-
1
-
-
12344273726
-
The blood-brain barrier: Bottleneck in brain drug development
-
Pardridge WM. The blood-brain barrier: bottleneck in brain drug development. NeuroRx 2(1), 3-14 (2005).
-
(2005)
NeuroRx
, vol.2
, Issue.1
, pp. 3-14
-
-
Pardridge, W.M.1
-
2
-
-
33845784758
-
Blood-brain barrier delivery
-
Pardridge WM. Blood-brain barrier delivery. Drug Discov. Today 12(1-2), 54-61 (2007).
-
(2007)
Drug Discov. Today
, vol.12
, Issue.1-2
, pp. 54-61
-
-
Pardridge, W.M.1
-
3
-
-
0021586266
-
-
Fact sheet no 297
-
WHO. Cancer, Fact sheet no 297 (2014). www.who.int/mediacentre/factsheets/fs297/en/ 4 Tomalia DA, Baker H, Dewald J et al. A new class of polymers: starburst-dendritic macromolecules. Polym. J. 17, 117-132 (1985).
-
(2014)
Cancer
-
-
WHO1
-
4
-
-
77949275122
-
Dendrimer-based drug and imaging conjugates: Design considerations for nanomedical applications
-
Menjoge AR, Kannan RM, Tomalia DA. Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications. Drug Discov. Today 15(5-6), 171-185 (2010).
-
(2010)
Drug Discov. Today
, vol.15
, Issue.5-6
, pp. 171-185
-
-
Menjoge, A.R.1
Kannan, R.M.2
Tomalia, D.A.3
-
5
-
-
84989581991
-
'Cascade' and 'nonskid-chain-like' syntheses of molecular cavity topologies
-
Buhleier E, Wehner W, Vögtle F. 'Cascade' and 'nonskid-chain-like' syntheses of molecular cavity topologies. Synthesis 2, 155-158 (1978).
-
(1978)
Synthesis
, vol.2
, pp. 155-158
-
-
Buhleier, E.1
Wehner, W.2
Vögtle, F.3
-
6
-
-
30244557628
-
Dendritic macromolecules -synthesis of starburst dendrimers
-
Tomalia DA, Baker H, Dewald J et al. Dendritic macromolecules -synthesis of starburst dendrimers. Macromolecules 19, 2466-2468 (1986).
-
(1986)
Macromolecules
, vol.19
, pp. 2466-2468
-
-
Tomalia, D.A.1
Baker, H.2
Dewald, J.3
-
7
-
-
33845378981
-
Micelles. Part 1. Cascade molecules -a new approach to micelles -a [27]-arborol
-
Newkome GR, Yao ZQ, Baker GR, Gupta VK. Micelles. Part 1. Cascade molecules -a new approach to micelles -a [27]-arborol. J. Org. Chem. 50, 2003-2004 (1985).
-
(1985)
J. Org. Chem.
, vol.50
, pp. 2003-2004
-
-
Newkome, G.R.1
Yao, Z.Q.2
Baker, G.R.3
Gupta, V.K.4
-
8
-
-
33845373853
-
Cascade molecules. Part 2. Synthesis and characterization of a benzene [9]3-arborol
-
Newkome GR, Yao ZQ, Baker GR, Gupta VK, Russo PS, Saunders MJ. Cascade molecules. Part 2. Synthesis and characterization of a benzene [9]3-arborol. J. Am. Chem. Soc. 108, 849-850 (1986).
-
(1986)
J. Am. Chem. Soc
, vol.108
, pp. 849-850
-
-
Newkome, G.R.1
Yao, Z.Q.2
Baker, G.R.3
Gupta, V.K.4
Russo, P.S.5
Saunders, M.J.6
-
9
-
-
0035342007
-
Poly (amidoamine) (PAMAM) dendrimers: From biomimicry to drug delivery and biomedical applications
-
Esfand R, Tomalia DA. Poly (amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications. Drug Discov. Today 6(8), 427-436 (2001).
-
(2001)
Drug Discov. Today
, vol.6
, Issue.8
, pp. 427-436
-
-
Esfand, R.1
Tomalia, D.A.2
-
10
-
-
0038817081
-
Preparation of polymers with controlled molecular architecture -a new convergent approach to dendritic macromolecules
-
Hawker CJ, Fréchet JMJ. Preparation of polymers with controlled molecular architecture -a new convergent approach to dendritic macromolecules. J. Am. Chem. Soc. 112, 7638-7647 (1990).
-
(1990)
J. Am. Chem. Soc.
, vol.112
, pp. 7638-7647
-
-
Hawker, C.J.1
Fréchet, J.M.J.2
-
11
-
-
0344466792
-
Designing dendrimers for drug delivery
-
Liu M, Fréchet JMJ. Designing dendrimers for drug delivery. Pharm. Sci. Technol. Today 2(10), 393-401 (1999).
-
(1999)
Pharm. Sci. Technol. Today
, vol.2
, Issue.10
, pp. 393-401
-
-
Liu, M.1
Fréchet, J.M.J.2
-
12
-
-
78650316044
-
Biomedical applications of dendrimers: A tutorial
-
Mintzer MA, Grinstaff MW. Biomedical applications of dendrimers: a tutorial. Chem. Soc. Rev. 40(1), 173-190 (2011).
-
(2011)
Chem. Soc. Rev.
, vol.40
, Issue.1
, pp. 173-190
-
-
Mintzer, M.A.1
Grinstaff, M.W.2
-
13
-
-
84892686901
-
Dendrimer advances for the central nervous system delivery of therapeutics
-
Xu L, Zhang H, Wu Y. Dendrimer advances for the central nervous system delivery of therapeutics. ACS Chem. Neurosci. 5(1), 2-13 (2014).
-
(2014)
ACS Chem. Neurosci.
, vol.5
, Issue.1
, pp. 2-13
-
-
Xu, L.1
Zhang, H.2
Wu, Y.3
-
14
-
-
43449117468
-
Therapeutic and diagnostic applications of dendrimers for cancer treatment
-
Wolinsky JB, Grinstaff MW. Therapeutic and diagnostic applications of dendrimers for cancer treatment. Adv. Drug Deliv. Rev. 60(9), 1037-1055 (2008).
-
(2008)
Adv. Drug Deliv. Rev.
, vol.60
, Issue.9
, pp. 1037-1055
-
-
Wolinsky, J.B.1
Grinstaff, M.W.2
-
15
-
-
0030099527
-
Transporting therapeutics across the blood-brain barrier
-
Abbott NJ, Romero IA. Transporting therapeutics across the blood-brain barrier. Mol. Med. Today 2, 106-113 (1996).
-
(1996)
Mol. Med. Today
, vol.2
, pp. 106-113
-
-
Abbott, N.J.1
Romero, I.A.2
-
16
-
-
0033968049
-
Endothelial vesicles in the blood-brain barrier: Are they related to permeability?
-
Stewart PA. Endothelial vesicles in the blood-brain barrier: are they related to permeability? Cell. Mol. Neurobiol. 20, 149-163 (2000).
-
(2000)
Cell. Mol. Neurobiol.
, vol.20
, pp. 149-163
-
-
Stewart, P.A.1
-
17
-
-
33646450620
-
Physiology of the blood-brain barrier and its consequences for drug transport to the brain
-
Abbott, NJ. Physiology of the blood-brain barrier and its consequences for drug transport to the brain. Int. Congr. Ser. 1277, 3-18 (2005).
-
(2005)
Int. Congr. Ser.
, vol.1277
, pp. 3-18
-
-
Abbott, N.J.1
-
18
-
-
33747368249
-
Blood-brain barrier: Structural components and function under physiologic and pathologic conditions
-
Persidsky Y, Ramirez SH, Haorah J, Kanmogne GD. Blood-brain barrier: structural components and function under physiologic and pathologic conditions. J. Neuroimmune Pharmacol. 1, 223-236 (2006).
-
(2006)
J. Neuroimmune Pharmacol.
, vol.1
, pp. 223-236
-
-
Persidsky, Y.1
Ramirez, S.H.2
Haorah, J.3
Kanmogne, G.D.4
-
19
-
-
29244463365
-
Astrocyte-endothelial interactions at the blood-brain barrier
-
Abbott NJ, Rönnbäck L, Hansson E. Astrocyte-endothelial interactions at the blood-brain barrier. Nat. Rev. Neurosci. 7, 41-53 (2006).
-
(2006)
Nat. Rev. Neurosci.
, vol.7
, pp. 41-53
-
-
Abbott, N.J.1
Rönnbäck, L.2
Hansson, E.3
-
20
-
-
0021130764
-
Transferrin receptor on endothelium of brain capillaries
-
Jefferies WA, Brandon MR, Hunt SV, Williams AF, Gatter KC, Mason DY. Transferrin receptor on endothelium of brain capillaries. Nature 312, 162-163 (1984).
-
(1984)
Nature
, vol.312
, pp. 162-163
-
-
Jefferies, W.A.1
Brandon, M.R.2
Hunt, S.V.3
Williams, A.F.4
Gatter, K.C.5
Mason, D.Y.6
-
21
-
-
84877640881
-
Transferrin and the transferrin receptor for the targeted delivery of therapeutic agents to the brain and cancer cells
-
Dufès C, Al Robaian M, Somani S. Transferrin and the transferrin receptor for the targeted delivery of therapeutic agents to the brain and cancer cells, Ther. Deliv. 4, 629-640 (2013).
-
(2013)
Ther Deliv.
, vol.4
, pp. 629-640
-
-
Dufès, C.1
Al Robaian, M.2
Somani, S.3
-
22
-
-
33947625559
-
Efficient gene delivery targeted to the brain using a transferrin-conjugated polyethyleneglycol-modified polyamidoamine dendrimer
-
Huang RQ, Qu YH, Ke WL, Zhu JH, Pei YY, Jiang C. Efficient gene delivery targeted to the brain using a transferrin-conjugated polyethyleneglycol-modified polyamidoamine dendrimer. FASEB J. 21, 1117-1125 (2007).
-
(2007)
FASEB J.
, vol.21
, pp. 1117-1125
-
-
Huang, R.Q.1
Qu, Y.H.2
Ke, W.L.3
Zhu, J.H.4
Pei, Y.Y.5
Jiang, C.6
-
23
-
-
0034962525
-
Histochemical characterization of primary capillary endothelial cells from porcine brains using monoclonal antibodies and fluorescein isothiocyanate-labelled lectins: Implications for drug delivery
-
Fisher D, Kissel T. Histochemical characterization of primary capillary endothelial cells from porcine brains using monoclonal antibodies and fluorescein isothiocyanate-labelled lectins: implications for drug delivery. Eur. J. Pharm. Biopharm. 52, 1-11 (2001).
-
(2001)
Eur. J. Pharm. Biopharm.
, vol.52
, pp. 1-11
-
-
Fisher, D.1
Kissel, T.2
-
24
-
-
27744508956
-
Paclitaxel-loaded PLGA nanoparticles: Potentiation of anticancer activity by surface conjugation
-
Mo Y, Lim, L. Paclitaxel-loaded PLGA nanoparticles: potentiation of anticancer activity by surface conjugation. J. Control. Release 108, 244-262 (2005).
-
(2005)
J. Control. Release
, vol.108
, pp. 244-262
-
-
Mo, Y.1
Lim, L.2
-
25
-
-
78449252867
-
PEGylated poly(amidoamine) dendrimer-based dual-targeting carrier for treating brain tumors
-
He H, Li Y, Jia XR et al. PEGylated poly(amidoamine) dendrimer-based dual-targeting carrier for treating brain tumors. Biomaterials 32(2), 478-487 (2011).
-
(2011)
Biomaterials
, vol.32
, Issue.2
, pp. 478-487
-
-
He, H.1
Li, Y.2
Jia, X.R.3
-
26
-
-
33644810414
-
Lack of interactions between breast cancer resistance protein (BCRP/ABCG2) and selected antiepileptic agents
-
Cerveny L, Pavek P, Malakova J, Staud F, Fendrich Z. Lack of interactions between breast cancer resistance protein (BCRP/ABCG2) and selected antiepileptic agents. Epilepsia 47(3), 461-468 (2006).
-
(2006)
Epilepsia
, vol.47
, Issue.3
, pp. 461-468
-
-
Cerveny, L.1
Pavek, P.2
Malakova, J.3
Staud, F.4
Fendrich, Z.5
-
27
-
-
77955845912
-
Enhanced efficacy of functionalized epirubicin liposomes in treating brain glioma-bearing rats
-
Tian W, Ying X, Du J et al. Enhanced efficacy of functionalized epirubicin liposomes in treating brain glioma-bearing rats. Eur. J. Pharm. Sci. 41(2), 232-243 (2010).
-
(2010)
Eur. J. Pharm. Sci.
, vol.41
, Issue.2
, pp. 232-243
-
-
Tian, W.1
Ying, X.2
Du, J.3
-
28
-
-
0023942946
-
Tamoxifen counteracts estradiol induced effects on striatal and hypophyseal dopamine receptors
-
Ferretti C, Blengio M, Ghi P, Racca S, Genazzani E, Portaleone P. Tamoxifen counteracts estradiol induced effects on striatal and hypophyseal dopamine receptors. Life Sci. 42(24), 2457-2465 (1988).
-
(1988)
Life Sci.
, vol.42
, Issue.24
, pp. 2457-2465
-
-
Ferretti, C.1
Blengio, M.2
Ghi, P.3
Racca, S.4
Genazzani, E.5
Portaleone, P.6
-
29
-
-
0028277513
-
Tamoxifen decreases drug efflux from liposomes: Relevance to its ability to reverse multidrug resistance in cancer cells?
-
Kayyali R, Marriott C, Wiseman H. Tamoxifen decreases drug efflux from liposomes: relevance to its ability to reverse multidrug resistance in cancer cells? FEBS Lett. 344(2-3), 221-224 (1994).
-
(1994)
FEBS Lett.
, vol.344
, Issue.2-3
, pp. 221-224
-
-
Kayyali, R.1
Marriott, C.2
Wiseman, H.3
-
30
-
-
84862790727
-
A dual-targeting nanocarrier based on poly(amidoamine) dendrimers conjugated with transferrin and tamoxifen for treating brain gliomas
-
Li Y, He H, Jia X, Lu WL, Lou J, Wei Y. A dual-targeting nanocarrier based on poly(amidoamine) dendrimers conjugated with transferrin and tamoxifen for treating brain gliomas. Biomaterials 33(15), 3899-3908 (2012).
-
(2012)
Biomaterials
, vol.33
, Issue.15
, pp. 3899-3908
-
-
Li, Y.1
He, H.2
Jia, X.3
Lu, W.L.4
Lou, J.5
Wei, Y.6
-
31
-
-
0032118268
-
Polyelectrolyte behavior of astramol poly(propyleneimine) dendrimers
-
Kabanov VA, Zezin AB, Rogacheva VB et al. Polyelectrolyte behavior of astramol poly(propyleneimine) dendrimers. Macromolecules 31(15), 5142-5144 (1998).
-
(1998)
Macromolecules
, vol.31
, Issue.15
, pp. 5142-5144
-
-
Kabanov, V.A.1
Zezin, A.B.2
Rogacheva, V.B.3
-
32
-
-
84903531062
-
Transferrin-bearing polypropylenimine dendrimer for targeted gene delivery to the brain
-
Somani S, Blatchford DR, Millington O, Stevenson ML, Dufès C. Transferrin-bearing polypropylenimine dendrimer for targeted gene delivery to the brain. J. Control. Release 188, 78-86 (2014).
-
(2014)
J. Control. Release
, vol.188
, pp. 78-86
-
-
Somani, S.1
Blatchford, D.R.2
Millington, O.3
Stevenson, M.L.4
Dufès, C.5
-
33
-
-
0034836428
-
LRP: A multifunctional scavenger and signaling receptor
-
Herz J, Strickland DK. LRP: a multifunctional scavenger and signaling receptor. J. Clin. Invest. 108(6), 779-784 (2001).
-
(2001)
J. Clin. Invest.
, vol.108
, Issue.6
, pp. 779-784
-
-
Herz, J.1
Strickland, D.K.2
-
34
-
-
0033548463
-
Receptor-mediated transcytosis of lactoferrin through the blood-brain barrier
-
Fillebeen C, Descamps L, Dehouck MP et al. Receptor-mediated transcytosis of lactoferrin through the blood-brain barrier. J. Biol. Chem. 274(11), 7011-7017 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, Issue.11
, pp. 7011-7017
-
-
Fillebeen, C.1
Descamps, L.2
Dehouck, M.P.3
-
35
-
-
35548959221
-
The use of lactoferrin as a ligand for targeting the polyamidoamine-based gene delivery system to the brain
-
Huang R, Ke W, Liu Y, Jiang C, Pei Y. The use of lactoferrin as a ligand for targeting the polyamidoamine-based gene delivery system to the brain. Biomaterials 29(2), 238-246 (2008).
-
(2008)
Biomaterials
, vol.29
, Issue.2
, pp. 238-246
-
-
Huang, R.1
Ke, W.2
Liu, Y.3
Jiang, C.4
Pei, Y.5
-
36
-
-
72049105345
-
Brain-targeting mechanisms of lactoferrin-modified DNA-loaded nanoparticles
-
Huang R, Ke W, Han L et al. Brain-targeting mechanisms of lactoferrin-modified DNA-loaded nanoparticles. J. Cereb. Blood Flow Metab. 29(12), 1914-1923 (2009).
-
(2009)
J. Cereb. Blood Flow Metab.
, vol.29
, Issue.12
, pp. 1914-1923
-
-
Huang, R.1
Ke, W.2
Han, L.3
-
37
-
-
48749095941
-
Involvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector angiopep-2
-
Demeule M, Currie JC, Bertrand Y et al. Involvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector angiopep-2. J. Neurochem. 106(4), 1534-1544 (2008).
-
(2008)
J. Neurochem.
, vol.106
, Issue.4
, pp. 1534-1544
-
-
Demeule, M.1
Currie, J.C.2
Bertrand, Y.3
-
38
-
-
70350200866
-
Gene delivery targeted to the brain using an angiopep-conjugated polyethyleneglycol-modified polyamidoamine dendrimer
-
Ke W, Shao K, Huang R et al. Gene delivery targeted to the brain using an angiopep-conjugated polyethyleneglycol-modified polyamidoamine dendrimer. Biomaterials 30(36), 6976-6985 (2009).
-
(2009)
Biomaterials
, vol.30
, Issue.36
, pp. 6976-6985
-
-
Ke, W.1
Shao, K.2
Huang, R.3
-
39
-
-
84883889734
-
Angiopep-conjugated nanoparticles for targeted long-term gene therapy of Parkinson's disease
-
Huang R, Ma H, Guo Y et al. Angiopep-conjugated nanoparticles for targeted long-term gene therapy of Parkinson's disease. Pharm. Res. 30(10), 2549-2559 (2013).
-
(2013)
Pharm. Res.
, vol.30
, Issue.10
, pp. 2549-2559
-
-
Huang, R.1
Ma, H.2
Guo, Y.3
-
40
-
-
0025123704
-
Brain-type glucose transporter (GLUT-1) is selectively localized to the blood-brain barrier. Studies with quantitative western blotting and in situ hybridization
-
Pardridge WM, Boado RJ, Farrell CR. Brain-type glucose transporter (GLUT-1) is selectively localized to the blood-brain barrier. studies with quantitative western blotting and in situ hybridization. J. Biol. Chem. 265(29), 18035-18040 (1990).
-
(1990)
J. Biol. Chem.
, vol.265
, Issue.29
, pp. 18035-18040
-
-
Pardridge, W.M.1
Boado, R.J.2
Farrell, C.R.3
-
41
-
-
39749200864
-
Methotrexate loaded polyether-copolyester dendrimers for the treatment of gliomas: Enhanced efficacy and intratumoral transport capability
-
Dhanikula RS, Argaw A, Bouchard JF, Hildgen P. Methotrexate loaded polyether-copolyester dendrimers for the treatment of gliomas: enhanced efficacy and intratumoral transport capability. Mol. Pharm. 5(1), 105-116 (2008).
-
(2008)
Mol. Pharm.
, vol.5
, Issue.1
, pp. 105-116
-
-
Dhanikula, R.S.1
Argaw, A.2
Bouchard, J.F.3
Hildgen, P.4
-
43
-
-
67349151056
-
The identification of leptin-derived peptides that are taken up by the brain
-
Barrett GL, Trieu J, Naim T. The identification of leptin-derived peptides that are taken up by the brain. Regul. Pept. 155(1-3), 55-61 (2009).
-
(2009)
Regul. Pept.
, vol.155
, Issue.1-3
, pp. 55-61
-
-
Barrett, G.L.1
Trieu, J.2
Naim, T.3
-
44
-
-
77952289786
-
A leptin derived 30-amino-acid peptide modified pegylated poly-L-lysine dendrigraft for brain targeted gene delivery
-
Liu Y, Li J, Shao K et al. A leptin derived 30-amino-acid peptide modified pegylated poly-L-lysine dendrigraft for brain targeted gene delivery. Biomaterials 31(19), 5246-5257 (2010).
-
(2010)
Biomaterials
, vol.31
, Issue.19
, pp. 5246-5257
-
-
Liu, Y.1
Li, J.2
Shao, K.3
-
45
-
-
79957911957
-
Construction of novel brain-targeting gene delivery system by natural magnetic nanoparticles
-
Han L, Zhang A, Wang H, Pu P, Kang C, Chang J. Construction of novel brain-targeting gene delivery system by natural magnetic nanoparticles. J Appl. Polym. Sci. 121, 3446-3454 (2011).
-
(2011)
J Appl. Polym. Sci.
, vol.121
, pp. 3446-3454
-
-
Han, L.1
Zhang, A.2
Wang, H.3
Pu, P.4
Kang, C.5
Chang, J.6
-
46
-
-
0034595856
-
Transferrin receptor 2-alpha supports cell growth in iron-chelated cultured cells and in vivo
-
Kawabata H, Germain RS, Vuong PT, Nakamaki T, Said JW, Koeffler HP. Transferrin receptor 2-alpha supports cell growth in iron-chelated cultured cells and in vivo. J. Biol. Chem. 275(22), 16618-16625 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.22
, pp. 16618-16625
-
-
Kawabata, H.1
Germain, R.S.2
Vuong, P.T.3
Nakamaki, T.4
Said, J.W.5
Koeffler, H.P.6
-
47
-
-
0025275107
-
Transferrin receptor expression in tumours of the human nervous system: Relation to tumour type, grading and tumour growth fraction
-
Prior R, Reifenberger G, Wechsler W. Transferrin receptor expression in tumours of the human nervous system: relation to tumour type, grading and tumour growth fraction. Virchows Arch. A Pathol Anat. Histopathol. 416(6), 491-496 (1990).
-
(1990)
Virchows Arch. A Pathol Anat. Histopathol.
, vol.416
, Issue.6
, pp. 491-496
-
-
Prior, R.1
Reifenberger, G.2
Wechsler, W.3
-
48
-
-
0022858683
-
A new concept in macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS
-
Maeda H, Matsumura Y. A new concept in macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS. Cancer Res. 46(12 Pt 1), 6387-9392 (1986).
-
(1986)
Cancer Res.
, vol.46
, Issue.12
, pp. 6387-9392
-
-
Maeda, H.1
Matsumura, Y.2
-
49
-
-
25144524987
-
Dendritic supramolecular assemblies for drug delivery
-
Morgan MT, Carnahan MA, Finkelstein S et al. Dendritic supramolecular assemblies for drug delivery. Chem. Commun. 34(14), 4309-4311 (2005).
-
(2005)
Chem. Commun.
, vol.34
, Issue.14
, pp. 4309-4311
-
-
Morgan, M.T.1
Carnahan, M.A.2
Finkelstein, S.3
-
50
-
-
33846213522
-
Dendrimer-encapsulated camptothecins: Increased solubility, cellular uptake, and cellular retention affords enhanced anticancer activity in vitro
-
Morgan MT, Nakanishi Y, Kroll DJ et al. Dendrimer-encapsulated camptothecins: increased solubility, cellular uptake, and cellular retention affords enhanced anticancer activity in vitro. Cancer Res. 66(24), 11913-11921 (2006).
-
(2006)
Cancer Res.
, vol.66
, Issue.24
, pp. 11913-11921
-
-
Morgan, M.T.1
Nakanishi, Y.2
Kroll, D.J.3
-
51
-
-
0033376651
-
Dendrimer-platinate: A novel approach to cancer chemotherapy
-
Malik N, Evagorou EG, Duncan R. Dendrimer-platinate: a novel approach to cancer chemotherapy. Anticancer Drugs 10(8), 767-776 (1999).
-
(1999)
Anticancer Drugs
, vol.10
, Issue.8
, pp. 767-776
-
-
Malik, N.1
Evagorou, E.G.2
Duncan, R.3
-
52
-
-
0033657796
-
Synthesis of polyamidoamine dendrimers having poly(ethylene glycol) grafts and their ability to encapsulate anticancer drugs
-
Kojima C, Kono K, Maruyama K, Takagishi T. Synthesis of polyamidoamine dendrimers having poly(ethylene glycol) grafts and their ability to encapsulate anticancer drugs. Bioconjug. Chem. 11(6), 910-917 (2000).
-
(2000)
Bioconjug. Chem.
, vol.11
, Issue.6
, pp. 910-917
-
-
Kojima, C.1
Kono, K.2
Maruyama, K.3
Takagishi, T.4
-
53
-
-
24144451290
-
Doxorubicin-PAMAM dendrimer complex attached to liposomes: Cytotoxic studies against human cancer cell lines
-
Papagiannaros A, Dimas K, Papaioannou GT, Demetzos C. Doxorubicin-PAMAM dendrimer complex attached to liposomes: cytotoxic studies against human cancer cell lines. Int. J. Pharm. 302(1-2), 29-38 (2005).
-
(2005)
Int. J. Pharm.
, vol.302
, Issue.1-2
, pp. 29-38
-
-
Papagiannaros, A.1
Dimas, K.2
Papaioannou, G.T.3
Demetzos, C.4
-
54
-
-
15244357889
-
Synthesis and evaluation of a star amphiphilic block copolymer from poly(epsilon-caprolactone) and poly(ethylene glycol) as a potential drug delivery carrier
-
Wang F, Bronich TK, Kabanov AV, Rauh RD, Roovers J. Synthesis and evaluation of a star amphiphilic block copolymer from poly(epsilon-caprolactone) and poly(ethylene glycol) as a potential drug delivery carrier. Bioconjug. Chem. 16(2), 397-405 (2005).
-
(2005)
Bioconjug. Chem.
, vol.16
, Issue.2
, pp. 397-405
-
-
Wang, F.1
Bronich, T.K.2
Kabanov, A.V.3
Rauh, R.D.4
Roovers, J.5
-
55
-
-
0037433811
-
A PEGylated dendritic nanoparticulate carrier of fluorouracil
-
Bhadra D, Bhadra S, Jain S, Jain NK. A PEGylated dendritic nanoparticulate carrier of fluorouracil. Int. J. Pharm. 257(1-2), 111-124 (2003).
-
(2003)
Int. J. Pharm.
, vol.257
, Issue.1-2
, pp. 111-124
-
-
Bhadra, D.1
Bhadra, S.2
Jain, S.3
Jain, N.K.4
-
56
-
-
20044396385
-
Reduction of drug toxicity using dendrimers based on melamine
-
Neerman MF, Chen HT, Parrish AR, Simanek EE. Reduction of drug toxicity using dendrimers based on melamine. Mol. Pharm. 1(5), 390-393 (2004).
-
(2004)
Mol. Pharm.
, vol.1
, Issue.5
, pp. 390-393
-
-
Neerman, M.F.1
Chen, H.T.2
Parrish, A.R.3
Simanek, E.E.4
-
57
-
-
33644864871
-
Targeted delivery of methotrexate to epidermal growth factor receptor-positive brain tumors by means of cetuximab (IMC-C225) dendrimer bioconjugates
-
Wu G, Barth RF, Yang WL, Kawabata S, Zhang LW, Green- Church K. Targeted delivery of methotrexate to epidermal growth factor receptor-positive brain tumors by means of cetuximab (IMC-C225) dendrimer bioconjugates. Mol. Cancer Ther. 5(1), 52-59 (2006).
-
(2006)
Mol. Cancer Ther.
, vol.5
, Issue.1
, pp. 52-59
-
-
Wu, G.1
Barth, R.F.2
Yang, W.L.3
Kawabata, S.4
Zhang, L.W.5
Green-Church, K.6
-
58
-
-
9244252033
-
Hydrotropic dendrimers of generations 4 and 5: Synthesis, characterization, and hydrotropic solubilization of paclitaxel
-
Ooya T, Lee J, Park K. Hydrotropic dendrimers of generations 4 and 5: synthesis, characterization, and hydrotropic solubilization of paclitaxel. Bioconjug. Chem. 15(6), 1221-1229 (2004).
-
(2004)
Bioconjug. Chem.
, vol.15
, Issue.6
, pp. 1221-1229
-
-
Ooya, T.1
Lee, J.2
Park, K.3
-
59
-
-
0029815542
-
Dendrimers: Biocompatibility and potential for delivery of anticancer agents
-
Duncan R, Malik N. Dendrimers: biocompatibility and potential for delivery of anticancer agents. Proc. Int. Symp. Control. Release Bioact. Mater. 23, 105-106 (1996).
-
(1996)
Proc. Int. Symp. Control. Release Bioact. Mater.
, vol.23
, pp. 105-106
-
-
Duncan, R.1
Malik, N.2
-
60
-
-
33750936437
-
A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas
-
Lee CC, Gillies ER, Fox ME et al. A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas. Proc. Natl Acad. Sci. USA 103(45), 16649-16654 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.45
, pp. 16649-16654
-
-
Lee, C.C.1
Gillies, E.R.2
Fox, M.E.3
-
61
-
-
20144380223
-
Targeting and inhibition of cell growth by an engineered dendritic nanodevice
-
Thomas TP, Majoros IJ, Kotlyar A et al. Targeting and inhibition of cell growth by an engineered dendritic nanodevice. J. Med. Chem. 48(11), 3729-3735 (2005).
-
(2005)
J. Med. Chem.
, vol.48
, Issue.11
, pp. 3729-3735
-
-
Thomas, T.P.1
Majoros, I.J.2
Kotlyar, A.3
-
62
-
-
0033959448
-
Effective suicide gene therapy in vivo by EBV-based plasmid vector coupled with polyamidoamine dendrimer
-
Maruyama-Tabata H, Harada Y, Matsumura T et al. Effective suicide gene therapy in vivo by EBV-based plasmid vector coupled with polyamidoamine dendrimer. Gene Ther. 7(1), 53-60 (2000).
-
(2000)
Gene Ther.
, vol.7
, Issue.1
, pp. 53-60
-
-
Maruyama-Tabata, H.1
Harada, Y.2
Matsumura, T.3
-
63
-
-
0035181482
-
Tumor targeting and imaging of intraperitoneal tumors by use of antisense oligo- DNA complexed with dendrimers and/or avidin in mice
-
Sato N, Kobayashi H, Saga T et al. Tumor targeting and imaging of intraperitoneal tumors by use of antisense oligo- DNA complexed with dendrimers and/or avidin in mice. Clin. Cancer Res. 7(11), 3606-3612 (2001).
-
(2001)
Clin. Cancer Res.
, vol.7
, Issue.11
, pp. 3606-3612
-
-
Sato, N.1
Kobayashi, H.2
Saga, T.3
-
64
-
-
84874124218
-
Arginine modified PAMAM dendrimer for interferon beta gene delivery to malignant glioma
-
Bai CZ, Choi S, Nam K, An S, Park JS. Arginine modified PAMAM dendrimer for interferon beta gene delivery to malignant glioma. Int. J. Pharm. 445(1-2), 79-87 (2013).
-
(2013)
Int. J. Pharm.
, vol.445
, Issue.1-2
, pp. 79-87
-
-
Bai, C.Z.1
Choi, S.2
Nam, K.3
An, S.4
Park, J.S.5
-
65
-
-
35649024193
-
Importance of size-to-charge ratio in construction of stable and uniform nanoscale RNA/ dendrimer complexes
-
Shen XC, Zhou J, Liu X et al. Importance of size-to-charge ratio in construction of stable and uniform nanoscale RNA/ dendrimer complexes. Org. Biomol. Chem. 5, 3674-3681 (2007).
-
(2007)
Org. Biomol. Chem.
, vol.5
, pp. 3674-3681
-
-
Shen, X.C.1
Zhou, J.2
Liu, X.3
-
66
-
-
84863229706
-
Efficient delivery of sticky siRNA and potent gene silencing in a prostate cancer model using a generation 5 triethanolamine-core PAMAM dendrimer
-
Liu X, Liu C, Laurini E et al. Efficient delivery of sticky siRNA and potent gene silencing in a prostate cancer model using a generation 5 triethanolamine-core PAMAM dendrimer. Mol. Pharm. 9(3), 470-481 (2012).
-
(2012)
Mol. Pharm.
, vol.9
, Issue.3
, pp. 470-481
-
-
Liu, X.1
Liu, C.2
Laurini, E.3
-
67
-
-
78649444101
-
Plasmid pORF-hTRAIL and doxorubicin co-delivery targeting to tumor using peptide-conjugated polyamidoamine dendrimer
-
Han L, Huang R, Li J, Liu S, Huang S, Jiang C. Plasmid pORF-hTRAIL and doxorubicin co-delivery targeting to tumor using peptide-conjugated polyamidoamine dendrimer. Biomaterials 32(4), 1242-1252 (2011).
-
(2011)
Biomaterials
, vol.32
, Issue.4
, pp. 1242-1252
-
-
Han, L.1
Huang, R.2
Li, J.3
Liu, S.4
Huang, S.5
Jiang, C.6
-
68
-
-
79960561767
-
Dual targeting effect of Angiopep-2-modified, DNA-loaded nanoparticles for glioma
-
Huang S, Li J, Han L et al. Dual targeting effect of Angiopep-2-modified, DNA-loaded nanoparticles for glioma. Biomaterials 32(28), 6832-6838 (2011).
-
(2011)
Biomaterials
, vol.32
, Issue.28
, pp. 6832-6838
-
-
Huang, S.1
Li, J.2
Han, L.3
-
69
-
-
77950948806
-
Tat-BMPs-PAMAM conjugates enhance therapeutic effect of small interference RNA on U251 glioma cells in vitro and in vivo
-
Han L, Zhang A, Wang H et al. Tat-BMPs-PAMAM conjugates enhance therapeutic effect of small interference RNA on U251 glioma cells in vitro and in vivo. Hum. Gene Ther. 21(4), 417-426 (2010).
-
(2010)
Hum. Gene Ther.
, vol.21
, Issue.4
, pp. 417-426
-
-
Han, L.1
Zhang, A.2
Wang, H.3
-
70
-
-
70449700090
-
Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery
-
Taratula O, Garbuzenko OB, Kirkpatrick P et al. Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery. J. Control. Release 140(3), 284-293 (2009).
-
(2009)
J. Control. Release
, vol.140
, Issue.3
, pp. 284-293
-
-
Taratula, O.1
Garbuzenko, O.B.2
Kirkpatrick, P.3
-
71
-
-
78650883368
-
Multifunctional nanomedicine platform for cancer specific delivery of siRNA by superparamagnetic iron oxide nanoparticles-dendrimer complexes
-
Taratula O, Garbuzenko O, Savla R, Wang YA, He H, Minko T. Multifunctional nanomedicine platform for cancer specific delivery of siRNA by superparamagnetic iron oxide nanoparticles-dendrimer complexes. Curr. Drug Deliv. 8(1), 59-69 (2011).
-
(2011)
Curr. Drug Deliv.
, vol.8
, Issue.1
, pp. 59-69
-
-
Taratula, O.1
Garbuzenko, O.2
Savla, R.3
Wang, Y.A.4
He, H.5
Minko, T.6
-
72
-
-
24944434257
-
Synthetic anticancer gene medicine exploits intrinsic antitumor activity of cationic vector to cure established tumours
-
Dufès C, Keith WN, Bisland A, Proutski I, Uchegbu IF, Schätzlein AG. Synthetic anticancer gene medicine exploits intrinsic antitumor activity of cationic vector to cure established tumours. Cancer Res. 65(18), 8079-8084 (2005).
-
(2005)
Cancer Res.
, vol.65
, Issue.18
, pp. 8079-8084
-
-
Dufès, C.1
Keith, W.N.2
Bisland, A.3
Proutski, I.4
Uchegbu, I.F.5
Schätzlein, A.G.6
-
74
-
-
77950341675
-
Tumor regression after systemic administration of a novel tumor-targeted gene delivery system carrying a therapeutic plasmid DNA
-
Koppu S, Oh YJ, Edrada-Ebel R et al. Tumor regression after systemic administration of a novel tumor-targeted gene delivery system carrying a therapeutic plasmid DNA. J. Control. Release 143(2), 215-221 (2010).
-
(2010)
J. Control. Release
, vol.143
, Issue.2
, pp. 215-221
-
-
Koppu, S.1
Oh, Y.J.2
Edrada-Ebel, R.3
-
75
-
-
84899861572
-
Therapeutic efficacy of intravenously administered transferrin-conjugated dendriplexes on prostate carcinomas
-
Al Robaian M, Chiam KY, Blatchford DR, Dufès C. Therapeutic efficacy of intravenously administered transferrin-conjugated dendriplexes on prostate carcinomas. Nanomedicine 9(4), 421-434 (2014).
-
(2014)
Nanomedicine
, vol.9
, Issue.4
, pp. 421-434
-
-
Al Robaian, M.1
Chiam, K.Y.2
Blatchford, D.R.3
Dufès, C.4
-
76
-
-
84855966213
-
Tumor regression following intravenous administration of a tumor-targeted p73 gene delivery system
-
Lemarié F, Croft DR, Tate RJ, Ryan KM, Dufès C. Tumor regression following intravenous administration of a tumor-targeted p73 gene delivery system. Biomaterials 33(9), 2701-2709 (2012).
-
(2012)
Biomaterials
, vol.33
, Issue.9
, pp. 2701-2709
-
-
Lemarié, F.1
Croft, D.R.2
Tate, R.J.3
Ryan, K.M.4
Dufès, C.5
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