Fracture healing via periosteal callus formation requires macrophages for both initiation and progression of early endochondral ossification

American Journal of Pathology

Volumn 184, Issue 12, 2014, Pages 3192-3204

  Raggatt, Liza J ^a,b   Wullschleger, Martin E ^a,c   Alexander, Kylie A ^b,e   Wu, Andy C K ^b,f   Millard, Susan M ^a   Kaur, Simranpreet ^a,b   Maugham, Michelle L ^a   Gregory, Laura S ^d   Steck, Roland ^d   Pettit, Allison R ^a,b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^d QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^e QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^f TRANSLATIONAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR 1; CYTOKINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE REMODELING; CALLUS; CELL SELECTION; CONTROLLED STUDY; ENCHONDRAL OSSIFICATION; FEMUR FRACTURE; FRACTURE REDUCTION; GRANULATION TISSUE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MACROPHAGE; MOUSE; NONHUMAN; PERIOSTEAL CALLUS FORMATION; ANIMAL; BONE DEVELOPMENT; C57BL MOUSE; CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOLOGY; DISEASE COURSE; FLOW CYTOMETRY; FRACTURE FIXATION; FRACTURE HEALING; INFLAMMATION; INTERNAL FIXATOR; METABOLISM; MONOCYTE; PATHOPHYSIOLOGY; PERIOSTEUM; PHENOTYPE; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOKINES; DISEASE PROGRESSION; FEMORAL FRACTURES; FLOW CYTOMETRY; FRACTURE FIXATION; FRACTURE HEALING; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERNAL FIXATORS; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MONOCYTES; OSTEOGENESIS; PERIOSTEUM; PHENOTYPE;

EID: 84913554539     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2014.08.017     Document Type: Article

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