-
1
-
-
75149129597
-
From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis
-
Manolagas SC (2010) From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis. Endocr. Rev. 31, 266-300.
-
(2010)
Endocr. Rev.
, vol.31
, pp. 266-300
-
-
Manolagas, S.C.1
-
2
-
-
0031765564
-
Updated data on proximal femur bone mineral levels of US adults
-
Looker AC, Wahner HW, Dunn WL, Calvo MS, Harris TB, Heyse SP et al. (1998) Updated data on proximal femur bone mineral levels of US adults. Osteoporos. Int. 8, 468-489.
-
(1998)
Osteoporos. Int.
, vol.8
, pp. 468-489
-
-
Looker, A.C.1
Wahner, H.W.2
Dunn, W.L.3
Calvo, M.S.4
Harris, T.B.5
Heyse, S.P.6
-
3
-
-
38549094720
-
A population-based assessment of rates of bone loss at multiple skeletal sites: evidence for substantial trabecular bone loss in young adult women and men
-
Riggs BL, Melton LJ, Robb RA, Camp JJ, Atkinson EJ, McDaniel L et al. (2008) A population-based assessment of rates of bone loss at multiple skeletal sites: evidence for substantial trabecular bone loss in young adult women and men. J. Bone Miner. Res. 23, 205-214.
-
(2008)
J. Bone Miner. Res.
, vol.23
, pp. 205-214
-
-
Riggs, B.L.1
Melton, L.J.2
Robb, R.A.3
Camp, J.J.4
Atkinson, E.J.5
McDaniel, L.6
-
4
-
-
79953854757
-
Hard arteries, weak bones
-
Griffith JF, Kumta SM, Huang Y (2011) Hard arteries, weak bones. Skeletal Radiol. 40, 517-521.
-
(2011)
Skeletal Radiol.
, vol.40
, pp. 517-521
-
-
Griffith, J.F.1
Kumta, S.M.2
Huang, Y.3
-
5
-
-
79959497103
-
Soft bone - hard arteries: a link?
-
London GM (2011) Soft bone - hard arteries: a link? Kidney Blood Press. Res. 34, 203-208.
-
(2011)
Kidney Blood Press. Res.
, vol.34
, pp. 203-208
-
-
London, G.M.1
-
6
-
-
0030035678
-
Blood supply to the human femoral diaphysis in youth and senescense
-
Bridgeman G, Brookes M (1996) Blood supply to the human femoral diaphysis in youth and senescense. J. Anat. 188, 611-621.
-
(1996)
J. Anat.
, vol.188
, pp. 611-621
-
-
Bridgeman, G.1
Brookes, M.2
-
7
-
-
1842369617
-
MRI gadolinium enhancement of bone marrow: age-related changes in normals and in diffuse neoplastic infiltration
-
Baur A, Stabler A, Bartl R, Lamerz R, Scheidler J, Reiser M (1997) MRI gadolinium enhancement of bone marrow: age-related changes in normals and in diffuse neoplastic infiltration. Skeletal Radiol. 26, 414-418.
-
(1997)
Skeletal Radiol.
, vol.26
, pp. 414-418
-
-
Baur, A.1
Stabler, A.2
Bartl, R.3
Lamerz, R.4
Scheidler, J.5
Reiser, M.6
-
8
-
-
34948841571
-
Relationship between brachial arterial endothelial function and lumbar spine bone mineral density in postmenopausal women
-
Sumino H, Ichikawa S, Kasama S, Takahashi T, Sakamoto H, Kumakura H et al. (2007) Relationship between brachial arterial endothelial function and lumbar spine bone mineral density in postmenopausal women. Circ. J. 71, 1555-1559.
-
(2007)
Circ. J.
, vol.71
, pp. 1555-1559
-
-
Sumino, H.1
Ichikawa, S.2
Kasama, S.3
Takahashi, T.4
Sakamoto, H.5
Kumakura, H.6
-
9
-
-
34548079262
-
Aging reduces skeletal blood flow, endothelium-dependent vasodilation, and NO bioavailability in rats
-
Prisby RD, Ramsey MW, Behnke BJ, Dominguez JM 2nd, Donato AJ, Allen MR et al. (2007) Aging reduces skeletal blood flow, endothelium-dependent vasodilation, and NO bioavailability in rats. J. Bone Miner. Res. 22, 1280-1288.
-
(2007)
J. Bone Miner. Res.
, vol.22
, pp. 1280-1288
-
-
Prisby, R.D.1
Ramsey, M.W.2
Behnke, B.J.3
Dominguez II, J.M.4
Donato, A.J.5
Allen, M.R.6
-
10
-
-
78650727785
-
Reduced local blood supply to the tibial metaphysis is associated with ovariectomy-induced osteoporosis in mice
-
Ding WG, Wei ZX, Liu JB (2011) Reduced local blood supply to the tibial metaphysis is associated with ovariectomy-induced osteoporosis in mice. Connect. Tissue Res. 52, 25-29.
-
(2011)
Connect. Tissue Res.
, vol.52
, pp. 25-29
-
-
Ding, W.G.1
Wei, Z.X.2
Liu, J.B.3
-
11
-
-
77953271453
-
Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice
-
Weinstein RS, Wan C, Liu Q, Wang Y, Almeida M, O'Brien CA et al. (2010) Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice. Aging Cell 9, 147-161.
-
(2010)
Aging Cell
, vol.9
, pp. 147-161
-
-
Weinstein, R.S.1
Wan, C.2
Liu, Q.3
Wang, Y.4
Almeida, M.5
O'Brien, C.A.6
-
12
-
-
84884803160
-
A systematic review of the efficacy and pharmacological profile of Herba Epimedii in osteoporosis therapy
-
Zhai YK, Guo X, Pan YL, Niu YB, Li CR, Wu XL et al. (2013) A systematic review of the efficacy and pharmacological profile of Herba Epimedii in osteoporosis therapy. Pharmazie 68, 713-722.
-
(2013)
Pharmazie
, vol.68
, pp. 713-722
-
-
Zhai, Y.K.1
Guo, X.2
Pan, Y.L.3
Niu, Y.B.4
Li, C.R.5
Wu, X.L.6
-
13
-
-
62549091847
-
Antiosteoporotic activity of icariin in ovariectomized rats
-
Nian H, Ma MH, Nian SS, Xu LL (2009) Antiosteoporotic activity of icariin in ovariectomized rats. Phytomedicine 16, 320-326.
-
(2009)
Phytomedicine
, vol.16
, pp. 320-326
-
-
Nian, H.1
Ma, M.H.2
Nian, S.S.3
Xu, L.L.4
-
14
-
-
77249175670
-
Icariin protects against bone loss induced by oestrogen deficiency and activates oestrogen receptor-dependent osteoblastic functions in UMR 106 cells
-
Mok SK, Chen WF, Lai WP, Leung PC, Wang XL, Yao XS et al. (2010) Icariin protects against bone loss induced by oestrogen deficiency and activates oestrogen receptor-dependent osteoblastic functions in UMR 106 cells. Br. J. Pharmacol. 159, 939-949.
-
(2010)
Br. J. Pharmacol.
, vol.159
, pp. 939-949
-
-
Mok, S.K.1
Chen, W.F.2
Lai, W.P.3
Leung, P.C.4
Wang, X.L.5
Yao, X.S.6
-
15
-
-
84906933880
-
Icariin prevents ovariectomy-induced bone loss and lowers marrow adipogenesis
-
Epub ahead of print
-
Li GW, Xu Z, Chang SX, Nian H, Wang XY, Qin LD (2014) Icariin prevents ovariectomy-induced bone loss and lowers marrow adipogenesis. Menopause 21, 1007-1016. [Epub ahead of print]
-
(2014)
Menopause
, vol.21
, pp. 1007-1016
-
-
Li, G.W.1
Xu, Z.2
Chang, S.X.3
Nian, H.4
Wang, X.Y.5
Qin, L.D.6
-
16
-
-
34548577294
-
Epimedium-derived phytoestrogen flavonoids exert beneficial effect on preventing bone loss in late postmenopausal women: a 24-month randomized, double-blind and placebo-controlled trial
-
Zhang G, Qin L, Shi Y (2007) Epimedium-derived phytoestrogen flavonoids exert beneficial effect on preventing bone loss in late postmenopausal women: a 24-month randomized, double-blind and placebo-controlled trial. J. Bone Miner. Res. 22, 1072-1079.
-
(2007)
J. Bone Miner. Res.
, vol.22
, pp. 1072-1079
-
-
Zhang, G.1
Qin, L.2
Shi, Y.3
-
17
-
-
84868195814
-
Herba epimedii flavonoids suppress osteoclastic differentiation and bone resorption by inducing G2/M arrest and apoptosis
-
Zhang D, Zhang J, Fong C, Yao X, Yang M (2012) Herba epimedii flavonoids suppress osteoclastic differentiation and bone resorption by inducing G2/M arrest and apoptosis. Biochimie 94, 2514-2522.
-
(2012)
Biochimie
, vol.94
, pp. 2514-2522
-
-
Zhang, D.1
Zhang, J.2
Fong, C.3
Yao, X.4
Yang, M.5
-
18
-
-
84879478532
-
Icariin induces osteoblast proliferation, differentiation and mineralization through estrogen receptor-mediated ERK and JNK signal activation
-
Song L, Zhao J, Zhang X, Li H, Zhou Y (2013) Icariin induces osteoblast proliferation, differentiation and mineralization through estrogen receptor-mediated ERK and JNK signal activation. Eur. J. Pharmacol. 714, 15-22.
-
(2013)
Eur. J. Pharmacol.
, vol.714
, pp. 15-22
-
-
Song, L.1
Zhao, J.2
Zhang, X.3
Li, H.4
Zhou, Y.5
-
19
-
-
79951804968
-
Icarrin is more potent than genistein in promoting osteoblast differentiation and mineralization in vitro
-
Ma HP, Ming LG, Ge BF, Zhai YK, Song P, Xian CJ et al. (2011) Icarrin is more potent than genistein in promoting osteoblast differentiation and mineralization in vitro. J. Cell. Biochem. 112, 916-923.
-
(2011)
J. Cell. Biochem.
, vol.112
, pp. 916-923
-
-
Ma, H.P.1
Ming, L.G.2
Ge, B.F.3
Zhai, Y.K.4
Song, P.5
Xian, C.J.6
-
20
-
-
84870447931
-
Function and action mechanism of flavoids genistein and icariin in regulating bone remodeling
-
Ming LG, Chen KM, Xian CJ (2013) Function and action mechanism of flavoids genistein and icariin in regulating bone remodeling. J. Cell. Physiol. 228, 513-521.
-
(2013)
J. Cell. Physiol.
, vol.228
, pp. 513-521
-
-
Ming, L.G.1
Chen, K.M.2
Xian, C.J.3
-
21
-
-
84862982949
-
Cadmium activates a programmed, lysosomal membrane permeabilization-dependent necrosis pathway
-
Messner B, Ploner C, Laufer G, Bernhard D (2012) Cadmium activates a programmed, lysosomal membrane permeabilization-dependent necrosis pathway. Toxicol. Lett. 212, 268-275.
-
(2012)
Toxicol. Lett.
, vol.212
, pp. 268-275
-
-
Messner, B.1
Ploner, C.2
Laufer, G.3
Bernhard, D.4
-
22
-
-
80052287777
-
Effects of 50Hz sinusoidal electromagnetic fields of different intensities on proliferation, differentiation and mineralization potentials of rat osteoblasts
-
Zhou J, Ming LG, Ge BF, Wang JQ, Zhu RQ, Wei Z et al. (2011) Effects of 50Hz sinusoidal electromagnetic fields of different intensities on proliferation, differentiation and mineralization potentials of rat osteoblasts. Bone 49, 753-761.
-
(2011)
Bone
, vol.49
, pp. 753-761
-
-
Zhou, J.1
Ming, L.G.2
Ge, B.F.3
Wang, J.Q.4
Zhu, R.Q.5
Wei, Z.6
-
23
-
-
78149361469
-
Mitochondria and GSK-3β in cardioprotection against ischemia/reperfusion injury
-
Miura T, Tanno M (2010) Mitochondria and GSK-3β in cardioprotection against ischemia/reperfusion injury. Cardiovasc. Drugs Ther. 24, 255-263.
-
(2010)
Cardiovasc. Drugs Ther.
, vol.24
, pp. 255-263
-
-
Miura, T.1
Tanno, M.2
-
24
-
-
0042564805
-
ROS-dependent caspase-9 activation in hypoxic cell death
-
Kim JY, Park JH (2003) ROS-dependent caspase-9 activation in hypoxic cell death. FEBS Lett. 549, 94-98.
-
(2003)
FEBS Lett.
, vol.549
, pp. 94-98
-
-
Kim, J.Y.1
Park, J.H.2
-
25
-
-
0035914140
-
Association between oxidative stress and bone mineral density
-
Basu S, Michaelsson K, Olofsson H, Johansson S, Melhus H (2001) Association between oxidative stress and bone mineral density. Biochem. Biophys. Res. Commun. 288, 275-279.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.288
, pp. 275-279
-
-
Basu, S.1
Michaelsson, K.2
Olofsson, H.3
Johansson, S.4
Melhus, H.5
-
26
-
-
11144248825
-
Tumor necrosis factor-α mediates osteopenia caused by depletion of antioxidants
-
Jagger CJ, Lean JM, Davies JT, Chambers TJ (2005) Tumor necrosis factor-α mediates osteopenia caused by depletion of antioxidants. Endocrinology 146, 113-118.
-
(2005)
Endocrinology
, vol.146
, pp. 113-118
-
-
Jagger, C.J.1
Lean, J.M.2
Davies, J.T.3
Chambers, T.J.4
-
27
-
-
38049021536
-
Total oxidative/anti-oxidative status and relation to bone mineral density in osteoporosis
-
Altindag O, Erel O, Soran N, Celik H, Selek S (2008) Total oxidative/anti-oxidative status and relation to bone mineral density in osteoporosis. Rheumatol. Int. 28, 317-321.
-
(2008)
Rheumatol. Int.
, vol.28
, pp. 317-321
-
-
Altindag, O.1
Erel, O.2
Soran, N.3
Celik, H.4
Selek, S.5
-
28
-
-
33745161881
-
Antioxidant vitamin supplements and markers of bone turnover in a community sample of nonsmoking women
-
Pasco JA, Henry MJ, Wilkinson LK, Nicholson GC, Schneider HG, Kotowicz MA (2006) Antioxidant vitamin supplements and markers of bone turnover in a community sample of nonsmoking women. J. Womens. Health (Larchmt) 15, 295-300.
-
(2006)
J. Womens. Health (Larchmt)
, vol.15
, pp. 295-300
-
-
Pasco, J.A.1
Henry, M.J.2
Wilkinson, L.K.3
Nicholson, G.C.4
Schneider, H.G.5
Kotowicz, M.A.6
-
29
-
-
34548828242
-
Potential role of the antioxidant N-acetylcysteine in slowing bone resorption in early post-menopausal women: a pilot study
-
Sanders KM, Kotowicz MA, Nicholson GC (2007) Potential role of the antioxidant N-acetylcysteine in slowing bone resorption in early post-menopausal women: a pilot study. Trans. Res. 150, 215.
-
(2007)
Trans. Res.
, vol.150
, pp. 215
-
-
Sanders, K.M.1
Kotowicz, M.A.2
Nicholson, G.C.3
-
30
-
-
33745452380
-
Icariin: a special antioxidant to protect linoleic acid against free-radical-induced peroxidation in micelles
-
Liu ZQ (2006) Icariin: a special antioxidant to protect linoleic acid against free-radical-induced peroxidation in micelles. J. Phys. Chem. A 110, 6372-6378.
-
(2006)
J. Phys. Chem. A
, vol.110
, pp. 6372-6378
-
-
Liu, Z.Q.1
-
31
-
-
20444485642
-
Protective effects of icariin on human umbilical vein endothelial cell injury induced by H2O2 in vitro
-
Wang YK, Huang ZQ (2005) Protective effects of icariin on human umbilical vein endothelial cell injury induced by H2O2 in vitro. Pharmacol. Res. 52, 174-182.
-
(2005)
Pharmacol. Res.
, vol.52
, pp. 174-182
-
-
Wang, Y.K.1
Huang, Z.Q.2
-
32
-
-
10044267633
-
The antioxidative effect of icariin in human erythrocytes against free-radical-induced haemolysis
-
Liu ZQ, Luo XY, Sun YX, Wu W, Liu CM, Liu ZQ et al. (2004) The antioxidative effect of icariin in human erythrocytes against free-radical-induced haemolysis. J. Pharm. Pharmacol. 56, 1557-1562.
-
(2004)
J. Pharm. Pharmacol.
, vol.56
, pp. 1557-1562
-
-
Liu, Z.Q.1
Luo, X.Y.2
Sun, Y.X.3
Wu, W.4
Liu, C.M.5
Liu, Z.Q.6
-
33
-
-
36849000237
-
Protective effect of icariin on DNA against radical-induced oxidative damage
-
Zhao F, Tang YZ, Liu ZQ (2007) Protective effect of icariin on DNA against radical-induced oxidative damage. J. Pharm. Pharmacol. 59, 1729-1732.
-
(2007)
J. Pharm. Pharmacol.
, vol.59
, pp. 1729-1732
-
-
Zhao, F.1
Tang, Y.Z.2
Liu, Z.Q.3
-
34
-
-
68549115432
-
Protective effects of icariin on cognitive deficits induced by chronic cerebral hypoperfusion in rats
-
Xu RX, Wu Q, Luo Y, Gong QH, Yu LM, Huang XN et al. (2009) Protective effects of icariin on cognitive deficits induced by chronic cerebral hypoperfusion in rats. Clin. Exp. Pharmacol. Physiol. 36, 810-815.
-
(2009)
Clin. Exp. Pharmacol. Physiol.
, vol.36
, pp. 810-815
-
-
Xu, R.X.1
Wu, Q.2
Luo, Y.3
Gong, Q.H.4
Yu, L.M.5
Huang, X.N.6
-
35
-
-
78649601721
-
Icariin inhibits hydrogen peroxide-mediated cytotoxicity by up-regulating sirtuin type 1-dependent catalase and peroxiredoxin
-
Zhang L, Huang S, Chen Y, Wang Z, Li E, Xu Y (2010) Icariin inhibits hydrogen peroxide-mediated cytotoxicity by up-regulating sirtuin type 1-dependent catalase and peroxiredoxin. Basic Clin. Pharmacol. Toxicol. 107, 899-905.
-
(2010)
Basic Clin. Pharmacol. Toxicol.
, vol.107
, pp. 899-905
-
-
Zhang, L.1
Huang, S.2
Chen, Y.3
Wang, Z.4
Li, E.5
Xu, Y.6
-
36
-
-
84883475989
-
Icariin protects rat cardiac H9c2 cells from apoptosis by inhibiting endoplasmic reticulum stress
-
Zhang Q, Li H, Wang S, Liu M, Feng Y, Wang X (2013) Icariin protects rat cardiac H9c2 cells from apoptosis by inhibiting endoplasmic reticulum stress. Int. J. Mol. Sci. 14, 17845-17860.
-
(2013)
Int. J. Mol. Sci.
, vol.14
, pp. 17845-17860
-
-
Zhang, Q.1
Li, H.2
Wang, S.3
Liu, M.4
Feng, Y.5
Wang, X.6
-
37
-
-
0034455103
-
Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis
-
Manolagas SC (2000) Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocr. Rev. 21, 115-137.
-
(2000)
Endocr. Rev.
, vol.21
, pp. 115-137
-
-
Manolagas, S.C.1
-
38
-
-
58349120683
-
Apoptosis and bone cells
-
Bilezikian JP, Raisz LG, Martin T, eds. San Diego, CA: Academic Press.
-
Jilka RL, Bellido T, Almeida M, Plotkin LI, O'Brien CA, Weinstein RS et al. (2008). Apoptosis and bone cells. In: Bilezikian JP, Raisz LG, Martin T, eds. Principles of Bone Biology, pp. 235-259. San Diego, CA: Academic Press.
-
(2008)
Principles of Bone Biology
, pp. 235-259
-
-
Jilka, R.L.1
Bellido, T.2
Almeida, M.3
Plotkin, L.I.4
O'Brien, C.A.5
Weinstein, R.S.6
-
39
-
-
84887433210
-
Icariin induces osteoblast differentiation and mineralization without dexamethasone in vitro
-
Ma XN, Zhou J, Ge BF, Zhen P, Ma HP, Shi WG et al. (2013) Icariin induces osteoblast differentiation and mineralization without dexamethasone in vitro. Planta Med. 79, 1501-1508.
-
(2013)
Planta Med.
, vol.79
, pp. 1501-1508
-
-
Ma, X.N.1
Zhou, J.2
Ge, B.F.3
Zhen, P.4
Ma, H.P.5
Shi, W.G.6
-
41
-
-
80053214204
-
Resveratrol promotes osteogenesis of human mesenchymal stem cells by upregulating Runx2 gene expression via the Sirt1/Foxo3A axis
-
Tseng PC, Hou SM, Chen RJ, Peng HW, Hsieh CF, Kuo ML et al. (2011) Resveratrol promotes osteogenesis of human mesenchymal stem cells by upregulating Runx2 gene expression via the Sirt1/Foxo3A axis. J. Bone Miner. Res. 26, 2552-2563.
-
(2011)
J. Bone Miner. Res.
, vol.26
, pp. 2552-2563
-
-
Tseng, P.C.1
Hou, S.M.2
Chen, R.J.3
Peng, H.W.4
Hsieh, C.F.5
Kuo, M.L.6
-
42
-
-
84890962623
-
Icaritin attenuates cigarette smoke-mediated oxidative stress in human lung epithelial cells via activation of PI3K-AKT and Nrf2 signaling
-
Wu J, Xu H, Wong PF, Xia S, Xu J, Dong J (2014) Icaritin attenuates cigarette smoke-mediated oxidative stress in human lung epithelial cells via activation of PI3K-AKT and Nrf2 signaling. Food Chem. Toxicol. 64, 307-313.
-
(2014)
Food Chem. Toxicol.
, vol.64
, pp. 307-313
-
-
Wu, J.1
Xu, H.2
Wong, P.F.3
Xia, S.4
Xu, J.5
Dong, J.6
-
43
-
-
84890554973
-
Nrf2-dependent upregulation of antioxidative enzymes: a novel pathway for hypoxic preconditioning-mediated delayed cardioprotection
-
Huang XS, Chen HP, Yu HH, Yan YF, Liao ZP, Huang QR (2014) Nrf2-dependent upregulation of antioxidative enzymes: a novel pathway for hypoxic preconditioning-mediated delayed cardioprotection. Mol. Cell. Biochem. 385, 33-41.
-
(2014)
Mol. Cell. Biochem.
, vol.385
, pp. 33-41
-
-
Huang, X.S.1
Chen, H.P.2
Yu, H.H.3
Yan, Y.F.4
Liao, Z.P.5
Huang, Q.R.6
-
44
-
-
43649093915
-
Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway
-
Kaelin WG Jr, Ratcliffe PJ (2008) Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. Mol. Cell 30, 393-402.
-
(2008)
Mol. Cell
, vol.30
, pp. 393-402
-
-
Kaelin Jr, W.G.1
Ratcliffe, P.J.2
-
45
-
-
84876860824
-
HIF-1α confers resistance to induced stress in bone marrow-derived mesenchymal stem cells
-
Kiani AA, Kazemi A, Halabian R, Mohammadipour M, Jahanian-Najafabadi A, Roudkenar MH (2013) HIF-1α confers resistance to induced stress in bone marrow-derived mesenchymal stem cells. Arch. Med. Res. 44, 185-193.
-
(2013)
Arch. Med. Res.
, vol.44
, pp. 185-193
-
-
Kiani, A.A.1
Kazemi, A.2
Halabian, R.3
Mohammadipour, M.4
Jahanian-Najafabadi, A.5
Roudkenar, M.H.6
|