • (doi:10.1038/ nature11232)
    • Thurman RE et al. 2012 The accessible chromatin landscape of the human genome. Nature 489, 75-82. (doi:10.1038/ nature11232)
    • (2012) Nature , vol.489 , pp. 75-82
    • Thurman, R.E.1
  • 51
    • 84865708757 scopus 로고    scopus 로고
    • An expansive human regulatory lexicon encoded in transcription factor footprints
    • (doi:10.1038/nature11212)
    • Neph S et al. 2012 An expansive human regulatory lexicon encoded in transcription factor footprints. Nature 489, 83-90. (doi:10.1038/nature11212)
    • (2012) Nature , vol.489 , pp. 83-90
    • Neph, S.1
  • 52
    • 84865739425 scopus 로고    scopus 로고
    • Architecture of the human regulatory network derived from ENCODE data
    • (doi:10.1038/nature11245)
    • Gerstein MB et al. 2012 Architecture of the human regulatory network derived from ENCODE data. Nature 489, 91-100. (doi:10.1038/nature11245)
    • (2012) Nature , vol.489 , pp. 91-100
    • Gerstein, M.B.1
  • 53
    • 77952908743 scopus 로고    scopus 로고
    • A large fraction of extragenic RNA pol II transcription sites overlap enhancers
    • (doi:10.1371/journal.pbio.1000384)
    • De Santa F et al. 2010 A large fraction of extragenic RNA pol II transcription sites overlap enhancers. PLoS Biol. 8, e1000384. (doi:10.1371/journal.pbio.1000384)
    • (2010) PLoS Biol , vol.8
    • de Santa, F.1
  • 54
    • 84861904178 scopus 로고    scopus 로고
    • Genome regulation by long noncoding RNAs
    • (doi:10.1146/annurev-biochem-051410- 092902)
    • Rinn JL, Chang HY. 2012 Genome regulation by long noncoding RNAs. Annu. Rev. Biochem. 81, 145-166. (doi:10.1146/annurev-biochem-051410- 092902)
    • (2012) Annu Rev. Biochem , vol.81 , pp. 145-166
    • Rinn, J.L.1    Chang, H.Y.2
  • 55
    • 84870182699 scopus 로고    scopus 로고
    • Noncoding transcription at enhancers: General principles and functional models
    • (doi:10.1146/ annurev-genet-110711-155459)
    • Natoli G, Andrau JC. 2012 Noncoding transcription at enhancers: general principles and functional models. Annu. Rev. Genet. 46, 1-19. (doi:10.1146/ annurev-genet-110711-155459)
    • (2012) Annu. Rev. Genet , vol.46 , pp. 1-19
    • Natoli, G.1    Andrau, J.C.2
  • 56
    • 77952367798 scopus 로고    scopus 로고
    • Widespread transcription at neuronal activity-regulated enhancers
    • (doi:10.1038/nature09033)
    • Kim TK et al. 2010 Widespread transcription at neuronal activity-regulated enhancers. Nature 465, 182-187. (doi:10.1038/nature09033)
    • (2010) Nature , vol.465 , pp. 182-187
    • Kim, T.K.1
  • 57
    • 84861964135 scopus 로고    scopus 로고
    • Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor
    • (doi:10.1016/j.cell.2012.03.051)
    • Deng W, Lee J, Wang H, Miller J, Reik A, Gregory PD, Dean A, Blobel GA. 2012 Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor. Cell 149, 1233-1244. (doi:10.1016/j.cell.2012.03.051)
    • (2012) Cell , vol.149 , pp. 1233-1244
    • Deng, W.1    Lee, J.2    Wang, H.3    Miller, J.4    Reik, A.5    Gregory, P.D.6    Dean, A.7    Blobel, G.A.8
  • 58
    • 80054702528 scopus 로고    scopus 로고
    • Two forms of loops generate the chromatin conformation of the immunoglobulin heavy-chain gene locus
    • (doi:10.1016/j.cell.2011.08.049)
    • Guo C, Gerasimova T, Hao H, Ivanova I, Chakraborty T, Selimyan R, Oltz EM, Sen R. 2011 Two forms of loops generate the chromatin conformation of the immunoglobulin heavy-chain gene locus. Cell 147, 332-343. (doi:10.1016/j.cell.2011.08.049)
    • (2011) Cell , vol.147 , pp. 332-343
    • Guo, C.1    Gerasimova, T.2    Hao, H.3    Ivanova, I.4    Chakraborty, T.5    Selimyan, R.6    Oltz, E.M.7    Sen, R.8
  • 59
    • 3543018516 scopus 로고    scopus 로고
    • Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parentspecific chromatin loops
    • (doi:10.1038/ng1402)
    • Murrell A, Heeson S, Reik W. 2004 Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parentspecific chromatin loops. Nat. Genet. 36, 889-893. (doi:10.1038/ng1402)
    • (2004) Nat. Genet , vol.36 , pp. 889-893
    • Murrell, A.1    Heeson, S.2    Reik, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.