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Volumn 287, Issue 13, 2012, Pages 10156-10165

Alternating access to the transmembrane domain of the ATP-binding cassette protein cystic fibrosis transmembrane conductance regulator (ABCC7)

Author keywords

[No Author keywords available]

Indexed keywords

ATP-BINDING CASSETTE; CHANNEL OPENING; CHLORIDE CHANNELS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATORS; EXTRACELLULAR; EXTRACELLULAR SOLUTIONS; MECHANISTIC MODELS; METHANETHIOSULFONATE; NUCLEOTIDE-BINDING DOMAIN; OPEN CHANNELS; PATCH CLAMP RECORDING; PROTEIN FAMILY; TRANS-MEMBRANE DOMAINS; TRANSMEMBRANE REGIONS; TRANSMEMBRANES; TRANSPORT MECHANISM;

EID: 84858968426     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.342972     Document Type: Article
Times cited : (29)

References (34)
  • 1
    • 33947305641 scopus 로고    scopus 로고
    • Transporters as channels
    • DOI 10.1146/annurev.physiol.69.031905.164816
    • DeFelice, L. J., and Goswami, T. (2007) Transporters as channels. Annu. Rev. Physiol. 69, 87-112 (Pubitemid 46457637)
    • (2007) Annual Review of Physiology , vol.69 , pp. 87-112
    • DeFelice, L.J.1    Goswami, T.2
  • 2
    • 70349312287 scopus 로고    scopus 로고
    • The ATP-binding cassette family: A structural perspective
    • Kos, V., and Ford, R. C. (2009) The ATP-binding cassette family: a structural perspective. Cell Mol. Life Sci. 66, 3111-3126
    • (2009) Cell Mol. Life Sci. , vol.66 , pp. 3111-3126
    • Kos, V.1    Ford, R.C.2
  • 3
    • 61449341855 scopus 로고    scopus 로고
    • Review: Structure and mechanism of ATP-binding cassette transporters
    • Locher, K. P. (2009) Review: structure and mechanism of ATP-binding cassette transporters. Phil. Trans. R. Soc. B 364, 239-245
    • (2009) Phil. Trans. R. Soc. B , vol.364 , pp. 239-245
    • Locher, K.P.1
  • 5
    • 67349185408 scopus 로고    scopus 로고
    • Ion channels versus ion pumps: The principal difference, in principle
    • Gadsby, D. C. (2009) Ion channels versus ion pumps: the principal difference, in principle. Nat. Rev. Mol. Cell Biol. 10, 344-352
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 344-352
    • Gadsby, D.C.1
  • 6
    • 33645307384 scopus 로고    scopus 로고
    • The ABC protein turned chloride channel whose failure causes cystic fibrosis
    • Gadsby, D. C., Vergani, P., and Csanády, L. (2006) The ABC protein turned chloride channel whose failure causes cystic fibrosis. Nature 440, 477-483
    • (2006) Nature , vol.440 , pp. 477-483
    • Gadsby, D.C.1    Vergani, P.2    Csanády, L.3
  • 7
    • 65749102092 scopus 로고    scopus 로고
    • - channel by ATP-driven nucleotide-binding domain dimerisation
    • - channel by ATP-driven nucleotide-binding domain dimerisation. J. Physiol. 587, 2151-2161
    • (2009) J. Physiol. , vol.587 , pp. 2151-2161
    • Hwang, T.C.1    Sheppard, D.N.2
  • 8
    • 75749112587 scopus 로고    scopus 로고
    • CFTR: Break a pump, make a channel
    • Miller, C. (2010) CFTR: break a pump, make a channel. Proc. Natl. Acad. Sci. U.S.A. 107, 959-960
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 959-960
    • Miller, C.1
  • 9
    • 57649178312 scopus 로고    scopus 로고
    • Three-dimensional reconstruction of human cystic fibrosis transmembrane conductance regulator chloride channel revealed an ellipsoidal structure with orifices beneath the putative transmembrane domain
    • Mio, K., Ogura, T., Mio, M., Shimizu, H., Hwang, T. C., Sato, C., and Sohma, Y. (2008) Three-dimensional reconstruction of human cystic fibrosis transmembrane conductance regulator chloride channel revealed an ellipsoidal structure with orifices beneath the putative transmembrane domain. J. Biol. Chem. 283, 30300-30310
    • (2008) J. Biol. Chem. , vol.283 , pp. 30300-30310
    • Mio, K.1    Ogura, T.2    Mio, M.3    Shimizu, H.4    Hwang, T.C.5    Sato, C.6    Sohma, Y.7
  • 10
    • 78649761241 scopus 로고    scopus 로고
    • Domain location within the cystic fibrosis transmembrane conductance regulator protein investigated by electron microscopy and gold labelling
    • Zhang, L., Aleksandrov, L. A., Riordan, J. R., and Ford, R. C. (2011) Domain location within the cystic fibrosis transmembrane conductance regulator protein investigated by electron microscopy and gold labelling. Biochim. Biophys. Acta 1808, 399-404
    • (2011) Biochim. Biophys. Acta , vol.1808 , pp. 399-404
    • Zhang, L.1    Aleksandrov, L.A.2    Riordan, J.R.3    Ford, R.C.4
  • 11
    • 82755176172 scopus 로고    scopus 로고
    • The cystic fibrosis transmembrane conductance regulator (CFTR): Three-dimensional structure and localization of a channel gate
    • Rosenberg, M. F., O'Ryan, L. P., Hughes, G., Zhao, Z., Aleksandrov, L. A., Riordan, J. R., and Ford, R. C. (2011) The cystic fibrosis transmembrane conductance regulator (CFTR): three-dimensional structure and localization of a channel gate. J. Biol. Chem. 286, 42647-42654
    • (2011) J. Biol. Chem. , vol.286 , pp. 42647-42654
    • Rosenberg, M.F.1    O'Ryan, L.P.2    Hughes, G.3    Zhao, Z.4    Aleksandrov, L.A.5    Riordan, J.R.6    Ford, R.C.7
  • 12
    • 50249090046 scopus 로고    scopus 로고
    • Atomic model of human cystic fibrosis transmembrane conductance regulator: Membrane-spanning domains and coupling interfaces
    • Mornon, J. P., Lehn, P., and Callebaut, I. (2008) Atomic model of human cystic fibrosis transmembrane conductance regulator: membrane-spanning domains and coupling interfaces. Cell Mol. Life Sci. 65, 2594-2612
    • (2008) Cell Mol. Life Sci. , vol.65 , pp. 2594-2612
    • Mornon, J.P.1    Lehn, P.2    Callebaut, I.3
  • 14
    • 70350236733 scopus 로고    scopus 로고
    • Cystic fibrosis transmembrane conductance regulator: Using differential reactivity toward channel-permeant and channel-impermeant thiol-reactive probes to test a molecular model for the pore
    • Alexander, C., Ivetac, A., Liu, X., Norimatsu, Y., Serrano, J. R., Landstrom, A., Sansom, M., and Dawson, D. C. (2009) Cystic fibrosis transmembrane conductance regulator: using differential reactivity toward channel-permeant and channel-impermeant thiol-reactive probes to test a molecular model for the pore. Biochemistry 48, 10078-10088
    • (2009) Biochemistry , vol.48 , pp. 10078-10088
    • Alexander, C.1    Ivetac, A.2    Liu, X.3    Norimatsu, Y.4    Serrano, J.R.5    Landstrom, A.6    Sansom, M.7    Dawson, D.C.8
  • 15
    • 70349847830 scopus 로고    scopus 로고
    • Molecular models of the open and closed states of the whole human CFTR protein
    • Mornon, J. P., Lehn, P., and Callebaut, I. (2009) Molecular models of the open and closed states of the whole human CFTR protein. Cell Mol. Life Sci. 66, 3469-3486
    • (2009) Cell Mol. Life Sci. , vol.66 , pp. 3469-3486
    • Mornon, J.P.1    Lehn, P.2    Callebaut, I.3
  • 17
    • 77957761417 scopus 로고    scopus 로고
    • Changes in accessibility of cytoplasmic substances to the pore associated with activation of the cystic fibrosis transmembrane conductance regulator chloride channel
    • El Hiani, Y., and Linsdell, P. (2010) Changes in accessibility of cytoplasmic substances to the pore associated with activation of the cystic fibrosis transmembrane conductance regulator chloride channel. J. Biol. Chem. 285, 32126-32140
    • (2010) J. Biol. Chem. , vol.285 , pp. 32126-32140
    • El Hiani, Y.1    Linsdell, P.2
  • 18
    • 79961146667 scopus 로고    scopus 로고
    • Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore
    • Wang, W., El Hiani, Y., and Linsdell, P. (2011) Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore. J. Gen. Physiol. 138, 165-178
    • (2011) J. Gen. Physiol. , vol.138 , pp. 165-178
    • Wang, W.1    El Hiani, Y.2    Linsdell, P.3
  • 19
    • 33750222000 scopus 로고    scopus 로고
    • In vivo phosphorylation of CFTR promotes formation of a nucleotide-binding domain heterodimer
    • DOI 10.1038/sj.emboj.7601373, PII 7601373
    • Mense, M., Vergani, P., White, D. M., Altberg, G., Nairn, A. C., and Gadsby, D. C. (2006) In vivo phosphorylation of CFTR promotes formation of a nucleotide-binding domain heterodimer. EMBO J. 25, 4728-4739 (Pubitemid 44607019)
    • (2006) EMBO Journal , vol.25 , Issue.20 , pp. 4728-4739
    • Mense, M.1    Vergani, P.2    White, D.M.3    Altberg, G.4    Nairn, A.C.5    Gadsby, D.C.6
  • 20
    • 70350336877 scopus 로고    scopus 로고
    • Cysteine-independent inhibition of the CFTR chloride channel by the cysteine-reactive reagent sodium (2-sulphonatoethyl) methanethiosulphonate
    • Li, M. S., Demsey, A. F., Qi, J., and Linsdell, P. (2009) Cysteine-independent inhibition of the CFTR chloride channel by the cysteine-reactive reagent sodium (2-sulphonatoethyl) methanethiosulphonate. Br. J. Pharmacol. 157, 1065-1071
    • (2009) Br. J. Pharmacol. , vol.157 , pp. 1065-1071
    • Li, M.S.1    Demsey, A.F.2    Qi, J.3    Linsdell, P.4
  • 21
    • 80054724207 scopus 로고    scopus 로고
    • Functional arrangement of the 12th transmembrane region in the CFTR chloride channel pore based on functional investigation of a cysteine-less CFTR variant
    • Qian, F., El Hiani, Y., and Linsdell, P. (2011) Functional arrangement of the 12th transmembrane region in the CFTR chloride channel pore based on functional investigation of a cysteine-less CFTR variant. Pflügers Arch. 462, 559-571
    • (2011) Pflügers Arch. , vol.462 , pp. 559-571
    • Qian, F.1    El Hiani, Y.2    Linsdell, P.3
  • 22
    • 84862777795 scopus 로고    scopus 로고
    • Conformational change opening the CFTR chloride channel pore coupled to ATP-dependent gating
    • Wang, W., and Linsdell, P. (2012) Conformational change opening the CFTR chloride channel pore coupled to ATP-dependent gating. Biochim. Biophys. Acta 1818, 851-860
    • (2012) Biochim. Biophys. Acta , vol.1818 , pp. 851-860
    • Wang, W.1    Linsdell, P.2
  • 23
    • 80755139374 scopus 로고    scopus 로고
    • Functional differences in pore properties between wild-type and cysteine-less forms of the CFTR chloride channel
    • Holstead, R. G., Li, M. S., and Linsdell, P. (2011) Functional differences in pore properties between wild-type and cysteine-less forms of the CFTR chloride channel. J. Membr. Biol. 243, 15-23
    • (2011) J. Membr. Biol. , vol.243 , pp. 15-23
    • Holstead, R.G.1    Li, M.S.2    Linsdell, P.3
  • 24
    • 77649161249 scopus 로고    scopus 로고
    • Regulation of conductance by the number of fixed positive charges in the intracellular vestibule of the CFTR chloride channel pore
    • Zhou, J. J., Li, M. S., Qi., J., and Linsdell, P. (2010) Regulation of conductance by the number of fixed positive charges in the intracellular vestibule of the CFTR chloride channel pore. J. Gen. Physiol. 135, 229-245
    • (2010) J. Gen. Physiol. , vol.135 , pp. 229-245
    • Zhou, J.J.1    Li, M.S.2    Qi, J.3    Linsdell, P.4
  • 25
    • 29644442896 scopus 로고    scopus 로고
    • State-dependent chemical reactivity of an engineered cysteine reveals conformational changes in the outer vestibule of the cystic fibrosis transmembrane conductance regulator
    • DOI 10.1074/jbc.M510242200
    • Zhang, Z. R., Song, B., and McCarty, N. A. (2005) State-dependent chemical reactivity of an engineered cysteine reveals conformational changes in the outer vestibule of the cystic fibrosis transmembrane conductance regulator. J. Biol. Chem. 280, 41997-42003 (Pubitemid 43023168)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.51 , pp. 41997-42003
    • Zhang, Z.-R.1    Song, B.2    McCarty, N.A.3
  • 26
    • 41949139811 scopus 로고    scopus 로고
    • Conformational changes in a pore-lining helix coupled to cystic fibrosis transmembrane conductance regulator channel gating
    • Beck, E. J., Yang, Y., Yaemsiri, S., and Raghuram, V. (2008) Conformational changes in a pore-lining helix coupled to cystic fibrosis transmembrane conductance regulator channel gating. J. Biol. Chem. 283, 4957-4966
    • (2008) J. Biol. Chem. , vol.283 , pp. 4957-4966
    • Beck, E.J.1    Yang, Y.2    Yaemsiri, S.3    Raghuram, V.4
  • 27
    • 77956237499 scopus 로고    scopus 로고
    • Dual roles of the sixth transmembrane segment of the CFTR chloride channel in gating and permeation
    • Bai, Y., Li, M., and Hwang, T. C. (2010) Dual roles of the sixth transmembrane segment of the CFTR chloride channel in gating and permeation. J. Gen. Physiol. 136, 293-309
    • (2010) J. Gen. Physiol. , vol.136 , pp. 293-309
    • Bai, Y.1    Li, M.2    Hwang, T.C.3
  • 28
    • 56649092932 scopus 로고    scopus 로고
    • Identification of positive charges situated at the outer mouth of the CFTR chloride channel pore
    • Zhou, J. J., Fatehi, M., and Linsdell, P. (2008) Identification of positive charges situated at the outer mouth of the CFTR chloride channel pore. Pflügers Arch 457, 351-360
    • (2008) Pflügers Arch , vol.457 , pp. 351-360
    • Zhou, J.J.1    Fatehi, M.2    Linsdell, P.3
  • 30
    • 32544435783 scopus 로고    scopus 로고
    • Mechanism of chloride permeation in the cystic fibrosis transmembrane conductance regulator chloride channel
    • Linsdell, P. (2006) Mechanism of chloride permeation in the cystic fibrosis transmembrane conductance regulator chloride channel. Exp. Physiol. 91, 123-129
    • (2006) Exp. Physiol. , vol.91 , pp. 123-129
    • Linsdell, P.1
  • 31
    • 80555127440 scopus 로고    scopus 로고
    • Structural basis for the channel function of a degraded ABC transporter, CFTR (ABCC7)
    • Bai, Y., Li, M., and Hwang, T. C. (2011) Structural basis for the channel function of a degraded ABC transporter, CFTR (ABCC7). J. Gen. Physiol. 138, 495-507
    • (2011) J. Gen. Physiol. , vol.138 , pp. 495-507
    • Bai, Y.1    Li, M.2    Hwang, T.C.3
  • 32
    • 33846818635 scopus 로고    scopus 로고
    • On the origin of asymmetric interactions between permeant anions and the cystic fibrosis transmembrane conductance regulator chloride channel pore
    • DOI 10.1529/biophysj.106.095349
    • Fatehi, M., St Aubin, C. N., and Linsdell, P. (2007) On the origin of asymmetric interactions between permeant anions and the cystic fibrosis transmembrane conductance regulator chloride channel pore. Biophys. J. 92, 1241-1253 (Pubitemid 46203185)
    • (2007) Biophysical Journal , vol.92 , Issue.4 , pp. 1241-1253
    • Fatehi, M.1    St., A.C.N.2    Linsdell, P.3
  • 34
    • 0034785913 scopus 로고    scopus 로고
    • Identification of a region of strong discrimination in the pore of CFTR
    • McCarty, N. A., and Zhang, Z. R. (2001) Identification of a region of strong discrimination in the pore of CFTR. Am. J. Physiol. Lung Cell. Mol. Physiol. 281, L852-867
    • (2001) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.281
    • McCarty, N.A.1    Zhang, Z.R.2


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