-
1
-
-
33947305641
-
Transporters as channels
-
DOI 10.1146/annurev.physiol.69.031905.164816
-
DeFelice, L. J., and Goswami, T. (2007) Transporters as channels. Annu. Rev. Physiol. 69, 87-112 (Pubitemid 46457637)
-
(2007)
Annual Review of Physiology
, vol.69
, pp. 87-112
-
-
DeFelice, L.J.1
Goswami, T.2
-
2
-
-
70349312287
-
The ATP-binding cassette family: A structural perspective
-
Kos, V., and Ford, R. C. (2009) The ATP-binding cassette family: a structural perspective. Cell Mol. Life Sci. 66, 3111-3126
-
(2009)
Cell Mol. Life Sci.
, vol.66
, pp. 3111-3126
-
-
Kos, V.1
Ford, R.C.2
-
3
-
-
61449341855
-
Review: Structure and mechanism of ATP-binding cassette transporters
-
Locher, K. P. (2009) Review: structure and mechanism of ATP-binding cassette transporters. Phil. Trans. R. Soc. B 364, 239-245
-
(2009)
Phil. Trans. R. Soc. B
, vol.364
, pp. 239-245
-
-
Locher, K.P.1
-
4
-
-
60749083913
-
ABC transporters: The power to change
-
Rees, D. C., Johnson, E., and Lewinson, O. (2009) ABC transporters: the power to change. Nat. Rev. Mol. Cell Biol. 10, 218-227
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 218-227
-
-
Rees, D.C.1
Johnson, E.2
Lewinson, O.3
-
5
-
-
67349185408
-
Ion channels versus ion pumps: The principal difference, in principle
-
Gadsby, D. C. (2009) Ion channels versus ion pumps: the principal difference, in principle. Nat. Rev. Mol. Cell Biol. 10, 344-352
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 344-352
-
-
Gadsby, D.C.1
-
6
-
-
33645307384
-
The ABC protein turned chloride channel whose failure causes cystic fibrosis
-
Gadsby, D. C., Vergani, P., and Csanády, L. (2006) The ABC protein turned chloride channel whose failure causes cystic fibrosis. Nature 440, 477-483
-
(2006)
Nature
, vol.440
, pp. 477-483
-
-
Gadsby, D.C.1
Vergani, P.2
Csanády, L.3
-
7
-
-
65749102092
-
- channel by ATP-driven nucleotide-binding domain dimerisation
-
- channel by ATP-driven nucleotide-binding domain dimerisation. J. Physiol. 587, 2151-2161
-
(2009)
J. Physiol.
, vol.587
, pp. 2151-2161
-
-
Hwang, T.C.1
Sheppard, D.N.2
-
8
-
-
75749112587
-
CFTR: Break a pump, make a channel
-
Miller, C. (2010) CFTR: break a pump, make a channel. Proc. Natl. Acad. Sci. U.S.A. 107, 959-960
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 959-960
-
-
Miller, C.1
-
9
-
-
57649178312
-
Three-dimensional reconstruction of human cystic fibrosis transmembrane conductance regulator chloride channel revealed an ellipsoidal structure with orifices beneath the putative transmembrane domain
-
Mio, K., Ogura, T., Mio, M., Shimizu, H., Hwang, T. C., Sato, C., and Sohma, Y. (2008) Three-dimensional reconstruction of human cystic fibrosis transmembrane conductance regulator chloride channel revealed an ellipsoidal structure with orifices beneath the putative transmembrane domain. J. Biol. Chem. 283, 30300-30310
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 30300-30310
-
-
Mio, K.1
Ogura, T.2
Mio, M.3
Shimizu, H.4
Hwang, T.C.5
Sato, C.6
Sohma, Y.7
-
10
-
-
78649761241
-
Domain location within the cystic fibrosis transmembrane conductance regulator protein investigated by electron microscopy and gold labelling
-
Zhang, L., Aleksandrov, L. A., Riordan, J. R., and Ford, R. C. (2011) Domain location within the cystic fibrosis transmembrane conductance regulator protein investigated by electron microscopy and gold labelling. Biochim. Biophys. Acta 1808, 399-404
-
(2011)
Biochim. Biophys. Acta
, vol.1808
, pp. 399-404
-
-
Zhang, L.1
Aleksandrov, L.A.2
Riordan, J.R.3
Ford, R.C.4
-
11
-
-
82755176172
-
The cystic fibrosis transmembrane conductance regulator (CFTR): Three-dimensional structure and localization of a channel gate
-
Rosenberg, M. F., O'Ryan, L. P., Hughes, G., Zhao, Z., Aleksandrov, L. A., Riordan, J. R., and Ford, R. C. (2011) The cystic fibrosis transmembrane conductance regulator (CFTR): three-dimensional structure and localization of a channel gate. J. Biol. Chem. 286, 42647-42654
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 42647-42654
-
-
Rosenberg, M.F.1
O'Ryan, L.P.2
Hughes, G.3
Zhao, Z.4
Aleksandrov, L.A.5
Riordan, J.R.6
Ford, R.C.7
-
12
-
-
50249090046
-
Atomic model of human cystic fibrosis transmembrane conductance regulator: Membrane-spanning domains and coupling interfaces
-
Mornon, J. P., Lehn, P., and Callebaut, I. (2008) Atomic model of human cystic fibrosis transmembrane conductance regulator: membrane-spanning domains and coupling interfaces. Cell Mol. Life Sci. 65, 2594-2612
-
(2008)
Cell Mol. Life Sci.
, vol.65
, pp. 2594-2612
-
-
Mornon, J.P.1
Lehn, P.2
Callebaut, I.3
-
13
-
-
42149120706
-
Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function
-
DOI 10.1073/pnas.0800254105
-
Serohijos, A. W., Hegedus, T., Aleksandrov, A. A., He, L., Cui, L., Dokholyan, N. V., and Riordan, J. R. (2008) Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function. Proc. Natl. Acad. Sci. U.S.A. 105, 3256-3261 (Pubitemid 351723540)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.9
, pp. 3256-3261
-
-
Serohijos, A.W.R.1
Hegedus, T.2
Aleksandrov, A.A.3
He, L.4
Cui, L.5
Dokholyan, N.V.6
Riordan, J.R.7
-
14
-
-
70350236733
-
Cystic fibrosis transmembrane conductance regulator: Using differential reactivity toward channel-permeant and channel-impermeant thiol-reactive probes to test a molecular model for the pore
-
Alexander, C., Ivetac, A., Liu, X., Norimatsu, Y., Serrano, J. R., Landstrom, A., Sansom, M., and Dawson, D. C. (2009) Cystic fibrosis transmembrane conductance regulator: using differential reactivity toward channel-permeant and channel-impermeant thiol-reactive probes to test a molecular model for the pore. Biochemistry 48, 10078-10088
-
(2009)
Biochemistry
, vol.48
, pp. 10078-10088
-
-
Alexander, C.1
Ivetac, A.2
Liu, X.3
Norimatsu, Y.4
Serrano, J.R.5
Landstrom, A.6
Sansom, M.7
Dawson, D.C.8
-
15
-
-
70349847830
-
Molecular models of the open and closed states of the whole human CFTR protein
-
Mornon, J. P., Lehn, P., and Callebaut, I. (2009) Molecular models of the open and closed states of the whole human CFTR protein. Cell Mol. Life Sci. 66, 3469-3486
-
(2009)
Cell Mol. Life Sci.
, vol.66
, pp. 3469-3486
-
-
Mornon, J.P.1
Lehn, P.2
Callebaut, I.3
-
17
-
-
77957761417
-
Changes in accessibility of cytoplasmic substances to the pore associated with activation of the cystic fibrosis transmembrane conductance regulator chloride channel
-
El Hiani, Y., and Linsdell, P. (2010) Changes in accessibility of cytoplasmic substances to the pore associated with activation of the cystic fibrosis transmembrane conductance regulator chloride channel. J. Biol. Chem. 285, 32126-32140
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 32126-32140
-
-
El Hiani, Y.1
Linsdell, P.2
-
18
-
-
79961146667
-
Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore
-
Wang, W., El Hiani, Y., and Linsdell, P. (2011) Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore. J. Gen. Physiol. 138, 165-178
-
(2011)
J. Gen. Physiol.
, vol.138
, pp. 165-178
-
-
Wang, W.1
El Hiani, Y.2
Linsdell, P.3
-
19
-
-
33750222000
-
In vivo phosphorylation of CFTR promotes formation of a nucleotide-binding domain heterodimer
-
DOI 10.1038/sj.emboj.7601373, PII 7601373
-
Mense, M., Vergani, P., White, D. M., Altberg, G., Nairn, A. C., and Gadsby, D. C. (2006) In vivo phosphorylation of CFTR promotes formation of a nucleotide-binding domain heterodimer. EMBO J. 25, 4728-4739 (Pubitemid 44607019)
-
(2006)
EMBO Journal
, vol.25
, Issue.20
, pp. 4728-4739
-
-
Mense, M.1
Vergani, P.2
White, D.M.3
Altberg, G.4
Nairn, A.C.5
Gadsby, D.C.6
-
20
-
-
70350336877
-
Cysteine-independent inhibition of the CFTR chloride channel by the cysteine-reactive reagent sodium (2-sulphonatoethyl) methanethiosulphonate
-
Li, M. S., Demsey, A. F., Qi, J., and Linsdell, P. (2009) Cysteine-independent inhibition of the CFTR chloride channel by the cysteine-reactive reagent sodium (2-sulphonatoethyl) methanethiosulphonate. Br. J. Pharmacol. 157, 1065-1071
-
(2009)
Br. J. Pharmacol.
, vol.157
, pp. 1065-1071
-
-
Li, M.S.1
Demsey, A.F.2
Qi, J.3
Linsdell, P.4
-
21
-
-
80054724207
-
Functional arrangement of the 12th transmembrane region in the CFTR chloride channel pore based on functional investigation of a cysteine-less CFTR variant
-
Qian, F., El Hiani, Y., and Linsdell, P. (2011) Functional arrangement of the 12th transmembrane region in the CFTR chloride channel pore based on functional investigation of a cysteine-less CFTR variant. Pflügers Arch. 462, 559-571
-
(2011)
Pflügers Arch.
, vol.462
, pp. 559-571
-
-
Qian, F.1
El Hiani, Y.2
Linsdell, P.3
-
22
-
-
84862777795
-
Conformational change opening the CFTR chloride channel pore coupled to ATP-dependent gating
-
Wang, W., and Linsdell, P. (2012) Conformational change opening the CFTR chloride channel pore coupled to ATP-dependent gating. Biochim. Biophys. Acta 1818, 851-860
-
(2012)
Biochim. Biophys. Acta
, vol.1818
, pp. 851-860
-
-
Wang, W.1
Linsdell, P.2
-
23
-
-
80755139374
-
Functional differences in pore properties between wild-type and cysteine-less forms of the CFTR chloride channel
-
Holstead, R. G., Li, M. S., and Linsdell, P. (2011) Functional differences in pore properties between wild-type and cysteine-less forms of the CFTR chloride channel. J. Membr. Biol. 243, 15-23
-
(2011)
J. Membr. Biol.
, vol.243
, pp. 15-23
-
-
Holstead, R.G.1
Li, M.S.2
Linsdell, P.3
-
24
-
-
77649161249
-
Regulation of conductance by the number of fixed positive charges in the intracellular vestibule of the CFTR chloride channel pore
-
Zhou, J. J., Li, M. S., Qi., J., and Linsdell, P. (2010) Regulation of conductance by the number of fixed positive charges in the intracellular vestibule of the CFTR chloride channel pore. J. Gen. Physiol. 135, 229-245
-
(2010)
J. Gen. Physiol.
, vol.135
, pp. 229-245
-
-
Zhou, J.J.1
Li, M.S.2
Qi, J.3
Linsdell, P.4
-
25
-
-
29644442896
-
State-dependent chemical reactivity of an engineered cysteine reveals conformational changes in the outer vestibule of the cystic fibrosis transmembrane conductance regulator
-
DOI 10.1074/jbc.M510242200
-
Zhang, Z. R., Song, B., and McCarty, N. A. (2005) State-dependent chemical reactivity of an engineered cysteine reveals conformational changes in the outer vestibule of the cystic fibrosis transmembrane conductance regulator. J. Biol. Chem. 280, 41997-42003 (Pubitemid 43023168)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.51
, pp. 41997-42003
-
-
Zhang, Z.-R.1
Song, B.2
McCarty, N.A.3
-
26
-
-
41949139811
-
Conformational changes in a pore-lining helix coupled to cystic fibrosis transmembrane conductance regulator channel gating
-
Beck, E. J., Yang, Y., Yaemsiri, S., and Raghuram, V. (2008) Conformational changes in a pore-lining helix coupled to cystic fibrosis transmembrane conductance regulator channel gating. J. Biol. Chem. 283, 4957-4966
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 4957-4966
-
-
Beck, E.J.1
Yang, Y.2
Yaemsiri, S.3
Raghuram, V.4
-
27
-
-
77956237499
-
Dual roles of the sixth transmembrane segment of the CFTR chloride channel in gating and permeation
-
Bai, Y., Li, M., and Hwang, T. C. (2010) Dual roles of the sixth transmembrane segment of the CFTR chloride channel in gating and permeation. J. Gen. Physiol. 136, 293-309
-
(2010)
J. Gen. Physiol.
, vol.136
, pp. 293-309
-
-
Bai, Y.1
Li, M.2
Hwang, T.C.3
-
28
-
-
56649092932
-
Identification of positive charges situated at the outer mouth of the CFTR chloride channel pore
-
Zhou, J. J., Fatehi, M., and Linsdell, P. (2008) Identification of positive charges situated at the outer mouth of the CFTR chloride channel pore. Pflügers Arch 457, 351-360
-
(2008)
Pflügers Arch
, vol.457
, pp. 351-360
-
-
Zhou, J.J.1
Fatehi, M.2
Linsdell, P.3
-
30
-
-
32544435783
-
Mechanism of chloride permeation in the cystic fibrosis transmembrane conductance regulator chloride channel
-
Linsdell, P. (2006) Mechanism of chloride permeation in the cystic fibrosis transmembrane conductance regulator chloride channel. Exp. Physiol. 91, 123-129
-
(2006)
Exp. Physiol.
, vol.91
, pp. 123-129
-
-
Linsdell, P.1
-
31
-
-
80555127440
-
Structural basis for the channel function of a degraded ABC transporter, CFTR (ABCC7)
-
Bai, Y., Li, M., and Hwang, T. C. (2011) Structural basis for the channel function of a degraded ABC transporter, CFTR (ABCC7). J. Gen. Physiol. 138, 495-507
-
(2011)
J. Gen. Physiol.
, vol.138
, pp. 495-507
-
-
Bai, Y.1
Li, M.2
Hwang, T.C.3
-
32
-
-
33846818635
-
On the origin of asymmetric interactions between permeant anions and the cystic fibrosis transmembrane conductance regulator chloride channel pore
-
DOI 10.1529/biophysj.106.095349
-
Fatehi, M., St Aubin, C. N., and Linsdell, P. (2007) On the origin of asymmetric interactions between permeant anions and the cystic fibrosis transmembrane conductance regulator chloride channel pore. Biophys. J. 92, 1241-1253 (Pubitemid 46203185)
-
(2007)
Biophysical Journal
, vol.92
, Issue.4
, pp. 1241-1253
-
-
Fatehi, M.1
St., A.C.N.2
Linsdell, P.3
-
34
-
-
0034785913
-
Identification of a region of strong discrimination in the pore of CFTR
-
McCarty, N. A., and Zhang, Z. R. (2001) Identification of a region of strong discrimination in the pore of CFTR. Am. J. Physiol. Lung Cell. Mol. Physiol. 281, L852-867
-
(2001)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.281
-
-
McCarty, N.A.1
Zhang, Z.R.2
|