The Complex I Subunit NDUFA10 Selectively Rescues Drosophila pink1 Mutants through a Mechanism Independent of Mitophagy

PLoS Genetics

Volumn 10, Issue 11, 2014, Pages

  Pogson, Joe H ^a,b   Ivatt, Rachael M ^a,b   Sanchez Martinez, Alvaro ^a,b   Tufi, Roberta ^a,b   Wilson, Emma ^a,b   Mortiboys, Heather ^c   Whitworth, Alexander J ^a,b  

^a Centre for Developmental and Biomedical Genetics   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; PARKIN; PROTEIN ND42; PROTEIN NDUFA10; PROTEIN PINK1; PROTEIN SERINE THREONINE KINASE; PROTEIN SICILY; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SERINE; UNCLASSIFIED DRUG; DROSOPHILA PROTEIN; NDUFA10 PROTEIN, DROSOPHILA; PARKIN PROTEIN, DROSOPHILA; PINK1 PROTEIN, DROSOPHILA; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ARTICLE; CLIMBING; CONTROLLED STUDY; DROSOPHILA; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME SUBUNIT; FLYING; GENE OVEREXPRESSION; GENE SILENCING; INSECT CELL; LOCOMOTION; MITOCHONDRION; MITOPHAGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSGENE; ANIMAL; DISEASE MODEL; DROSOPHILA MELANOGASTER; GENETICS; HUMAN; METABOLISM; MUTATION; PARKINSON DISEASE; PATHOLOGY; PHYSIOLOGY; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ELECTRON TRANSPORT COMPLEX I; HUMANS; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; MUTATION; PARKINSON DISEASE; PROTEIN-SERINE-THREONINE KINASES; UBIQUITIN-PROTEIN LIGASES;

EID: 84912124648     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004815     Document Type: Article

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