Altered regulation of hepatic glucose output in the male offspring of protein-malnourished rat dams

American Journal of Physiology - Endocrinology and Metabolism

Volumn 270, Issue 4 33-4, 1996, Pages

  Ozanne, S E ^a,b   Smith, G D ^a   Tikerpae, J ^a   Hales, C N ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

diabetes; glucagon; insulin resistance; liver

Indexed keywords

GLUCAGON; GLUCAGON RECEPTOR; GLUCOSE; GLUCOSE TRANSPORTER; INSULIN; INSULIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; GLUCONEOGENESIS; GLUCOSE HOMEOSTASIS; HORMONAL REGULATION; INSULIN BINDING; INSULIN DEGRADATION; INSULIN RESISTANCE; LIVER METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN MALNUTRITION; PROTEIN RESTRICTION; RAT;

EID: 0029972848     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1996.270.4.e559     Document Type: Article

References (34)

1. Athens, M., R. Valdez, and M. Stern. Effect of birth weight on future development of syndrome X in adult life (Abstract). Diabetes 42: 61, 1993.
2. Barker, D. J. P., C. N. Hales, C. H. D. Fall, C. Osmond, K. Phipps, and P. M. S. Clark. Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth. Diabetologia 36: 62-67, 1993.
3. Barker, D. J. P., P. D. Winter, C. Osmond, B. Margetts, and S. J. Simmonds. Weight in infancy and death from ischaemic heart disease. Lancet 2: 577-580, 1989.
4. Birnbaumer, L. Hormone sensitive adenyl cyclases, useful models for studying hormone receptor functions in cell free systems. Biochim. Biophys. Acta 30: 129-158, 1973.
5. Brant, A. M., S. M. McCoid, H. M. Thomas, S. A. Baldwin, A. Davies, J. C. Parker, E. M. Gibbs, and G. W. Gould. Analysis of the glucose transporter content of islet cell lines: implications for glucose-stimulated insulin release. Cell. Signal. 4: 641-650, 1992.
6. Brautigan, D. L., and J. D. Kuplic. Proposal for a pathway to mediate the metabolic effects of insulin. Int. J. Biochem. 20: 349-356, 1988.
7. Burcelin, R., M. Eddouks, J. Kande, R. Assan, and J. Girard. Evidence that GLUT-2 mRNA and protein concentrations are decreased by hyperinsulinaemia and increased by hyperglycaemia in liver of diabetic rats. Biochem. J. 288: 675-679, 1992.
8. Cherrington, A. D., P. E. Williams, G. I. Shulman, and W. W. Lacy. Differential time course of glucagon's effect on glycogenolysis and gluconeogenesis in the conscious dog. Diabetes 30: 180-187, 1981.
9. Christensen, J. R., G. D. Smith, and T. J. Peters. Chacterization of insulin uptake into subcellular fractions of perfused rat liver using two different iodinated tracers. Cell Biochem. Funct. 3: 13-19, 1985.
10. Dahri, S., A. Snoeck, B. Reusens-Billen, C. Remade, and J. J. Hoet. Islet function in offspring of mothers on low-protein diet during gestation. Diabetes 40: 115-120, 1991.
11. Davis, S. N., R. Dobbins, C. Tarumi, J. Jacobs, D. Neal, and A. D. Cherrington. Paradoxical insulin-induced increase in gluconeogenesis in response to prolonged hypoglycemia in conscious dogs. Am. J. Physiol. 268 (Endocrinol. Metab. 31): E521-E530, 1995.
12. Davis, S. N., R. E. Goldstein, J. Jacobs, L. Price, R. Wolfe, and A. D. Cherrington. The effects of differing insulin levels on the hormonal and metabolic response to equivalent hypoglycemia in normal humans. Diabetes 42: 263-272, 1993.
13. DeFronzo, R. A., R. C. Bonadonna, and E. Ferrannini. Pathogenesis of NIDDM: a balanced overview. Diabetes Care 15: 318-368, 1992.
14. Desai, M., N. J. Crowther, S. E. Ozanne, A. Lucas, and C. N. Hales. Adult glucose and lipid metabolism may be programmed during fetal life. Biochem. Soc. Trans. 23: 331-335, 1995.
15. Dorling, P. R., and R. N. LePage. A rapid high yield method for the preparation of rat liver cell plasma membranes. Biochim. Biophys. Acta 318: 33-44, 1973.
16. Exton, J. H., J. G. Corbin, and S. C. Harper. Control of gluconeogenesis in liver. V. Effects of fasting diabetes and glucagon on lactate and endogenous metabolism in the perfused rat liver. J. Biol. Chem. 247: 4996-5003, 1972
17. Hales, C. N., and D. J. P. Barker. Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia 35: 595-601, 1992.
18. Hales, C. N., D. J. P. Barker, P. M. S. Clark, L. J. Cox, C. Fall, C. Osmond, and P. D. Winter. Fetal and infant growth and impaired glucose tolerance at age 64. Br. Med. J. 303: 1019-1022, 1991.
19. Hutton, J. C., M. Peshavaria, C. F. Johnston, M. Ravazzola, and L. Orci. Immunolocalization of betagranin: A chromogranin A-related protein of the pancreatic B-cell. Endocrinology 122: 1014-1020, 1988.
20. Kunst, A., B. Draeger, and J. Ziegenhorn. UV methods with hexokinase and glucose-6-phosphate dehydrogenase. In: Methods of Enzymic Analysis, edited by H. U. Bergmeyer. Deerfield, FL: Verlag Chemie, 1983, p. 163-172.
21. Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature Lond. 227: 680-685, 1970.
22. Mackrell, D. J., and J. E. Sokal. Antagonism between the effects of insulin and glucagon on the isolated liver. Diabetes 18: 724-732, 1969.
23. McCance, D. R., D. J. Pettitt, R. L. Hanson, L. T. H. Jacobsson, W. C. Knowler, and P. H. Bennett. Birth weight and non-insulin dependent diabetes: thrifty genotype, thrifty phenotype, or surviving small baby genotype? Br. Med. J. 308: 942-945, 1994.
24. McGuinness, O. P., D. R. Green, and A. D. Cherrington. Glyburide sensitizes perfused rat liver to insulin induced suppression of glucose output. Diabetes 36: 472-476, 1987.
25. Munson, J. A., and D. Rodbard. LIGAND: a versatile computerized approach for characterization of ligand-binding systems. Anal. Biochem. 107: 220-239, 1980.
26. 125I-insulin binding in the liver of fed and fasted mice. Cell Mol. Biol. 41: 137-144, 1995.
27. Pease, R. J., G. D. Smith, and T. J. Peters. Degradation of endocytosed insulin in rat liver is mediated by low density vesicles. Biochem. J. 228: 137-146, 1985.
28. Phillips, D. I. W., D. J. P. Barker, C. N. Hales, S. Hirst, and C. Osmond. Thinness at birth and insulin resistance in adult life. Diabetologia 37: 150-154, 1994.
29. Rideout, J. M., G. D. Smith, C. K. Lim, and T. J. Peters. Comparative study of several phase systems for the high-performance liquid chromatographic seperation of monoiodoinsulins. Biochem. Soc. Trans. 13: 1225-1226, 1985.
30. Saltiel, A. R. The paradoxical regulation of protein phosphorylation in insulin action. FASEB J. 8: 1034-1040, 1994.
31. Schacterle, G. R., and R. L. Pollack. A simplified method for the quantitative assay of small amounts of protein in biologic material. Anal. Biochem. 51: 654-655, 1973.
32. Sivaprasadaro, A., and J. B. C. Findlay. Biochemical Membranes. A Practical Approach. Oxford, UK: IRL, 1987, p. 287-289.
33. Smith, G. D., J. R. Christensen, J. M. Rideout, and T. J. Peters. Hepatic processing of insulin. Characterization of differential inhibition by weak bases. Eur. J. Biochem. 181: 287-294, 1989.
34. Snoeck, A., C. Remacle, B. Reusens, and J. J. Hoet. Effect of a low protein diet during pregnancy on the fetal rat endocrine pancreas. Biol. Neonate 57: 107-118, 1990.