Short term fat feeding rapidly increases plasma insulin but does not result in dyslipidaemia

Frontiers in Physiology

Volumn 5, Issue Nov, 2014, Pages

  Barzel, Benjamin ^a,b   Weir, Jacquelyn M ^a   Meikle, Peter J ^a   Burke, Sandra L ^a   Armitage, James A ^a,b,c   Head, Geoffrey A ^a,b  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c DEAKIN UNIVERSITY   (Australia)

Author keywords

Hypertension; Insulin; Leptin; Obesity; Plasma lipids

Indexed keywords

CERAMIDE; CHOLESTEROL ESTER; DIACYLGLYCEROL; GLUCOSE; INSULIN; LEPTIN; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE MEASUREMENT; CONTROLLED STUDY; DYSLIPIDEMIA; FAT INTAKE; GLUCOSE BLOOD LEVEL; HEART RATE; HYPERTENSION; INSULIN BLOOD LEVEL; LIPID DIET; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NEW ZEALAND WHITE (RABBIT); NONHUMAN; OBESITY; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 84912011896     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2014.00469     Document Type: Article

References (30)

1. Air, E. L., S. C. Benoit, D. J. Clegg, R. J. Seeley, and S. C. Woods. (2002) Insulin and Leptin Combine Additively to Reduce Food Intake and Body Weight in Rats. Endocrinology 143, 2449-52.
2. Armitage, J A, S L Burke, L J Prior, B Barzel, N Eikelis, K Lim, et al. (2012) Rapid Onset of Renal Sympathetic Nerve Activation in Rabbits Fed a High-Fat Diet. Hypertension 60, 163-71.
3. Bagdade, J. D., E. L. Bierman, and D. Porte, Jr. (1967) The Significance of Basal Insulin Levels in the Evaluation of the Insulin Response to Glucose in Diabetic and Nondiabetic Subjects. J Clin Invest 46, 1549-57.
4. Bays, H. E. (2009) "Sick Fat," Metabolic Disease, and Atherosclerosis. Am J Med 122, S26-37.
5. Benoit, S. C., D. J. Clegg, R. J. Seeley, and S. C. Woods. (2004) Insulin and Leptin as Adiposity Signals. Recent Prog Horm Res. 59, 267-85.
6. Burke, S L, L J Prior, E V Lukoshkova, K Lim, B Barzel, PJ Davern, et al. (2013) Reduced Preprandial Dipping Accounts for Rapid Elevation of Blood Pressure and Renal Sympathetic Nerve Activity in Rabbits Fed a High-Fat Diet Chronobiol Int 30, 726-38.
7. Cameron, A. J., E. J. Boyko, R. A. Sicree, P. Z. Zimmet, S. Soderberg, K. G. Alberti, et al. (2008) Central Obesity as a Precursor to the Metabolic Syndrome in the Ausdiab Study and Mauritius. Obesity (Silver Spring) 16, 2707-16.
8. Considine, Robert V., Madhur K. Sinha, Mark L. Heiman, Aidas Kriauciunas, Thomas W. Stephens, Mark R. Nyce, et al. (1996) Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans. N Engl J Med 334, 292-95.
9. Cummings, D. E., J. Q. Purnell, R. S. Frayo, K. Schmidova, B. E. Wisse, and D. S. Weigle. (2001) A Preprandial Rise in Plasma Ghrelin Levels Suggests a Role in Meal Initiation in Humans. Diabetes 50, 1714-9.
10. Doi, H., K. Kugiyama, M. Ohgushi, S. Sugiyama, T. Matsumura, Y. Ohta, et al. (1998) Remnants of Chylomicron and Very Low Density Lipoprotein Impair Endothelium-Dependent Vasorelaxation. Atherosclerosis 137, 341-9.
11. Eppel, G A, J A Armitage, N Eikelis, G A Head, and R G Evans. (2013) Progression of Cardiovascular and Endocrine Dysfunction in a Rabbit Model of Obesity. Hypertension Res 36, 588-95.
12. Flaa, A., T. A. Aksnes, S. E. Kjeldsen, I. Eide, and M. Rostrup. (2008) Increased Sympathetic Reactivity May Predict Insulin Resistance: An 18-Year Follow-up Study. Metabolism 57, 1422-7.
13. Hamilton, R M, and K K Carroll. (1976) Plasma Cholesterol Levels in Rabbits Fed Low Fat, Low Cholesterol Diets: Effects of Dietary Proteins, Carbohydrates and Fibre from Different Sources. Atherosclerosis 24, 47-62.
14. Haus, J. M., S. R. Kashyap, T. Kasumov, R. Zhang, K. R. Kelly, R. A. Defronzo, et al. (2009) Plasma Ceramides Are Elevated in Obese Subjects with Type 2 Diabetes and Correlate with the Severity of Insulin Resistance. Diabetes 58, 337-43.
15. Landsberg, L. (1996) Insulin and the Sympathetic Nervous System in the Pathophysiology of Hypertension. Blood Press Suppl 1, 25-9.
16. Lim, K, S L Burke, and G A Head. (2013) Obesity Related Hypertension and the Role of Insulin and Leptin in High Fat Fed Rabbits. Hypertension 61, 628-34.
17. Lundman, P., P. Tornvall, L. Nilsson, and J. Pernow. (2001) A Triglyceride-Rich Fat Emulsion and Free Fatty Acids but Not Very Low Density Lipoproteins Impair Endothelium-Dependent Vasorelaxation. Atherosclerosis 159, 35-41.
18. Muntzel, MS, DA Morgan, AL Mark, and AK Johnson. (1994) Intracerebroventricular Insulin Produces Nonuniform Regional Increases in Sympathetic Nerve Activity. Am J Physiol Regul Integr Comp Physiol 36, R1350-R35.
19. Nguyen, N. T., C. P. Magno, K. T. Lane, M. W. Hinojosa, and J. S. Lane. (2008) Association of Hypertension, Diabetes, Dyslipidemia, and Metabolic Syndrome with Obesity: Findings from the National Health and Nutrition Examination Survey, 1999 to 2004. J Am Coll Surg 207, 928-34.
20. Pricher, M. P., K. L. Freeman, and V. L. Brooks. (2008) Insulin in the Brain Increases Gain of Baroreflex Control of Heart Rate and Lumbar Sympathetic Nerve Activity. Hypertension 51, 514-20.
21. Prior, LJ, N Eikelis, JA Armitage, PJ Davern, SL Burke, J-P Montani, et al. (2010) Exposure to a High-Fat Diet Alters Leptin Sensitivity and Elevates Renal Sympathetic Nerve Activity and Arterial Pressure in Rabbits. Hypertension 55, 862-68.
22. Sassolas, A., M. Vincent, D. Benzoni, and J. Sassard. (1981) Plasma Lipids in Genetically Hypertensive Rats of the Lyon Strain. J Cardiovasc Pharmacol 3, 1008-14.
23. Siri-Tarino, P. W., Q. Sun, F. B. Hu, and R. M. Krauss. (2010) Saturated Fat, Carbohydrate, and Cardiovascular Disease. Am J Clin Nutr 91, 502-9.
24. Sobotka, P. A., F. Mahfoud, M. P. Schlaich, U. C. Hoppe, M. Bohm, and H. Krum. (2011) Sympatho-Renal Axis in Chronic Disease. Clin Res Cardiol 1049-57.
25. Straznicky, N. E., G. W. Lambert, and E. A. Lambert. (2010) Neuroadrenergic Dysfunction in Obesity: An Overview of the Effects of Weight Loss. Curr Opin Lipidol 21, 21-30.
26. Vogel, R. A., M. C. Corretti, and G. D. Plotnick. (1997) Effect of a Single High-Fat Meal on Endothelial Function in Healthy Subjects. Am J Cardiol 79, 350-4.
27. Ward, K. R., J. F. Bardgett, L. Wolfgang, and S. D. Stocker. (2011) Sympathetic Response to Insulin Is Mediated by Melanocortin 3/4 Receptors in the Hypothalamic Paraventricular Nucleus. Hypertension.
28. Weir, J. M., G. Wong, C. K. Barlow, M. A. Greeve, A. Kowalczyk, L. Almasy, et al. (2013) Plasma Lipid Profiling in a Large Population-Based Cohort. J Lipid Res 54, 2898-908.
29. Weyer, C., T. Funahashi, S. Tanaka, K. Hotta, Y. Matsuzawa, R. E. Pratley, et al. (2001) Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance and Hyperinsulinemia. J Clin Endocrinol Metab 86, 1930-5.
30. Yuan, M., N. Konstantopoulos, J. Lee, L. Hansen, Z. W. Li, M. Karin, et al. (2001) Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkbeta. Science 293, 1673-7.