메뉴 건너뛰기




Volumn 9, Issue 15, 2014, Pages 2309-2321

Cancer-targeting siRNA delivery from porous silicon nanoparticles

Author keywords

drug delivery; glioblastoma; MRP1; porous silicon nanoparticles; siRNA; ToF SIMS

Indexed keywords

MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 1; NANOCARRIER; POROUS SILICON NANOPARTICLE; SILICON DERIVATIVE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; NANOPARTICLE; PRIMER DNA; SILICON;

EID: 84912089178     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.14.12     Document Type: Article
Times cited : (26)

References (60)
  • 1
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411(6836), 494-498 (2001).
    • (2001) Nature , vol.411 , Issue.6836 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 2
    • 33746228119 scopus 로고    scopus 로고
    • Knocking down disease with siRNAs
    • Dykxhoorn DM, Lieberman J. Knocking down disease with siRNAs. Cell 126(2), 231-235 (2006).
    • (2006) Cell , vol.126 , Issue.2 , pp. 231-235
    • Dykxhoorn, D.M.1    Lieberman, J.2
  • 3
    • 0037329372 scopus 로고    scopus 로고
    • RNA interference is a functional pathway with therapeutic potential in human myeloid leukemia cell lines
    • Cioca DP, Aoki Y, Kiyosawa K. RNA interference is a functional pathway with therapeutic potential in human myeloid leukemia cell lines. Cancer Gene Ther. 10(2), 125-133 (2003).
    • (2003) Cancer Gene Ther. , vol.10 , Issue.2 , pp. 125-133
    • Cioca, D.P.1    Aoki, Y.2    Kiyosawa, K.3
  • 4
    • 84886792794 scopus 로고    scopus 로고
    • Nanoparticle delivery of siRNA as a novel therapeutic for human disease
    • McCarroll J, Kavallaris M. Nanoparticle delivery of siRNA as a novel therapeutic for human disease. Aust. Biochem. 43(3), 9-20 (2012).
    • (2012) Aust. Biochem. , vol.43 , Issue.3 , pp. 9-20
    • McCarroll, J.1    Kavallaris, M.2
  • 5
    • 33751099034 scopus 로고    scopus 로고
    • RNAi therapeutics: A potential new class of pharmaceutical drugs
    • Bumcrot D, Manoharan M, Koteliansky V, Sah DWY. RNAi therapeutics: a potential new class of pharmaceutical drugs. Nat. Chem. Biol. 2(12), 711-719 (2006).
    • (2006) Nat. Chem. Biol. , vol.2 , Issue.12 , pp. 711-719
    • Bumcrot, D.1    Manoharan, M.2    Koteliansky, V.3    Sah, D.W.Y.4
  • 7
    • 0035844237 scopus 로고    scopus 로고
    • The structure of the multidrug resistance protein 1 (MRP1/ABCC1): Crystallization and single-particle analysis
    • Rosenberg MF, Mao Q, Holzenburg A, Ford RC, Deeley RG, Cole SPC. The structure of the multidrug resistance protein 1 (MRP1/ABCC1): crystallization and single-particle analysis. J. Biol. Chem. 276(19), 16076-16082 (2001).
    • (2001) J. Biol. Chem. , vol.276 , Issue.19 , pp. 16076-16082
    • Rosenberg, M.F.1    Mao, Q.2    Holzenburg, A.3    Ford, R.C.4    Deeley, R.G.5    Cole, S.P.C.6
  • 8
    • 67649961691 scopus 로고    scopus 로고
    • Introduction: 2008 Franz edelman award for achievement in operations research and the management sciences
    • Denton BT, Sodhi MS. Introduction: 2008 Franz Edelman Award for Achievement in Operations Research and the Management Sciences. Interfaces 39(1), 2-5 (2009).
    • (2009) Interfaces , vol.39 , Issue.1 , pp. 2-5
    • Denton, B.T.1    Sodhi, M.S.2
  • 9
    • 0031744484 scopus 로고    scopus 로고
    • Activity and expression of the multidrug resistance proteins MRP1 and MRP2 in acute myeloid leukemia cells, tumor cell lines, and normal hematopoietic CD34+ peripheral blood cells
    • van der Kolk DM, de Vries EG, Koning JA, van den Berg E, Müller M, Vellenga E. Activity and expression of the multidrug resistance proteins MRP1 and MRP2 in acute myeloid leukemia cells, tumor cell lines, and normal hematopoietic CD34+ peripheral blood cells. Clin. Cancer Res. 4(7), 1727-1736 (1998).
    • (1998) Clin. Cancer Res. , vol.4 , Issue.7 , pp. 1727-1736
    • Van Der Kolk, D.M.1    De Vries, E.G.2    Koning, J.A.3    Van Den Berg, E.4    Müller, M.5    Vellenga, E.6
  • 10
    • 0027506202 scopus 로고
    • Induction of multidrug resistance in human cells by transient exposure to different chemotherapeutic drugs
    • Chaudhary PM, Roninson IB. Induction of multidrug resistance in human cells by transient exposure to different chemotherapeutic drugs. J. Natl Cancer Inst. 85(8), 632-639 (1993).
    • (1993) J. Natl Cancer Inst. , vol.85 , Issue.8 , pp. 632-639
    • Chaudhary, P.M.1    Roninson, I.B.2
  • 11
    • 0037314795 scopus 로고    scopus 로고
    • RNA expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: Correlation with chemotherapeutic response
    • Burger H, Foekens JA, Look MP et al. RNA expression of breast cancer resistance protein, lung resistance-related protein, multidrug resistance-associated proteins 1 and 2, and multidrug resistance gene 1 in breast cancer: correlation with chemotherapeutic response. Clin. Cancer Res. 9(2), 827-836 (2003).
    • (2003) Clin. Cancer Res. , vol.9 , Issue.2 , pp. 827-836
    • Burger, H.1    Foekens, J.A.2    Look, M.P.3
  • 12
    • 3042655528 scopus 로고    scopus 로고
    • Membrane transporters and channels: Role of the transportome in cancer chemosensitivity and chemoresistance
    • Huang Y, Anderle P, Bussey KJ et al. Membrane transporters and channels: role of the transportome in cancer chemosensitivity and chemoresistance. Cancer Res. 64(12), 4294-4301 (2004).
    • (2004) Cancer Res. , vol.64 , Issue.12 , pp. 4294-4301
    • Huang, Y.1    Anderle, P.2    Bussey, K.J.3
  • 13
    • 67249106291 scopus 로고    scopus 로고
    • Coadministration of paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells
    • Ganta S, Amiji M. Coadministration of paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells. Mol. Pharmaceut. 6(3), 928-939 (2009).
    • (2009) Mol. Pharmaceut. , vol.6 , Issue.3 , pp. 928-939
    • Ganta, S.1    Amiji, M.2
  • 14
    • 54249087596 scopus 로고    scopus 로고
    • RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy
    • Singh A, Boldin-Adamsky S, Thimmulappa RK et al. RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy. Cancer Res. 68(19), 7975-7984 (2008).
    • (2008) Cancer Res. , vol.68 , Issue.19 , pp. 7975-7984
    • Singh, A.1    Boldin-Adamsky, S.2    Thimmulappa, R.K.3
  • 15
    • 78149471362 scopus 로고    scopus 로고
    • Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells
    • Kato T, Natsume A, Toda H et al. Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells. Gene Ther. 17(11), 1363-1371 (2010).
    • (2010) Gene Ther. , vol.17 , Issue.11 , pp. 1363-1371
    • Kato, T.1    Natsume, A.2    Toda, H.3
  • 16
    • 0034527893 scopus 로고    scopus 로고
    • Expression of multidrug resistance-associated protein (MRP) in human gliomas
    • Mohri M, Nitta H, Yamashita J. Expression of multidrug resistance-associated protein (MRP) in human gliomas. J. Neuro-Oncol. 49(2), 105-115 (2000).
    • (2000) J. Neuro-Oncol. , vol.49 , Issue.2 , pp. 105-115
    • Mohri, M.1    Nitta, H.2    Yamashita, J.3
  • 17
    • 0036498029 scopus 로고    scopus 로고
    • In vitro and in vivo downregulation of MRP1 by antisense oligonucleotides: A potential role in neuroblastoma therapy
    • Kuss BJ, Corbo M, Lau WM, Fennell DA, Dean NM, Cotter FE. In vitro and in vivo downregulation of MRP1 by antisense oligonucleotides: a potential role in neuroblastoma therapy. Int. J. Cancer 98(1), 128-133 (2002).
    • (2002) Int. J. Cancer , vol.98 , Issue.1 , pp. 128-133
    • Kuss, B.J.1    Corbo, M.2    Lau, W.M.3    Fennell, D.A.4    Dean, N.M.5    Cotter, F.E.6
  • 18
    • 80051807240 scopus 로고    scopus 로고
    • Assessing multidrug resistance protein 1-mediated function in cancer cell multidrug resistance by scanning electrochemical microscopy and flow cytometry
    • Kuss S, Cornut R, Beaulieu I, Mezour MA, Annabi B, Mauzeroll J. Assessing multidrug resistance protein 1-mediated function in cancer cell multidrug resistance by scanning electrochemical microscopy and flow cytometry. Bioelectrochemistry 82(1), 29-37 (2011).
    • (2011) Bioelectrochemistry , vol.82 , Issue.1 , pp. 29-37
    • Kuss, S.1    Cornut, R.2    Beaulieu, I.3    Mezour, M.A.4    Annabi, B.5    Mauzeroll, J.6
  • 19
  • 21
    • 84861880834 scopus 로고    scopus 로고
    • Efficient functional delivery of siRNA using mesoporous silica nanoparticles with ultralarge pores
    • Na H-K, Kim M-H, Park K et al. Efficient functional delivery of siRNA using mesoporous silica nanoparticles with ultralarge pores. Small 8(11), 1752-1761 (2012).
    • (2012) Small , vol.8 , Issue.11 , pp. 1752-1761
    • Na, H.-K.1    Kim, M.-H.2    Park, K.3
  • 22
    • 84856389509 scopus 로고    scopus 로고
    • RNA-based therapeutics: Current progress and future prospects
    • Burnett JC, Rossi JJ. RNA-based therapeutics: current progress and future prospects. Chem. Biol. 19(1), 60-71 (2012).
    • (2012) Chem. Biol. , vol.19 , Issue.1 , pp. 60-71
    • Burnett, J.C.1    Rossi, J.J.2
  • 23
    • 78449309070 scopus 로고    scopus 로고
    • Efficient and targeted delivery of siRNA in vivo
    • Shim MS, Kwon YJ. Efficient and targeted delivery of siRNA in vivo. FEBS J. 277(23), 4814-4827 (2010).
    • (2010) FEBS J. , vol.277 , Issue.23 , pp. 4814-4827
    • Shim, M.S.1    Kwon, Y.J.2
  • 24
    • 70449094064 scopus 로고    scopus 로고
    • Photoluminescence-based sensing with porous silicon films, microparticles, and nanoparticles
    • Sailor MJ, Wu EC. Photoluminescence-based sensing with porous silicon films, microparticles, and nanoparticles. Adv. Funct. Mater. 19(20), 3195-3208 (2009).
    • (2009) Adv. Funct. Mater. , vol.19 , Issue.20 , pp. 3195-3208
    • Sailor, M.J.1    Wu, E.C.2
  • 26
    • 84860746210 scopus 로고    scopus 로고
    • Cellular interactions of surface modified nanoporous silicon particles
    • Bimbo LM, Sarparanta M, Makila E et al. Cellular interactions of surface modified nanoporous silicon particles. Nanoscale 4(10), 3184-3192 (2012).
    • (2012) Nanoscale , vol.4 , Issue.10 , pp. 3184-3192
    • Bimbo, L.M.1    Sarparanta, M.2    Makila, E.3
  • 27
    • 62149104779 scopus 로고    scopus 로고
    • The biocompatibility of porous silicon in tissues of the eye
    • Low SP, Voelcker NH, Canham LT, Williams KA. The biocompatibility of porous silicon in tissues of the eye. Biomaterials 30(15), 2873-2880 (2009).
    • (2009) Biomaterials , vol.30 , Issue.15 , pp. 2873-2880
    • Low, S.P.1    Voelcker, N.H.2    Canham, L.T.3    Williams, K.A.4
  • 28
    • 40449122225 scopus 로고    scopus 로고
    • Mesoporous silicon particles as a multistage delivery system for imaging and therapeutic applications
    • Tasciotti E, Liu X, Bhavane R et al. Mesoporous silicon particles as a multistage delivery system for imaging and therapeutic applications. Nat. Nano. 3(3), 151-157 (2008).
    • (2008) Nat. Nano. , vol.3 , Issue.3 , pp. 151-157
    • Tasciotti, E.1    Liu, X.2    Bhavane, R.3
  • 29
    • 84856572415 scopus 로고    scopus 로고
    • The mucoadhesive and gastroretentive properties of hydrophobin-coated porous silicon nanoparticle oral drug delivery systems
    • Sarparanta MP, Bimbo LM, Mäkilä EM et al. The mucoadhesive and gastroretentive properties of hydrophobin-coated porous silicon nanoparticle oral drug delivery systems. Biomaterials 33(11), 3353-3362 (2012).
    • (2012) Biomaterials , vol.33 , Issue.11 , pp. 3353-3362
    • Sarparanta, M.P.1    Bimbo, L.M.2    Mäkilä, E.M.3
  • 31
    • 77953414570 scopus 로고    scopus 로고
    • Silicon-polymer hybrid materials for drug delivery
    • McInnes SJP, Voelcker NH. Silicon-polymer hybrid materials for drug delivery. Future Med. Chem. 1(6), 1051-1074 (2009).
    • (2009) Future Med. Chem. , vol.1 , Issue.6 , pp. 1051-1074
    • McInnes, S.J.P.1    Voelcker, N.H.2
  • 32
    • 79959219339 scopus 로고    scopus 로고
    • Stimulus-responsiveness and drug release from porous silicon films ATRP-grafted with poly(N-isopropylacrylamide)
    • Vasani RB, McInnes SJP, Cole MA, Jani AMM, Ellis AV, Voelcker NH. Stimulus-responsiveness and drug release from porous silicon films ATRP-grafted with poly(N-isopropylacrylamide). Langmuir 27(12), 7843-7853 (2011).
    • (2011) Langmuir , vol.27 , Issue.12 , pp. 7843-7853
    • Vasani, R.B.1    McInnes, S.J.P.2    Cole, M.A.3    Jani, A.M.M.4    Ellis, A.V.5    Voelcker, N.H.6
  • 33
    • 79958841674 scopus 로고    scopus 로고
    • PH-operated mechanized porous silicon nanoparticles
    • Xue M, Zhong X, Shaposhnik Z et al. pH-operated mechanized porous silicon nanoparticles. J. Am. Chem. Soc. 133(23), 8798-8801 (2011).
    • (2011) J. Am. Chem. Soc. , vol.133 , Issue.23 , pp. 8798-8801
    • Xue, M.1    Zhong, X.2    Shaposhnik, Z.3
  • 34
    • 77951699994 scopus 로고    scopus 로고
    • Sustained small interfering RNA delivery by mesoporous silicon particles
    • Tanaka T, Mangala LS, Vivas-Mejia PE et al. Sustained small interfering RNA delivery by mesoporous silicon particles. Cancer Res. 70(9), 3687-3696 (2010).
    • (2010) Cancer Res. , vol.70 , Issue.9 , pp. 3687-3696
    • Tanaka, T.1    Mangala, L.S.2    Vivas-Mejia, P.E.3
  • 35
    • 84877658682 scopus 로고    scopus 로고
    • Multistage vectored siRNA targeting ataxia-telangiectasia mutated for breast cancer therapy
    • Xu R, Huang Y, Mai J et al. Multistage vectored siRNA targeting ataxia-telangiectasia mutated for breast cancer therapy. Small 9(9-10), 1799-1808 (2013).
    • (2013) Small , vol.9 , Issue.9-10 , pp. 1799-1808
    • Xu, R.1    Huang, Y.2    Mai, J.3
  • 36
    • 80051502248 scopus 로고    scopus 로고
    • Porous silicon nanoparticle photosensitizers for singlet oxygen and their phototoxicity against cancer cells
    • Xiao L, Gu L, Howell SB, Sailor MJ. porous silicon nanoparticle photosensitizers for singlet oxygen and their phototoxicity against cancer cells. ACS Nano 5(5), 3651-3659 (2011).
    • (2011) ACS Nano , vol.5 , Issue.5 , pp. 3651-3659
    • Xiao, L.1    Gu, L.2    Howell, S.B.3    Sailor, M.J.4
  • 37
    • 84255167522 scopus 로고    scopus 로고
    • Porous silicon nanoparticles for cancer photothermotherapy
    • Hong C, Lee J, Zheng H, Hong S-S, Lee C. Porous silicon nanoparticles for cancer photothermotherapy. Nanoscale Res. Lett. 6(1), 321 (2011).
    • (2011) Nanoscale Res. Lett. , vol.6 , Issue.1 , pp. 321
    • Hong, C.1    Lee, J.2    Zheng, H.3    Hong, S.-S.4    Lee, C.5
  • 38
    • 84879608162 scopus 로고    scopus 로고
    • Antibody-functionalized porous silicon nanoparticles for vectorization of hydrophobic drugs
    • Secret E, Smith K, Dubljevic V et al. Antibody-functionalized porous silicon nanoparticles for vectorization of hydrophobic drugs. Adv. Healthc. Mater. 2(5), 718-727 (2012).
    • (2012) Adv. Healthc. Mater. , vol.2 , Issue.5 , pp. 718-727
    • Secret, E.1    Smith, K.2    Dubljevic, V.3
  • 39
    • 84858964932 scopus 로고    scopus 로고
    • Fabrication and characterization of porous silicon nanoparticles for siRNA delivery
    • Presented at Portland, OR, USA, 15-19 August
    • Kopermsub P, Mayen V, McInnes S, Voelcker NH. Fabrication and characterization of porous silicon nanoparticles for siRNA delivery. Presented at: 11th IEEE Conference on Nanotechnology. Portland, OR, USA, 830-832, 15-19 August 2011.
    • (2011) 11th IEEE Conference on Nanotechnology , pp. 830-832
    • Kopermsub, P.1    Mayen, V.2    McInnes, S.3    Voelcker, N.H.4
  • 40
    • 34250001748 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles deliver DNA and chemicals into plants
    • Torney F, Trewyn BG, Lin VSY, Wang K. Mesoporous silica nanoparticles deliver DNA and chemicals into plants. Nat. Nano. 2(5), 295-300 (2007).
    • (2007) Nat. Nano. , vol.2 , Issue.5 , pp. 295-300
    • Torney, F.1    Trewyn, B.G.2    Lin, V.S.Y.3    Wang, K.4
  • 41
    • 80053580456 scopus 로고    scopus 로고
    • The packaging of siRNA within the mesoporous structure of silica nanoparticles
    • Li X, Xie QR, Zhang J, Xia W, Gu H. The packaging of siRNA within the mesoporous structure of silica nanoparticles. Biomaterials 32(35), 9546-9556 (2011).
    • (2011) Biomaterials , vol.32 , Issue.35 , pp. 9546-9556
    • Li, X.1    Xie, Q.R.2    Zhang, J.3    Xia, W.4    Gu, H.5
  • 42
    • 77953235193 scopus 로고    scopus 로고
    • Nanoparticle technologies for cancer therapy
    • Schäfer-Korting M (Ed.). Springer, Berlin, Germany
    • Alexis F, Pridgen E, Langer R, Farokhzad O. Nanoparticle technologies for cancer therapy. In: Drug Delivery. Schäfer-Korting M (Ed.). Springer, Berlin, Germany, 55-86 (2010).
    • (2010) Drug Delivery , pp. 55-86
    • Alexis, F.1    Pridgen, E.2    Langer, R.3    Farokhzad, O.4
  • 44
    • 34248402413 scopus 로고    scopus 로고
    • Shape effects of filaments versus spherical particles in flow and drug delivery
    • Geng Y, Dalhaimer P, Cai S et al. Shape effects of filaments versus spherical particles in flow and drug delivery. Nat. Nano. 2(4), 249-255 (2007).
    • (2007) Nat. Nano. , vol.2 , Issue.4 , pp. 249-255
    • Geng, Y.1    Dalhaimer, P.2    Cai, S.3
  • 45
    • 79952852964 scopus 로고    scopus 로고
    • Modeling particle shape-dependent dynamics in nanomedicine
    • Shah S, Liu Y, Hu W, Gao J. Modeling particle shape-dependent dynamics in nanomedicine. J. Nanosci. Nanotech. 11(2), 919 (2011).
    • (2011) J. Nanosci. Nanotech. , vol.11 , Issue.2 , pp. 919
    • Shah, S.1    Liu, Y.2    Hu, W.3    Gao, J.4
  • 46
    • 75549087322 scopus 로고    scopus 로고
    • Size and shape effects in the biodistribution of intravascularly injected particles
    • Decuzzi P, Godin B, Tanaka T et al. Size and shape effects in the biodistribution of intravascularly injected particles. J. Control. Release 141(3), 320-327 (2010).
    • (2010) J. Control. Release , vol.141 , Issue.3 , pp. 320-327
    • Decuzzi, P.1    Godin, B.2    Tanaka, T.3
  • 47
    • 0035356576 scopus 로고    scopus 로고
    • A factorial analysis of silanization conditions for the immobilization of oligonucleotides on glass surfaces
    • Halliwell CM, Cass AEG. A factorial analysis of silanization conditions for the immobilization of oligonucleotides on glass surfaces. Anal. Chem. 73(11), 2476-2483 (2001).
    • (2001) Anal. Chem. , vol.73 , Issue.11 , pp. 2476-2483
    • Halliwell, C.M.1    Cass, A.E.G.2
  • 48
    • 84869770464 scopus 로고    scopus 로고
    • Photoluminescence enhancement of porous silicon particles by microwave-assisted activation
    • Xia B, Zhang W, Bao W, Dong C, Zhang J, Shi J. Photoluminescence enhancement of porous silicon particles by microwave-assisted activation. Phys. Status Solidi (A) 209(11), 2247-2250 (2012).
    • (2012) Phys. Status Solidi (A) , vol.209 , Issue.11 , pp. 2247-2250
    • Xia, B.1    Zhang, W.2    Bao, W.3    Dong, C.4    Zhang, J.5    Shi, J.6
  • 49
    • 0037051030 scopus 로고    scopus 로고
    • Organic functionalization of group IV semiconductor surfaces: Principles, examples, applications, and prospects
    • Bent SF. Organic functionalization of group IV semiconductor surfaces: principles, examples, applications, and prospects. Surf. Sci. 500(1-3), 879-903 (2002).
    • (2002) Surf. Sci. , vol.500 , Issue.1-3 , pp. 879-903
    • Bent, S.F.1
  • 50
    • 26244441643 scopus 로고    scopus 로고
    • Nanostructure-mediated drug delivery
    • Hughes GA. Nanostructure-mediated drug delivery. Nanomed. Nanotech. Biol. Med. 1(1), 22-30 (2005).
    • (2005) Nanomed. Nanotech. Biol. Med. , vol.1 , Issue.1 , pp. 22-30
    • Hughes, G.A.1
  • 51
    • 84859127335 scopus 로고    scopus 로고
    • Delivery of small interfering RNA by peptide-targeted mesoporous silica nanoparticle-supported lipid bilayers
    • Ashley CE, Carnes EC, Epler KE et al. Delivery of small interfering RNA by peptide-targeted mesoporous silica nanoparticle-supported lipid bilayers. ACS Nano 6(3), 2174-2188 (2012).
    • (2012) ACS Nano , vol.6 , Issue.3 , pp. 2174-2188
    • Ashley, C.E.1    Carnes, E.C.2    Epler, K.E.3
  • 52
    • 34548588415 scopus 로고    scopus 로고
    • Dendrimer-modified magnetic nanoparticles enhance efficiency of gene delivery system
    • Pan B, Cui D, Sheng Y et al. Dendrimer-modified magnetic nanoparticles enhance efficiency of gene delivery system. Cancer Res. 67(17), 8156-8163 (2007).
    • (2007) Cancer Res. , vol.67 , Issue.17 , pp. 8156-8163
    • Pan, B.1    Cui, D.2    Sheng, Y.3
  • 53
    • 74049124186 scopus 로고    scopus 로고
    • Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application
    • Jackson AL, Linsley PS. Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application. Nat. Rev. Drug Discov. 9(1), 57-67 (2010).
    • (2010) Nat. Rev. Drug Discov. , vol.9 , Issue.1 , pp. 57-67
    • Jackson, A.L.1    Linsley, P.S.2
  • 54
    • 4744373229 scopus 로고    scopus 로고
    • Noise amidst the silence: Off-target effects of siRNAs?
    • Jackson AL, Linsley PS. Noise amidst the silence: off-target effects of siRNAs? Trends in Genet. 20(11), 521-524 (2004).
    • (2004) Trends in Genet. , vol.20 , Issue.11 , pp. 521-524
    • Jackson, A.L.1    Linsley, P.S.2
  • 55
    • 27844495150 scopus 로고    scopus 로고
    • Current developments in gene transfection agents
    • Azzam T, Domb AJ. Current developments in gene transfection agents. Curr. Drug delivery, 1(2), 165-193 (2004).
    • (2004) Curr. Drug Delivery , vol.1 , Issue.2 , pp. 165-193
    • Azzam, T.1    Domb, A.J.2
  • 57
    • 77953168018 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles facilitate delivery of siRNA to shutdown signaling pathways in mammalian cells
    • Hom C, Lu J, Liong M et al. Mesoporous silica nanoparticles facilitate delivery of siRNA to shutdown signaling pathways in mammalian cells. Small 6(11), 1185-1190 (2010).
    • (2010) Small , vol.6 , Issue.11 , pp. 1185-1190
    • Hom, C.1    Lu, J.2    Liong, M.3
  • 58
    • 70350639581 scopus 로고    scopus 로고
    • Polyethyleneimine coating enhances the cellular uptake of mesoporous silica nanoparticles and allows safe delivery of siRNA and DNA constructs
    • Xia T, Kovochich M, Liong M et al. Polyethyleneimine coating enhances the cellular uptake of mesoporous silica nanoparticles and allows safe delivery of siRNA and DNA constructs. ACS Nano 3(10), 3273-3286 (2009).
    • (2009) ACS Nano , vol.3 , Issue.10 , pp. 3273-3286
    • Xia, T.1    Kovochich, M.2    Liong, M.3
  • 59
    • 77953303124 scopus 로고    scopus 로고
    • Toxicity pathway focused gene expression profiling of PEI-based polymers for pulmonary applications
    • Beyerle A, Irmler M, Beckers J, Kissel T, Stoeger T. toxicity pathway focused gene expression profiling of PEI-based polymers for pulmonary applications. Mol. Pharmaceut. 7(3), 727-737 (2010).
    • (2010) Mol. Pharmaceut. , vol.7 , Issue.3 , pp. 727-737
    • Beyerle, A.1    Irmler, M.2    Beckers, J.3    Kissel, T.4    Stoeger, T.5
  • 60
    • 67650479404 scopus 로고    scopus 로고
    • Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug
    • MacDiarmid JA, Amaro-Mugridge NB, Madrid-Weiss J et al. Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug. Nat. Biotech. 27(7), 643-651 (2009).
    • (2009) Nat. Biotech. , vol.27 , Issue.7 , pp. 643-651
    • Macdiarmid, J.A.1    Amaro-Mugridge, N.B.2    Madrid-Weiss, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.