Nitric oxide transport in normal human thoracic aorta:Effects of hemodynamics and nitric oxide scavengers

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Liu, Xiao ^a   Wang, Zhenze ^a   Zhao, Ping ^a   Fan, Zhanming ^b   Sun, Anqiang ^a   Zhan, Fan ^a   Fan, Yubo ^a   Deng, Xiaoyan ^a  

^a BEIHANG UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE; SCAVENGER;

AORTA FLOW; AORTA WALL; ARTERY ENDOTHELIUM; ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; HEMODYNAMICS; HUMAN; MALE; MATHEMATICAL MODEL; SHEAR STRESS; THORACIC AORTA; TRANSPORT KINETICS; BIOLOGICAL MODEL; METABOLISM; PHYSIOLOGY; VASCULAR ENDOTHELIUM;

AORTA, THORACIC; ENDOTHELIUM, VASCULAR; ERYTHROCYTES; FREE RADICAL SCAVENGERS; HEMODYNAMICS; HUMANS; MALE; MODELS, CARDIOVASCULAR; NITRIC OXIDE;

EID: 84913573628     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0112395     Document Type: Article

References (54)

1. Davignon J, Ganz P (2004) Role of endothelial dysfunction in atherosclerosis. Circulation 109: III27-32.
2. Lasheras JC (2007) The biomechanics of arterial aneurysms. Annual Review of Fluid Mechanics 39: 293-319.
3. Napoli C, de Nigris F, Williams-Ignarro S, Pignalosa O, Sica V, et al. (2006) Nitric oxide and atherosclerosis: an update. Nitric Oxide 15: 265-279.
4. Moncada S, Palmer RM, Higgs EA (1991) Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 43: 109-142.
5. Chen K, Pittman RN, Popel AS (2008) Nitric oxide in the vasculature: where does it come from and where does it go? A quantitative perspective. Antioxid Redox Signal 10: 1185-1198.
6. Jin RC, Loscalzo J (2010) Vascular Nitric Oxide: Formation and Function. J Blood Med 2010: 147-162.
7. Grisham MB, Jourd'Heuil D, Wink DA (1999) Nitric oxide. I. Physiological chemistry of nitric oxide and its metabolites:implications in inflammation. Am J Physiol 276: G315-321.
8. Halligan KE, Jourd'heuil FL, Jourd'heuil D (2009) Cytoglobin Is Expressed in the Vasculature and Regulates Cell Respiration and Proliferation via Nitric Oxide Dioxygenation. Journal of Biological Chemistry 284: 8539-8547.
9. Chen X, Jaron D, Barbee KA, Buerk DG (2006) The influence of radial RBC distribution, blood velocity profiles, and glycocalyx on coupled NO/O2 transport. J Appl Physiol 100: 482-492.
10. Lancaster JR, Jr. (1994) Simulation of the diffusion and reaction of endogenously produced nitric oxide. Proc Natl Acad Sci U S A 91: 8137-8141.
11. Tsoukias NM (2008) Nitric oxide bioavailability in the microcirculation: insights from mathematical models. Microcirculation 15: 813-834.
12. Fadel AA, Barbee KA, Jaron D (2009) A computational model of nitric oxide production and transport in a parallel plate flow chamber. Ann Biomed Eng 37: 943-954.
13. Plata AM, Sherwin SJ, Krams R (2010) Endothelial nitric oxide production and transport in flow chambers: The importance of convection. Ann Biomed Eng 38: 2805-2816.
14. Cooke JP (2004) Flow, NO, and atherogenesis (vol 100, pg 768, 2003)
15. Proc Natl Acad Sci U S A 101: 18262-18262 (2004).
16. Chiu JJ, Chien S (2011) Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives. Physiol Rev 91: 327-387.
17. Liu X, Pu F, Fan Y, Deng X, Li D, et al. (2009) A numerical study on the flow of blood and the transport of LDL in the human aorta: the physiological significance of the helical flow in the aortic arch. Am J Physiol Heart Circ Physiol 297: H163-170.
18. Liu X, Fan Y, Deng X (2010) Effect of spiral flow on the transport of oxygen in the aorta: a numerical study. Ann Biomed Eng 38: 917-926.
19. El Aidi H, Mani V, Weinshelbaum KB, Aguiar SH, Taniguchi H, et al. (2009) Cross-sectional, prospective study of MRI reproducibility in the assessment of plaque burden of the carotid arteries and aorta. Nat Clin Pract Cardiovasc Med 6: 219-228.
20. Liu X, Fan Y, Xu XY, Deng X (2012) Nitric oxide transport in an axisymmetric stenosis. J R Soc Interface 9: 2468-2478.
21. Cho YI, Kensey KR (1991) Effects of the non-Newtonian viscosity of blood on flows in a diseased arterial vessel. Part 1: Steady flows. Biorheology 28: 241-262.
22. Azarov I, Huang KT, Basu S, Gladwin MT, Hogg N, et al. (2005) Nitric oxide scavenging by red blood cells as a function of hematocrit and oxygenation. J Biol Chem 280: 39024-39032.
23. Liao JC, Hein TW, Vaughn MW, Huang KT, Kuo L (1999) Intravascular flow decreases erythrocyte consumption of nitric oxide. Proc Natl Acad Sci U S A 96: 8757-8761.
24. Vaughn MW, Kuo L, Liao JC (1998) Effective diffusion distance of nitric oxide in the microcirculation. Am J Physiol 274: H1705-1714.
25. Chen K, Popel AS (2006) Theoretical analysis of biochemical pathways of nitric oxide release from vascular endothelial cells. Free Radic Biol Med 41: 668-680.
26. Andrews AM, Jaron D, Buerk DG, Kirby PL, Barbee KA (2010) Direct, realtime measurement of shear stress-induced nitric oxide produced from endothelial cells in vitro. Nitric Oxide 23: 335-342.
27. Chen X, Buerk DG, Barbee KA, Kirby P, Jaron D (2011) 3D network model of NO transport in tissue. Med Biol Eng Comput 49: 633-647.
28. Liu X, Srinivasan P, Collard E, Grajdeanu P, Zweier JL, et al. (2008) Nitric oxide diffusion rate is reduced in the aortic wall. Biophys J 94: 1880-1889.
29. Vaughn MW, Kuo L, Liao JC (1998) Estimation of nitric oxide production and reaction rates in tissue by use of a mathematical model. Am J Physiol 274: H2163-2176.
30. Gallo D, De Santis G, Negri F, Tresoldi D, Ponzini R, et al. (2012) On the use of in vivo measured flow rates as boundary conditions for image-based hemodynamic models of the human aorta: implications for indicators of abnormal flow. Ann Biomed Eng 40: 729-741.
31. Hall CN, Garthwaite J (2009) What is the real physiological NO concentration in vivo? Nitric Oxide 21: 92-103.
32. Morbiducci U, Ponzini R, Rizzo G, Cadioli M, Esposito A, et al. (2011) Mechanistic insight into the physiological relevance of helical blood flow in the human aorta: an in vivo study. Biomechanics and Modeling in Mechanobiology 10: 339-355.
33. Cheng C, van Haperen R, de Waard M, van Damme LC, Tempel D, et al. (2005) Shear stress affects the intracellular distribution of eNOS: direct demonstration by a novel in vivo technique. Blood 106: 3691-3698.
34. de Nigris F, Lerman LO, Ignarro SW, Sica G, Lerman A, et al. (2004) Beneficial effects of antioxidants and L-arginine on oxidation-sensitive gene expression and endothelial NO synthase activity at sites of disturbed shear stress (vol 100, pg 1420, 2003)
35. . Proc Natl Acad Sci U S A 101: 18262-18262.(2004)
36. Oemar BS, Tschudi MR, Godoy N, Brovkovich V, Malinski T, et al. (1998) Reduced endothelial nitric oxide synthase expression and production in human atherosclerosis. Circulation 97: 2494-2498.
37. Cicha I, Goppelt-Struebe M, Yilmaz A, Daniel WG, Garlichs CD (2008) Endothelial dysfunction and monocyte recruitment in cells exposed to nonuniform shear stress. Clin Hemorheol Microcirc 39: 113-119.
38. Hsiai TK, Hwang J, Barr ML, Correa A, Hamilton R, et al. (2007) Hemodynamics influences vascular peroxynitrite formation: Implication for low-density lipoprotein apo-B-100 nitration. Free Radical Biology and Medicine 42: 519-529.
39. Kuhlencordt PJ, Gyurko R, Han F, Scherrer-Crosbie M, Aretz TH, et al. (2001) Accelerated atherosclerosis, aortic aneurysm formation, and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice. Circulation 104: 448-454.
40. Neishi Y, Mochizuki S, Miyasaka T, Kawamoto T, Kume T, et al. (2005) Evaluation of bioavailability of nitric oxide in coronary circulation by direct measurement of plasma nitric oxide concentration. Proc Natl Acad Sci U S A 102: 11456-11461.
41. Jiang S, Cheng R, Wang X, Xue T, Liu Y, et al. (2013) Real-time electrical detection of nitric oxide in biological systems with sub-nanomolar sensitivity. Nat Commun 4: 2225.
42. Aji W, Ravalli S, Szabolcs M, Jiang XC, Sciacca RR, et al. (1997) L-arginine prevents xanthoma development and inhibits atherosclerosis in LDL receptor knockout mice. Circulation 95: 430-437.
43. Kauser K, da Cunha V, Fitch R, Mallari C, Rubanyi GM (2000) Role of endogenous nitric oxide in progression of atherosclerosis in apolipoprotein Edeficient mice. Am J Physiol Heart Circ Physiol 278: H1679-1685.
44. Reiter CD, Wang X, Tanus-Santos JE, Hogg N, Cannon RO, 3rd, et al. (2002) Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease. Nat Med 8: 1383-1389.
45. Wang H, Luo W, Wang J, Guo C, Wolffe SL, et al. (2013) Paradoxical protection from atherosclerosis and thrombosis in a mouse model of sickle cell disease. Br J Haematol 162: 120-129.
46. Stocker R, Keaney JF, Jr. (2004) Role of oxidative modifications in atherosclerosis. Physiol Rev 84: 1381-1478.
47. Choi HW, Ferrara KW, Barakat AI (2007) Modulation of ATP/ADP concentration at the endothelial surface by shear stress: Effect of flow recirculation. Ann Biomed Eng 35: 505-516.
48. Davies PF (1995) Flow-mediated endothelial mechanotransduction. Physiol Rev 75: 519-560.
49. Plank MJ, Wall DJN, David T (2006) Atherosclerosis and calcium signalling in endothelial cells. Progress in Biophysics & Molecular Biology 91: 287-313.
50. Vandrangi P, Sosa M, Shyy JYJ, Rodgers VGJ (2012) Flow-Dependent Mass Transfer May Trigger Endothelial Signaling Cascades. Plos One 7.
51. Lantz J, Renner J, Karlsson M (2011) Wall Shear Stress in a Subject Specific Human Aorta - Influence of Fluid-Structure Interaction. International Journal of Applied Mechanics 3: 759-778.
52. Balligand JL, Feron O, Dessy C (2009) eNOS activation by physical forces: from short-term regulation of contraction to chronic remodeling of cardiovascular tissues. Physiol Rev 89: 481-534.
53. Boo YC, Jo H (2003) Flow-dependent regulation of endothelial nitric oxide synthase: role of protein kinases. Am J Physiol Cell Physiol 285: C499-508.
54. Kuchan MJ, Frangos JA (1994) Role of calcium and calmodulin in flow-induced nitric oxide production in endothelial cells. Am J Physiol 266: C628-636.