Emulsion cross-linked chitosan/nanohydroxyapatite microspheres for controlled release of alendronate

Journal of Materials Science: Materials in Medicine

Volumn 25, Issue 12, 2014, Pages 2649-2658

  Wu, Hongwei ^a,c   Xu, Yan ^b   Liu, Gengyan ^a   Ling, Jianghong ^a   Dash, Biraja C ^c   Ruan, Jianming ^b   Zhang, Chaoyue ^a  

^a THE THIRD XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCOMPATIBILITY; BIODEGRADABILITY; CHITOSAN; DRUG PRODUCTS; EFFICIENCY; EMULSIFICATION; MICROSPHERES; MORPHOLOGY; STEM CELLS; SURFACE MORPHOLOGY; TARGETED DRUG DELIVERY; TISSUE; TISSUE ENGINEERING;

ADIPOSE DERIVED STEM CELLS; BONE TISSUE ENGINEERING; COMPOSITE MICROSPHERES; CROSS LINKED CHITOSAN; DRUG-LOADING EFFICIENCY; LOADING EFFICIENCY; NANO-HYDROXYAPATITE; OSTEOGENIC ACTIVITY;

CONTROLLED DRUG DELIVERY;

ALENDRONIC ACID; CHITOSAN; HYDROXYAPATITE; MICROSPHERE; BONE DENSITY CONSERVATION AGENT; CROSS LINKING REAGENT; DELAYED RELEASE FORMULATION; EMULSION; MICROCAPSULE; NANOPARTICLE;

ADIPOSE DERIVED STEM CELL; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; CROSS LINKING; DRUG DISTRIBUTION; EMULSION; HYBRID; IN VITRO STUDY; MICROENVIRONMENT; MORPHOLOGY; NONHUMAN; OSTEOBLAST; SUSTAINED DRUG RELEASE; ADMINISTRATION AND DOSAGE; ANIMAL; BONE DEVELOPMENT; CELL CULTURE; CHEMISTRY; CYTOLOGY; DELAYED RELEASE FORMULATION; DRUG EFFECTS; MICROCAPSULE; PHYSIOLOGY; RABBIT; STEM CELL; SYNTHESIS; ULTRASTRUCTURE;

ALENDRONATE; ANIMALS; BONE DENSITY CONSERVATION AGENTS; CAPSULES; CELL DIFFERENTIATION; CELLS, CULTURED; CHITOSAN; CROSS-LINKING REAGENTS; DELAYED-ACTION PREPARATIONS; DURAPATITE; EMULSIONS; NANOPARTICLES; OSTEOBLASTS; OSTEOGENESIS; RABBITS; STEM CELLS;

EID: 84912150352     PISSN: 09574530     EISSN: 15734838     Source Type: Journal    
DOI: 10.1007/s10856-014-5289-y     Document Type: Article

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