Brightfield Proximity Ligation Assay Reveals Both Canonical and Mixed Transforming Growth Factor-β/Bone Morphogenetic Protein Smad Signaling Complexes in Tissue Sections

Journal of Histochemistry and Cytochemistry

Volumn 62, Issue 12, 2014, Pages 846-863

  Flanders, Kathleen C ^a   Heger, Christopher D ^a   Conway, Catherine ^a   Tang, Binwu ^a   Sato, Misako ^a   Dengler, Samuel L ^a   Goldsmith, Paul K ^a   Hewitt, Stephen M ^a   Wakefield, Lalage M ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

breast cancer; brightfield; development; proximity ligation assay; Smads; tissue microarray; transforming growth factor

Indexed keywords

BETA ACTIN; BONE MORPHOGENETIC PROTEIN; PROTEIN ANTIBODY; SMAD PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMAD5 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; ANTIBODY;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; BREAST EPITHELIUM; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; HUMAN; HUMAN CELL; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MCF 7 CELL LINE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; TISSUE MICROARRAY; TISSUE SECTION; TUMOR XENOGRAFT; AMINO ACID SEQUENCE; ANIMAL; BREAST; BREAST TUMOR; EMBRYOLOGY; FEMALE; GENETICS; HISTOLOGY; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; PROCEDURES; PROTEIN ANALYSIS; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; TUMOR CELL LINE; UPREGULATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; BREAST; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; HISTOCYTOLOGICAL PREPARATION TECHNIQUES; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PROTEIN INTERACTION MAPPING; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 84912024890     PISSN: 00221554     EISSN: 15515044     Source Type: Journal    
DOI: 10.1369/0022155414550163     Document Type: Article

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