메뉴 건너뛰기




Volumn 6, Issue 5, 2014, Pages 1133-1144

Regulation of complement and modulation of its activity in monoclonal antibody therapy of cancer

Author keywords

[No Author keywords available]

Indexed keywords

CD59 ANTIGEN; CLUSTERIN; COMPLEMENT; COMPLEMENT COMPONENT C1S INHIBITOR; COMPLEMENT COMPONENT C3B RECEPTOR; COMPLEMENT COMPONENT C4B BINDING PROTEIN; COMPLEMENT FACTOR H; DECAY ACCELERATING FACTOR; MEMBRANE COFACTOR PROTEIN; MONOCLONAL ANTIBODY; VITRONECTIN;

EID: 84913603159     PISSN: 19420862     EISSN: 19420870     Source Type: Journal    
DOI: 10.4161/mabs.29670     Document Type: Review
Times cited : (90)

References (119)
  • 1
    • 76249096572 scopus 로고    scopus 로고
    • Complement: Help or hindrance?
    • author reply 5568 PMID:20035044
    • Beers SA, Cragg MS, Glennie MJ. Complement: help or hindrance? Blood 2009; 114:5567-8, author reply 5568; PMID:20035044; http://dx.doi.org/10.1182/ blood-2009-10-249466
    • (2009) Blood , vol.114 , pp. 5567-5568
    • Beers, S.A.1    Cragg, M.S.2    Glennie, M.J.3
  • 2
    • 77950389177 scopus 로고    scopus 로고
    • Complement in antibody therapy: Friend or foe?
    • PMID:20018922
    • Introna M, Golay J. Complement in antibody therapy: friend or foe? Blood 2009; 114:5247-8; PMID:20018922; http://dx.doi.org/10.1182/blood-2009-10-249532
    • (2009) Blood , vol.114 , pp. 5247-5248
    • Introna, M.1    Golay, J.2
  • 3
    • 84891629992 scopus 로고    scopus 로고
    • The role of complement in mAb-based therapies of cancer
    • PMID:23886909
    • Taylor RP, Lindorfer MA. The role of complement in mAb-based therapies of cancer. Methods 2014; 65:18-27; PMID:23886909; http://dx.doi.org/ 10.1016/j.ymeth.2013.07.027
    • (2014) Methods , vol.65 , pp. 18-27
    • Taylor, R.P.1    Lindorfer, M.A.2
  • 4
    • 34347328055 scopus 로고    scopus 로고
    • Complement as effector system in cancer immunotherapy
    • PMID:17572509
    • Macor P, Tedesco F. Complement as effector system in cancer immunotherapy. Immunol Lett 2007; 111:6-13; PMID:17572509; http://dx.doi.org/ 10.1016/j.imlet.2007.04.014
    • (2007) Immunol Lett , vol.111 , pp. 6-13
    • Macor, P.1    Tedesco, F.2
  • 5
    • 84896970663 scopus 로고    scopus 로고
    • Complement and its receptors: New insights into human disease
    • PMID:24499275
    • Holers VM. Complement and its receptors: new insights into human disease. Annu Rev Immunol 2014; 32:433-59; PMID:24499275; http://dx.doi. org/10.1146/annurev-immunol-032713-120154
    • (2014) Annu Rev Immunol , vol.32 , pp. 433-459
    • Holers, V.M.1
  • 6
    • 74149086780 scopus 로고    scopus 로고
    • Therapeutic potential of complement modulation
    • PMID:19960015
    • Wagner E, Frank MM. Therapeutic potential of complement modulation. Nat Rev Drug Discov 2010; 9:43-56; PMID:19960015; http://dx.doi.org/ 10.1038/nrd3011
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 43-56
    • Wagner, E.1    Frank, M.M.2
  • 7
    • 33645953014 scopus 로고    scopus 로고
    • Crosslinking tumor cells with effector cells via CD55 with a bispecific mAb induces beta-glucan-dependent CR3-dependent cellular cytotoxicity
    • PMID:16525993
    • Gelderman KA, Lam S, Sier CF, Gorter A. Crosslinking tumor cells with effector cells via CD55 with a bispecific mAb induces beta-glucan-dependent CR3-dependent cellular cytotoxicity. Eur J Immunol 2006; 36:977-84; PMID:16525993; http://dx.doi.org/ 10.1002/eji.200535653
    • (2006) Eur J Immunol , vol.36 , pp. 977-984
    • Gelderman, K.A.1    Lam, S.2    Sier, C.F.3    Gorter, A.4
  • 9
    • 0036945832 scopus 로고    scopus 로고
    • C5a anaphylatoxin is a major regulator of activating versus inhibitory FcgammaRs in immune complex-induced lung disease
    • PMID: 12488432
    • Shushakova N, Skokowa J, Schulman J, Baumann U, Zwirner J, Schmidt RE, Gessner JE. C5a anaphylatoxin is a major regulator of activating versus inhibitory FcgammaRs in immune complex-induced lung disease. J Clin Invest 2002; 110:1823-30; PMID: 12488432; http://dx.doi.org/10.1172/JCI16577
    • (2002) J Clin Invest , vol.110 , pp. 1823-1830
    • Shushakova, N.1    Skokowa, J.2    Schulman, J.3    Baumann, U.4    Zwirner, J.5    Schmidt, R.E.6    Gessner, J.E.7
  • 10
    • 0031954632 scopus 로고    scopus 로고
    • A newly discovered function for C1 inhibitor, removal of the entire C1qr2s2 complex from immobilized human IgG subclasses
    • PMID: 9576012
    • Chen CH, Boackle RJ. A newly discovered function for C1 inhibitor, removal of the entire C1qr2s2 complex from immobilized human IgG subclasses. Clin Immunol Immunopathol 1998; 87:68-74; PMID: 9576012; http://dx.doi.org/10.1006/clin.1997.4515
    • (1998) Clin Immunol Immunopathol , vol.87 , pp. 68-74
    • Chen, C.H.1    Boackle, R.J.2
  • 11
    • 0035125698 scopus 로고    scopus 로고
    • A review of the reported defects in the human C1 esterase inhibitor gene producing hereditary angioedema including four new mutations
    • PMID:11161971
    • Bowen B, Hawk JJ, Sibunka S, Hovick S, Weiler JM. A review of the reported defects in the human C1 esterase inhibitor gene producing hereditary angioedema including four new mutations. Clin Immunol 2001; 98:157-63; PMID:11161971; http:// dx.doi.org/10.1006/clim.2000.4947
    • (2001) Clin Immunol , vol.98 , pp. 157-163
    • Bowen, B.1    Hawk, J.J.2    Sibunka, S.3    Hovick, S.4    Weiler, J.M.5
  • 12
    • 60949104520 scopus 로고    scopus 로고
    • C1-inhibitor deficiency and angioedema: Molecular mechanisms and clinical progress
    • PMID:19162547
    • Cugno M, Zanichelli A, Foieni F, Caccia S, Cicardi M. C1-inhibitor deficiency and angioedema: molecular mechanisms and clinical progress. Trends Mol Med 2009; 15:69-78; PMID:19162547; http://dx. doi.org/10.1016/j.molmed.2008.12.001
    • (2009) Trends Mol Med , vol.15 , pp. 69-78
    • Cugno, M.1    Zanichelli, A.2    Foieni, F.3    Caccia, S.4    Cicardi, M.5
  • 14
    • 84861727429 scopus 로고    scopus 로고
    • A Complement Regulator in Health and Disease, and a Mediator of Cellular Interactions
    • Kopp A, Hebecker M, Svobodov-a E, J-ozsi M, Factor H. A Complement Regulator in Health and Disease, and a Mediator of Cellular Interactions. Biomolecules 2012; 2:46-75; http://dx.doi.org/10.3390/biom2010 046
    • (2012) Biomolecules , vol.2 , pp. 46-75
    • Kopp, A.1    Hebecker, M.2    Svobodová, E.3    Józsi, M.4    Factor, H.5
  • 15
    • 0034040022 scopus 로고    scopus 로고
    • Exceptional resistance of human H2 glioblastoma cells to complement-mediated killing by expression and utilization of factor H and factor Hlike protein 1
    • PMID:10820293
    • Junnikkala S, Jokiranta TS, Friese MA, Jarva H, Zipfel PF, Meri S. Exceptional resistance of human H2 glioblastoma cells to complement-mediated killing by expression and utilization of factor H and factor Hlike protein 1. J Immunol 2000; 164:6075-81; PMID:10820293; http://dx.doi.org/10.4049/jimmu nol.164.11.6075
    • (2000) J Immunol , vol.164 , pp. 6075-6081
    • Junnikkala, S.1    Jokiranta, T.S.2    Friese, M.A.3    Jarva, H.4    Zipfel, P.F.5    Meri, S.6
  • 17
    • 44449103295 scopus 로고    scopus 로고
    • A novel non-synonymous polymorphism (p.Arg240His) in C4b-binding protein is associated with atypical hemolytic uremic syndrome and leads to impaired alternative pathway cofactor activity
    • PMID:18424762
    • Blom AM, Bergstrom F, Edey M, Diaz-Torres M, Kavanagh D, Lampe A, Goodship JA, Strain L, Moghal N, McHugh M, et al. A novel non-synonymous polymorphism (p.Arg240His) in C4b-binding protein is associated with atypical hemolytic uremic syndrome and leads to impaired alternative pathway cofactor activity. J Immunol 2008; 180:6385-91; PMID:18424762; http://dx.doi.org/10.4049/jimmu nol.180.9.6385
    • (2008) J Immunol , vol.180 , pp. 6385-6391
    • Blom, A.M.1    Bergstrom, F.2    Edey, M.3    Diaz-Torres, M.4    Kavanagh, D.5    Lampe, A.6    Goodship, J.A.7    Strain, L.8    Moghal, N.9    McHugh, M.10
  • 19
    • 0033602717 scopus 로고    scopus 로고
    • Easter-brook-Smith SB. A reexamination of the role of clusterin as a complement regulator
    • PMID:10328949
    • Hochgrebe TT, Humphreys D, Wilson MR, Easter-brook-Smith SB. A reexamination of the role of clusterin as a complement regulator. Exp Cell Res 1999; 249:13-21; PMID:10328949; http://dx.doi.org/10.10 06/excr.1999.4459
    • (1999) Exp Cell Res , vol.249 , pp. 13-21
    • Hochgrebe, T.T.1    Humphreys, D.2    Wilson, M.R.3
  • 20
    • 0026334978 scopus 로고
    • Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells
    • PMID:1721625
    • Gladson CL, Cheresh DA. Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells. J Clin Invest 1991; 88:1924-32; PMID:1721625; http://dx.doi. org/10.1172/JCI115516
    • (1991) J Clin Invest , vol.88 , pp. 1924-1932
    • Gladson, C.L.1    Cheresh, D.A.2
  • 21
    • 70449120924 scopus 로고    scopus 로고
    • The structure, genetic polymorphisms, expression and biological functions of complement receptor type 1 (CR1/CD35)
    • PMID:19874218
    • Liu D, Niu ZX. The structure, genetic polymorphisms, expression and biological functions of complement receptor type 1 (CR1/CD35). Immunopharmacol Immunotoxicol 2009; 31:524-35; PMID:19874218; http://dx.doi.org/10.3109/08923 970902845768
    • (2009) Immunopharmacol Immunotoxicol , vol.31 , pp. 524-535
    • Liu, D.1    Niu, Z.X.2
  • 23
    • 68049123124 scopus 로고    scopus 로고
    • Complement in human diseases: Lessons from complement deficiencies
    • PMID:19481265
    • Botto M, Kirschfink M, Macor P, Pickering MC, Wurzner R, Tedesco F. Complement in human diseases: Lessons from complement deficiencies. Mol Immunol 2009; 46:2774-83; PMID:19481265; http://dx.doi.org/10.1016/j.molimm.2009.04.029
    • (2009) Mol Immunol , vol.46 , pp. 2774-2783
    • Botto, M.1    Kirschfink, M.2    Macor, P.3    Pickering, M.C.4    Wurzner, R.5    Tedesco, F.6
  • 24
    • 0037021263 scopus 로고    scopus 로고
    • Secretion of soluble complement inhibitors factor H and factor Hlike protein (FHL-1) by ovarian tumour cells
    • PMID:12402151
    • Junnikkala S, Hakulinen J, Jarva H, Manuelian T, Bjørge L, Butzow R, Zipfel PF, Meri S. Secretion of soluble complement inhibitors factor H and factor Hlike protein (FHL-1) by ovarian tumour cells. Br J Cancer 2002; 87:1119-27; PMID:12402151; http:// dx.doi.org/10.1038/sj.bjc.6600614
    • (2002) Br J Cancer , vol.87 , pp. 1119-1127
    • Junnikkala, S.1    Hakulinen, J.2    Jarva, H.3    Manuelian, T.4    Bjørge, L.5    Butzow, R.6    Zipfel, P.F.7    Meri, S.8
  • 25
    • 4344689094 scopus 로고    scopus 로고
    • Expression of complement factor H by lung cancer cells: Effects on the activation of the alternative pathway of complement
    • PMID:15342420
    • Ajona D, Castaño Z, Garayoa M, Zudaire E, Pajares MJ, Martinez A, Cuttitta F, Montuenga LM, Pio R. Expression of complement factor H by lung cancer cells: effects on the activation of the alternative pathway of complement. Cancer Res 2004; 64:6310-8; PMID:15342420; http://dx.doi.org/10.1158/0008-5472.CAN-03-2328
    • (2004) Cancer Res , vol.64 , pp. 6310-6318
    • Ajona, D.1    Castañ O, Z.2    Garayoa, M.3    Zudaire, E.4    Pajares, M.J.5    Martinez, A.6    Cuttitta, F.7    Montuenga, L.M.8    Pio, R.9
  • 28
    • 0028366242 scopus 로고
    • Gp80 (clusterin; TRPM-2) mRNA level is enhanced in human renal clear cell carcinomas
    • PMID:8263017
    • Parczyk K, Pilarsky C, Rachel U, Koch-Brandt C. Gp80 (clusterin; TRPM-2) mRNA level is enhanced in human renal clear cell carcinomas. J Cancer Res Clin Oncol 1994; 120:186-8; PMID:8263017; http://dx.doi.org/10.1007/BF01202200
    • (1994) J Cancer Res Clin Oncol , vol.120 , pp. 186-188
    • Parczyk, K.1    Pilarsky, C.2    Rachel, U.3    Koch-Brandt, C.4
  • 30
    • 0027459279 scopus 로고
    • Expression of messenger RNAs for complement inhibitors in human tissues and tumors
    • PMID:7678074
    • Kumar S, Vinci JM, Pytel BA, Baglioni C. Expression of messenger RNAs for complement inhibitors in human tissues and tumors. Cancer Res 1993; 53:348-53; PMID:7678074
    • (1993) Cancer Res , vol.53 , pp. 348-353
    • Kumar, S.1    Vinci, J.M.2    Pytel, B.A.3    Baglioni, C.4
  • 31
    • 0034779990 scopus 로고    scopus 로고
    • Downregulation of clusterin expression in testicular germ cell tumours
    • PMID: 11641613
    • Behrens P, Jeske W, Wernert N, Wellmann A. Downregulation of clusterin expression in testicular germ cell tumours. Pathobiology 2001; 69:19-23; PMID: 11641613; http://dx.doi.org/10.1159/000048753
    • (2001) Pathobiology , vol.69 , pp. 19-23
    • Behrens, P.1    Jeske, W.2    Wernert, N.3    Wellmann, A.4
  • 32
    • 0033903190 scopus 로고    scopus 로고
    • Overexpression of clusterin in human breast carcinoma
    • PMID:10934144
    • Redondo M, Villar E, Torres-Muñoz J, Tellez T, Morell M, Petito CK. Overexpression of clusterin in human breast carcinoma. Am J Pathol 2000; 157: 393-9; PMID:10934144; http://dx.doi.org/10.1016/ S0002-9440(10)64552-X
    • (2000) Am J Pathol , vol.157 , pp. 393-399
    • Redondo, M.1    Villar, E.2    Torres-Muñ Oz, J.3    Tellez, T.4    Morell, M.5    Petito, C.K.6
  • 33
    • 0036829661 scopus 로고    scopus 로고
    • Clusterin/apolipoprotein J in human aging and cancer
    • PMID:12200037
    • Trougakos IP, Gonos ES. Clusterin/apolipoprotein J in human aging and cancer. Int J Biochem Cell Biol 2002; 34:1430-48; PMID:12200037; http://dx.doi. org/10.1016/S1357-2725(02)00041-9
    • (2002) Int J Biochem Cell Biol , vol.34 , pp. 1430-1448
    • Trougakos, I.P.1    Gonos, E.S.2
  • 34
    • 0027322919 scopus 로고
    • Vitronectin secretion by hepatic and non-hepatic human cancer cells
    • PMID:7686142
    • Yasumitsu H, Seo N, Misugi E, Morita H, Miyazaki K, Umeda M. Vitronectin secretion by hepatic and non-hepatic human cancer cells. In Vitro Cell Dev Biol Anim 1993; 29A:403-7; PMID:7686142; http:// dx.doi.org/10.1007/BF02633989
    • (1993) Vitro Cell Dev Biol Anim , vol.29 , pp. 403-407
    • Yasumitsu, H.1    Seo, N.2    Misugi, E.3    Morita, H.4    Miyazaki, K.5    Umeda, M.6
  • 36
    • 0028345773 scopus 로고
    • Distribution of C3-step regulatory proteins of the complement system, CD35 (CR1), CD46 (MCP), and CD55 (DAF), in hematological malignancies
    • PMID:7514063
    • Seya T, Matsumoto M, Hara T, Hatanaka M, Masaoka T, Akedo H. Distribution of C3-step regulatory proteins of the complement system, CD35 (CR1), CD46 (MCP), and CD55 (DAF), in hematological malignancies. Leuk Lymphoma 1994; 12:395-400; PMID:7514063; http://dx.doi.org/10.3109/ 10428199409073780
    • (1994) Leuk Lymphoma , vol.12 , pp. 395-400
    • Seya, T.1    Matsumoto, M.2    Hara, T.3    Hatanaka, M.4    Masaoka, T.5    Akedo, H.6
  • 37
    • 0029900739 scopus 로고    scopus 로고
    • Human carcinomas variably express the complement inhibitory proteins CD46 (membrane cofactor protein), CD55 (decay-accelerating factor), and CD59 (protectin)
    • PMID:8686736
    • Niehans GA, Cherwitz DL, Staley NA, Knapp DJ, Dalmasso AP. Human carcinomas variably express the complement inhibitory proteins CD46 (membrane cofactor protein), CD55 (decay-accelerating factor), and CD59 (protectin). Am J Pathol 1996; 149:129-42; PMID:8686736
    • (1996) Am J Pathol , vol.149 , pp. 129-142
    • Niehans, G.A.1    Cherwitz, D.L.2    Staley, N.A.3    Knapp, D.J.4    Dalmasso, A.P.5
  • 38
    • 0037316424 scopus 로고    scopus 로고
    • Complement resistance of human carcinoma cells depends on membrane regulatory proteins, protein kinases and sialic acid
    • PMID:12562385
    • Donin N, Jurianz K, Ziporen L, Schultz S, Kirschfink M, Fishelson Z. Complement resistance of human carcinoma cells depends on membrane regulatory proteins, protein kinases and sialic acid. Clin Exp Immunol 2003; 131:254-63; PMID:12562385; http://dx. doi.org/10.1046/j.1365-2249.2003.02066.x
    • (2003) Clin Exp Immunol , vol.131 , pp. 254-263
    • Donin, N.1    Jurianz, K.2    Ziporen, L.3    Schultz, S.4    Kirschfink, M.5    Fishelson, Z.6
  • 39
    • 0033777815 scopus 로고    scopus 로고
    • Overexpression of protectin (CD59) down-modulates the susceptibility of human melanoma cells to homologous complement
    • PMID:11056001
    • Coral S, Fonsatti E, Sigalotti L, De Nardo C, Visintin A, Nardi G, Colizzi F, Colombo MP, Romano G, Altomonte M, et al. Overexpression of protectin (CD59) down-modulates the susceptibility of human melanoma cells to homologous complement. J Cell Physiol 2000; 185:317-23; PMID:11056001; http:// dx.doi.org/10.1002/1097-4652(200012)185:3<317:: AID-JCP1>3.0.CO;2-L
    • (2000) J Cell Physiol , vol.185 , pp. 317-323
    • Coral, S.1    Fonsatti, E.2    Sigalotti, L.3    De Nardo, C.4    Visintin, A.5    Nardi, G.6    Colizzi, F.7    Colombo, M.P.8    Romano, G.9    Altomonte, M.10
  • 40
    • 0043025142 scopus 로고    scopus 로고
    • Loss of CD59 expression in breast tumours correlates with poor survival
    • PMID:12898600
    • Madjd Z, Pinder SE, Paish C, Ellis IO, Carmichael J, Durrant LG. Loss of CD59 expression in breast tumours correlates with poor survival. J Pathol 2003; 200:633-9; PMID:12898600; http://dx.doi.org/ 10.1002/path.1357
    • (2003) J Pathol , vol.200 , pp. 633-639
    • Madjd, Z.1    Pinder, S.E.2    Paish, C.3    Ellis, I.O.4    Carmichael, J.5    Durrant, L.G.6
  • 41
    • 0027420740 scopus 로고
    • Expression of CD59, a complement regulator protein and a second ligand of the CD2 molecule, and CD46 in normal and neoplastic colorectal epithelium
    • PMID:7692919
    • Koretz K, Bruderlein S, Henne C, Moller P. Expression of CD59, a complement regulator protein and a second ligand of the CD2 molecule, and CD46 in normal and neoplastic colorectal epithelium. Br J Cancer 1993; 68:926-31; PMID:7692919; http://dx. doi.org/10.1038/bjc.1993.456
    • (1993) Br J Cancer , vol.68 , pp. 926-931
    • Koretz, K.1    Bruderlein, S.2    Henne, C.3    Moller, P.4
  • 42
    • 33646416462 scopus 로고    scopus 로고
    • Inhibition of decay-accelerating factor (CD55) attenuates prostate cancer growth and survival in vivo
    • PMID:16533428
    • Loberg RD, Day LL, Dunn R, Kalikin LM, Pienta KJ. Inhibition of decay-accelerating factor (CD55) attenuates prostate cancer growth and survival in vivo. Neoplasia 2006; 8:69-78; PMID:16533428; http:// dx.doi.org/10.1593/neo.05679
    • (2006) Neoplasia , vol.8 , pp. 69-78
    • Loberg, R.D.1    Day, L.L.2    Dunn, R.3    Kalikin, L.M.4    Pienta, K.J.5
  • 43
    • 0142042497 scopus 로고    scopus 로고
    • Enhanced expression of the complement regulatory protein CD55 predicts a poor prognosis in colorectal cancer patients
    • PMID: 12811528
    • Durrant LG, Chapman MA, Buckley DJ, Spendlove I, Robins RA, Armitage NC. Enhanced expression of the complement regulatory protein CD55 predicts a poor prognosis in colorectal cancer patients. Cancer Immunol Immunother 2003; 52:638-42; PMID: 12811528; http://dx.doi.org/10.1007/s00262-003-0402-y
    • (2003) Cancer Immunol Immunother , vol.52 , pp. 638-642
    • Durrant, L.G.1    Chapman, M.A.2    Buckley, D.J.3    Spendlove, I.4    Robins, R.A.5    Armitage, N.C.6
  • 44
    • 0034033511 scopus 로고    scopus 로고
    • A possible role of CD46 for the protection in vivo of human renal tumor cells from complement-mediated damage
    • PMID:10744069
    • Blok VT, Daha MR, Tijsma OM, Weissglas MG, van den Broek LJ, Gorter A. A possible role of CD46 for the protection in vivo of human renal tumor cells from complement-mediated damage. Lab Invest 2000; 80:335-44; PMID:10744069; http://dx.doi. org/10.1038/labinvest.3780038
    • (2000) Lab Invest , vol.80 , pp. 335-344
    • Blok, V.T.1    Daha, M.R.2    Tijsma, O.M.3    Weissglas, M.G.4    Van Den Broek, L.J.5    Gorter, A.6
  • 46
    • 0035760902 scopus 로고    scopus 로고
    • CD20 levels determine the in vitro susceptibility to rituximab and complement of B-cell chronic lymphocytic leukemia: F urther regulation by CD55 and CD59
    • PMID:11719378
    • Golay J, Lazzari M, Facchinetti V, Bernasconi S, Borleri G, Barbui T, Rambaldi A, Introna M. CD20 levels determine the in vitro susceptibility to rituximab and complement of B-cell chronic lymphocytic leukemia: further regulation by CD55 and CD59. Blood 2001; 98:3383-9; PMID:11719378; http://dx.doi. org/10.1182/blood.V98.12.3383
    • (2001) Blood , vol.98 , pp. 3383-3389
    • Golay, J.1    Lazzari, M.2    Facchinetti, V.3    Bernasconi, S.4    Borleri, G.5    Barbui, T.6    Rambaldi, A.7    Introna, M.8
  • 47
    • 0036273631 scopus 로고    scopus 로고
    • Expression of Complement Regulating Factors in Gastric Cancer Cells
    • PMID:12032231
    • Inoue T, Yamakawa M, Takahashi T. Expression of complement regulating factors in gastric cancer cells. Mol Pathol 2002; 55:193-9; PMID:12032231; http://dx.doi.org/10.1136/mp.55.3.193
    • (2002) Mol Pathol , vol.55 , pp. 193-199
    • Inoue, T.1    Yamakawa, M.2    Takahashi, T.3
  • 48
    • 0033974021 scopus 로고    scopus 로고
    • Expression of complement regulatory proteins-CD 35, CD 46, CD 55, and CD 59-in benign and malignant endometrial tissue
    • PMID: 10637067
    • Murray KP, Mathure S, Kaul R, Khan S, Carson LF, Twiggs LB, Martens MG, Kaul A. Expression of complement regulatory proteins-CD 35, CD 46, CD 55, and CD 59-in benign and malignant endometrial tissue. Gynecol Oncol 2000; 76:176-82; PMID: 10637067; http://dx.doi.org/10.1006/gyno.1999. 5614
    • (2000) Gynecol Oncol , vol.76 , pp. 176-182
    • Murray, K.P.1    Mathure, S.2    Kaul, R.3    Khan, S.4    Carson, L.F.5    Twiggs, L.B.6    Martens, M.G.7    Kaul, A.8
  • 49
    • 4444343395 scopus 로고    scopus 로고
    • Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas
    • PMID:15172969
    • Teeling JL, French RR, Cragg MS, van den Brakel J, Pluyter M, Huang H, Chan C, Parren PW, Hack CE, Dechant M, et al. Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas. Blood 2004; 104:1793-800; PMID:15172969; http://dx. doi.org/10.1182/blood-2004-01-0039
    • (2004) Blood , vol.104 , pp. 1793-1800
    • Teeling, J.L.1    French, R.R.2    Cragg, M.S.3    Van Den Brakel, J.4    Pluyter, M.5    Huang, H.6    Chan, C.7    Parren, P.W.8    Hack, C.E.9    Dechant, M.10
  • 50
    • 84871831846 scopus 로고    scopus 로고
    • Ofatumumab is more efficient than rituximab in lysing B chronic lymphocytic leukemia cells in whole blood and in combination with chemotherapy
    • PMID:23225880
    • Bologna L, Gotti E, Da Roit F, Intermesoli T, Rambaldi A, Introna M, Golay J. Ofatumumab is more efficient than rituximab in lysing B chronic lymphocytic leukemia cells in whole blood and in combination with chemotherapy. J Immunol 2013; 190:231-9; PMID:23225880; http://dx.doi.org/10.4049/ jimmunol.1202645
    • (2013) J Immunol , vol.190 , pp. 231-239
    • Bologna, L.1    Gotti, E.2    Da Roit, F.3    Intermesoli, T.4    Rambaldi, A.5    Introna, M.6    Golay, J.7
  • 51
    • 84867178829 scopus 로고    scopus 로고
    • Complement dependent cytotoxicity in chronic lymphocytic leukemia: Ofatumumab enhances alemtuzumab complement dependent cytotoxicity and reveals cells resistant to activated complement
    • PMID:22475085
    • Baig NA, Taylor RP, Lindorfer MA, Church AK, Laplant BR, Pavey ES, Nowakowski GS, Zent CS. Complement dependent cytotoxicity in chronic lymphocytic leukemia: ofatumumab enhances alemtuzumab complement dependent cytotoxicity and reveals cells resistant to activated complement. Leuk Lymphoma 2012; 53:2218-27; PMID:22475085; http:// dx.doi.org/10.3109/10428194.2012.681657
    • (2012) Leuk Lymphoma , vol.53 , pp. 2218-2227
    • Baig, N.A.1    Taylor, R.P.2    Lindorfer, M.A.3    Church, A.K.4    Laplant, B.R.5    Pavey, E.S.6    Nowakowski, G.S.7    Zent, C.S.8
  • 52
    • 79953183947 scopus 로고    scopus 로고
    • Mechanism of action of type II, glycoengineered, anti-CD20 monoclonal antibody GA101 in B-chronic lymphocytic leukemia whole blood assays in comparison with rituximab and alemtuzumab
    • PMID:21296976
    • Bologna L, Gotti E, Manganini M, Rambaldi A, Intermesoli T, Introna M, Golay J. Mechanism of action of type II, glycoengineered, anti-CD20 monoclonal antibody GA101 in B-chronic lymphocytic leukemia whole blood assays in comparison with rituximab and alemtuzumab. J Immunol 2011; 186:3762-9; PMID:21296976; http://dx.doi.org/ 10.4049/jimmunol.1000303
    • (2011) J Immunol , vol.186 , pp. 3762-3769
    • Bologna, L.1    Gotti, E.2    Manganini, M.3    Rambaldi, A.4    Intermesoli, T.5    Introna, M.6    Golay, J.7
  • 53
    • 19744361832 scopus 로고    scopus 로고
    • Effect of alemtuzumab on neoplastic B cells
    • PMID:15590398
    • Golay J, Manganini M, Rambaldi A, Introna M. Effect of alemtuzumab on neoplastic B cells. Haematologica 2004; 89:1476-83; PMID:15590398
    • (2004) Haematologica , vol.89 , pp. 1476-1483
    • Golay, J.1    Manganini, M.2    Rambaldi, A.3    Introna, M.4
  • 54
    • 1842507429 scopus 로고    scopus 로고
    • Alemtuzumab (CAMPATH 1H) does not kill chronic lymphocytic leukemia cells in serum free medium
    • PMID:15068903
    • Zent CS, Chen JB, Kurten RC, Kaushal GP, Lacy HM, Schichman SA. Alemtuzumab (CAMPATH 1H) does not kill chronic lymphocytic leukemia cells in serum free medium. Leuk Res 2004; 28:495-507; PMID:15068903; http://dx.doi.org/10.1016/j.leukres. 2003.09.011
    • (2004) Leuk Res , vol.28 , pp. 495-507
    • Zent, C.S.1    Chen, J.B.2    Kurten, R.C.3    Kaushal, G.P.4    Lacy, H.M.5    Schichman, S.A.6
  • 55
    • 0020835433 scopus 로고
    • Effects of monoclonal anti-lymphocyte antibodies in vivo in monkeys and humans
    • PMID:6438435
    • Hale G, Swirsky DM, Hayhoe FG, Waldmann H. Effects of monoclonal anti-lymphocyte antibodies in vivo in monkeys and humans. Mol Biol Med 1983; 1:321-34; PMID:6438435
    • (1983) Mol Biol Med , vol.1 , pp. 321-334
    • Hale, G.1    Swirsky, D.M.2    Hayhoe, F.G.3    Waldmann, H.4
  • 56
    • 0024566393 scopus 로고
    • Effects of CAMPATH-1 antibodies in vivo in patients with lymphoid malignancies: Influence of antibody isotype
    • PMID:2713487
    • Dyer MJ, Hale G, Hayhoe FG, Waldmann H. Effects of CAMPATH-1 antibodies in vivo in patients with lymphoid malignancies: influence of antibody isotype. Blood 1989; 73:1431-9; PMID:2713487
    • (1989) Blood , vol.73 , pp. 1431-1439
    • Dyer, M.J.1    Hale, G.2    Hayhoe, F.G.3    Waldmann, H.4
  • 57
    • 79251570884 scopus 로고    scopus 로고
    • Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors
    • PMID: 21187443
    • de Weers M, Tai YT, van der Veer MS, Bakker JM, Vink T, Jacobs DC, Oomen LA, Peipp M, Valerius T, Slootstra JW, et al. Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors. J Immunol 2011; 186:1840-8; PMID: 21187443; http://dx.doi.org/10.4049/jimmunol.100 3032
    • (2011) J Immunol , vol.186 , pp. 1840-1848
    • De Weers, M.1    Tai, Y.T.2    Van Der Veer, M.S.3    Bakker, J.M.4    Vink, T.5    Jacobs, D.C.6    Oomen, L.A.7    Peipp, M.8    Valerius, T.9    Slootstra, J.W.10
  • 58
    • 51649123832 scopus 로고    scopus 로고
    • Lymphoma depletion during CD20 immunotherapy in mice is mediated by macrophage FcgammaRI, FcgammaRIII, and FcgammaRIV
    • PMID:18495955
    • Minard-Colin V, Xiu Y, Poe JC, Horikawa M, Magro CM, Hamaguchi Y, Haas KM, Tedder TF. Lymphoma depletion during CD20 immunotherapy in mice is mediated by macrophage FcgammaRI, FcgammaRIII, and FcgammaRIV. Blood 2008; 112:1205-13; PMID:18495955; http://dx.doi.org/10.1182/ blood-2008-01-135160
    • (2008) Blood , vol.112 , pp. 1205-1213
    • Minard-Colin, V.1    Xiu, Y.2    Poe, J.C.3    Horikawa, M.4    Magro, C.M.5    Hamaguchi, Y.6    Haas, K.M.7    Tedder, T.F.8
  • 59
    • 3042592452 scopus 로고    scopus 로고
    • The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy
    • PMID:15210744
    • Uchida J, Hamaguchi Y, Oliver JA, Ravetch JV, Poe JC, Haas KM, Tedder TF. The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy. J Exp Med 2004; 199:1659-69; PMID:15210744; http://dx.doi.org/ 10.1084/jem.20040119
    • (2004) J Exp Med , vol.199 , pp. 1659-1669
    • Uchida, J.1    Hamaguchi, Y.2    Oliver, J.A.3    Ravetch, J.V.4    Poe, J.C.5    Haas, K.M.6    Tedder, T.F.7
  • 60
    • 58149162030 scopus 로고    scopus 로고
    • Type II (tositumomab) anti-CD20 monoclonal antibody out performs type I (rituximablike) reagents in B-cell depletion regardless of complement activation
    • PMID:18583569
    • Beers SA, Chan CH, James S, French RR, Attfield KE, Brennan CM, Ahuja A, Shlomchik MJ, Cragg MS, Glennie MJ. Type II (tositumomab) anti-CD20 monoclonal antibody out performs type I (rituximablike) reagents in B-cell depletion regardless of complement activation. Blood 2008; 112:4170-7; PMID:18583569; http://dx.doi.org/10.1182/blood-2008-04-149161
    • (2008) Blood , vol.112 , pp. 4170-4177
    • Beers, S.A.1    Chan, C.H.2    James, S.3    French, R.R.4    Attfield, K.E.5    Brennan, C.M.6    Ahuja, A.7    Shlomchik, M.J.8    Cragg, M.S.9    Glennie, M.J.10
  • 61
    • 77954679392 scopus 로고    scopus 로고
    • Antigenic modulation limits the efficacy of anti-CD20 antibodies: Implications for antibody selection
    • PMID:202239 20
    • Beers SA, French RR, Chan HT, Lim SH, Jarrett TC, Vidal RM, Wijayaweera SS, Dixon SV, Kim H, Cox KL, et al. Antigenic modulation limits the efficacy of anti-CD20 antibodies: implications for antibody selection. Blood 2010; 115:5191-201; PMID:202239 20; http://dx.doi.org/10.1182/blood-2010-01-2635 33
    • (2010) Blood , vol.115 , pp. 5191-5201
    • Beers, S.A.1    French, R.R.2    Chan, H.T.3    Lim, S.H.4    Jarrett, T.C.5    Vidal, R.M.6    Wijayaweera, S.S.7    Dixon, S.V.8    Kim, H.9    Cox, K.L.10
  • 62
    • 69949120991 scopus 로고    scopus 로고
    • Investigation of the mechanism of action of alemtuzumab in a human CD52 transgenic mouse model
    • PMID:19740383
    • Hu Y, Turner MJ, Shields J, Gale MS, Hutto E, Roberts BL, Siders WM, Kaplan JM. Investigation of the mechanism of action of alemtuzumab in a human CD52 transgenic mouse model. Immunology 2009; 128:260-70; PMID:19740383; http://dx.doi.org/ 10.1111/j.1365-2567.2009.03115.x
    • (2009) Immunology , vol.128 , pp. 260-270
    • Hu, Y.1    Turner, M.J.2    Shields, J.3    Gale, M.S.4    Hutto, E.5    Roberts, B.L.6    Siders, W.M.7    Kaplan, J.M.8
  • 63
    • 58149198794 scopus 로고    scopus 로고
    • Experimental antibody therapy of liver metastases reveals functional redundancy between Fc gammaRI and Fc gammaRIV
    • PMID:18981101
    • Otten MA, van der Bij GJ, Verbeek SJ, Nimmerjahn F, Ravetch JV, Beelen RH, van de Winkel JG, van Egmond M. Experimental antibody therapy of liver metastases reveals functional redundancy between Fc gammaRI and Fc gammaRIV. J Immunol 2008; 181:6829-36; PMID:18981101; http://dx.doi.org/ 10.4049/jimmunol.181.10.6829
    • (2008) J Immunol , vol.181 , pp. 6829-6836
    • Otten, M.A.1    Van Der Bij, G.J.2    Verbeek, S.J.3    Nimmerjahn, F.4    Ravetch, J.V.5    Beelen, R.H.6    Van De Winkel, J.G.7    Van Egmond, M.8
  • 64
  • 65
    • 1642306050 scopus 로고    scopus 로고
    • Antibody specificity controls in vivo effector mechanisms of anti-CD20 reagents
    • PMID:14551143
    • Cragg MS, Glennie MJ. Antibody specificity controls in vivo effector mechanisms of anti-CD20 reagents. Blood 2004; 103:2738-43; PMID:14551143; http:// dx.doi.org/10.1182/blood-2003-06-2031
    • (2004) Blood , vol.103 , pp. 2738-2743
    • Cragg, M.S.1    Glennie, M.J.2
  • 66
    • 28544440831 scopus 로고    scopus 로고
    • Complement-mediated mechanisms in anti-GD2 monoclonal antibody therapy of murine metastatic cancer
    • PMID: 16288049
    • Imai M, Landen C, Ohta R, Cheung NK, Tomlinson S. Complement-mediated mechanisms in anti-GD2 monoclonal antibody therapy of murine metastatic cancer. Cancer Res 2005; 65:10562-8; PMID: 16288049; http://dx.doi.org/10.1158/0008-5472. CAN-05-1894
    • (2005) Cancer Res , vol.65 , pp. 10562-10568
    • Imai, M.1    Landen, C.2    Ohta, R.3    Cheung, N.K.4    Tomlinson, S.5
  • 68
    • 0037306990 scopus 로고    scopus 로고
    • An anti-C3b(i) mAb enhances complement activation, C3b(i) deposition, and killing of CD20C cells by rituximab
    • PMID:12393727
    • Kennedy AD, Solga MD, Schuman TA, Chi AW, Lindorfer MA, Sutherland WM, Foley PL, Taylor RP. An anti-C3b(i) mAb enhances complement activation, C3b(i) deposition, and killing of CD20C cells by rituximab. Blood 2003; 101:1071-9; PMID:12393727; http://dx.doi.org/10.1182/blood-2002-03-0876
    • (2003) Blood , vol.101 , pp. 1071-1079
    • Kennedy, A.D.1    Solga, M.D.2    Schuman, T.A.3    Chi, A.W.4    Lindorfer, M.A.5    Sutherland, W.M.6    Foley, P.L.7    Taylor, R.P.8
  • 70
    • 70049114231 scopus 로고    scopus 로고
    • Enhancing the action of rituximab in chronic lymphocytic leukemia by adding fresh frozen plasma: Complement/rituximab interactions & clinical results in refractory CLL
    • PMID:19758239
    • Klepfish A, Gilles L, Ioannis K, Rachmilewitz EA, Schattner A. Enhancing the action of rituximab in chronic lymphocytic leukemia by adding fresh frozen plasma: complement/rituximab interactions & clinical results in refractory CLL. Ann N Y Acad Sci 2009; 1173:865-73; PMID:19758239; http://dx.doi.org/ 10.1111/j.1749-6632.2009.04803.x
    • (2009) Ann N Y Acad Sci , vol.1173 , pp. 865-873
    • Klepfish, A.1    Gilles, L.2    Ioannis, K.3    Rachmilewitz, E.A.4    Schattner, A.5
  • 71
    • 79952462585 scopus 로고    scopus 로고
    • Enhancing the action of rituximab by adding fresh frozen plasma for the treatment of fludarabine refractory chronic lymphocytic leukemia
    • PMID:20635386
    • Xu W, Miao KR, Zhu DX, Fang C, Zhu HY, Dong HJ, Wang DM, Wu YJ, Qiao C, Li JY. Enhancing the action of rituximab by adding fresh frozen plasma for the treatment of fludarabine refractory chronic lymphocytic leukemia. Int J Cancer 2011; 128:2192-201; PMID:20635386; http://dx.doi.org/10.1002/ ijc.25560
    • (2011) Int J Cancer , vol.128 , pp. 2192-2201
    • Xu, W.1    Miao, K.R.2    Zhu, D.X.3    Fang, C.4    Zhu, H.Y.5    Dong, H.J.6    Wang, D.M.7    Wu, Y.J.8    Qiao, C.9    Li, J.Y.10
  • 72
    • 38949121647 scopus 로고    scopus 로고
    • NK-cell activation and antibody-dependent cellular cytotoxicity induced by rituximab-coated target cells is inhibited by the C3b component of complement
    • PMID:18024795
    • Wang SY, Racila E, Taylor RP, Weiner GJ. NK-cell activation and antibody-dependent cellular cytotoxicity induced by rituximab-coated target cells is inhibited by the C3b component of complement. Blood 2008; 111:1456-63; PMID:18024795; http://dx.doi. org/10.1182/blood-2007-02-074716
    • (2008) Blood , vol.111 , pp. 1456-1463
    • Wang, S.Y.1    Racila, E.2    Taylor, R.P.3    Weiner, G.J.4
  • 73
    • 84883264834 scopus 로고    scopus 로고
    • GA101 induces NK-cell activation and antibody-dependent cellular cytotoxicity more effectively than rituximab when complement is present
    • PMID: 23452151
    • Kern DJ, James BR, Blackwell S, Gassner C, Klein C, Weiner GJ. GA101 induces NK-cell activation and antibody-dependent cellular cytotoxicity more effectively than rituximab when complement is present. Leuk Lymphoma 2013; 54:2500-5; PMID: 23452151; http://dx.doi.org/10.3109/10428194. 2013.781169
    • (2013) Leuk Lymphoma , vol.54 , pp. 2500-2505
    • Kern, D.J.1    James, B.R.2    Blackwell, S.3    Gassner, C.4    Klein, C.5    Weiner, G.J.6
  • 74
    • 73949123455 scopus 로고    scopus 로고
    • Depletion of the C3 component of complement enhances the ability of rituximab-coated target cells to activate human NK cells and improves the efficacy of monoclonal antibody therapy in an in vivo model
    • PMID:19805620
    • Wang SY, Veeramani S, Racila E, Cagley J, Fritzinger DC, Vogel CW, St John W, Weiner GJ. Depletion of the C3 component of complement enhances the ability of rituximab-coated target cells to activate human NK cells and improves the efficacy of monoclonal antibody therapy in an in vivo model. Blood 2009; 114:5322-30; PMID:19805620; http://dx.doi.org/ 10.1182/blood-2009-01-200469
    • (2009) Blood , vol.114 , pp. 5322-5330
    • Wang, S.Y.1    Veeramani, S.2    Racila, E.3    Cagley, J.4    Fritzinger, D.C.5    Vogel, C.W.6    St John, W.7    Weiner, G.J.8
  • 75
    • 58149176733 scopus 로고    scopus 로고
    • A polymorphism in the complement component C1qA correlates with prolonged response following rituximab therapy of follicular lymphoma
    • PMID:18927313
    • Racila E, Link BK, Weng WK, Witzig TE, Ansell S, Maurer MJ, Huang J, Dahle C, Halwani A, Levy R, et al. A polymorphism in the complement component C1qA correlates with prolonged response following rituximab therapy of follicular lymphoma. Clin Cancer Res 2008; 14:6697-703; PMID:18927313; http:// dx.doi.org/10.1158/1078-0432.CCR-08-0745
    • (2008) Clin Cancer Res , vol.14 , pp. 6697-6703
    • Racila, E.1    Link, B.K.2    Weng, W.K.3    Witzig, T.E.4    Ansell, S.5    Maurer, M.J.6    Huang, J.7    Dahle, C.8    Halwani, A.9    Levy, R.10
  • 77
    • 84873407750 scopus 로고    scopus 로고
    • Transient removal of CD46 is safe and increases B-cell depletion by rituximab in CD46 transgenic mice and macaques
    • PMID: 23089733
    • Beyer I, Cao H, Persson J, Wang H, Liu Y, Yumul R, Li Z, Woodle D, Manger R, Gough M, et al. Transient removal of CD46 is safe and increases B-cell depletion by rituximab in CD46 transgenic mice and macaques. Mol Ther 2013; 21:291-9; PMID: 23089733; http://dx.doi.org/10.1038/mt.2012.212
    • (2013) Mol Ther , vol.21 , pp. 291-299
    • Beyer, I.1    Cao, H.2    Persson, J.3    Wang, H.4    Liu, Y.5    Yumul, R.6    Li, Z.7    Woodle, D.8    Manger, R.9    Gough, M.10
  • 78
    • 0032159271 scopus 로고    scopus 로고
    • Cytokines modulate expression of cell-membrane complement inhibitory proteins in human lung cancer cell lines
    • PMID:9730881
    • Varsano S, Rashkovsky L, Shapiro H, Radnay J. Cytokines modulate expression of cell-membrane complement inhibitory proteins in human lung cancer cell lines. Am J Respir Cell Mol Biol 1998; 19:522-9; PMID:9730881; http://dx.doi.org/10.1165/ajrcmb. 19.3.3181
    • (1998) Am J Respir Cell Mol Biol , vol.19 , pp. 522-529
    • Varsano, S.1    Rashkovsky, L.2    Shapiro, H.3    Radnay, J.4
  • 79
    • 0038717063 scopus 로고    scopus 로고
    • Cytokines affect resistance of human renal tumour cells to complement-mediated injury
    • PMID:12791098
    • Blok VT, Gelderman KA, Tijsma OH, Daha MR, Gorter A. Cytokines affect resistance of human renal tumour cells to complement-mediated injury. Scand J Immunol 2003; 57:591-9; PMID:12791098; http:// dx.doi.org/10.1046/j.1365-3083.2003.01265.x
    • (2003) Scand J Immunol , vol.57 , pp. 591-599
    • Blok, V.T.1    Gelderman, K.A.2    Tijsma, O.H.3    Daha, M.R.4    Gorter, A.5
  • 80
    • 84862833647 scopus 로고    scopus 로고
    • Inhibition of membrane complement inhibitor expression (CD46, CD55, CD59) by siRNA sensitizes tumor cells to complement attack in vitro
    • PMID:20879979
    • Geis N, Zell S, Rutz R, Li W, Giese T, Mamidi S, Schultz S, Kirschfink M. Inhibition of membrane complement inhibitor expression (CD46, CD55, CD59) by siRNA sensitizes tumor cells to complement attack in vitro. Curr Cancer Drug Targets 2010; 10:922-31; PMID:20879979; http://dx.doi.org/ 10.2174/156800910793357952
    • (2010) Curr Cancer Drug Targets , vol.10 , pp. 922-931
    • Geis, N.1    Zell, S.2    Rutz, R.3    Li, W.4    Giese, T.5    Mamidi, S.6    Schultz, S.7    Kirschfink, M.8
  • 81
    • 32944455120 scopus 로고    scopus 로고
    • Blockade of bulky lymphomaassociated CD55 expression by RNA interference overcomes resistance to complement-dependent cytotoxicity with rituximab
    • PMID:16367924
    • Terui Y, Sakurai T, Mishima Y, Mishima Y, Sugimura N, Sasaoka C, Kojima K, Yokoyama M, Mizunuma N, Takahashi S, et al. Blockade of bulky lymphomaassociated CD55 expression by RNA interference overcomes resistance to complement-dependent cytotoxicity with rituximab. Cancer Sci 2006; 97:72-9; PMID:16367924; http://dx.doi.org/10.1111/j.1349-7006.2006.00139.x
    • (2006) Cancer Sci , vol.97 , pp. 72-79
    • Terui, Y.1    Sakurai, T.2    Mishima, Y.3    Mishima, Y.4    Sugimura, N.5    Sasaoka, C.6    Kojima, K.7    Yokoyama, M.8    Mizunuma, N.9    Takahashi, S.10
  • 82
    • 84878107502 scopus 로고    scopus 로고
    • Lipoplex mediated silencing of membrane regulators (CD46, CD55 and CD59) enhances com-plement-dependent anti-tumor activity of trastuzumab and pertuzumab
    • PMID:23474221
    • Mamidi S, Cinci M, Hasmann M, Fehring V, Kirschfink M. Lipoplex mediated silencing of membrane regulators (CD46, CD55 and CD59) enhances com-plement-dependent anti-tumor activity of trastuzumab and pertuzumab. Mol Oncol 2013; 7:580-94; PMID:23474221; http://dx.doi.org/10.1016/j. molonc.2013.02.011
    • (2013) Mol Oncol , vol.7 , pp. 580-594
    • Mamidi, S.1    Cinci, M.2    Hasmann, M.3    Fehring, V.4    Kirschfink, M.5
  • 83
    • 79952759542 scopus 로고    scopus 로고
    • Human CD59 inhibitor sensitizes rituximab-resistant lymphoma cells to complement-mediated cytolysis
    • PMID:21252115
    • Hu W, Ge X, You T, Xu T, Zhang J, Wu G, Peng Z, Chorev M, Aktas BH, Halperin JA, et al. Human CD59 inhibitor sensitizes rituximab-resistant lymphoma cells to complement-mediated cytolysis. Cancer Res 2011; 71:2298-307; PMID:21252115; http:// dx.doi.org/10.1158/0008-5472.CAN-10-3016
    • (2011) Cancer Res , vol.71 , pp. 2298-2307
    • Hu, W.1    Ge, X.2    You, T.3    Xu, T.4    Zhang, J.5    Wu, G.6    Peng, Z.7    Chorev, M.8    Aktas, B.H.9    Halperin, J.A.10
  • 84
    • 80455162357 scopus 로고    scopus 로고
    • RILYd4, a human CD59 inhibitor, enhances complement-dependent cytotoxicity of ofatumumab against rituximab-resistant B-cell lymphoma cells and chronic lymphocytic leukemia
    • PMID:21918174
    • Ge X, Wu L, Hu W, Fernandes S, Wang C, Li X, Brown JR, Qin X. rILYd4, a human CD59 inhibitor, enhances complement-dependent cytotoxicity of ofatumumab against rituximab-resistant B-cell lymphoma cells and chronic lymphocytic leukemia. Clin Cancer Res 2011; 17:6702-11; PMID:21918174; http://dx.doi.org/10.1158/1078-0432.CCR-11-0647
    • (2011) Clin Cancer Res , vol.17 , pp. 6702-6711
    • Ge, X.1    Wu, L.2    Hu, W.3    Fernandes, S.4    Wang, C.5    Li, X.6    Brown, J.R.7    Qin, X.8
  • 85
    • 0034660092 scopus 로고    scopus 로고
    • Biologic response of B lymphoma cells to anti-CD20 monoclonal antibody rituximab in vitro: CD55 and CD59 regulate complement-mediated cell lysis
    • PMID:10845926
    • Golay J, Zaffaroni L, Vaccari T, Lazzari M, Borleri GM, Bernasconi S, Tedesco F, Rambaldi A, Introna M. Biologic response of B lymphoma cells to anti-CD20 monoclonal antibody rituximab in vitro: CD55 and CD59 regulate complement-mediated cell lysis. Blood 2000; 95:3900-8; PMID:10845926
    • (2000) Blood , vol.95 , pp. 3900-3908
    • Golay, J.1    Zaffaroni, L.2    Vaccari, T.3    Lazzari, M.4    Borleri, G.M.5    Bernasconi, S.6    Tedesco, F.7    Rambaldi, A.8    Introna, M.9
  • 86
    • 22544462219 scopus 로고    scopus 로고
    • Controlling complement resistance in cancer by using human monoclonal antibodies that neutralize complement-regulatory proteins CD55 and CD59
    • PMID: 15971270
    • Ziller F, Macor P, Bulla R, Sblattero D, Marzari R, Tedesco F. Controlling complement resistance in cancer by using human monoclonal antibodies that neutralize complement-regulatory proteins CD55 and CD59. Eur J Immunol 2005; 35:2175-83; PMID: 15971270; http://dx.doi.org/10.1002/eji.200425920
    • (2005) Eur J Immunol , vol.35 , pp. 2175-2183
    • Ziller, F.1    Macor, P.2    Bulla, R.3    Sblattero, D.4    Marzari, R.5    Tedesco, F.6
  • 87
    • 35948989248 scopus 로고    scopus 로고
    • In vivo targeting of human neutralizing antibodies against CD55 and CD59 to lymphoma cells increases the antitumor activity of rituximab
    • PMID:17975000
    • Macor P, Tripodo C, Zorzet S, Piovan E, Bossi F, Marzari R, Amadori A, Tedesco F. In vivo targeting of human neutralizing antibodies against CD55 and CD59 to lymphoma cells increases the antitumor activity of rituximab. Cancer Res 2007; 67:10556-63; PMID:17975000; http://dx.doi.org/10.1158/0008-5472.CAN-07-1811
    • (2007) Cancer Res , vol.67 , pp. 10556-10563
    • Macor, P.1    Tripodo, C.2    Zorzet, S.3    Piovan, E.4    Bossi, F.5    Marzari, R.6    Amadori, A.7    Tedesco, F.8
  • 88
    • 0036226284 scopus 로고    scopus 로고
    • The inhibitory effect of CD46, CD55, and CD59 on complement activation after immunotherapeutic treatment of cervical carcinoma cells with monoclonal antibodies or bispecific monoclonal antibodies
    • PMID:11950905
    • Gelderman KA, Blok VT, Fleuren GJ, Gorter A. The inhibitory effect of CD46, CD55, and CD59 on complement activation after immunotherapeutic treatment of cervical carcinoma cells with monoclonal antibodies or bispecific monoclonal antibodies. Lab Invest 2002; 82:483-93; PMID:11950905; http://dx. doi.org/10.1038/labinvest.3780441
    • (2002) Lab Invest , vol.82 , pp. 483-493
    • Gelderman, K.A.1    Blok, V.T.2    Fleuren, G.J.3    Gorter, A.4
  • 89
    • 0036147901 scopus 로고    scopus 로고
    • Enhancement of the complement activating capacity of 17-1A mAb to overcome the effect of membrane-bound complement regulatory proteins on colorectal carcinoma
    • PMID:11754353
    • Gelderman KA, Kuppen PJ, Bruin W, Fleuren GJ, Gorter A. Enhancement of the complement activating capacity of 17-1A mAb to overcome the effect of membrane-bound complement regulatory proteins on colorectal carcinoma. Eur J Immunol 2002; 32:128-35; PMID:11754353; http://dx.doi.org/10.1002/ 1521-4141(200201)32:1< 128::AID-IMMU128>3. 0.CO;2-P
    • (2002) Eur J Immunol , vol.32 , pp. 128-135
    • Gelderman, K.A.1    Kuppen, P.J.2    Bruin, W.3    Fleuren, G.J.4    Gorter, A.5
  • 90
    • 3042615969 scopus 로고    scopus 로고
    • Tumor-specific inhibition of membranebound complement regulatory protein Crry with bispecific monoclonal antibodies prevents tumor outgrowth in a rat colorectal cancer lung metastases model
    • PMID: 15205353
    • Gelderman KA, Kuppen PJ, Okada N, Fleuren GJ, Gorter A. Tumor-specific inhibition of membranebound complement regulatory protein Crry with bispecific monoclonal antibodies prevents tumor outgrowth in a rat colorectal cancer lung metastases model. Cancer Res 2004; 64:4366-72; PMID: 15205353; http://dx.doi.org/10.1158/0008-5472. CAN-03-2131
    • (2004) Cancer Res , vol.64 , pp. 4366-4372
    • Gelderman, K.A.1    Kuppen, P.J.2    Okada, N.3    Fleuren, G.J.4    Gorter, A.5
  • 91
    • 84889808921 scopus 로고    scopus 로고
    • Complement factor H-derived short consensus repeat 18-20 enhanced complement-dependent cytotoxicity of ofatumumab on chronic lymphocytic leukemia cells
    • PMID:23850806
    • Horl S, Banki Z, Huber G, Ejaz A, Mullauer B, Willenbacher E, Steurer M, Stoiber H. Complement factor H-derived short consensus repeat 18-20 enhanced complement-dependent cytotoxicity of ofatumumab on chronic lymphocytic leukemia cells. Haematologica 2013; 98:1939-47; PMID:23850806; http://dx. doi.org/10.3324/haematol.2013.089615
    • (2013) Haematologica , vol.98 , pp. 1939-1947
    • Horl, S.1    Banki, Z.2    Huber, G.3    Ejaz, A.4    Mullauer, B.5    Willenbacher, E.6    Steurer, M.7    Stoiber, H.8
  • 92
    • 84887321596 scopus 로고    scopus 로고
    • Reduction of complement factor H binding to CLL cells improves the induction of rituximab-mediated complement-dependent cytotoxicity
    • PMID:23760402
    • Horl S, B-anki Z, Huber G, Ejaz A, Windisch D, Muellauer B, Willenbacher E, Steurer M, Stoiber H. Reduction of complement factor H binding to CLL cells improves the induction of rituximab-mediated complement-dependent cytotoxicity. Leukemia 2013; 27:2200-8; PMID:23760402; http://dx.doi.org/ 10.1038/leu.2013.169
    • (2013) Leukemia , vol.27 , pp. 2200-2208
    • Horl, S.1    B-anki, Z.2    Huber, G.3    Ejaz, A.4    Windisch, D.5    Muellauer, B.6    Willenbacher, E.7    Steurer, M.8    Stoiber, H.9
  • 93
    • 84913587067 scopus 로고    scopus 로고
    • CD20 mAb-Mediated Complement Dependent Cytotoxicity of Tumor Cells is Enhanced by Blocking the Action of Factor I
    • Lindorfer MA, Beum PV, Taylor RP. CD20 mAb-Mediated Complement Dependent Cytotoxicity of Tumor Cells is Enhanced by Blocking the Action of Factor I. Antibodies 2013; 2:598-616; http://dx.doi. org/10.3390/antib2040598
    • (2013) Antibodies , vol.2 , pp. 598-616
    • Lindorfer, M.A.1    Beum, P.V.2    Taylor, R.P.3
  • 94
    • 0035094143 scopus 로고    scopus 로고
    • Membrane complement regulatory proteins: Insight from animal studies and relevance to human diseases
    • PMID:11367529
    • Miwa T, Song WC. Membrane complement regulatory proteins: insight from animal studies and relevance to human diseases. Int Immunopharmacol 2001; 1:445-59; PMID:11367529; http://dx.doi.org/ 10.1016/S1567-5769(00)00043-6
    • (2001) Int Immunopharmacol , vol.1 , pp. 445-459
    • Miwa, T.1    Song, W.C.2
  • 95
    • 0024787408 scopus 로고
    • Mouse strains with typical mammalian levels of complement activity
    • PMID:2607149
    • Ong GL, Mattes MJ. Mouse strains with typical mammalian levels of complement activity. J Immunol Methods 1989; 125:147-58; PMID:2607149; http:// dx.doi.org/10.1016/0022-1759(89)90088-4
    • (1989) J Immunol Methods , vol.125 , pp. 147-158
    • Ong, G.L.1    Mattes, M.J.2
  • 96
    • 71749090992 scopus 로고    scopus 로고
    • High throughput screening for antibody induced complement-dependent cytotoxicity in early antibody discovery using homogeneous macroconfocal fluorescence imaging
    • PMID:19891971
    • Gerritsen AF, Bosch M, de Weers M, de Winkel JG, Parren PW. High throughput screening for antibody induced complement-dependent cytotoxicity in early antibody discovery using homogeneous macroconfocal fluorescence imaging. J Immunol Methods 2010; 352:140-6; PMID:19891971; http://dx.doi.org/ 10.1016/j.jim.2009.10.009
    • (2010) J Immunol Methods , vol.352 , pp. 140-146
    • Gerritsen, A.F.1    Bosch, M.2    De Weers, M.3    De Winkel, J.G.4    Parren, P.W.5
  • 97
    • 84875805834 scopus 로고    scopus 로고
    • An IgG3 switch variant of rituximab mediates enhanced complementdependent cytotoxicity against tumour cells with low CD20 expression levels
    • PMID:23294176
    • Rosner T, Derer S, Kellner C, Dechant M, Lohse S, Vidarsson G, Peipp M, Valerius T. An IgG3 switch variant of rituximab mediates enhanced complementdependent cytotoxicity against tumour cells with low CD20 expression levels. Br J Haematol 2013; 161:282-6; PMID:23294176; http://dx.doi.org/ 10.1111/bjh.12209
    • (2013) Br J Haematol , vol.161 , pp. 282-286
    • Rosner, T.1    Derer, S.2    Kellner, C.3    Dechant, M.4    Lohse, S.5    Vidarsson, G.6    Peipp, M.7    Valerius, T.8
  • 100
    • 0034983614 scopus 로고    scopus 로고
    • Lysine 322 in the human IgG3 C(H)2 domain is crucial for antibody dependent complement activation
    • PMID:11395138
    • Thommesen JE, Michaelsen TE, Løset GA, Sandlie I, Brekke OH. Lysine 322 in the human IgG3 C(H)2 domain is crucial for antibody dependent complement activation. Mol Immunol 2000; 37:995-1004; PMID:11395138; http://dx.doi.org/10.1016/S0161-5890(01)00010-4
    • (2000) Mol Immunol , vol.37 , pp. 995-1004
    • Thommesen, J.E.1    Michaelsen, T.E.2    Løset, G.A.3    Sandlie, I.4    Brekke, O.H.5
  • 102
    • 77953659426 scopus 로고    scopus 로고
    • Engineered Fc variant antibodies with enhanced ability to recruit complement and mediate effector functions
    • PMID:20150767
    • Moore GL, Chen H, Karki S, Lazar GA. Engineered Fc variant antibodies with enhanced ability to recruit complement and mediate effector functions. MAbs 2010; 2:181-9; PMID:20150767; http://dx.doi.org/ 10.4161/mabs.2.2.11158
    • (2010) MAbs , vol.2 , pp. 181-189
    • Moore, G.L.1    Chen, H.2    Karki, S.3    Lazar, G.A.4
  • 103
    • 0036284422 scopus 로고    scopus 로고
    • Targeting multiple Her-2 epitopes with monoclonal antibodies results in improved antigrowth activity of a human breast cancer cell line in vitro and in vivo
    • PMID:12060609
    • Spiridon CI, Ghetie MA, Uhr J, Marches R, Li JL, Shen GL, Vitetta ES. Targeting multiple Her-2 epitopes with monoclonal antibodies results in improved antigrowth activity of a human breast cancer cell line in vitro and in vivo. Clin Cancer Res 2002; 8:1720-30; PMID:12060609
    • (2002) Clin Cancer Res , vol.8 , pp. 1720-1730
    • Spiridon, C.I.1    Ghetie, M.A.2    Uhr, J.3    Marches, R.4    Li, J.L.5    Shen, G.L.6    Vitetta, E.S.7
  • 107
    • 0029558207 scopus 로고
    • The effect of the removal of sialic acid, galactose and total carbohydrate on the functional activity of Campath-1H
    • PMID:8643100
    • Boyd PN, Lines AC, Patel AK. The effect of the removal of sialic acid, galactose and total carbohydrate on the functional activity of Campath-1H. Mol Immunol 1995; 32:1311-8; PMID:8643100; http:// dx.doi.org/10.1016/0161-5890(95)00118-2
    • (1995) Mol Immunol , vol.32 , pp. 1311-1318
    • Boyd, P.N.1    Lines, A.C.2    Patel, A.K.3
  • 109
    • 0028962403 scopus 로고
    • Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein
    • PMID:7585040
    • Malhotra R, Wormald MR, Rudd PM, Fischer PB, Dwek RA, Sim RB. Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein. Nat Med 1995; 1:237-43; PMID:7585040; http://dx.doi.org/ 10.1038/nm0395-237
    • (1995) Nat Med , vol.1 , pp. 237-243
    • Malhotra, R.1    Wormald, M.R.2    Rudd, P.M.3    Fischer, P.B.4    Dwek, R.A.5    Sim, R.B.6
  • 110
    • 0032055988 scopus 로고    scopus 로고
    • Effect of C2-associated carbohydrate structure on Ig effector function: Studies with chimeric mouse-human IgG1 antibodies in glycosylation mutants of Chinese hamster ovary cells
    • PMID:9531299
    • Wright A, Morrison SL. Effect of C2-associated carbohydrate structure on Ig effector function: studies with chimeric mouse-human IgG1 antibodies in glycosylation mutants of Chinese hamster ovary cells. J Immunol 1998; 160:3393-402; PMID:9531299
    • (1998) J Immunol , vol.160 , pp. 3393-3402
    • Wright, A.1    Morrison, S.L.2
  • 111
    • 0037178791 scopus 로고    scopus 로고
    • Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibodydependent cellular toxicity
    • PMID:11986321
    • Shields RL, Lai J, Keck R, O'Connell LY, Hong K, Meng YG, Weikert SH, Presta LG. Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibodydependent cellular toxicity. J Biol Chem 2002; 277:26733-40; PMID:11986321; http://dx.doi.org/ 10.1074/jbc.M202069200
    • (2002) J Biol Chem , vol.277 , pp. 26733-26740
    • Shields, R.L.1    Lai, J.2    Keck, R.3    O'Connell, L.Y.4    Hong, K.5    Meng, Y.G.6    Weikert, S.H.7    Presta, L.G.8
  • 112
    • 34347235526 scopus 로고    scopus 로고
    • Agalactosylated IgG antibodies depend on cellular Fc receptors for in vivo activity
    • PMID:17485663
    • Nimmerjahn F, Anthony RM, Ravetch JV. Agalactosylated IgG antibodies depend on cellular Fc receptors for in vivo activity. Proc Natl Acad Sci U S A 2007; 104:8433-7; PMID:17485663; http://dx.doi.org/ 10.1073/pnas.0702936104
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 8433-8437
    • Nimmerjahn, F.1    Anthony, R.M.2    Ravetch, J.V.3
  • 113
    • 0024505643 scopus 로고
    • Targeting of complement to tumor cells by heteroconjugates composed of antibodies and of the complement component C3b
    • PMID:2522969
    • Reiter Y, Fishelson Z. Targeting of complement to tumor cells by heteroconjugates composed of antibodies and of the complement component C3b. J Immunol 1989; 142:2771-7; PMID:2522969
    • (1989) J Immunol , vol.142 , pp. 2771-2777
    • Reiter, Y.1    Fishelson, Z.2
  • 114
    • 0025133258 scopus 로고
    • Complement killing of human neuroblastoma cells: A cytotoxic monoclonal antibody and its F (ab')2-cobra venom factor conjugate are equally cytotoxic
    • PMID: 2233757
    • Juhl H, Petrella EC, Cheung NK, Bredehorst R, Vogel CW. Complement killing of human neuroblastoma cells: a cytotoxic monoclonal antibody and its F (ab')2-cobra venom factor conjugate are equally cytotoxic. Mol Immunol 1990; 27:957-64; PMID: 2233757; http://dx.doi.org/10.1016/0161-5890(90) 90118-J
    • (1990) Mol Immunol , vol.27 , pp. 957-964
    • Juhl, H.1    Petrella, E.C.2    Cheung, N.K.3    Bredehorst, R.4    Vogel, C.W.5
  • 115
    • 0030716387 scopus 로고    scopus 로고
    • Additive cytotoxicity of different monoclonal antibody-cobra venom factor conjugates for human neuroblastoma cells
    • PMID:9413745
    • Juhl H, Petrella EC, Cheung NK, Bredehorst R, Vogel CW. Additive cytotoxicity of different monoclonal antibody-cobra venom factor conjugates for human neuroblastoma cells. Immunobiology 1997; 197:444-59; PMID:9413745; http://dx.doi.org/ 10.1016/S0171-2985(97)80078-2
    • (1997) Immunobiology , vol.197 , pp. 444-459
    • Juhl, H.1    Petrella, E.C.2    Cheung, N.K.3    Bredehorst, R.4    Vogel, C.W.5
  • 116
    • 84866701494 scopus 로고    scopus 로고
    • Anti-tumor monoclonal antibodies in conjunction with b-glucans: A novel anti-cancer immunotherapy
    • PMID:22834812
    • Xiang D, Sharma VR, Freter CE, Yan J. Anti-tumor monoclonal antibodies in conjunction with b-glucans: a novel anti-cancer immunotherapy. Curr Med Chem 2012; 19:4298-305; PMID:22834812; http://dx.doi. org/10.2174/092986712802884303
    • (2012) Curr Med Chem , vol.19 , pp. 4298-4305
    • Xiang, D.1    Sharma, V.R.2    Freter, C.E.3    Yan, J.4
  • 117
    • 35148828111 scopus 로고    scopus 로고
    • Enhancement of antibody-dependent mechanisms of tumor cell lysis by a targeted activator of complement
    • PMID:17909064
    • Imai M, Ohta R, Varela JC, Song H, Tomlinson S. Enhancement of antibody-dependent mechanisms of tumor cell lysis by a targeted activator of complement. Cancer Res 2007; 67:9535-41; PMID:17909064; http://dx.doi.org/10.1158/0008-5472.CAN-07-1690
    • (2007) Cancer Res , vol.67 , pp. 9535-9541
    • Imai, M.1    Ohta, R.2    Varela, J.C.3    Song, H.4    Tomlinson, S.5
  • 118
    • 84862733696 scopus 로고    scopus 로고
    • A targeted complement-dependent strategy to improve the outcome of mAb therapy, and characterization in a murine model of metastatic cancer
    • PMID:22442351
    • Elvington M, Huang Y, Morgan BP, Qiao F, van Rooijen N, Atkinson C, Tomlinson S. A targeted complement-dependent strategy to improve the outcome of mAb therapy, and characterization in a murine model of metastatic cancer. Blood 2012; 119:6043-51; PMID:22442351; http://dx.doi.org/ 10.1182/blood-2011-10-383232
    • (2012) Blood , vol.119 , pp. 6043-6051
    • Elvington, M.1    Huang, Y.2    Morgan, B.P.3    Qiao, F.4    Van Rooijen, N.5    Atkinson, C.6    Tomlinson, S.7
  • 119
    • 84862744077 scopus 로고    scopus 로고
    • Boosting antibody therapy with complement
    • PMID: 22730521
    • Boross P, Leusen JH. Boosting antibody therapy with complement. Blood 2012; 119:5945-7; PMID: 22730521; http://dx.doi.org/10.1182/blood-2012-04-420760
    • (2012) Blood , vol.119 , pp. 5945-5947
    • Boross, P.1    Leusen, J.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.