A study on the grafting reaction of isocyanates with hydroxyapatite particles

Journal of Biomedical Materials Research

Volumn 40, Issue 3, 1998, Pages 358-364

  Liu, Q ^a,b,c   De Wijn, J R ^a   Van Blitterswijk, C A ^a,b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b UNIVERSITY OF TWENTE   (Netherlands)

^c Rice University   (United States)

Author keywords

Coupling agents; Hexamethylene diisocyanate; Hydroxyapatite; Hydroxyl groups; Isocyanatoethyl methacrylate; Surface modification

Indexed keywords

GRAFTING (CHEMICAL); INFRARED SPECTROSCOPY; NITROGEN COMPOUNDS; PHOSPHATE MINERALS; SPECTROPHOTOMETRY; SURFACE TREATMENT; THERMOGRAVIMETRIC ANALYSIS;

HYDROXYAPATITE; INFRARED SPECTROPHOTOMETRY; ISOCYANATES;

BIOMATERIALS;

HYDROXYAPATITE; ISOCYANIC ACID DERIVATIVE; METHACRYLIC ACID DERIVATIVE;

ADSORPTION; ARTICLE; BONE GRAFT; BONE PROSTHESIS; DIFFUSION; INFRARED SPECTROPHOTOMETRY; SURFACE PROPERTY;

BONE SUBSTITUTES; DURAPATITE; ISOCYANATES; KINETICS; MATERIALS TESTING; PROSTHESIS IMPLANTATION; SPECTROPHOTOMETRY, INFRARED; SURFACE PROPERTIES;

EID: 0032486491     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4636(19980605)40:3<358::AID-JBM3>3.0.CO;2-E     Document Type: Article

References (18)

1. W. Bonfield, "In vivo evaluation of hydroxyapatite-reinforced polyethylene composite," in Materials Characteristics vs. In Vivo Behaviour, P. Ducheyne and J. E Lemons (eds.), New York Academy of Sciences, New York, 1988, p. 173.
2. K. E. Tanner, C. Doyle, and W. Bonfield, "The strength of the interface developed between biomaterials and bone," in Clinic Implant Materials: Advances in Biomaterials, Vol. 9, G. Heimke, U. Soltesz, and A. J. C. Lee (eds.), Elsevier Science Publishers, Amsterdam, 1990, pp. 149-154.
3. C. Doyle, K. E. Tanner, and W. Bonfield, "In vitro and in vivo evaluation of polyhydroxybutyrate and of polyhydroxybutyrate reinforced with hydroxyapatite," Biomaterials, 12, 841-847 (1991).
4. C. C. P. M. Verheyen, J. R. de Wijn, C. A. van Blitterswijk, P. M. Rozing, and K. de Groot, "Resorbable hydroxyapatite-reinforced poly(L-lactide) composites with bone bonding ability," in Bone-Bonding Biomaterials, P. Ducheyne, T. Kokubo, and C. A. van Blitterswijk (eds.), Reed Healthcare Communications, Leiden, The Netherlands, 1992, pp. 153-171.
5. R. Labella, M. Braden, and S. Deb, "Novel hydroxyapatite-based dental composites," Biomaterals, 15, 1197-1200 (1994).
6. A. M. P. Dupraz, J. R. de Wijn, S. A. T. van der Meer, and K. de Groot, "Characterization of silane-treated hydroxyapatite powders for use as filler in biodegradable composites," J. Biomed. Mater. Res., 30, 231-238 (1996).
7. K. Nishizawa, M. Toriyama, T. Suzuki, Y. Kawamoto, Y. Yokugawa, and F. Nagata, "Surface modification of calcium phosphate ceramics with silane coupling agents," Chem. Soc. Jpn., 1, 63-67 (1995).
8. J. C. Behiri, M. Braden, S. Khorasani, D. Wiwattanadate, and W. Bonfield, "Advanced bone cement for long-term orthopaedic implantations", in Bioceramics, Vol. 4, W. Bonfield, G. W. Hastings, and K. E. Tanner (eds.), Elsevier Science, London, 1991, pp. 301-307.
9. D. N. Misra, "Adsorption of zirconyl salts and their acids on hydroxyapatite: use of the salts as coupling agents to dental polymer composites," J. Dent. Res., 12, 1405-1408 (1985).
10. Q. Liu, J. R. de Wijn, D. Bakker, and C. A. van Blitterswijk, "Surface modification of hydroxyapatite to introduce interfacial bonding with Polyactive™ 70/30 in a biodegradable composite," J. Mater. Sci. Mater. Med., 7, 551-557 (1996).
11. Q. Liu, J. R. de Wijn, M. van Toledo, D. Bakker, and C. A. van Blitterswijk, "Polyacids as bonding agents in hydroxyapatite/polyester-ether (Polyactive™ 30/70) composites," to appear.
12. V. Delpech and A. Lebugle, "Calcium phosphate and interfaces in orthopaedic cement," Clin. Mater., 5, 209-216 (1990).
13. J. Dandurand, V. Delpech, A. Lebugle, A. Lamure, and C. Lacabanne, "Study of the mineral-organic linkage in an apatitic-reinforced bone cement," J. Biomed. Mater. Res., 24, 1377-1384 (1990).
14. Q. Liu, J. R. de Wijn, C. A. van Blitterswijk, "Surface modification of nano-apatite by grafting organic polymer," [Abstract], in Transactions 5th World Biomaterials Congress, Toronto, 1996, p. II-443.
15. J. R. de Wijn, Q. Liu, and C. A. van Blitterswijk, "Grafting PMMA on hydroxyapatite powder particles using isocyanateoethyl methacrylate", [Abstract], in Transactions 5th World Biomaterials Congress, Toronto, 1996, p. I-633.
16. M. D. Lelah and S. L. Cooper, eds., Polyurethanes in Medicine, CRC Press, Boca Raton, Florida, 1996, pp. 21-34.
17. R. W. Lenz, ed., Organic Chemistry of Synthetic High Polymers, Interscience Publishers, New York, 1967, pp. 180-196.
18. D. K. Han, K. D. Park, G. H. Ryu, U. Y. Kim, B. G. Min, and Y. H. Kim, "Plasma protein adsorption to sulfonated poly(ethylene oxide)-grafted polyurethane surface," J. Biomed. Mater. Res., 30, 23-30 (1996).