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Volumn 93, Issue 11, 2014, Pages 1099-1108

Genetic, nongenetic and epigenetic risk determinants in developmental programming of type 2 diabetes

Author keywords

epigenetics; Fetal programming; genetics; gestational diabetes; low birthweight; twins

Indexed keywords

GLUCOSE; INSULIN;

EID: 84912037167     PISSN: 00016349     EISSN: 16000412     Source Type: Journal    
DOI: 10.1111/aogs.12494     Document Type: Review
Times cited : (51)

References (61)
  • 1
    • 2342466734 scopus 로고    scopus 로고
    • Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
    • Wild S, Roglic G, Green A, Sicree R, King H,. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care. 2004; 27: 1047-53.
    • (2004) Diabetes Care , vol.27 , pp. 1047-1053
    • Wild, S.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 2
    • 64649104158 scopus 로고    scopus 로고
    • From the triumvirate to the ominous octet: A new paradigm for the treatment of type 2 diabetes mellitus
    • DeFronzo RA,. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus. Diabetes. 2009; 58: 773-95.
    • (2009) Diabetes , vol.58 , pp. 773-795
    • Defronzo, R.A.1
  • 3
    • 0026008824 scopus 로고
    • Fetal and infant growth and impaired glucose tolerance at age 64
    • Hales CN, Barker DJ, Clark PM, Cox LJ, Fall C, Osmond C, et al. Fetal and infant growth and impaired glucose tolerance at age 64. BMJ. 1991; 303: 1019-22.
    • (1991) BMJ , vol.303 , pp. 1019-1022
    • Hales, C.N.1    Barker, D.J.2    Clark, P.M.3    Cox, L.J.4    Fall, C.5    Osmond, C.6
  • 4
    • 0027529974 scopus 로고
    • Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): Relation to reduced fetal growth
    • Barker DJ, Hales CN, Fall CH, Osmond C, Phipps K, Clark PM,. Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth. Diabetolgia. 1993; 36: 62-7.
    • (1993) Diabetolgia , vol.36 , pp. 62-67
    • Barker, D.J.1    Hales, C.N.2    Fall, C.H.3    Osmond, C.4    Phipps, K.5    Clark, P.M.6
  • 6
    • 0036227764 scopus 로고    scopus 로고
    • Early differential defects of insulin secretion and action in 19-year-old caucasian men who had low birthweight
    • Jensen CB, Storgaard H, Dela F, Holst JJ, Madsbad S, Vaag AA,. Early differential defects of insulin secretion and action in 19-year-old caucasian men who had low birthweight. Diabetes. 2002; 51: 1271-80.
    • (2002) Diabetes , vol.51 , pp. 1271-1280
    • Jensen, C.B.1    Storgaard, H.2    Dela, F.3    Holst, J.J.4    Madsbad, S.5    Vaag, A.A.6
  • 7
    • 53749088978 scopus 로고    scopus 로고
    • Mitochondrial function in skeletal muscle is normal and unrelated to insulin action in young men born with low birthweight
    • Brøns C1, Jensen CB, Storgaard H, Alibegovic A, Jacobsen S, Nilsson E, et al. Mitochondrial function in skeletal muscle is normal and unrelated to insulin action in young men born with low birthweight. J Clin Endocrinol Metab. 2008; 93: 3885-92.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 3885-3892
    • Brøns, C.1    Jensen, C.B.2    Storgaard, H.3    Alibegovic, A.4    Jacobsen, S.5    Nilsson, E.6
  • 8
    • 83155177157 scopus 로고    scopus 로고
    • Disassociation of liver and muscle insulin resistance from ectopic lipid accumulation in low-birth-weight individuals
    • Dufour S, Petersen KF,. Disassociation of liver and muscle insulin resistance from ectopic lipid accumulation in low-birth-weight individuals. J Clin Endocrinol Metab. 2011; 96: 3873-80.
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 3873-3880
    • Dufour, S.1    Petersen, K.F.2
  • 10
    • 0030463887 scopus 로고    scopus 로고
    • Altered muscle insulin sensitivity in the male offspring of protein-malnourished rats
    • Ozanne SE, Wang CL, Coleman N, Smith GD,. Altered muscle insulin sensitivity in the male offspring of protein-malnourished rats. Am J Physiol Endocrinol Metab. 1996; 271: E1128-34.
    • (1996) Am J Physiol Endocrinol Metab , vol.271 , pp. E1128-E1134
    • Ozanne, S.E.1    Wang, C.L.2    Coleman, N.3    Smith, G.D.4
  • 11
    • 0038137103 scopus 로고    scopus 로고
    • Early growth restriction leads to down regulation of protein kinase C zeta and insulin resistance in skeletal muscle
    • Ozanne SE, Olsen GS, Hansen LL, Tingey KL, Nave BT, Wang CL, et al. Early growth restriction leads to down regulation of protein kinase C zeta and insulin resistance in skeletal muscle. J Endocrinol. 2003; 177: 235-41.
    • (2003) J Endocrinol , vol.177 , pp. 235-241
    • Ozanne, S.E.1    Olsen, G.S.2    Hansen, L.L.3    Tingey, K.L.4    Nave, B.T.5    Wang, C.L.6
  • 13
    • 0035489035 scopus 로고    scopus 로고
    • Intrauterine growth retardation leads to the development of type 2 diabetes in the rat
    • Simmons RA, Templeton LJ, Gertz SJ,. Intrauterine growth retardation leads to the development of type 2 diabetes in the rat. Diabetes. 2001; 50: 2279-86.
    • (2001) Diabetes , vol.50 , pp. 2279-2286
    • Simmons, R.A.1    Templeton, L.J.2    Gertz, S.J.3
  • 15
    • 0032953097 scopus 로고    scopus 로고
    • Heritability of Type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance - A population-based twin study
    • Poulsen P, Ohm Kyvik K, Vaag A, Beck-Nielsen H,. Heritability of Type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance-a population-based twin study. Diabetologia. 1999; 42: 139-45.
    • (1999) Diabetologia , vol.42 , pp. 139-145
    • Poulsen, P.1    Ohm, K.K.2    Vaag, A.3    Beck-Nielsen, H.4
  • 16
    • 0030980023 scopus 로고    scopus 로고
    • Low birthweight is associated with NIDDM in discordant monozygotic and dizygotic twin pairs
    • Poulsen P, Vaag AA, Kyvik KO, Moller JD, Beck-Nielsen H,. Low birthweight is associated with NIDDM in discordant monozygotic and dizygotic twin pairs. Diabetologia. 1997; 40: 439-46.
    • (1997) Diabetologia , vol.40 , pp. 439-446
    • Poulsen, P.1    Vaag, A.A.2    Kyvik, K.O.3    Moller, J.D.4    Beck-Nielsen, H.5
  • 17
    • 0033594787 scopus 로고    scopus 로고
    • The fetal insulin hypothesis: An alternative explanation of the association of low birthweight with diabetes and vascular disease
    • Hattersley AT, Tooke JE,. The fetal insulin hypothesis: an alternative explanation of the association of low birthweight with diabetes and vascular disease. Lancet. 1999; 353: 1789-92.
    • (1999) Lancet , vol.353 , pp. 1789-1792
    • Hattersley, A.T.1    Tooke, J.E.2
  • 18
    • 34347224411 scopus 로고    scopus 로고
    • Birthweight is nongenetically associated with glucose intolerance in elderly twins, independent of adult obesity
    • Grunnet L, Vielwerth S, Vaag A, Poulsen P,. Birthweight is nongenetically associated with glucose intolerance in elderly twins, independent of adult obesity. J Intern Med. 2007; 262: 96-103.
    • (2007) J Intern Med , vol.262 , pp. 96-103
    • Grunnet, L.1    Vielwerth, S.2    Vaag, A.3    Poulsen, P.4
  • 19
  • 23
    • 79960926276 scopus 로고    scopus 로고
    • No evidence of a higher 10 year period prevalence of diabetes among 77,885 twins compared with 215,264 singletons from the Danish birth cohorts 1910-1989
    • Petersen I, Nielsen MM, Beck-Nielsen H, Christensen K,. No evidence of a higher 10 year period prevalence of diabetes among 77,885 twins compared with 215,264 singletons from the Danish birth cohorts 1910-1989. Diabetologia. 2011; 54: 2016-24.
    • (2011) Diabetologia , vol.54 , pp. 2016-2024
    • Petersen, I.1    Nielsen, M.M.2    Beck-Nielsen, H.3    Christensen, K.4
  • 24
    • 84874966710 scopus 로고    scopus 로고
    • The genetics of type 2 diabetes and its clinical relevance
    • Pal A, McCarthy MI,. The genetics of type 2 diabetes and its clinical relevance. Clin Genet. 2013; 83: 297-306.
    • (2013) Clin Genet , vol.83 , pp. 297-306
    • Pal, A.1    McCarthy, M.I.2
  • 25
    • 84868337361 scopus 로고    scopus 로고
    • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
    • Morris AP, Voight BF, Teslovich TM, Ferreira T, Segrè AV, Steinthorsdottir V, et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet. 2012; 44: 981-90.
    • (2012) Nat Genet , vol.44 , pp. 981-990
    • Morris, A.P.1    Voight, B.F.2    Teslovich, T.M.3    Ferreira, T.4    Segrè, A.V.5    Steinthorsdottir, V.6
  • 26
    • 77955558577 scopus 로고    scopus 로고
    • Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight
    • Andersson EA, Pilgaard K, Pisinger C, Harder MN, Grarup N, Faerch K, et al. Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight. Diabetologia. 2010; 53: 1908-16.
    • (2010) Diabetologia , vol.53 , pp. 1908-1916
    • Andersson, E.A.1    Pilgaard, K.2    Pisinger, C.3    Harder, M.N.4    Grarup, N.5    Faerch, K.6
  • 27
    • 84871987100 scopus 로고    scopus 로고
    • New loci associated with birthweight identify genetic links between intrauterine growth and adult height and metabolism
    • Horikoshi M1, Yaghootkar H, Mook-Kanamori DO, Sovio U, Taal HR, Hennig BJ, et al. New loci associated with birthweight identify genetic links between intrauterine growth and adult height and metabolism. Nat Genet. 2012; 45: 76-82.
    • (2012) Nat Genet , vol.45 , pp. 76-82
    • Horikoshi, M.1    Yaghootkar, H.2    Mook-Kanamori, D.O.3    Sovio, U.4    Taal, H.R.5    Hennig, B.J.6
  • 28
    • 34247126988 scopus 로고    scopus 로고
    • Experimental IUGR and later diabetes
    • Martin-Gronert MS, Ozanne SE,. Experimental IUGR and later diabetes. J Intern Med. 2007; 261: 437-52.
    • (2007) J Intern Med , vol.261 , pp. 437-452
    • Martin-Gronert, M.S.1    Ozanne, S.E.2
  • 29
    • 0017305263 scopus 로고
    • Obesity in young men after famine exposure in utero and early infancy
    • Ravelli G, Stein ZA, Susser MW,. Obesity in young men after famine exposure in utero and early infancy. N Engl J Med. 1976; 295: 349-53.
    • (1976) N Engl J Med , vol.295 , pp. 349-353
    • Ravelli, G.1    Stein, Z.A.2    Susser, M.W.3
  • 30
    • 77957591910 scopus 로고    scopus 로고
    • Exposure to the Chinese famine in early life and the risk of hyperglycemia and type 2 diabetes in adulthood
    • Li Y, He Y, Qi L, Jaddoe VW, Feskens EJ, Yang X, et al. Exposure to the Chinese famine in early life and the risk of hyperglycemia and type 2 diabetes in adulthood. Diabetes. 2010; 59: 2400-2406.
    • (2010) Diabetes , vol.59 , pp. 2400-2406
    • Li, Y.1    He, Y.2    Qi, L.3    Jaddoe, V.W.4    Feskens, E.J.5    Yang, X.6
  • 31
    • 0030704615 scopus 로고    scopus 로고
    • Does malnutrition in utero determine diabetes and coronary heart disease in adulthood? Results from the Leningrad siege study, a cross sectional study
    • Stanner SA, Bulmer K, Andrès C, Lantseva OE, Borodina V, Poteen VV, et al. Does malnutrition in utero determine diabetes and coronary heart disease in adulthood? Results from the Leningrad siege study, a cross sectional study. BMJ. 1997; 315: 1342-8.
    • (1997) BMJ , vol.315 , pp. 1342-1348
    • Stanner, S.A.1    Bulmer, K.2    Andrès, C.3    Lantseva, O.E.4    Borodina, V.5    Poteen, V.V.6
  • 32
    • 48149113970 scopus 로고    scopus 로고
    • The effect of birthweight upon insulin resistance and associated cardiovascular risk factors in adolescence is not explained by fetal growth velocity in the third trimester as measured by repeated ultrasound fetometry
    • Vielwerth SE1, Jensen RB, Larsen T, Holst KK, Mølgaard C, Greisen G, et al. The effect of birthweight upon insulin resistance and associated cardiovascular risk factors in adolescence is not explained by fetal growth velocity in the third trimester as measured by repeated ultrasound fetometry. Diabetologia. 2008; 51: 1483-92.
    • (2008) Diabetologia , vol.51 , pp. 1483-1492
    • Vielwerth, S.1    Jensen, R.B.2    Larsen, T.3    Holst, K.K.4    Mølgaard, C.5    Greisen, G.6
  • 34
    • 84878599173 scopus 로고    scopus 로고
    • Dietary glycemic index during pregnancy is associated with biomarkers of the metabolic syndrome in offspring at age 20 years
    • Danielsen I, Granström C, Haldorsson T, Rytter D, Hammer Bech B, Henriksen TB, et al. Dietary glycemic index during pregnancy is associated with biomarkers of the metabolic syndrome in offspring at age 20 years. PLoS ONE 2013; 8: e64887.
    • (2013) PLoS ONE , vol.8 , pp. e64887
    • Danielsen, I.1    Granström, C.2    Haldorsson, T.3    Rytter, D.4    Hammer Bech, B.5    Henriksen, T.B.6
  • 35
    • 76949132038 scopus 로고
    • Diabetes and pregnancy; Blood sugar of newborn infants during fasting and glucose administration
    • Pedersen J,. Diabetes and pregnancy; blood sugar of newborn infants during fasting and glucose administration. Nord Med. 1952; 47: 1049.
    • (1952) Nord Med , vol.47 , pp. 1049
    • Pedersen, J.1
  • 36
    • 84879308759 scopus 로고    scopus 로고
    • Lifestyle and nutritional imbalances associated with Western diseases: Causes and consequences of chronic systemic low-grade inflammation in an evolutionary context
    • Ruiz-Nunez B, Pruimboom L, Dijck-Brouwer DA, Muskiet FA,. Lifestyle and nutritional imbalances associated with Western diseases: causes and consequences of chronic systemic low-grade inflammation in an evolutionary context. J Nutr Biochem. 2013; 24: 1183-201.
    • (2013) J Nutr Biochem , vol.24 , pp. 1183-1201
    • Ruiz-Nunez, B.1    Pruimboom, L.2    Dijck-Brouwer, D.A.3    Muskiet, F.A.4
  • 37
    • 84899970640 scopus 로고    scopus 로고
    • Subclinical inflammation during third trimester of pregnancy was not associated with markers of the metabolic syndrome in young adult offspring
    • Danielsen I, Granström C, Rytter D, Halldorsson TI, Bech BH, Henriksen TB, et al. Subclinical inflammation during third trimester of pregnancy was not associated with markers of the metabolic syndrome in young adult offspring. Obesity (Silver Spring). 2014; 22: 1351-8.
    • (2014) Obesity (Silver Spring) , vol.22 , pp. 1351-1358
    • Danielsen, I.1    Granström, C.2    Rytter, D.3    Halldorsson, T.I.4    Bech, B.H.5    Henriksen, T.B.6
  • 38
    • 84885378942 scopus 로고    scopus 로고
    • Does physical activity during pregnancy adversely influence markers of the metabolic syndrome in adult offspring? A prospective study over two decades
    • Danielsen I, Granström C, Rytter D, Hammer Bech B, Brink Henriksen T, Vaag AA, et al. Does physical activity during pregnancy adversely influence markers of the metabolic syndrome in adult offspring? A prospective study over two decades. J Epidemiol Community Health. 2013; 67: 648-54.
    • (2013) J Epidemiol Community Health , vol.67 , pp. 648-654
    • Danielsen, I.1    Granström, C.2    Rytter, D.3    Hammer Bech, B.4    Brink Henriksen, T.5    Vaag, A.A.6
  • 39
    • 1042279542 scopus 로고    scopus 로고
    • Gestational diabetes mellitus
    • American Diabetes Association
    • American Diabetes Association. Gestational diabetes mellitus. Diabetes Care. 2004; 27 (Suppl 1): S88-90.
    • (2004) Diabetes Care , vol.27 , pp. S88-S90
  • 40
    • 0036781530 scopus 로고    scopus 로고
    • Gestational diabetes and the incidence of type 2 diabetes: A systematic review
    • Kim C, Newton KM, Knopp RH,. Gestational diabetes and the incidence of type 2 diabetes: a systematic review. Diabetes Care. 2002; 25: 1862-8.
    • (2002) Diabetes Care , vol.25 , pp. 1862-1868
    • Kim, C.1    Newton, K.M.2    Knopp, R.H.3
  • 41
    • 48349118873 scopus 로고    scopus 로고
    • Risk of development of diabetes mellitus after diagnosis of gestational diabetes
    • Feig DS, Zinman B, Wang X, Hux JE,. Risk of development of diabetes mellitus after diagnosis of gestational diabetes. CMAJ. 2008; 179: 229-34.
    • (2008) CMAJ , vol.179 , pp. 229-234
    • Feig, D.S.1    Zinman, B.2    Wang, X.3    Hux, J.E.4
  • 42
    • 34147099693 scopus 로고    scopus 로고
    • Gestational diabetes mellitus: Clinical predictors and long-term risk of developing type 2 diabetes: A retrospective cohort study using survival analysis
    • Lee AJ, Hiscock RJ, Wein P, Walker SP, Permezel M,. Gestational diabetes mellitus: clinical predictors and long-term risk of developing type 2 diabetes: a retrospective cohort study using survival analysis. Diabetes Care. 2007; 30: 878-83.
    • (2007) Diabetes Care , vol.30 , pp. 878-883
    • Lee, A.J.1    Hiscock, R.J.2    Wein, P.3    Walker, S.P.4    Permezel, M.5
  • 43
    • 77958187116 scopus 로고    scopus 로고
    • Prevalence and predictors of overweight and insulin resistance in offspring of mothers with gestational diabetes mellitus
    • Boerschmann H, Pfluger M, Henneberger L, Ziegler AG, Hummel S,. Prevalence and predictors of overweight and insulin resistance in offspring of mothers with gestational diabetes mellitus. Diabetes Care. 2010; 33: 1845-9.
    • (2010) Diabetes Care , vol.33 , pp. 1845-1849
    • Boerschmann, H.1    Pfluger, M.2    Henneberger, L.3    Ziegler, A.G.4    Hummel, S.5
  • 44
    • 43249096940 scopus 로고    scopus 로고
    • Hyperglycemia and adverse pregnancy outcomes
    • HAPO Study Cooperative Research Group
    • HAPO Study Cooperative Research Group, Metzger BE, Lowe LP, Dyer AR, Trimble ER, Chaovarindr U, et al. Hyperglycemia and adverse pregnancy outcomes. N Engl J Med. 2008; 358: 1991-2002.
    • (2008) N Engl J Med , vol.358 , pp. 1991-2002
    • Metzger, B.E.1    Lowe, L.P.2    Dyer, A.R.3    Trimble, E.R.4    Chaovarindr, U.5
  • 45
    • 38949211488 scopus 로고    scopus 로고
    • High prevalence of type 2 diabetes and pre-diabetes in adult offspring of women with gestational diabetes mellitus or type 1 diabetes: The role of intrauterine hyperglycemia
    • Clausen TD, Mathiesen ER, Hansen T, Pedersen O, Jensen DM, Lauenborg J, et al. High prevalence of type 2 diabetes and pre-diabetes in adult offspring of women with gestational diabetes mellitus or type 1 diabetes: the role of intrauterine hyperglycemia. Diabetes Care. 2008; 31: 340-6.
    • (2008) Diabetes Care , vol.31 , pp. 340-346
    • Clausen, T.D.1    Mathiesen, E.R.2    Hansen, T.3    Pedersen, O.4    Jensen, D.M.5    Lauenborg, J.6
  • 46
    • 67650254297 scopus 로고    scopus 로고
    • Overweight and the metabolic syndrome in adult offspring of women with diet-treated gestational diabetes mellitus or type 1 diabetes
    • Clausen TD, Mathiesen ER, Hansen T, Pedersen O, Jensen DM, Lauenborg J, et al. Overweight and the metabolic syndrome in adult offspring of women with diet-treated gestational diabetes mellitus or type 1 diabetes. J Clin Endocrinol Metab. 2009; 94: 2464-70.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 2464-2470
    • Clausen, T.D.1    Mathiesen, E.R.2    Hansen, T.3    Pedersen, O.4    Jensen, D.M.5    Lauenborg, J.6
  • 47
    • 0036319367 scopus 로고    scopus 로고
    • Gestational diabetes leads to the development of diabetes in adulthood in the rat
    • Boloker J, Gertz SJ, Simmons RA,. Gestational diabetes leads to the development of diabetes in adulthood in the rat. Diabetes. 2002; 51: 1499-506.
    • (2002) Diabetes , vol.51 , pp. 1499-1506
    • Boloker, J.1    Gertz, S.J.2    Simmons, R.A.3
  • 48
    • 84859049080 scopus 로고    scopus 로고
    • Women born preterm or with inappropriate weight for gestational age are at risk of subsequent gestational diabetes and pre-eclampsia
    • Rogvi R, Forman JL, Damm P, Greisen G,. Women born preterm or with inappropriate weight for gestational age are at risk of subsequent gestational diabetes and pre-eclampsia. PLoS ONE. 2012; 7: e34001.
    • (2012) PLoS ONE , vol.7 , pp. e34001
    • Rogvi, R.1    Forman, J.L.2    Damm, P.3    Greisen, G.4
  • 49
    • 59349119854 scopus 로고    scopus 로고
    • Nutrient-mediated teratogenesis and fuel-mediated teratogenesis: Two pathways of intrauterine programming of diabetes
    • Yajnik CS,. Nutrient-mediated teratogenesis and fuel-mediated teratogenesis: two pathways of intrauterine programming of diabetes. Int J Gynaecol Obstet. 2009; 104 (Suppl 1): S27-31.
    • (2009) Int J Gynaecol Obstet , vol.104 , pp. S27-S31
    • Yajnik, C.S.1
  • 50
    • 45549097738 scopus 로고    scopus 로고
    • Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1
    • Park JH, Stoffers DA, Nicholls RD, Simmons RA,. Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1. J Clin Invest. 2008; 118: 2316-24.
    • (2008) J Clin Invest , vol.118 , pp. 2316-2324
    • Park, J.H.1    Stoffers, D.A.2    Nicholls, R.D.3    Simmons, R.A.4
  • 51
    • 77954523386 scopus 로고    scopus 로고
    • Deoxyribonucleic acid methylation and gene expression of PPARGC1A in human muscle is influenced by high-fat overfeeding in a birth-weight-dependent manner
    • Brøns C, Jacobsen S, Nilsson E, Rönn T, Jensen CB, Storgaard H, et al. Deoxyribonucleic acid methylation and gene expression of PPARGC1A in human muscle is influenced by high-fat overfeeding in a birth-weight-dependent manner. J Clin Endocrinol Metab. 2010; 95: 3048-56.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 3048-3056
    • Brøns, C.1    Jacobsen, S.2    Nilsson, E.3    Rönn, T.4    Jensen, C.B.5    Storgaard, H.6
  • 52
    • 84892680128 scopus 로고    scopus 로고
    • PPARGC1A DNA methylation in subcutaneous adipose tissue in low birthweight subjects - Impact of 5 days of high-fat overfeeding
    • Gillberg L, Jacobsen SC, Ronn T, Brons C, Vaag A,. PPARGC1A DNA methylation in subcutaneous adipose tissue in low birthweight subjects-impact of 5 days of high-fat overfeeding. Metabolism. 2014; 63: 263-71.
    • (2014) Metabolism , vol.63 , pp. 263-271
    • Gillberg, L.1    Jacobsen, S.C.2    Ronn, T.3    Brons, C.4    Vaag, A.5
  • 53
    • 84868211134 scopus 로고    scopus 로고
    • Effects of short-term high-fat overfeeding on genome-wide DNA methylation in the skeletal muscle of healthy young men
    • Jacobsen SC, Brøns C, Bork-Jensen J, Ribel-Madsen R, Yang B, Lara E, et al. Effects of short-term high-fat overfeeding on genome-wide DNA methylation in the skeletal muscle of healthy young men. Diabetologia. 2012; 55: 3341-9.
    • (2012) Diabetologia , vol.55 , pp. 3341-3349
    • Jacobsen, S.C.1    Brøns, C.2    Bork-Jensen, J.3    Ribel-Madsen, R.4    Yang, B.5    Lara, E.6
  • 54
    • 84901188568 scopus 로고    scopus 로고
    • Young men with low birthweight exhibit decreased plasticity of genome-wide muscle DNA methylation by high-fat overfeeding
    • Jacobsen SC, Gillberg L, Bork-Jensen J, Ribel-Madsen R, Lara E, Calvanese V, et al. Young men with low birthweight exhibit decreased plasticity of genome-wide muscle DNA methylation by high-fat overfeeding. Diabetologia. 2014; 57: 1154-8.
    • (2014) Diabetologia , vol.57 , pp. 1154-1158
    • Jacobsen, S.C.1    Gillberg, L.2    Bork-Jensen, J.3    Ribel-Madsen, R.4    Lara, E.5    Calvanese, V.6
  • 55
    • 84891779946 scopus 로고    scopus 로고
    • Impaired leptin gene expression and release in cultured preadipocytes isolated from individuals born with low birthweight
    • Schultz NS, Broholm C, Gillberg L, Mortensen B, Jørgensen SW, Schultz HS, et al. Impaired leptin gene expression and release in cultured preadipocytes isolated from individuals born with low birthweight. Diabetes. 2014; 63: 111-21.
    • (2014) Diabetes , vol.63 , pp. 111-121
    • Schultz, N.S.1    Broholm, C.2    Gillberg, L.3    Mortensen, B.4    Jørgensen, S.W.5    Schultz, H.S.6
  • 59
    • 84893499767 scopus 로고    scopus 로고
    • Exposure to maternal diabetes in utero and DNA methylation patterns in the offspring
    • West NA, Kechris K, Dabelea D,. Exposure to maternal diabetes in utero and DNA methylation patterns in the offspring. Immunometabolism. 2013; 1: 1-9.
    • (2013) Immunometabolism , vol.1 , pp. 1-9
    • West, N.A.1    Kechris, K.2    Dabelea, D.3
  • 60
    • 84890267386 scopus 로고    scopus 로고
    • Global methylation in the placenta and umbilical cord blood from pregnancies with maternal gestational diabetes, preeclampsia, and obesity
    • Nomura Y, Lambertini L, Rialdi A, Lee M, Mystal EY, Grabie M, et al. Global methylation in the placenta and umbilical cord blood from pregnancies with maternal gestational diabetes, preeclampsia, and obesity. Reprod Sci. 2014; 21: 131-7.
    • (2014) Reprod Sci , vol.21 , pp. 131-137
    • Nomura, Y.1    Lambertini, L.2    Rialdi, A.3    Lee, M.4    Mystal, E.Y.5    Grabie, M.6
  • 61
    • 84875457147 scopus 로고    scopus 로고
    • Metabolic programming of MEST DNA methylation by intrauterine exposure to gestational diabetes mellitus
    • El Hajj N, Pliushch G, Schneider E, Dittrich M, Müller T, Korenkov M, et al. Metabolic programming of MEST DNA methylation by intrauterine exposure to gestational diabetes mellitus. Diabetes. 2013; 62: 1320-8.
    • (2013) Diabetes , vol.62 , pp. 1320-1328
    • El Hajj, N.1    Pliushch, G.2    Schneider, E.3    Dittrich, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.