State-dependent blocker interactions with the CFTR chloride channel: implications for gating the pore

Pflugers Archiv European Journal of Physiology

Volumn 466, Issue 12, 2014, Pages 2243-2255

  Linsdell, Paul ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Chloride channel; Cystic fibrosis transmembrane conductance regulator; Ion channel pore; Open channel block; Site directed mutagenesis; State dependent block

Indexed keywords

ANION; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; VOLTAGE GATED SODIUM CHANNEL BLOCKING AGENT; PLATINUM DERIVATIVE; PROTEIN BINDING;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CHANNEL GATING; CHLORIDE CONDUCTANCE; CONFORMATIONAL TRANSITION; MEMBRANE POTENTIAL; NONHUMAN; PATCH CLAMP TECHNIQUE; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; ROOM TEMPERATURE; VESTIBULE; ANTAGONISTS AND INHIBITORS; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM;

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HEK293 CELLS; HUMANS; ION CHANNEL GATING; PLATINUM COMPOUNDS; PROTEIN BINDING;

EID: 84912047980     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-014-1501-7     Document Type: Article

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